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Medical Sains : Jurnal Ilmiah Kefarmasian
Published by Universitas Muhammadiyah Ahmad Dahlan Cirebon
ISSN : 25482114     EISSN : 25412027     DOI : https://doi.org/10.37874/ms
Core Subject : Health,
Medicine & Pharmacology
The Medical Sains journal is a scientific publication media published by the Muhammadiyah Cirebon College of Pharmacy which is published 4 (four) times in 1 (one) year, namely January-March, April-June, July-September and October-December. The journal contains research in the field of pharmacy covering the fields of formulation, pharmacology, communication pharmacy, A natural chemical chemistry, pharmacognomy and other health sciences which is a means for lecturers and researchers in the health sector to share knowledge and establish cooperation in implementing the Tri Dharma of Higher Education. Purpose and Scope The objective of the publication of the Medical Science journal is to publish articles in the field of pharmacy and other health as well as application of pharmaceutical . Based on this, the editorial board of Medical Sains invites lecturers and researchers to contribute to submit research articles related to the following themes: 1. Pharmaceutical formulation technology 2. Pharmacology 3. Community pharmacy 4. Clinical Pharmacy 5. Natural material chemistry 6. Pharmacognosy 7. Pharmaceutical Analysis and Medicinal Chemistry . All papers submitted to medical science journals will be examined by peer review partners who are tailored to their respective fields.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 42 Documents
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Search results for , issue "Vol 8 No 3 (2023)" : 42 Documents clear
NANOEMULSION-BASED MOUTHWASH OF ETHYL ACETATE FRACTION OF SERAI WANGI STALK: FORMULATION, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY TEST Desy Ayu Irma Permatasari; Weri Veranita; Novalisa Nindhi Soraya; Eva Kholifah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.908

Abstract

Serai wangi or citronella (Cymbopogon nardus L.) has long been used in Indonesia as a component of traditional medicine. A recent study aimed to determine the antibacterial activity of the most active fraction of Citronella stalk extract and to formulate it  into a nanoemulsion mouthwash. Fractionation of the ethanolic extract was carried out using liquid-liquid extraction, and it was found that the ethyl acetate fraction (EAF) was the most active. This fraction was then varied at concentrations of 25%, 12.5%, 6.25%, 3.125%, 1.5625%, and 0.78125% for the antibacterial activity test using the disc diffusion test method. To determine the potency of microbial activity, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated. Subsequently, the ethyl acetate fraction was formulated into a nanoemulsion and characterized by measuring the transmittance percentage, droplet size, and polydispersity index (pdI) using a particle size analyzer. The results showed that the ethyl acetate fraction at a concentration of 25% obtained an inhibition zone diameter of 10.67 mm. MIC and MBC values ??were obtained at a fraction concentration of 6.25%. In addition, characterization of formulae exhibited particle size and pdI as follow 101.6 nm and 0.681 (Formula I); 84.1 nm and 0.609 (Formula II); 108.3 nm and 0.527 (Formula III).  Keywords:  Citronella stalk; fractionation; Streptococcus mutans; nano-emulsion; mouth wash
SYSTEMATIC LITERATUR REVIEW: SYNTHESIS OF SILVER NANOPARTICLES (AgNPs) USING SECONDARY METABOLITES OF FRUIT PEEL EXTRACT Indana Lazulfa; Erindyah Retno Wikantyasning
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.913

Abstract

The synthesis of silver nanoparticles (AgNPs) using secondary metabolites of biological materials is a simple, cost-effective, and environmentally friendly method compared to physical synthesis methods. The secondary metabolites of the fruit peel extract can be used to synthesize AgNPs. Researchers chose experimental research articles with the theme of silver nanoparticle synthesis using fruit peels for review and selected journals published from 2018 to 2022 from web searches PubMed, Google Schoolar, Scopus, and ScienceDirect. The researchers screened and selected 28 articles according to the inclusion and exclusion criteria. The synthesis of AgNPs using fruit peel extracts can produce stable nanosized AgNPs. Silver nanoparticles synthesized using fruit peels showed stable silver nanoparticle synthesis results in terms of zeta potential and polydispersity index (PDI) values and obtained an average size of 2–200 nm with a spherical shape. Keywords: Silver Nanoparticles, Fruit Peel Extract, Antibacterial agent

Page 5 of 5 | Total Record : 42

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