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All Journal Pharmasipha Medical Sains : Jurnal Ilmiah Kefarmasian Indonesian Journal on Medical Science (IJMS) Indonesian Journal of Medical Chemistry and Bioinformatics Proceeding of International Conference Health, Science And Technology (ICOHETECH) JURNAL FARMASI DAN KESEHATAN INDONESIA Parapemikir Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal) Jurnal Ilmiah Farmasi Indonesia (JIFIN)
Veranita, Weri
Fakultas Farmasi, Universitas Pancasila, Jalan Raya Lenteng Agung Srengseng Sawah, Jakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Physics Public Health

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Hubungan Antara Konsumsi Tablet Fe Saat Menstruasi dengan Kejadian Anemia pada Remaja Putri di Desa Wirengan Masaran Sragen Anik Sulistiyanti; Ana Yuliana; Weri Veranita
Indonesian Journal on Medical Science Vol 9 No 1 (2022): IJMS 2022
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.187 KB) | DOI: 10.55181/ijms.v9i1.358

Abstract

Anemia in women generally occurs during menstruation, pregnancy, childbirth, postpartum and breastfeeding in a woman's reproductive cycle. In young women, anemia problems will appear due to malnutrition or during menstrual conditions. The main cause of anemia in women is the decreased intake of foods made from iron (Fe) so that the need for iron (Fe) increases due to blood loss during menstruation. The purpose of this study was to determine the relationship between consumption of Fe tablets during menstruation and the incidence of anemia in adolescent girls in the village of Wirengan Masaran, Sragen. The research method used was analytical research with a cross sectional approach. Using simple random sampling technique with a sample of 50 female adolescent girls in Wirengan Masaran Village. The research instrument was examination of anemia, administration of Fe tablets and digital HB measurements. Data analysis used univariate analysis and bivariate analysis, namely chi quare. The results showed that 18 respondents (16.0%) were not anemic and who took Fe tablets during menstruation, while 19 respondents were anemic and did not consume Fe tablets. Based on the results of the Chi Square test, the p value = 0.003 < 0.05 with p value can be concluded that Ha is accepted. There was a relationship between consumption of Fe tablets during menstruation and the incidence of anemia in adolescent girls in the village of Wirengan Masaran, Sragen.
Literature Review: Hand sanitizer formulation from extract and essential oil of betel leaf (Piper betle Linn.) As well as antibacterial activity test Weri veranita; Kusumaningtyas Siwi Artini; Danang Raharjo; Ferry Effendi
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (429.774 KB) | DOI: 10.47701/icohetech.v1i1.1074

Abstract

The pandemic encourages us to look for various ways to overcome it, from various sides, including physical mobility management, vaccine development, to drug discovery. Indonesia has long recognized and used medicinal plants as an effort to overcome health efforts. Piper betle Linn or betel is a plant known to have antiseptic properties. Traditional use is usually by boiling the betel leaf. Utilization of stew and betel leaf extract as natural antibacterial agents has advantages. This is because these plants have natural compounds that are safer than the use of drugs that contain synthetic ingredients. Research reveals that betel leaf with an extract content of more than 15% is equivalent to alcohol and ethanol content. Research and utilization of betel leaf as an antiseptic and hand sanitizer products have been done a lot, one of which is by using extracts and essential oils from betel leaves. The aim of this study was to compare the antibacterial activity of the betel leaf hand sanitizer formulation using extracts and essential oils against the tested bacteria. This research is a literature review. Information on the hand sanitizer formulation of Piper betle Linn betel leaf was collected from online databases such as Pub Med, Direct Scient, and Google Scholar.
Literature Review: The Potencial Effect of Dandang Gendis Leave (Clinacanthus nutans Lindau) Kusumaningtyas Siwi Artini; Weri Veranita; Tatiana Siska Wardani
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (704.505 KB) | DOI: 10.47701/icohetech.v1i1.1076

Abstract

Indonesian are used to use herb to medicate a disease. One of the medicinal plants used is Clinacnathus nutans (Burm.f.) Lindau. Clinacnathus nutans Lindau is a traditional plant, commonly known as dandang gendhis (Java – Indonesia), ki tajam (Sunda – Indonesia), belalai gajah (Malaysia), Sabah Snake Grass (Singapore), and phaya yo (Thailand). It belonging to the Acanthaceae family. This study aimed to find out the the effect of giving the extract of Clinacnathus nutans Lindau to subject. This research method was using literature review. The information about Clinacanthus nutans Lindau collected from an online database such as Pub Med, Scient direct and Google Scholar. The number of chemical compound were identified from leaves. It contain of alkaloid, flavonoid, polifenol, saponin and tanin Some of the potential effect shown such as antihypoglycemic, antioxidant and anticancer, and analgetic. In this study,we can conclude that in the future Clinacnathus nutans Lindau is valuable to use as herbal medicine with more investigation.
Formulation and evaluation of antibacterial nanoemulsion mouthwash from active fraction of lemongrass stem (Cymbopogon Nardus) Weri Veranita; Desy Ayu Irma Permatasari
Proceeding of International Conference on Science, Health, And Technology Proceeding of the 3rd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (457.017 KB) | DOI: 10.47701/icohetech.v3i1.2277

Abstract

Currently, the use of pharmaceutical preparations based on natural ingredients has begun to be in great demand by the public. This is because the use of synthetic drugs has weaknesses such as being able to cause resistance. Dental caries is one of the most common oral diseases in humans. One of the plants that has the potential to be used as an antibacterial in the oral cavity is Lemongrass (Cymbopogon Nardus L.). The use of emulsion mouthwash in the oral cavity is one of the treatments that is still being carried out. Mouthwash with nano size has advantages such as being able to enter the body more easily. This study aims to determine the physical properties of mouthwash nanoemulsion ethyl acetate extract of Serai Wangi (Cymbopogon Nardus L.) by evaluating the preparation. The nanoemulsion mouthwash was made with the composition of Palm Oil as the oil phase, 96% ethanol as the cosurfactant, Tween 80 as the surfactant, and phosphate buffer pH 6 as the water phase. Then the mixture was stirred at a speed of 1000 rpm and sonicated and then tested for evaluation of the preparation including pH test, homogeneity test, organoleptic test, centrifugation test and transmittance test using UV-Vis Spectrophotometer. The results of the analysis of the entire nanoemulsion formula showed that the more the mangosteen rind extract was incorporated into the oil phase, the more concentrated the color of the nanoemulsion formed and the smaller the percentage of transmittance produced.
NANOEMULSION-BASED MOUTHWASH OF ETHYL ACETATE FRACTION OF SERAI WANGI STALK: FORMULATION, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY TEST Desy Ayu Irma Permatasari; Weri Veranita; Novalisa Nindhi Soraya; Eva Kholifah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.908

Abstract

Serai wangi or citronella (Cymbopogon nardus L.) has long been used in Indonesia as a component of traditional medicine. A recent study aimed to determine the antibacterial activity of the most active fraction of Citronella stalk extract and to formulate it  into a nanoemulsion mouthwash. Fractionation of the ethanolic extract was carried out using liquid-liquid extraction, and it was found that the ethyl acetate fraction (EAF) was the most active. This fraction was then varied at concentrations of 25%, 12.5%, 6.25%, 3.125%, 1.5625%, and 0.78125% for the antibacterial activity test using the disc diffusion test method. To determine the potency of microbial activity, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated. Subsequently, the ethyl acetate fraction was formulated into a nanoemulsion and characterized by measuring the transmittance percentage, droplet size, and polydispersity index (pdI) using a particle size analyzer. The results showed that the ethyl acetate fraction at a concentration of 25% obtained an inhibition zone diameter of 10.67 mm. MIC and MBC values ??were obtained at a fraction concentration of 6.25%. In addition, characterization of formulae exhibited particle size and pdI as follow 101.6 nm and 0.681 (Formula I); 84.1 nm and 0.609 (Formula II); 108.3 nm and 0.527 (Formula III).  Keywords:  Citronella stalk; fractionation; Streptococcus mutans; nano-emulsion; mouth wash
EFEKTIVITAS FORMULASI SABUN CUCI TANGAN KERTAS ANTIBAKTERI DARI KOMBINASI MINYAK ATSIRI DARI AMPAS JERUK KALAMANSI (Citrofortunella microcarpa) DAN EKSTRAK TEH HIJAU (Camellia sinensis L) weri veranita
Parapemikir : Jurnal Ilmiah Farmasi Vol 11, No 1 (2022): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v11i1.3213

Abstract

Era pandemic Covid19 Abstrak mengubah banyak perilaku masyarakat untuk lebih sadar dan disiplin terhadap kesehatan dan kebersihan dan kesadaran masyarakat untuk mencuci tangan. Hingga saat ini inovasi dalam pembuatan sabun cuci tangan terus dilakukan salah satunya dengan menggunakan sediaan sabun kertas sekali pakai yang akan larut saat terkena air dan akan mengeluarkan busa saat di gosokkan. Penambahan bahan alam berkhasiat sebagai antibakteri di tambahkan pada formulasi ini yaitu  minyak atsiri dari ampas jeruk kalamansi (Citrusfortunela microcarpa) dan esktak teh hijau (Camellia sinensis L). Menurut penelitian sebelumnya dari hasil pengujian antibakteri dari kombinasi minyak atsiri jeruk kalamansi (Citrusfortunela microcarpa) dan teh hijau (Camellia sinensis L) pada konsentrasi 1,5% memberikan antibakteri efek antibakteri pada bakteri uji Staphylococcus aureus dengan  diameter hambat sebesar 17,3mm. Antioksidan dan tanin acid pada teh hijau diharapkan selain memberikan efek antibakteri juga memberikan efek segar pada saat sediaan di aplikasikan pada kulit. Pada penelitian ini formulasi sediaan terlebih dahulu dibuat dalam bentuk sabun cair, setelah sediaan terbentuk dilakukan pencetakan sabun kertas lalu dilakukan pengujian efektifitas sediaan sabun cuci tangan kertas. Hasil menunjukkan bahwa pada pengujian bakteri uji S. aureus dan E. coli konsentrasi tertinggi formula 3 dengan perbandingan minyak atsiri dan esktrak teh hijau 1:1 konsetrasi 1,5% dengan diameter hambat 17,5mm dan 14,6mm. sedangkan pada pengujian antibakteri sabun kertas dapat formula 3 mengalami penurunan konsentrasi yakni berturut-turut 13,6 mm dan 9,8mm.
NANOEMULSION-BASED MOUTHWASH OF ETHYL ACETATE FRACTION OF SERAI WANGI STALK: FORMULATION, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY TEST Desy Ayu Irma Permatasari; Weri Veranita; Novalisa Nindhi Soraya; Eva Kholifah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.908

Abstract

Serai wangi or citronella (Cymbopogon nardus L.) has long been used in Indonesia as a component of traditional medicine. A recent study aimed to determine the antibacterial activity of the most active fraction of Citronella stalk extract and to formulate it  into a nanoemulsion mouthwash. Fractionation of the ethanolic extract was carried out using liquid-liquid extraction, and it was found that the ethyl acetate fraction (EAF) was the most active. This fraction was then varied at concentrations of 25%, 12.5%, 6.25%, 3.125%, 1.5625%, and 0.78125% for the antibacterial activity test using the disc diffusion test method. To determine the potency of microbial activity, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated. Subsequently, the ethyl acetate fraction was formulated into a nanoemulsion and characterized by measuring the transmittance percentage, droplet size, and polydispersity index (pdI) using a particle size analyzer. The results showed that the ethyl acetate fraction at a concentration of 25% obtained an inhibition zone diameter of 10.67 mm. MIC and MBC values ??were obtained at a fraction concentration of 6.25%. In addition, characterization of formulae exhibited particle size and pdI as follow 101.6 nm and 0.681 (Formula I); 84.1 nm and 0.609 (Formula II); 108.3 nm and 0.527 (Formula III).  Keywords:  Citronella stalk; fractionation; Streptococcus mutans; nano-emulsion; mouth wash
Formulasi dan uji aktivitas antioksidan sediaan hand body cream ekstrak kulit pisang emas menggunakan metode FRAP Ayuningsih, Qurotha; Septiarini, Anita Dwi; Veranita, Weri
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 7 No. 2 (2023): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v7i2.9979

Abstract

ABSTRACT Antioxidants are chemical compounds that, in certain amounts, can reduce or slow down damage caused by free radical oxidation processes. The content of compounds that have the potential as antioxidants is golden banana skin (Musa acuminata). This study aims to find out whether golden banana peel extract can be formulated into hand and body cream, whether the hand and body cream formulation of golden banana peel extract meets the requirements for good preparation evaluation, and whether the formulation of hand and body cream preparation with golden banana peel extract has antioxidant activity by the FRAP method. This research is a laboratory experimental research conducted by collecting and identifying plant materials and simplicia characteristics, making extracts, testing the correct antioxidant levels in the dosage formulations, and conducting antioxidant activity tests for hand and body cream preparations of golden banana peel extract using the FRAP method. The test results of the golden banana peel (Musa acuminata) can be formulated into hand and body cream preparations, with the best results in formulation 5, which consists of 3% extract with an average antioxidant activity value of 86.118 mgAAE/gram, which indicates the formulation of hand and body cream extract preparations. Mas banana peel has antioxidant activity with the FRAP method. The formulation of hand and body cream preparations with golden banana peel extract can meet the evaluation requirements for good hand and body cream preparations.   Keywords: Antioxidants, Golden Banana Peel, Hand and Body Cream   ABSTRAK Antioksidan adalah senyawa kimia yang dalam jumlah tertentu dapat mengurangi/ memperlambat kerusakan akibat proses oksidasi radikal bebas. Kandungan senyawa yang berpotensi sebagai antioksidan yaitu kulit pisang emas (Musa acuminata). Penelitian ini bertujuan untuk mengetahui apakah kulit pisang emas dapat diformulasikan menjadi hand and body cream, untuk mengetahui apakah formulasi sediaan hand and body cream ekstrak kulit pisang emas memenuhi syarat evaluasi sediaan yang baik serta mengetahui apakah formulasi sediaan hand and body cream ekstrak kulit pisang emas memiliki aktivitas antioksidan dengan metode FRAP. Penelitian ini merupakan penelitian eksperimen laboratorium dengan melakukan pengumpulan serta identifikasi bahan tumbuhan, karakteristik simplisia, pembuatan ekstrak, pengujian kadar antioksidan yang tepat dalam formulasi sediaan serta melakukan uji aktivitas antioksidan sediaan hand and body cream ekstrak kulit pisang emas menggunakan metode FRAP. Hasil pengujian kulit pisang emas (Musa acuminata) dapat diformulasikan menjadi sediaan hand and body cream dengan hasil terbaik pada formulasi 5 yang terdiri dari 3% ekstrak dengan nilai rata-rata aktivitas antioksidan sebesar 86,118 mgAAE/gram yang menandakan Formulasi sediaan hand and body cream ekstrak kulit pisang mas memiliki aktivitas antioksidan dengan metode FRAP. Formulasi sediaan hand and body cream ekstrak kulit pisang emas dapat memenuhi syarat evaluasi sediaan hand and body cream yang baik.   Kata kunci: Antioksidan, Kulit Pisang Emas, Hand and Body Cream
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BATANG SERAI WANGI (Cymbopogon nardus L) DENGAN METODE DPPH (2,2-diphenyl-1-picrylhydrazyl) Chairina, Nurvita; Ayu Irma Permatasari, Desy; Veranita, Weri
JURNAL FARMASI DAN KESEHATAN INDONESIA Vol. 3 No. 2 (2023): Jurnal Farmasi dan Kesehatan Indonesia
Publisher : Universitas Kristen Immanuel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61179/jfki.v3i2.376

Abstract

Serai wangi (Cymbopogon nardus L) merupakan tanaman yang cukup melimpah di Indonesia. Serai wangi (Cymbopogon nardus L) mengandung antioksidan flavonoid, dan senyawa fenolik seperti luteolin, glikosida, quercetin, kaempferol, elimicin, catecol, asam klorogenat, asam caffeic yang berkhasiat obat. Tujuan dari penelitian ini adalah untuk mengetahui nilai IC50 ekstrak batang serai wangi (Cymbopogon nardus L) dengan metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Ekstraksi batang serai wangi (Cymbopogon nardus L) dilakukan dengan metode maserasi dengan menggunakan pelarut etanol 96%. Uji aktivitas antioksidan ekstrak etanol batang serai wangi (Cymbopogon nardus L) dengan metode DPPH ((2,2-diphenyl-1-picrylhydrazyl) dibuat dalam berbagai konsentrasi. Penelitian ini menunjukan bahwa aktivitas antioksidan batang serai wangi dengan nilai IC50 adalah 919,52 ppm.
Formulasi Sediaan Deodoran Spray dari Kombinasi Minyak Atsiri Kulit Jeruk Kalamansi (Citrofortunella microcarpa) dan Ekstrak Teh Hijau (Camellia sinensis L) serta Uji Aktivitas Antibakteri Weri Veranita; Agung Eru Wibowo; Rachmaniar Rachmat
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.452

Abstract

Penggunaan sabun dan air sebagai pencuci badan pada waktu mandi relatif kurang efektif untuk mencegah bau badan. Sehingga dapat dilakukan beberapa alternatif tindakan lain, seperti menggunakan sediaan kosmetik anti bau badan (deodorant). Berdasarkan hasil penelitian dari 90% populasi di dunia ini telah menggunakan deodorant untuk mengontrol keringat dan bau di ketiak. Jeruk kalamansi (Citrusfortunela microcarpa) dipercaya dapat menghilangkan bau badan karena memiliki kandungan vitamin C dan flavonoid yang berperan sebagai antioksidan serta antibakteri. Sedangkan kandungan astringent alami pada teh hijau (Camellia sinensis L) dapat mengecilkan pori yang terbuka sehingga mengurangi produksi keringat. Pada penelitian ini dilakukan formulasi deodoran antiperspiran spray dari kombinasi minyak atsiri kulit jeruk kalamansi dan ekstrak teh hijau dengan tiga formula dengan perbandingan 1:1 yaitu formula 1 dengan perbandingan konsentrasi 1,5%:1,5% Formula 2 dengan perbandingan konsentrasi 0,75%:0,75% dan Formula 3 dengan perbandingan konsentrasi 0,375%:0,375%. Pengujian yang dilakukan meliputi pengujian antibakteri terhadap bakteri Pseuodomonas aureugenisa dan Staphylococcus epidermidis, uji iritasi, uji stabilitas dan uji antiperspiran dengan metode gravimetri. Hasil uji menunjukkan bahwa pengujian antibakteri memberikan diameter hambat tertinggi sebesar 17,3mm dan 20mm yaitu pada formulasi 1 masuk dalam kategori kuat. sedangkan pengujian antiperspiran dengan pada formula 1 mengurangi produksi keringat dengan hasil tertinggi sebanyak 9%. Dari hasil pengujian anti iritasi di dapat hasil negatif yang mana menunjukkan tidak terjadi iritasi sehingga aman untuk digunakan
Co-Authors Agung Eru Wibowo Agung Eru Wibowo Ana Yuliana Anik Sulistiyanti Aydi, Danisa Putri Ayu Irma Permatasari, Desy Ayuningsih, Qurotha Chairina, Nurvita Desy Ayu Irma Permatasari Eva Kholifah Fajariyani, Ayu Ferry Effendi Herawan, Annisa Aliffiah Kusumaningtyas Siwi Artini Listyani, Tiara Ajeng Mariyana, Tyssa Musta'in, Musta'in Ningsih, Wahyuni Novalisa Nindhi Soraya Nusanty, Oci Etri Puji Sari Rachmaniar Rachmat Rizqi Pratiwi, Retno Inten Septiarini, Anita Dwi Setianingsih Setianingsih, Setianingsih Siti Nurbaya Siva Fauziah, Siva Tatiana Siska Wardani