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Ahmad Shafwan S. Pulungan
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Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan Jl. Willem Iskandar Psr V Medan Estate, Sumatera Utara
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JBIO: jurnal biosains (the journal of biosciences)
Published by Universitas Negeri Medan
ISSN : 24431230     EISSN : 24606804     DOI : https://doi.org/10.24114/jbio.v6i1
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology
Jurnal Biosains (JBIO) features works of exceptional significance, originality, and relevance in all areas of biological science, from molecules to ecosystems, (ie genetic, microbiology, ecology, biosystematic, biostatistic) including works at the interface of other disciplines, such as chemistry, medicine,physic and mathematics. We also welcome data-driven meta-research articles that evaluate and aim to improve the standards of research in the life sciences and beyond. Our audience is the international scientific community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol. 11 No. 2 (2025): JURNAL BIOSAINS" : 5 Documents clear
Formulation of Java Acid Leaves (Tamarindus indica L.) Etanol Extract Salep Devices With Absorption, Hydrocarbon, Water Solution and Water Washable Basis (O/W Emulsion) Kurniaty, Rina; Sukma Ratmelya, Dara
JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i2.66781

Abstract

Tamarind leaves have flavonoid, tannin and saponin compounds, which can be used as antibacterials. Research has been conducted on the formulation of ointment preparations from tamarind leaf ethanol extract (Tamarindus indica L.) using a variety of ointment bases, namely absorption, hydrocarbon, water soluble and washable with water (O/W emulsions). This study aims to determine the physical stability and the appropriate type of ointment base of tamarind leaf ethanol extract ointment preparation. The extraction process in this study used maceration method with 70% ethanol solvent. The formalized preparation was evaluated for physical stability for 10 days at 4°C and 25°C alternately every 24 hours (1 cycle). The evaluation included organoleptic test, pH, homogeneity and spreadability. Absorption ointment made from ethanol extract of tamarind leaves is light brown in color, smells typical of tamarind, homogeneous, has a pH of 4 and has a spreadability of 5 cm. Hydrocarbon ointment is dark brown in color, smells typical of tamarind, homogeneous, has a pH of 3 and has a spreadability of 3.95 cm. Water soluble ointment with ethanol extract of tamarind leaves is dark brown in color, smells typical of tamarind, homogeneous, has a pH of 3 and has a spreadability of 5.3-5.5 cm. Water washable ointment (O/W emulsion) is light brown in color, smells typical of tamarind, homogeneous, has a pH of 4, and has a spreadability of 3.93 cm. Based on the test results in this study, it can be concluded that the formulation of ethanol leaf extract preparation.
Identifying Sibutramine in Slimming Herbs Sold Online Rina Kurniaty; Fachruniza, Yunda; Rahmayani, Nabila
JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i2.66791

Abstract

Obesity is defined as the presence of abnormal amounts of body fat and is a risk factor for diabetes and can increase the risk of hernias, varices and arthroses in the knees and feet. Consumption of slimming herbs is widely used to reduce this obesity. Slimming herbal products in their ingredients or compositions contain simplisia derived from medicinal plants and have pharmacological effects. According to the Minister of Health Regulation No. 007 of 2012 concerning the registration of traditional medicines, herbs circulating in the community must meet various requirements, one of which is that they must not contain drug chemicals, narcotics or psychotropic substances and other materials that based on health considerations and research can endanger health. Sibutramine is a weight loss drug that is often used, belongs to the class of hard drugs and can only be used based on a doctor's prescription because it can increase blood pressure. The identification of sibutramine in this study was carried out qualitatively using thin layer chromatography (TLC) method, to determine the presence or absence of the addition of drug chemicals in slimming herbs sold online. The mobile phase used was methanol (p): chloroform (p) (4:1) solvent with silica GF 254 stationary phase. The results of the study showed that two of the five slimming herbs sold online contained sibutramine with the Rf value of herbal medicine A = 0.86 and herbal medicine B = 0.91.
The Effectiveness of Aloe Vera Extract as A Natural Ingredient in Reducing Hair Loss nurmagrianty, khandika cece; Agustin , Eny Widhia
JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i2.67996

Abstract

Hair loss is a common condition affecting many individuals, particularly teenagers and women who wear the hijab. Aloe vera contains various bioactive compounds, including vitamins, proteolytic enzymes, and amino acids, which are known to nourish the scalp and stimulate hair growth. This study aims to evaluate the effectiveness of Aloe vera extract in different types of hair care formulations, such as shampoos, hair tonics, serums, and pomades, for treating hair loss. A qualitative descriptive literature review was conducted by analyzing 30 relevant national and international scientific articles published between 2016 and 2025. The findings indicate that Aloe vera has the potential to reduce hair loss, promote hair growth, and support scalp health. Furthermore, the combination of Aloe vera with other herbal ingredients, such as candlenut, celery, and lime, may enhance its efficacy. Products based on Aloe vera are also reported to have good physical stability, be safe for use, and be compatible with various scalp types. The study concludes that Aloe vera is a promising natural ingredient for the development of safe, effective, and sustainable herbal hair care products.
Optimization and Evaluation of Noni Leaf Skin Softening Lotion Preparation (Morinda Citrifolia L.) barus, bunga rimta; Ilsanna Surbakti, Christica; Salman, Salman
JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i2.68012

Abstract

The premature aging process is usually characterized by visible wrinkles or wrinkles on the face, dry and rough skin, age spots and decreased skin elasticity. Noni leaves (Morinda citrifolia L.) are one type of herbal plant that can potentially act as an antioxidant. The purpose of this study was to see Optimizing the Formulation of Lotion Preparations and Evaluating the Physical Properties of Lotion Preparations. Noni leaves were macerated with 96% ethanol solvent and then rotary with an evaporator. Hand and body lotion preparations were made by adding ethanol extract of noni leaves with several concentrations of 2.5% (F1), 5% (F2), and 7.5% (F3) to the base of hand and body lotion. As a blank (F0) the base of hand and body lotion without ethanol extract of noni leaves. Testing on the preparation was an evaluation of stability for 4 weeks at room temperature (odor, color, pH, emulsion type, homogeneity), irritation test and anti- aging skin activity test using a skin analyzer on hand skin. The parameters measured included water content, pore size, number of blemishes and number of wrinkles. Treatment was carried out using hand and body lotion every day for 4 weeks. Ethanol extract concentrations of 2.5%, 5% and 7.5% were homogeneous preparations with an oil-in-water emulsion type, pH 6.3-6.8, stable in storage for 4 weeks, and did not irritate the skin. Anti- aging skin hand and body lotion preparations containing ethanol extract of noni leaves can increase water content, reduce pore size, reduce the number of blemishes, reduce the number of wrinkles on the skin of the back of the hand and are stable in storage for 4 weeks. Hand and body lotion preparations with ethanol extract at a concentration of 7.5% had better skin antiaging activity compared to concentrations of 2.5%, 5% and blank.
Antioxidant Activity Test of Extract And Fractions of Red Guava (Psidium guajava L.) Peel and Fruit Monica; Rohmana, Vivin Marwiyati; Pratama, Kharisma Jayak
JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i2.68054

Abstract

Red guava (Psidium guajava L.) contains natural antioxidants that help neutralize free radicals originating from radiation, pollution, and harmful chemicals. This study aimed to identify secondary metabolites and determine the IC₅₀ values of ethanol extract and various fractions of red guava peel and fruit. Four solvents were used ethanol extract, ethyl acetate fraction, n-hexane fraction, and water fraction. Each sample was tested at concentrations of 20, 40, 60, 80, and 100 ppm. Vitamin C, at concentrations of 2, 4, 6, 8 and 10 ppm, served as a positive control. Antioxidant activity was evaluated using the DPPH method with a UV-Vis spectrophotometer at a wavelength of 516 nm and an incubation time of 30 minutes. Phytochemical screening showed that all extracts contained alkaloids, flavonoids, and tannins. The IC₅₀ values obtained were: ethanol extract peel 62,4719 ppm, ethanol extract fruit 44,0035 ppm, ethyl acetate fraction peel 56,7955 ppm, ethyl acetate fraction fruit 46,4394 ppm, n-hexane fraction peel 113,9311 ppm, n-hexane fraction fruit 114,4767 ppm, water fraction peel 104,0284 ppm, and water fraction fruit 76,5801 ppm.

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