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INDONESIA
Jurnal Kedokteran Syiah Kuala
Published by Universitas Syiah Kuala
ISSN : 14421026     EISSN : 25500112     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 545 Documents
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Uji in Vivo Ekstrak Etanol Daun Sambung Nyawa (Gynura procumbens) Terhadap Penurunan Kadar Gula Darah Mencit (Mus musculus) Jantan Strain Swiss Webster Diabetes Mellitus Sofia Sofia; Rinidar Rinidar; Mariana Mariana
Jurnal Kedokteran Syiah Kuala Vol 11, No 3 (2011): Volume 11 Nomor 3 Desember 2011
Publisher : Universitas Syiah Kuala

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Abstrak. Diabetes mellitus merupakan penyakit dengan gangguan metabolisme karbohidrat yang ditandai  kadar glukosa darah yang tinggi (hiperglikemi) dan adanya glukosa dalam urin (glukosuria). Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak etanol daun sambung nyawa (Gynura procumbens) dalam menurunkan kadar gula darah mencit (Mus musculus) jantan strain Swiss Webster yang di induksi aloksan. Desain penelitian ini adalah Rancangan Acak Lengkap (RAL) dengan 5 (lima) perlakuan (N = 25). Ekstrak etanol daun sambung nyawa diberikan secara per oral dengan dosis P1 (100 mg/kgBB), P2 (150 mg/kgBB) dan P3 (200 mg/kgBB). Kelompok kontrol positif (KP) diberi glibenklamida 10 mg/kgBB dan kelompok kontrol negatif (KN) diberi akuades 0,2 cc. Analisis Varian (ANAVA) satu arah menunjukkan bahwa terdapat perbedaan yang nyata antara kelima kelompok perlakuan terhadap penurunan kadar gula darah (p0,05). Uji LSD menjelaskan bahwa pemberian ekstrak etanol daun sambung nyawa dosis 150 mg/kgBB (P2) dan 200 mg/kgBB (P3) menunjukkan pengaruh yang bermakna terhadap penurunan gula darah mencit diabetes mellitus yang di induksi aloksan sedangkan dosis 100 mg/kgBB (P1) tidak berpengaruh. Kesimpulan penelitian ini adalah dosis efektif dalam penurunan peningkatan kadar gula darah pada Mus Musculus strain Swiss-Webster adalah 200 mg/kgBB. Abstract. Diabetes Mellitus is a disease of carbohydrate metabolism disorder characterized by high blood glucose levels (hyperglycemia) and presence of glucose in the urine (glucosuria). The aims of this study was to determine the effect of ethanol extract of Gynura procumbens leaves in lowering blood glucose levels of Mus musculus Swiss Webster- strained induced alloxan. This study conducted using a laboratory experimental design of completely randomized design (CRD), which divided into 5(five) treatment groups (N=25). Ethanol extract of Gynura procumbens leaves were administered orally with doses of P1 (100 mg/kg BW), P2 (150 mg/kg BW) and P3 (200 mg/kg BW). Positive control group (CP) were given 10 mg/kg BW of glibenklamida and negative control groups (CN) were given 0.2 cc distilled water. One-way ANOVA showed that decreasing blood glucose levels were significantly different among the five treatment groups (p0.05). LSD test confirmed that P2 (150 mg/kg BW) and P3 (200 mg/kg BW) were significantly different in lowering blood glucose levels (p0.05) whether P1 (100 mg/kg BW) was not.  It concluded that the most effective dose in lowering elevated levels of blood glucose was 200 mg/kgBW.
The Effect of Administration of Lycopene on Interleukin 8 Levels and Hospitalization Time of Patients with Chronic Obstructive Pulmonary Disease Exacerbations Yusup Subagio Sutanto; Diana Kurniasari Sagita; Suradi Suradi; Hendra Kurniawan
Jurnal Kedokteran Syiah Kuala Vol 19, No 1 (2019): Volume 19 Nomor 1 April 2019
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v19i1.17404

Abstract

Background: Exacerbated chronic obstructive pulmonary disease is an acute condition, characterized by persistent air flow limitations, related to the excessive chronic inflammatory response in the airways and lung parenchyma caused by exposure to harmful gases or particles. Increased airway inflammation during exacerbations leads to increased levels of IL-8 and the risk of hospitalization. Lycopene is a carotenoid which has a positive effect on the respiratory system. The purpose of this study was to determine the effect of administration  lycopene to IL-8 levels and hospitalization time of patients with COPD disease exacerbations.Methods: The  experimental test with pretest and posttest  design for 30 patients with COPD exacerbations in Dr. Moewardi Surakarta Hospital and Dr. Soehadi Prijonegoro Sragen Hospital was conducted from February to March 2018. Samples were taken by consecutive sampling divided into two groups including the treatment group receiving standard therapy and lycopene 1x10 mg / day during treatment and the control group only receiving standard therapy. IL-8 levels  and hospitalization time of patients with COPD disease exacerbations  were measured.Results: There were significant differences between the treatment group compared to the control group for a decrease in IL-8 (p = 0.029) and a decrease in hospitalization time (p = 0,000).Conclusion: The administration of lycopene 1x10 mg / day significantly reduce IL-8 levels and hospitalization time of patient with COPD exacerbations. 
A CASE OF SILENT SPONTANEOUS UTERINE RUPTURE AT 27-28 WEEKS OF GESTATION, TWO PRIOR C- SECTIONS AND HISTORY OF UTERINE RUPTURE Lutfi, M.D.; Tengku Puspa Dewi
Jurnal Kedokteran Syiah Kuala Vol 18, No 1 (2018): Volume 18 Nomor 1 April 2018
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v18i1.11213

Abstract

Introduction.Silent spontaneous rupture of the uterus at the second trimester of gestation was very rare. In this case was accompaniedby extrusion of an intact amniotic sac and normal fetal heart rate base line. Silent uterine rupture can be very difficult to diagnose, as the clinical features of uterine rupture, including abdominal pain, vaginal bleeding, maternal hypovolemic shock or hemorrhage, may be absent.Very few cases have been reported in literature.CasePresentation.Wereport a case of silent spontaneous uterine ruptureat 27-28 Weeks of Gestation.Patient had history of two prior cesarean sections with the last C-sections has uterine rupture. The residents were misdiagnosis silent spontaneous rupture with condition of dyspepsia. She underwent cesarean subtotal hysterectomy and deliveredalive infant. She had a good postoperative recovery and was discharged on postoperative day 3. Conclusion.Silent spontaneous rupture of the uterus at second trimester of gestation with extrusion of an intact amniotic sac is rare.For this case even there were no sign of acute abdomen and shock but only sign of dyspepsia. We have to think about the risk of Rupture uterine imminens. A high index of suspicion and good imagingduring pregnancy are important in making this diagnosis. Keywords: uterine rupture, dyspepsia, cesareanhysterectomy
MALNUTRISI PADA DEMENSIA Rachmi Kurniawati
Jurnal Kedokteran Syiah Kuala Vol 13, No 2 (2013): Volume 13 Nomor 2 Agustus 2013
Publisher : Universitas Syiah Kuala

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Abstrak. Pasien demensia sering mengalami malnutrisi saat dirawat di rumah atau di fasilitas rawatan jangka panjang karena mengalami kesulitan koordinasi, tidak mampu mengenali makanan dan ketergantungan pada orang lain dalam perawatan sehari-hari. Hal tersebut berhubungan dengan progresifitas demensia sehingga asupan makronutrien dan mikronutrien menjadi tidak memadai. Tim medis harus mengidentifikasi penyebab penurunan berat badan dengan cara yang sistematis. Pencegahan dapat dilakukan dengan memperhatikan asupan makanan, cairan dan serat yang cukup. Penanganan malnutrisi pada demensia memerlukan evaluasi dan penatalaksanaan secara tepat, bila diperlukan dokter dapat merujuk pasien tersebut kepada ahli gizi.Abstract. Patients with dementia often suffer from malnutrition while treated at home or in long-term care facilities due to difficulty of coordination, unable to recognize food and rely on others in daily care. It is corralated with the progressivity of dementia which results in macronutrient and micronutrient intake became inadequate. Medical team has to identify the cause of weight loss in a systematic way. Prevention can be done by caring adequate food, fluid and fiber. Treatment of malnutrition in dementia requires proper evaluation, if necessary doctors may refer the patient to a nutritionist.
Keselamatan dan kesebatan kerja laboratorium kesebatan Liza Salawati
Jurnal Kedokteran Syiah Kuala Vol 9, No 3 (2009): Volume 9 Nomor 3 Desember 2009
Publisher : Universitas Syiah Kuala

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Abstrak.   Pelayanan laboratorium kesehatan merupakan pelayanan   yang  perlu memperbatikan  secara khusus mengenai keselamatan dan kesehatan kerja oleh karena mempunyai risiko tinggi untuk terjadinya kecelakaan kerja dan penyakit akibat kerja. Pekerja di laboratorium kesehatan harus selalu mempelajari  dan mendeteksi  setiap kemungk:inan timbul risiko kecelakaan kerja  clan penyakit  akibat kerja, harus senantiasa meningkatkan kesadaran dan kedisiplinan dalam menta'ati peraturan dengan demikian dapat meminimalkan risiko yang akan terjadi. (JKS 2009; 3:151-16') Kata kunci: Keselamatan dan kesehatan kerja, kecelakaan kerja, penyakit akibat kerja, laboratorium kesehatan                                      Abstract.The services of health laboratory are services that need to pay attention especially on the occupational health and safety due to the high risk that it could lead. Health Laboratory  workers must always analyze and detect any potential risk of accident at work and occupational diseases, ones should raise awareness and discipline in following the laboratory manuals to reduce any potential risks. (JKS 2009; 3:157-16' Keywords:   Occupational health and safety, accident at work, occupational diseases, health laboratory
EVALUASI PARTISIPASI PENDIDIKAN KEBENCANAAN PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS SYIAH KUALA (Setelah Mengikuti Blok Disaster Management) Ilham M; Mulyadi Mulyadi; Imran Imran; Syahrul Syahrul; Mudatsir Mudatsir; Jasa ZK
Jurnal Kedokteran Syiah Kuala Vol 16, No 3 (2016): Volume 16 Nomor 3 Desember 2016
Publisher : Universitas Syiah Kuala

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Ketuban Pecah Dini dan Tatalaksananya, sebuah tinjauan kasu Raipati Fahlevi FAHLEVI
Jurnal Kedokteran Syiah Kuala Vol 19, No 3 (2019): Volume 19 Nomor 3 Desember 2019
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v19i3.10907

Abstract

Ketuban Pecah Dini (KPD) atau Premature rupture of Membranes (PROM) merupakan pecahnya ketuban yang terjadi sebelum proses persalinan. Ketuban pecah dini terjadi sekitar 1% dari seluruh kehamilan. Ketuban pecah dini menyebabkan terjadinya 1/3 persalinan preterm dan merupakan penyebab 18%-20% dari morbiditas dan mortalitas perinatal.Dalam laporan kasus ini kami melaporkan seorang ibu hamil berusia 35 tahun, gravida 3, hamil aterm dengan ketuban pecah dini, keluhan keluar air dari jalan lahir dan belum inpartu. Laporan kasus ini bertujuan untuk meningkatkan kualitas diagnosa dini serta penatalaksanaan ketuban pecah dini untuk mengurangi risiko bagi ibu dan janin.
Seorang Penderita Fistel Empiema Toraks Dengan Colostomy Bag Isa Ansori; Soedarsono Soedarsono
Jurnal Kedokteran Syiah Kuala Vol 6, No 1 (2006): Volume 6 Nomor 1 April 2006
Publisher : Universitas Syiah Kuala

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Abstr  ak,  Laki,  26  tahun  MRS  dengan   keluhan  keluar  cairan  dari  lubang  bekas  pernasangan   toraks drain  sebelah   kanan  sejak  satu  tahun  yang  Ialu berwarna  coklai  kekuningan   keruh  terus  rnenerus,   foto toraks  PA/lateral    kanan   perselubungan   homogen  di hernitoraks  kanan  bawah,  BT A  positif  dua  (+ 2), biakan  I kultur  cairan  empierna   didapatkan    Acinetobacter   spp.,seramoeba    dengan   uji semi  kuantitatif hasil  positif.  Dilakukan   pasang  "window    fisrel"   atau  "open  drainage"   sebagai   "drainage"  cairan  pus yang   sudah    diencerkan    dengan   rnernasukkau    larutan   PZ  dan   diinstilasi    clengan    antibiotik    serta pemasangan   "colostomy bag" sebagai   penarnpung   cairan pus yang mengalir  keluar,   (.!KS 2006,·J:5-12) Kata   Kunci:    Empyerna  kronis, drainase  WSD. Abstract.  Male,  26 years old ran into a doctor  with  a complaint  that a kind  of fluid came  out  from the right  side  of the thoracic  drain hole.  The  fluid had  turbid yellowish  brown  that came  out continuously. This   condition    happened   for  about  one  year.  From  the  chest   radiograph    PA/on   the  right   lateral, hemithorax    homogeneous    veil  in  the  lower  right,   AFB   positive    (+ +),  culture   of  empyerna   fluid obtained  Acinetobacter  spp,  seramoeba   with  semi-quantitative    test  produced   a  positive    result.   The "window   fistel"  or "open  drainage"  as "drainage"  was perfomed  with  pus  that  diluted   by putting   into the PZ solution  and instilated    with antibiotics  and  the installation   of "colostomy   bag" as a container   of fluid  which  will  flowed out.(JKS 2006;1:5-12) Key wonts:  Chronic  Empyerna,  WSD
PENYAKIT AKIBAT KERJA DAN PENCEGAHAN Liza Salawati
Jurnal Kedokteran Syiah Kuala Vol 15, No 2 (2015): Volume 15 Nomor 2 Agustus 2015
Publisher : Universitas Syiah Kuala

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Abstrak. Sumber daya manusia sebagai tenaga kerja dalam  perusahaan tidak terlepas dari adanya masalah yang berkaitan dengan Keselamatan dan Kesehatan Kerja (K3). Kejadian Penyakit Akibat Kerja (PAK) dan Kecelakaan Akibat Kerja (KAK) di Indonesia tahun 2011 tercatat 96.314 kasus dengan korban meninggal 2.144 orang dan cacat 42 orang. Pada tahun 2012 kasus PAK dan KAK meningkat menjadi 103.000 kasus. Hal ini menunjukkan bahwa penerapan Sistem Manajemen Keselamatan dan Kesehatan Kerja (SMK3) di Indonesia belum berjalan dengan baik.Masalah K3 tidak hanya menjadi tanggung jawab pemerintah tetapi tanggung jawab dari semua pihak terutama pengusaha, tenaga kerja dan masyarakat. Pelaksanaan SMK3 adalah salah satu bentuk upaya untuk menciptakan tempat kerja yang aman, sehat, bebas dari pencemaran lingkungan sehingga dapat mengurangi dan atau bebas dari PAK dan KAK, pada akhirnya dapat meningkatkan efisiensi dan produktivitas kerja. Abstract. Human resources as labor in the company is not separated from the problems associated with the Occupational Health and Safety (OHS). Occupational disease and occupational accident  in Indonesia on 2011 recorded 96 314 cases with 2,144 deaths and disabled people 42 people. In 2012 the case of occupational disease and occupational accident increased to 103,000 cases. This indicates that the application of the occupational safety and health management system in Indonesia has not been going well. OHS problem is not just the responsibility of the government but the responsibility of all parties, especially employers, workers and the public. The occupational safety and health management system  implementation is one of the efforts to create a workplace that is safe, healthy, free from environmental pollution so as to reduce and or free of the occupational disease and occupational accident  , can ultimately improve efficiency and productivity. 
Faktor-Faktor yang Mempengaruhi Terjadinya Infeksi Kusta Mudatsir Mudatsir
Jurnal Kedokteran Syiah Kuala Vol 10, No 2 (2010): Volume 10 Nomor 2 Agustus 2010
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Abstrak.  Program pemberantasan kusta di dunia telah berjalan Jebih dari 20 tahun terakhir, namun kasus insiden kusta baru tidak menurun. Dengan kata lain penularan penyakit kusta masih terus terjadi di rnana- mana. Sampai dengan saat ini manusia masih  diyakini  sebagai sumber penularan Mycobacterium leprae yang utama, terutama pada penderita kasus tipe lepromatosa yang sangat infeksius. Banyak    faktor yang mempengaruhi  terjadinya  penularan penyakit  kusta seperti  lamanya kontak,  keeratan  hubungan,  status imunitas, status gizi, sosial ekonomi, genetik, hygiene  dan sanitasi lingkungan, serta mempunyai beberapa cara penularan. Cara penularan yang utama adalah melalui kontak dengan penderita kusta (kontak antar kulit, kontak intim, kontak berulang-ulang). Mycobacterium leprae dari penderita kusta terutama penderiita kusta tipe MB masuk ke dalam tubuh seseorang melalui saluran pemafasan. (JKS2010;2:99-104)Kata Kunci: Mycobacterium leprae, kusta, inhalasi, kontakAbstract.   The program to eradicate leprosy in the world has been taken for the last 20 years, but the incidence of new leprosy cases do not. decline yet. In other words, the transmission of leprosy is still occurring everywhere.  Up  today, humans are still  believed to be a  major source infection  of  Leprae Mycobacterium, particularly on the patients with lepromatous type of cases that are· extremely infectious. There-are many factors that influence the occurrence of leprosy transmission, such as the length of contact, closeness of relationship, immune status, nutritional status, socio-economic, genetic, hygiene and sanitation environment. There are several modes of leprosy transmission. The main mode of transmission is through contact with people that have leprosy (contact between the skin, intimate contacts, contacts repeatedly). Leprae  Mycobacterium  from  leprosy patients  especially patients  with MB  leprosy  type  would  infect someone through the respiratory tract. (JKS 2010;2:99-104)Keywords: Leprae Mycobacterium, leprosy, inhalation, contact

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