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Journal of Biomedical and Techno Nanomaterials
Published by Yayasan Adra Karima Hubbi
ISSN : 30481120     EISSN : 30481155     DOI : 10.70177/jbtn
Core Subject : Science,
Biochemistry, Genetics & Molecular Biology
Journal of Biomedical and Techno Nanomaterials is an international forum for the publication of peer-reviewed integrative review articles, special thematic issues, reflections or comments on previous research or new research directions, interviews, replications, and intervention articles - all pertaining to the research fields of medicine, pharmaceuticals, biomaterials, biotechnology, diagnosis and prevention of diseases, biomedical devices, bioinformatics, and all other related fields of biomedical and life sciences. All publications provide breadth of coverage appropriate to a wide readership in Biomedical and Techno Nanomaterials research depth to inform specialists in that area. We feel that the rapidly growing Journal of Biomedical and Techno Nanomaterials community is looking for a journal with this profile that we can achieve together. Submitted papers must be written in English for initial review stage by editors and further review process by minimum two international reviewers.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 7 Documents
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Search results for , issue "vol. 3 no. 2 (2026)" : 7 Documents clear
PHARMACEUTICAL NANOTECHNOLOGY FOR IMPROVING BIOAVAILABILITY AND THERAPEUTIC EFFICACY Fatima Ahmed; Ali Omar; Muntasir Muntasir
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3211

Abstract

Pharmaceutical nanotechnology has emerged as a promising approach to enhance the bioavailability and therapeutic efficacy of drugs. Many drugs suffer from poor solubility, limited absorption, and rapid metabolism, leading to suboptimal therapeutic outcomes. Nanotechnology-based drug delivery systems offer solutions to these challenges by improving the stability, solubility, and controlled release of pharmaceuticals. This study explores the use of nanotechnology in the design and development of drug delivery systems aimed at enhancing bioavailability and optimizing therapeutic efficacy. The primary objective is to evaluate the effectiveness of various nanocarriers, including liposomes, dendrimers, and polymeric nanoparticles, in improving drug solubility and ensuring targeted delivery. The research employs in vitro and in vivo models to assess drug release profiles, absorption rates, and pharmacokinetic properties. The results demonstrate that nanotechnology-based systems significantly improve drug bioavailability and extend therapeutic efficacy by providing controlled and sustained drug release, reducing side effects, and enhancing cellular uptake. In conclusion, pharmaceutical nanotechnology offers a powerful strategy to overcome the limitations of conventional drug delivery systems, providing a pathway for more effective treatments in various therapeutic areas.
CELL MATERIAL INTERACTIONS AT THE NANO-BIO INTERFACE: IMPLICATIONS FOR REGENERATIVE MEDICINE Ayesha Begum; Zahidul Islam; Shakib Ahmed
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3958

Abstract

Cell-material interactions at the nano-bio interface play a pivotal role in the success of regenerative medicine, as these interactions dictate cell behavior, differentiation, and tissue integration. The advent of nanotechnology has enabled the development of materials with tunable properties at the nanoscale, providing new opportunities for enhancing tissue regeneration and healing. Despite the significant progress in this field, understanding the molecular mechanisms underlying these interactions remains a challenge. This study investigates the relationship between cells and nanomaterials, focusing on the impact of surface properties, topography, and chemical composition of materials on cellular behavior. The primary objective is to assess how engineered nanomaterials influence cellular responses such as adhesion, migration, proliferation, and differentiation. Experimental methods, including cell culture on nanostructured substrates, surface characterization using atomic force microscopy (AFM), and gene expression analysis, were employed to evaluate these interactions. The results demonstrate that nanomaterials with specific surface characteristics significantly enhance cell adhesion and proliferation, promoting tissue growth and regeneration. In conclusion, the nano-bio interface offers promising opportunities for developing advanced biomaterials for regenerative medicine, with implications for improving the functionality and biocompatibility of tissue-engineered constructs.
NANOMATERIAL BASED ANTIMICROBIAL SYSTEMS FOR INFECTIOUS DISEASE PREVENTION Raymond Foster; Leon Gittens; Julian Browne
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3960

Abstract

Nanomaterials have gained significant attention as effective antimicrobial agents for combating infectious diseases due to their unique properties, including high surface area, small size, and enhanced interaction with microbial cells. Traditional antimicrobial therapies, such as antibiotics, have limitations, including the development of resistance, which has spurred the exploration of alternative strategies. This study investigates nanomaterial-based antimicrobial systems, focusing on their efficacy in preventing and treating infections caused by bacteria, fungi, and viruses. The primary aim is to evaluate the antimicrobial properties of various nanomaterials, such as silver nanoparticles, copper oxide nanoparticles, and graphene oxide, and to assess their potential applications in medical devices and surface coatings. The research employs in vitro methods, including disk diffusion assays, minimum inhibitory concentration (MIC) testing, and bacterial growth curve analysis, to evaluate the antimicrobial activity of these nanomaterials. The results show that nanomaterial-based systems exhibit significant antimicrobial activity, with silver nanoparticles demonstrating the highest efficacy in inhibiting bacterial growth, followed by copper oxide and graphene oxide. In conclusion, nanomaterial-based antimicrobial systems offer a promising alternative to traditional antimicrobial treatments, with the potential to address the growing challenge of antimicrobial resistance in infectious diseases.
NUCLEIC ACID AND PROTEIN-BASED NANOTHERAPEUTICS FOR PRECISION MEDICINE Adwoa Agyemang; Samuel Bediako; Kwame Mensah
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3961

Abstract

Nucleic acid and protein-based nanotherapeutics have emerged as revolutionary approaches in the field of precision medicine, offering highly targeted treatments for various diseases, including cancer, genetic disorders, and viral infections. Traditional therapies often face challenges such as off-target effects, limited bioavailability, and inadequate therapeutic outcomes. Nanotechnology, leveraging the unique properties of nucleic acids (DNA/RNA) and proteins encapsulated in nanomaterials, provides solutions to these limitations by enabling controlled drug release, targeted delivery, and enhanced therapeutic efficacy. This study explores the potential of nucleic acid and protein-based nanotherapeutics in precision medicine, focusing on their mechanisms, applications, and future prospects. The research employs in vitro and in vivo models to evaluate the delivery efficiency, biocompatibility, and therapeutic effectiveness of these nanotherapeutics. The results indicate that nucleic acid-based nanoparticles, such as siRNA and DNA, show significant efficacy in gene silencing and expression modulation, while protein-based nanocarriers demonstrate enhanced targeting of specific cells and tissues. In conclusion, nucleic acid and protein-based nanotherapeutics offer promising advances in precision medicine, providing a new paradigm for treating diseases with high specificity and reduced side effects.
NANOFABRICATION STRATEGIES FOR ARTIFICIAL CELLS, TISSUES, AND ORGANS Silva Fitri; Miku Fujita; Daiki Nishida
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.4073

Abstract

Nanofabrication techniques have emerged as pivotal tools in the creation of artificial cells, tissues, and organs, which hold the potential to revolutionize regenerative medicine and organ transplantation. The ability to precisely engineer materials at the nanoscale allows for the replication of biological structures, enabling the development of functional tissue replacements and therapeutic devices. Traditional methods in tissue engineering often face challenges in mimicking the complexity of natural tissues and organs, leading to suboptimal functionality and biocompatibility. This study investigates various nanofabrication strategies used in the development of artificial cells, tissues, and organs, with an emphasis on their applications in biomedical fields. The main objective of this research is to assess the effectiveness of different nanofabrication approaches, such as 3D printing, self-assembly, and nanolithography, in replicating the architecture and functionality of human tissues. In vitro and in vivo models are employed to evaluate the biocompatibility, structural integrity, and functional performance of fabricated constructs. The results indicate that nanofabricated systems show significant promise in replicating the mechanical, biochemical, and cellular properties of natural tissues. In conclusion, nanofabrication offers an innovative approach to the creation of functional artificial tissues and organs, which could significantly impact the future of medical treatments, particularly in tissue regeneration and transplantation.
ADVANCED NANOCARRIERS FOR CONTROLLED DRUG AND GENE DELIVERY IN CHRONIC DISEASES Ren Suzuki; Daiki Nishida; Nila Trisna Yulianti
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3585

Abstract

Chronic diseases such as cancer, cardiovascular diseases, and neurodegenerative disorders pose significant treatment challenges due to their complexity and resistance to conventional therapies. Nanocarriers, as advanced drug and gene delivery systems, offer a promising solution to address these challenges by providing controlled release, improved targeting, and enhanced therapeutic efficacy. The ability to design nanocarriers that are biocompatible, stable, and capable of precise targeting to diseased tissues holds potential for revolutionizing the treatment of chronic diseases. This study aims to explore the design, development, and evaluation of advanced nanocarriers for controlled drug and gene delivery in chronic diseases. The research focuses on evaluating the efficacy of various nanocarriers, including liposomes, dendrimers, and nanoparticles, in improving drug bioavailability, targeting precision, and therapeutic outcomes in chronic disease models. The research utilizes in vitro cell culture studies and in vivo animal models to assess the effectiveness of different nanocarriers. Characterization techniques, including dynamic light scattering (DLS), transmission electron microscopy (TEM), and drug release assays, are used to evaluate the properties and performance of the nanocarriers. The study demonstrates that advanced nanocarriers significantly improve drug delivery efficiency, reduce systemic toxicity, and enhance therapeutic outcomes in chronic disease models. Gene delivery using nanocarriers also shows promising results in terms of targeted therapy. Advanced nanocarriers are a promising tool for controlled drug and gene delivery, offering potential breakthroughs in the treatment of chronic diseases by improving precision and minimizing side effects.
BIODEGRADABLE NANOMATERIALS FOR TISSUE ENGINEERING AND REGENERATIVE MEDICINE APPLICATIONS Fitriani Fitriani; Khalid Al Ansari; Sarah Al Sabih
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3642

Abstract

The field of tissue engineering and regenerative medicine has seen significant advancements with the use of nanomaterials, particularly biodegradable nanomaterials, which offer promising solutions for tissue regeneration and repair. These materials, due to their biocompatibility, biodegradability, and ability to mimic the extracellular matrix, play a crucial role in supporting cell growth, tissue development, and healing processes. Despite these promising properties, challenges remain regarding the optimization of nanomaterial performance, including controlled degradation rates and tissue-specific responses. This study aims to explore the potential of biodegradable nanomaterials in tissue engineering and regenerative medicine, focusing on their applications, properties, and functional enhancements through design optimization. The research aims to evaluate the efficacy of these nanomaterials in promoting tissue regeneration in various models, including bone, cartilage, and soft tissues. The study involves the synthesis and characterization of biodegradable nanomaterials, including nanofibers, nanoparticles, and hydrogels. In vitro cell culture assays and in vivo animal models are used to assess cell viability, proliferation, differentiation, and tissue regeneration potential. The study demonstrates that biodegradable nanomaterials significantly promote cell proliferation and differentiation, accelerating tissue repair and regeneration in all tested models. Controlled degradation rates of the nanomaterials contributed to sustained cell support and tissue integration. Biodegradable nanomaterials hold substantial promise for advancing tissue engineering and regenerative medicine, offering effective and sustainable solutions for tissue repair and regeneration.

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