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Contact Name
Adam Mudinillah
Contact Email
adammudinillah@staialhikmahpariangan.ac.id
Phone
+6285379388533
Journal Mail Official
adammudinillah@staialhikmahpariangan.ac.id
Editorial Address
Jorong Padang Panjang Pariangan No. 17 Kec. Pariangan
Location
Kab. tanah datar,
Sumatera barat
INDONESIA
Journal of Advanced Pharmaceutical Research Sciences and Sustainability
ISSN : -     EISSN : 31107117     DOI : 10.70177/japrss
Core Subject : Health,
Journal of Advanced Pharmaceutical Research Sciences and Sustainability is an international peer-reviewed journal dedicated to interchange for the results of high-quality research in all aspect of Pharmacy, Medicinal Chemistry, Social Behavior, and Administrative Pharmacy. The journal publishes state-of-art papers in fundamental theory, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the Journal of Advanced Pharmaceutical Research Sciences and Sustainability follows the open access policy that allows the published articles freely available online without any subscription.
Articles 12 Documents
Life Cycle Assessment of Pharmaceutical Packaging: Strategies for Transitioning to Algae-Based Biopolymers Giorgos Papadopoulos; Eleni Dimitriou; Nikos Konstantinou
Journal of Advanced Pharmaceutical Research Sciences and Sustainability (JAPRSS) Vol. 1 No. 2 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/japrss.v1i2.3634

Abstract

Background. Pharmaceutical packaging plays a crucial role in ensuring drug safety and stability, yet it significantly contributes to environmental degradation due to the extensive use of petroleum-based plastics. Increasing regulatory pressure and global sustainability commitments have intensified the need for environmentally responsible alternatives. Life Cycle Assessment (LCA) offers a comprehensive framework for evaluating the environmental impacts of packaging materials across their entire life cycle. Algae-based biopolymers have emerged as a promising solution due to their renewable origin and biodegradability. This study aims to assess the environmental and functional feasibility of transitioning from conventional polymers to algae-based biopolymers in pharmaceutical packaging. Purpose. A mixed-methods approach was employed, integrating LCA modeling with experimental evaluation of material performance. Representative packaging systems were analyzed using standardized LCA tools to measure global warming potential, energy consumption, water use, and waste generation. Mechanical and barrier properties were tested under controlled laboratory conditions, and comparative analysis was conducted using inferential statistical techniques. Method. Results indicate that algae-based biopolymers significantly reduce carbon emissions, energy use, and waste generation, although they require higher water inputs and exhibit slightly lower mechanical strength. Functional performance remains within acceptable pharmaceutical standards, and environmental improvements are statistically significant. Results. Findings suggest that algae-based biopolymers offer a viable pathway toward sustainable pharmaceutical packaging, balancing environmental benefits with functional requirements.. Conclusion. Representative packaging systems were analyzed using standardized LCA tools to measure global warming potential, energy consumption, water use, and waste generation. Mechanical and barrier properties were tested under controlled laboratory conditions, and comparative analysis was conducted using inferential statistical techniques.
The Climate-Resilient Pharmacy: Evaluating the Stability of Essential Medicines Under Extreme Heat Conditions Jón Jónsson; Guðbjörg Ásgeirsdóttir Ólafur Sigurðsson; Ólafur Sigurðsson
Journal of Advanced Pharmaceutical Research Sciences and Sustainability (JAPRSS) Vol. 1 No. 2 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/japrss.v1i2.3635

Abstract

Background. Climate change is intensifying temperature variability and increasing the frequency of extreme heat events, posing significant risks to the stability of essential medicines. Pharmaceutical storage systems are traditionally designed based on controlled temperature assumptions that may no longer reflect real-world conditions, particularly in climate-vulnerable regions. Purpose. Degradation of medicines under excessive heat can reduce therapeutic efficacy and compromise patient safety. This study aims to evaluate the stability of essential medicines under extreme heat conditions and to assess the resilience of current storage practices. Method. An experimental mixed-methods design was employed, combining climate-simulated heat exposure with laboratory-based stability testing. Selected medicines representing tablets, liquid formulations, and biologics were exposed to sustained and fluctuating temperatures between 40°C and 45°C. Chemical stability, potency retention, and physical changes were measured using validated analytical instruments. Statistical analysis was conducted to identify significant differences across formulations and exposure conditions. Results. Results indicate that biologics are highly susceptible to rapid degradation, while liquid formulations show moderate instability and tablets maintain relatively higher resilience. Temperature fluctuation significantly accelerates degradation compared to constant exposure. Packaging interventions provide partial mitigation but do not fully prevent potency loss. Conclusion. Findings suggest that existing pharmaceutical storage standards are insufficient under extreme heat conditions. Development of climate-resilient storage strategies is essential to ensure drug quality and patient safety.

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