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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 15 Documents
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Search results for , issue "Vol. 59, No. 4" : 15 Documents clear
Front Matter Vol.59 No.4 [12/2023] Indonesiana, Folia Medica
Folia Medica Indonesiana Vol. 59, No. 4
Publisher : Folia Medica Indonesiana

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Back Matter Vol.59 No.4 [12/2023] Indonesiana, Folia Medica
Folia Medica Indonesiana Vol. 59, No. 4
Publisher : Folia Medica Indonesiana

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Hypertension and Lipid Profiles in Middle-Aged Male Patients: A Study at a Tertiary Hospital in Surabaya, Indonesia Nurtya, Arin; Tjempakasari, Artaria; Maimunah, Ummi; , Sulistiawati; Harsa, I Made Subhawa
Folia Medica Indonesiana Vol. 59, No. 4
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Highlights: 1. Uncertainty regarding the association between hypertension and the levels of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) signifies the need for more research, particularly in the realm of sex-specific analysis. 2. Our study uncovered significant associations between hypertension and the levels of total cholesterol and triglycerides, expanding our understanding of the impact of lipid profiles on hypertension. 3. This research may potentially pave the way for personalized diagnostic and therapeutic strategies, ultimately enhancing hypertension management and patient outcomes. Abstract Hypertension is one of the most frequent non-communicable diseases and a risk factor for cardiovascular disease, contributing to most deaths globally. The risk of hypertension is higher in those with uncontrolled lipids. In this study, the incidence of hypertension and lipid profiles were examined from March 2020 to March 2022. The aim of this study was to determine the relationship between hypertension in men aged 45–60 years and their lipid profiles, which include total cholesterol, triglycerides, low-density lipoprotein (LDL), and high-density lipoprotein (HDL). This study used an analytical observational design with a cross-sectional approach. Medical records were utilized as secondary data. Statistical analysis was conducted using the Spearman rank correlation test. Statistical significance was determined at p<0.05. This research examined 115 patients with hypertension. The results showed that the stage of hypertension was correlated with total cholesterol (r=0.317; p=0.001) and triglyceride levels (r=0.217; p=0.02). However, the stage of hypertension was not significantly correlated with LDL (r=0.158; p=0.91) and HDL (r=0.75; p=0.423). Hence, this current study underscores the nuanced relationship between lipid profiles and the stage of hypertension in middle-aged male patients. This study highlights the importance of sex-specific analysis in hypertensive research. It also provides promising avenues for further investigation.
Effect of Short-Term Extra Maltodextrin during a Diet Break on the Resistance Training Performance of Rattus norvegicus Indiarto, Muhammad Irfan; Irwadi, Irfiansyah; Lukitasari, Lina; , Atika
Folia Medica Indonesiana Vol. 59, No. 4
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Highlights: 1. The ongoing advancement of dietary research has significant importance in the exploration of strategies to optimize the impact of nutrition on performance during resistance training. 2. This study provides a prompt for future research to explore the effectiveness of incorporating an additional dietary strategy that may enhance resistance training performance. Abstract: Poor diet with a purpose to lose a certain body weight or body fat can impair muscle protein synthesis. This results in muscle loss and poor performance in physical training, particularly resistance training. This study aimed to determine the short-term effect of extra carbohydrates, specifically in the form of maltodextrin, during a diet break on the resistance training performanced by rats. This study was an experimental laboratory study with a randomized posttest-only control group design. Twenty-seven male rats, aged 3 months with a weight range of 140–165 g, were randomly and equally assigned into three groups: KN (standard diet), KP (75% calorie intake), and K1 (65% calorie intake with a diet break and extra maltodextrin every week). These diets were administered for four weeks, during which the rats had ad libitum feeding. Additionally, the rats underwent ladder-climbing training three times a week. The body weight was measured pre- and post-treatment, while the performance in resistance training was evaluated post-intervention using a ladder climbing platform. There was no significant difference in the weight before and after treatment, with p>0.05 for the increments (∆) among KN (14.00±9.89 g), KP (13±9.5 g), and K1 (20.89±14.77 g). According to the posttest assessment results, only 17 out of 27 rats succeeded in the maximum weightlifting test. This study showed that a short-term high-carbohydrate diet break does not improve the resistance training performance of rats. Further research is necessary to ascertain the outcomes of the treatment implemented over an extended period of time.
An in Vitro Assay Reveals the Anti-Aging Properties of Temulawak Extract (Curcuma xanthorrhiza L.) Wargasetia, Teresa Liliana; Widowati, Wahyu; Muthmainnah, Anis Syabani; , Rizal
Folia Medica Indonesiana Vol. 59, No. 4
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Highlights: 1. This study investigated the potential of temulawak extract as a cost-effective option for cosmeceutical applications in the treatment of aging. 2. Temulawak extract was found to have the ability to inhibit elastase, hyaluronidase, and tyrosinase activities, thus making it a suitable option for cosmeceutical applications. Abstract Aging is the gradual loss of a tissue's capacity to heal and maintain normal or physiological form and function. Elastase, hyaluronidase, and tyrosinase are the enzymes that contribute to the process of skin aging. The anti-aging effect is connected to the inhibition of these enzymes' activities. Numerous medicinal plants with active metabolites have been extensively utilized to treat aging. The active compounds of temulawak (Curcuma xanthorrhiza L.), such as phenolics, curcuminoids, and xanthorrhizol, have promising properties that may be used as anti-aging agents. This study aimed to determine whether temulawak extract, a potential option for cosmeceuticals, has anti-aging properties that can inhibit the enzymes elastase, hyaluronidase, and tyrosinase. A stock solution was made by dissolving 20 mg of temulawak extract in 1 mL of 100% dimethyl sulfoxide (DMSO). The stock solution was then diluted to produce working solutions with concentrations ranging from 31.25 to 1000"‰Î¼g/mL. An in vitro assay was carried out in three replications to examine the anti-aging activity of the temulawak extract. The in vitro assay investigated the inhibition of the enzyme elastase, hyaluronidase, and tyrosinase at seven different concentrations, with the following ranges: 2.08–66.67 μg/mL for the anti-elastase, 5.21–166.67 μg/mL for the anti-hyaluronidase, and 3.125–100 μg/mL for the anti-tyrosinase. IBM SPSS Statistics for Windows, version 20.0 (IBM Corp., Armonk, N.Y., USA) was used to perform the statistical analysis, with a significance level of"¯p<0.05. Temulawak extract exhibited the highest inhibition rates, reaching 82.72%, 89.41%, and 94.17% for the anti-tyrosinase, anti-elastase, and anti-hyaluronidase activities, respectively. The median inhibitory concentrations (IC50) were 10.66, 70.39, and 55.87 μg/mL for the elastase, hyaluronidase, and tyrosinase activities, respectively. This study revealed that temulawak extract has strong anti-aging properties as it effectively inhibits the activities of elastase, tyrosinase, and hyaluronidase. In conclusion, temulawak extract can be considered a promising candidate for cosmeceutical applications.

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