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Yang Yang Endro Arjuna
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Universitas Pelita Harapan, Lippo Karawaci, Tangerang, Indonesia, 15811.
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Lumina: Indonesian Journal of Neurology
Published by Universitas Pelita Harapan
ISSN : 31095658     EISSN : 3109564X     DOI : https://doi.org/10.19166
Core Subject :
Focus and Scope Lumina: Indonesian Journal of Neurology is an open-access, peer-reviewed journal dedicated to advancing the field of neurological sciences, with a focus on both basic neuroscience and clinical neurology. The journal publishes original research, reviews, and intriguing case reports. It also welcomes brief communications that highlight recent advancements in diagnostic techniques, treatments, or other relevant neurological health issues. Additionally, letters and commentaries on previously published articles are encouraged. Topics for publication include, but are not limited to: Neuroepidemiology Neurovascular Neurophysiology Epilepsy Sleep disorders Neurobehavior Neuroimmunology Neurodegenerative diseases Neurootology Neuroophthalmology Neuropediatrics Neurointervention Neuroradiology Neurorestoration Movement disorders Pain management and interventions Neuroendocrinology Neurosurgery Neuropathology Neuroinfection Neuroanesthesiology Neurooncology Neuropharmacology Neuroanatomy
Arjuna Subject : -
Articles 24 Documents
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Impact of Body Mass Index on Pain Severity in Lumbar Facet Arthropathy: An Observational Study Bella Chalista; Yusak Mangara Tua Siahaan; Tasya Pradhana
Lumina : Indonesian Journal of Neurology Vol. 1 No. 1 (2025): April : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i1.9855

Abstract

Background: Lumbar facet arthropathy is a common cause of chronic low back pain (LBP), with increasing evidence suggesting a link between obesity and pain severity. However, the relationship between body mass index (BMI) and pain intensity in facet-mediated LBP remains underexplored. Methods: A cross-sectional study was conducted on 50 patients aged 40–70 with clinically diagnosed lumbar facet arthropathy at Siloam General Hospital Lippo Village between February and June 2022. BMI was calculated and categorised per the WHO Asia-Pacific criteria. Pain severity was measured using the Numerical Rating Scale (NRS). Associations between BMI and pain severity were analysed using Chi-square or Fisher’s exact tests. Results: Most patients were female (52%) and aged 51–60 years (42%). Obesity was prevalent (46%), and 54% of participants experienced severe pain. A significant association was found between higher BMI and pain severity (p = 0.004), with overweight or obese patients having 8.73 times higher odds (95% CI: 2.04–37.30) of reporting severe pain compared to those with normal or underweight BMI. Discussion: These findings suggest a strong relationship between elevated BMI and increased pain severity in lumbar facet arthropathy. Potential mechanisms include increased mechanical loading and systemic inflammation mediated by adipokines. Conclusion: Higher BMI is significantly associated with greater pain severity in patients with lumbar facet arthropathy.
The Relationship Between Stroke Subtypes and Cognitive Function in Ischemic Stroke Patients at Siloam Hospital Lippo Village Maurensia; Vivien Puspitasari
Lumina : Indonesian Journal of Neurology Vol. 1 No. 1 (2025): April : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i1.9856

Abstract

Introduction: Stroke is the second leading cause of death and a major cause of disability worldwide, including in Indonesia, and has an impact on cognitive function. Stroke can be classified based on the Bamford system into: Lacunar Infarct (LACI), Partial Anterior Circulation Infarct (PACI), Posterior Circulation Infarct (POCI), and Total Anterior Circulation Infarct (TACI), each with distinct clinical characteristics and lesion locations. This study aims to analyze the relationship between stroke subtypes and cognitive function in ischemic stroke patients using the MoCA- Ina questionnaire, to understand the clinical symptom differences and predict anatomical lesion sites in ischemic stroke subtypes based on the Bamford classification. Methods: This was a cross-sectional analytical study involving 40 ischemic stroke patients. Data were collected using the MoCA-Ina questionnaire to assess the cognitive function of ischemic stroke patients. Results: There was a significant relationship between stroke subtypes (anterior vs. posterior circulation) and cognitive function in ischemic stroke patients (P-value = 0.000), where patients with anterior circulation involvement showed greater cognitive impairment than those with posterior involvement. Conclusions: There is an association between stroke subtype and cognitive function in ischemic stroke patients at Siloam Hospital Lippo Village, particularly affecting the cognitive domains of language, delayed recall, abstraction, and attention.
Ischemic Stroke Risk Factors in Siloam Lippo Village Teaching Hospital Astra Dea Simanungkalit; Chand Dhiraj Nagpal; Yesenia Tannu Martono; Yusak Mangara Tua Siahaan
Lumina : Indonesian Journal of Neurology Vol. 1 No. 1 (2025): April : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i1.9858

Abstract

Introduction: Acute ischemic stroke is the second leading cause of death worldwide and considered a major health problem leading to significant disability and mortality. Stroke Risk factors epidemiology various among population. This study conducted to identify stroke risk factors in Siloam Lippo Village, a secondary teaching hospital in Banten Province, Indonesia. Methods: This is a cross sectional study of acute ischemic stroke in the Stroke Unit of Siloam Lippo Village Teaching Hospital over a period of 3 months from January 2020 to March 2020. Data regarding the patients’ clinical profile, medical history and diagnostic test results were collected then analyzed using spreadsheet and SPSS version 21.0 software. Results: Forty-eight subjects met inclusion criteria in this study, 25 (52.08%) were male and 23 (47.92%) were female with a mean age of 58.16 ±12.02 years old. The most common risk factor for ischemic stroke in this study is hypertension (83,33%), followed by cigarettes smoking (45,83%), dyslipidemia (51,67%), diabetes mellitus (37,5%), previous stroke (37,5%) and history of heart disease (31,25%). More than 90% of subjects with hypertension and diabetes were uncontrolled. Conclusions: The most common risk factor for ischemic stroke in this study is hypertension and cigarettes smoking, while dyslipidemia, diabetes mellitus, previous stroke and history of heart disease found in more than one-third of the subjects. Uncontrolled status for hypertension and diabetes were more than 90%.
Stress-Induced Belly Dancer’s Dyskinesia in A Young Woman: A Rare Case Report Nadia Gabriella; Rocksy Fransisca V. Situmeang
Lumina : Indonesian Journal of Neurology Vol. 1 No. 1 (2025): April : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i1.9859

Abstract

Background: Belly dancer’s dyskinesia (BDD) is a movement disorder characterized by involuntary and slow writhing, rhythmic contractions of the abdomen. This rarely encountered phenomenon has not been sufficiently explored, with limited evidence regarding its exact pathophysiology, etiology, and treatment. We present a rare case of stress-induced BDD in a 30-year-old female. Case summary: A 30-year-old female presented with a 2-month history of involuntary abdominal movements that were sudden in onset, approximately lasting 5-10 minutes, with preserved consciousness. Her symptoms were initially precipitated by stress. However, they worsened within the past week during her menstrual period. Past medical history was significant for long-standing anxiety disorder and depression, for which she took vortioxetine 10mg/day, clonazepam 0.75mg/day, and lorazepam 0.5mg/day routinely. Upon examination, undulating and continuous movements of the abdominal wall were observed. A diagnosis of BDD was made and the patient was treated with an increased dose of clonazepam 1mg/day. Her symptoms significantly improved within three days. Discussion: Aside from an underlying psychogenic factor, our patient did not have other risk factors for BDD, such as exposure to neuroleptics or history of abdominal trauma. Although certain drugs have been reported to induce BDD, the medications she took have never been reported to cause this condition. Thus, it is most likely that her dyskinesia was stress-induced. Conclusion: Clinicians may not be familiar with BDD due to its infrequency, and the lack of standardized diagnostic and management strategies makes it challenging to diagnose and treat. Therefore, further research and exposure to BDD are imperative.
Postictal Fugue in Temporal Lobe Epilepsy: A Case Report Cindy Prianto; Edeline Samudra; Tiara Julianti; Retno Jayantri Ketaren
Lumina : Indonesian Journal of Neurology Vol. 1 No. 1 (2025): April : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i1.9860

Abstract

Introduction: Temporal lobe epilepsy (TLE) is the most prevalent form of epilepsy. Postictal fugue, a state of altered consciousness and amnesia that can lead to unusual behaviors, is an unusual type of postictal phase in TLE. This case report describes a rare case of postictal fugue in adult-onset TLE. Case Report: A 27-year-old man with complaints of recurrent seizures over the past six years, described as blank staring accompanied by purposeless action with each episode lasting 5-10 minutes on average. During the episodes, he can perform various activities without the ability to recall the events after regaining consciousness. There were neither aura nor specific triggers preceding the episodes. Some long-term memories are impaired. No other cognitive impairment is found. There was a long-standing history of substance use. Electroencephalogram examinations revealed abnormal spikes wave in bilateral temporal region. Discussion: The patient’s symptoms resemble dissociative fugue but is attributed to an organic etiology, which is mesial/limbic TLE. The postictal phase which manifests as postictal fugue is caused by the abnormal electrical activity in the hippocampus leading to disruption in memory formation and spatial navigation. The underlying mechanism causing epilepsy is thought to be related to the prolonged history of substance abuse. Conclusion: The postictal phase in TLE can present in various forms and may be challenging to diagnose. Therefore, it is crucial to thoroughly investigate the causes of organic dissociative disorder, including postictal fugue in TLE.
Lactate Dehydrogenase as A Potential Prognostic Biomarker in Subarachnoid Haemorrhage: A Systematic Review Yang Yang Endro Arjuna; Alexander Erick Purnomo; Jeremiah Hilkiah Wijaya; Mary Christina Elsa; Yusak Mangara Tua Siahaan; Made Agus Mahendra Inggas; Randra Frits Christopher; Michelle Gloria Setiawan; Haddiyya Wardhani Nugroho
Lumina : Indonesian Journal of Neurology Vol. 1 No. 1 (2025): April : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i1.9861

Abstract

Background: Subarachnoid haemorrhage (SAH) lacks specific prognostic blood markers, but lactate dehydrogenase (LDH), linked to cellular damage, shows potential for predicting adverse outcomes in SAH patients. Elevated LDH levels may reflect anaerobic metabolism and tissue injury following SAH, providing insight into disease severity and complications. This review explores the relationship between lactate dehydrogenase levels and outcomes in SAH patients. Method: A systematic review was conducted using PubMed, Europe PMC, ScienceDirect, and Google Scholar, searching for terms like "Lactate Dehydrogenase," "LDH," "Subarachnoid Haemorrhage," and "Outcome" up to March 3, 2025. Studies comparing LDH levels with Modified Rankin Score (mRS) and secondary outcomes such as Hunt-Hess grade, Fisher grade, complications, and mortality were included. Result: Seven studies involving 5,985 participants met inclusion criteria. Higher LDH levels correlated with worse mRS scores, increased delayed cerebral ischemia (DCI), postoperative pneumonia, severe Hunt-Hess and Fisher grades, and higher mortality. Using the ROBINS-I tool, four studies showed low risk of bias, and three had moderate risk. Discussion: Elevated LDH levels predict adverse outcomes in SAH, highlighting its prognostic value. As a marker of cellular damage and anaerobic metabolism, LDH reflects tissue injury and hypoxia post-SAH, explaining its link to complications like delayed cerebral ischemia (DCI) and pneumonia. This physiological basis supports its role in risk stratification, aiding early identification of high-risk patients for targeted interventions and improved outcomes. Conclusion: Early measurement of LDH levels after SAH onset may help predict patient outcomes and complications, aiding clinical decision-making and improving patient management strategies.
Association between Flat Foot Severity and Low Back Pain Recurrence among Pre-Clinical Medical Students: A Cross-Sectional Study Annisa Ummi Hafizhah Arif Fiyanto; Vonny Fibrianty Goenawan
Lumina : Indonesian Journal of Neurology Vol. 1 No. 2 (2025): August : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i2.10280

Abstract

Background: Low back pain (LBP) affects over 619 million people globally and is highly prevalent among medical students. Flat foot (pes planus), a biomechanical alteration involving the collapse of the medial longitudinal arch, may contribute to spinal stress and LBP recurrence, yet remains underexplored in young adult populations. Methods: This cross-sectional study involved 67 pre-clinical medical students aged 19–23 years with a history of recurrent LBP in the past year. LBP frequency was assessed using the Nordic Musculoskeletal Questionnaire and Numeric Rating Scale (NRS). Foot arch structure was evaluated via Clarke’s Angle, classifying flat foot severity into mild (35°–41°), moderate (30°– 34.9°), and severe (<30°). Data were analysed using Chi-square tests, with significance set at p < 0.05. Results: LBP was reported by 80.6% of participants, with flat foot classified as mild in 43.3%, moderate in 37.3%, and severe in 19.4%. A significant association was found between flat foot severity and LBP recurrence (p < 0.001). Students with mild or moderate flat foot had a lower odd of experiencing moderate-frequency LBP compared to those with severe flat foot (OR = 0.152 95% CI: 0.048–0.483). Discussion: These findings support the notion that structural abnormalities of the foot, particularly flat foot, may contribute to the recurrence and persistence of LBP by influencing spinal posture, altering mechanical load distribution, and affecting neuromuscular stability. Conclusion: Flat foot severity is significantly associated with the recurrence of LBP in medical students. Early identification and foot posture assessment may help inform preventive and corrective interventions for recurrent LBP.
Addiction to Online Games Affects The Attention Levels Of Medical Students Of Pelita Harapan University Johanes David Hendrijanto; Claudia Kinsky Irawan1 Irawan; Vivien Puspitasari
Lumina : Indonesian Journal of Neurology Vol. 1 No. 2 (2025): August : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i2.10281

Abstract

Background: Epidemiologically, the incidence of online games addiction in students in Indonesia in 2013 is estimated to be around 10.15%. Addiction to online games is one of the factors that might affect a person’s level of attention. Previous studies had shown that there are positive and negative effects of attention function. There are also several studies that have reviewed the relationship between online games addiction and cognitive function but only a few studies focus on the level of attention. The study was conducted to determine the relationship of online games addiction with the level of attention to students. Methods: This study uses a cross-sectional method. A sample of 158 peoples, who are students of the Faculty of Medicine at the University of Pelita Harapan in 2017 and were selected using a purposive technique. Data was collected from February to March 2020. The results were processed with Chi Square using SPSS version 25.0 software. Results: Of the 158 samples needed, only 97 samples were collected due to COVID-19 and power by 56%. Of the 93 samples that met the inclusion criteria, 22.6% were addicted to games. In the game’s addiction group, it was found that 23.8% experienced a decrease in forward attention and 57.1% experienced a decrease in backward attention. (forward: p value = 0,000, backward: p value = 0,001). Conclusion: In conclusion, a significant relationship was found between online game addiction and decreased attention levels.
Association between Daily Tea Consumption and Sleep Quality: A Cross-sectional Analytical Study Gabriella Beatrice; Tasya Meidy Pradhana; Yusak Mangara Tua Siahaan
Lumina : Indonesian Journal of Neurology Vol. 1 No. 2 (2025): August : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i2.10284

Abstract

Background: Sleep quality is a critical determinant of physical and mental health, and dietary factors such as caffeine intake from tea may influence sleep patterns. Evidence on this association in the Indonesian population remains limited despite the high prevalence of both tea consumption and poor sleep quality. This study aimed to investigate the relationship between daily tea consumption and sleep quality among Indonesian adults. Methods: A cross-sectional correlational study was conducted from January to March 2022 using an online survey. A total of 104 adults aged 18–64 years with low stress levels (Perceived Stress Scale score ≤13) were included. Tea consumption was assessed by frequency and quantity (cups/day), while sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI). A global PSQI score >5 indicated poor sleep quality. Data were analyzed using Spearman’s rank correlation, with significance set at p < 0.05. Results: Most participants were female (61.5%), aged 20–49 years, with 40.4% consuming ≥3 cups of tea daily. Poor sleep quality was reported by 72.1% of respondents. A significant positive correlation was found between daily tea consumption and PSQI score (rₛ= 0.528, p < 0.001), indicating that higher tea intake was moderately associated with poorer sleep quality. Conclusions: Higher daily tea consumption is significantly associated with poorer sleep quality among Indonesian adults. These findings underscore the need for public health initiatives to raise awareness about caffeine-containing beverages and their potential effects on sleep.
The Relationship Between Body Mass Index and The Degree of Dementia in Elderly Patients with Memory Impairment at Memory Clinic Siloam Hospitals Lippo Village Nathan Muliawan; Maurensia; Rocksy Fransisca Situmeang
Lumina : Indonesian Journal of Neurology Vol. 1 No. 2 (2025): August : Lumina : Indonesian Journal of Neurology
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/lijn.v1i2.10285

Abstract

Introduction: Body mass index (BMI) can describe the level of nutrition and vitality of a person. Monitoring BMI values prevents elderlies from various risks of disease, one of which is dementia. The development of neuropathological lesions in the olfactory bulb has been proposed to cause symptoms which affect dementia patients’ appetite and thus resulting in weight loss. Methods: A cross-sectional study was conducted among 55 memory impairment patients from ages ≥65 years at Siloam Hospitals Lippo Village Memory Clinic. Data was obtained using Montreal Cognitive Assessment – Indonesian Version (MoCA-INA) and Clinical Dementia Rating Scale (CDRS) and BMI was measured using Seca 703 instrument. Results: A significant relationship was found between body mass index and the degree of dementia with a value of p = 0.046 for MoCA examination and p = 0.039 for CDRS examination. The results of the analysis shows that underweight-normal (BMI <23kg/m2) patients have 3.8 times (95% CI 1.2-12.5) and 4.6 times (95% CI 1.2-17.0) the risk of having a moderate-severe degree respectively compared to overweight-obese (BMI ≥23kg/m2) patients. Conclusions: Lower late life BMI is related to higher degree of dementia

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