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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 34 Documents
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Search results for , issue "Vol 50, No 1 (2018)" : 34 Documents clear
Risk Factors for Acute Otitis Media in Children at Dr.Soedono Hospital Jeem Yaltafit Abror; Andriani Russy Novita; Suwondo Slamet
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018): SUPPLEMENT
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.893 KB) | DOI: 10.19106/JMedScieSup0050012018013

Abstract

Acute otitis media (OMA) was the most common ear infection in children. Because of  Tuba Eustachius was  not developed  yet, shorter and flatter / horizontal   in children so the secretions of   nasopharynx were easier to enter the middle ear. OMA can cause many complications such as subperiosteal abscess to severe complications like meningitis and brain abscess. Epidemiological studies of OMA in developing countries were still rare. The prevalence of OMA was different in many country, ranging from 2.3 - 20%. The result of   study showed that the prevalence of OMA in children in East Jakarta was 5.38%, and the highest prevalence was on group among 2-5 years old. 179 patients analyzed  were 50.8% male and 49.2% female. The mean age of this study subjects was 4.75 years (SD 4.54). 31.3% were diagnosed with OMA. There was no difference in the location of the OMA occurrence between the right and left ear. There was a significant correlation between age factor and the incidence of OMA (p = 0.014) and subjects which under 5 years of old became a risk factor for OMA. The results also showed that there was a correlation between treatment and the incidence of OMA (p = 0.000), ARI patients without treatment was being a risk factor for the incidence of OMA in children. There was no correlation between sex, type factor and health insurance against the occurrence of OMA.
Child tuberculosis in Respira Lung Hospital, Yogyakarta: demographic and clinical profiles Stefani Candra Firmanti; Rina Triasih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018): SUPPLEMENT
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.838 KB) | DOI: 10.19106/JMedScieSup0050012018010

Abstract

Tuberculosis (TB) remains a significant source of morbidity and mortality among children in endemic settings. Demografic and clinical profiles of children with TB in Yogyakarta have not been well documented. A total of 80 children with TB were diagnosed with TB during the study period. There were 41 (51.2%) females and 39 (48.8%) males. The case findings of child TB cases has been increasing from 20 cases in 2014, 28 cases in 2015, and 32 cases in 2016. The majority of the children (89.3%) aged less than 5 years. The most common symptoms were cough 50 (62.5%), followed by weight loss 45 (56.3%), and fever 28 (35%). Contact with a TB case was identified in 46 (57.5%) children. Mantoux test was  done  in  76  (95%)  children  with  positive  result  documented  in  61(76.3%) children. Chest X-ray was done in 54 (67.5%) children, of which 52 (65%) chest X- rays showed suggestive of TB. Confirmed diagnosis (bacteriology) was only documented in one child (1.25%).
The SLCO1B1*15 haplotype associated with lower clinical outcome in Indonesian tuberculosis patients Sunarto Ang; Akhmad Kharis Nugroho; Ahmad Hamim Sadewa; Lukman Hakim; . Mustofa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.494 KB) | DOI: 10.19106/JMedSci005001201806

Abstract

Rifampin is one of first-line drugs for the treatment of tuberculosis. In Indonesia nearly alltuberculosis patients show lower rifampin plasma concentrations possibly due to genetics.Rifampin is a substrate of the organic anion-transporting polypeptide 1B1 (OATP 1B1)encoded by the solute carrier organic anion transporter family member 1B1 (SLCO1B1).This study aimed to identify haplotype polymorphisms of tuberculosis drug transporterswith an impact on clinical outcome in tuberculosis patients. Thirty-six patients from AbdulWahab Sjahranie General Hospital, Samarinda, East Kalimantan were involved in thestudy. Buffy coat from patient blood samples were tested for SLCO1B1 and SLCO1B3polymorphisms by RFLP and ARMS PCR, whereas the clinical outcome was examinedbased on the sputum conversion. The frequency of patients with SLCO1B1*15 haplotypewas 63.9%. The SLCO1B1*15 haplotype was associated with susceptibility to failureof clinical outcome (p=0.005; RR=4.52; 95% CI: 1.22-16.64). The OATP1B1*15haplotype revealed that the failure of clinical outcome was markedly increased comparedto the three other haplotypes. These results suggest that the SLCO1B1*15 haplotypeis an important predisposing factor for lower clinical outcome. Our data indicate thatindividualized treatment should be considered for Indonesian tuberculosis patients basedon genetics characteristics of patients.
Healthcare-associated infections (HAI) research in Asian countries: a bibliometric analysis . cahyadin; Ahmad Watsiq Maula; Anis Fuad
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018): SUPPLEMENT
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.188 KB) | DOI: 10.19106/JMedScieSup005001201801

Abstract

Health care-associated infections (HAI) are the most frequent adverse event in health-care delivery worldwide, including in Asian countries. Asian countries produced 4,819 HAI publications. Majority of the publications (68%) appeared in the last decade. The average annual growth rate was 14.8%. Japan was the most productive country that contributes about 13.5% of total publications, followed by China (11.7%), and Taiwan (11.6%). Asian HAI research were cited in 76,737 articles with an average of 15.9 citations per publication. The top two most highly cited articles were published in the New England Journal of Medicine followed by the Journal of Clinical Microbiology. The top three productive journals were Journal of Hospital Infection (309 papers; 6.4%), American Journal of Infection Control (198 papers; 4.1%) and Infection Control and Hospital Epidemiology (170 papers; 3.5%). The ten top journals contained 25% of the HAI literatures. Emerging research topics in the last years include ventilator-associated pneumonia, MRSA (methicillin-resistant staphylococcus aureus), acinetobacter baumannii, carbapenems, Republic Korea and tertiary care center.

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