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INDONESIA
EKSAKTA: Journal of Sciences and Data Analysis
Published by Universitas Islam Indonesia
ISSN : 27160459     EISSN : 27209326     DOI : 10.20885
Core Subject : Science, Engineering,
Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Materials Science & Nanotechnology
Ekstakta is an interdisciplinary journal with the scope of mathematics and natural sciences that is published by Fakultas MIPA Universitas Islam Indonesia. All submitted papers should describe original, innovatory research, and modelling research indicating their basic idea for potential applications. The Journal particularly welcomes submissions that focus on the progress in the field of mathematics, statistics, chemistry, physics, biology and pharmaceutical sciences.
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 8 Documents
 1 
Search results for , issue "VOLUME 18, ISSUE 1, February 2018" : 8 Documents clear
The Effect of CaO Weight from Snail Shell (Pilla Ampullacea) On Its Activity As Heterogeneous Catalyst on Biodiesel Conversion Of Bran Oil Hikmah Fatmawati; Wellyana Puspitasari; Rohini Pujiarti; Sesy Ardyanti; Is Fatimah
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art7

Abstract

Research on utilization of snail (Pilla ampullacea) shell as CaO source for biodiesel conversion from rice bran oil has been investigated. CaO was derived by calcining the shell at pada 900oC for 2 h. The powder obtained from the process was characterized using x-ray diffraction (XRD),  energy dispersive x-ray (EDX), Fourier-Transform Infra-red (FTIR) and surface basicity test. In order to test the activity of catalyst, effect of catalyst weight on the yield of conversion as studied. Results show that the derived material is composed from dominantly CaO and the material demonstrates activity in rice bran conversion into biodiesel. Compared to  NaOH, the CaO catalyst exhibits more effectively active as shown by the higher yield. From varied catalyst weight, it is obtained that at the range of 2.5-10% catalyst weight does not affect significantly to the increasing yield. 
An Investigation of Insect Ovipositing Repellent Activity of Andrographis paniculata Ness, Acacia auriculiformis and Piper betle Linn Leaves Extracts to Batrocera carambolae Nurcahyo Iman Prakoso; Umul Azizah; Zahrah Nur Zakiyah; Mila Tria Nita; Arida Liyanita; Suputa Suputa
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art1

Abstract

Batrocera carambolae was one of the main pests in some types of fruits. This pest attack resulted in quantitative damage in the form of fall of young fruit and qualitatively in the form of fruit to rot and contains maggots. This research was conducted to determine selected extract from Andrographis Paniculata Ness, Piper betle Linn and Acacia auriculiformis leaves which have repellent activity for Batrocera carambolae. Nine extracts from the maceration process of the three leaves were evaluated by placing the extracts and flies together in the cage. The ethanol, ethyl acetate, and n-hexane extracts from Andrographis Paniculata Ness, Piper betle Linn and Acacia auriculiformis leaves were applied to the test pieces and fed into a cage containing 10 male and female flies. From observation, N-hexane extracts from Andrographis Paniculata Ness and Piper betle Linn leaves and ethyl acetate extracts from Acacia auriculiformis leaf  having good activity as repellent and potentially to be used as a insect ovipositing repellent of Batrocera carambolae.
Survival Analysis of Child Patient Diarrhea Using Kaplan Meier Method and Rank Log Test Muhammad Muhajir; Yayi Diyah Palupi
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art8

Abstract

Diarrhea being one of public health problems that important because it is third major contributor the pain children in various countries including indonesia. This research using data from islam hospital medical record jakarta in january 2017 shows that diarrhea cases were occupying the highest rank of various types of disease in patients children, using indicators long healed patients , the age of , andsex. Methods used to determine function survival who dominated in patients children are Kaplan Meier and Log Rank. The results of the analysis method kaplan meier got that patients male had the probability of healed longer than for patients female as well as patients age of 6- 11 years had the probability healed longer than the age of ≤ 5 years. To Log Rank test got that there is no significant difference between the survival function based on sex and age patients.
Formulation and Evaluation of Kaptopril Tablets Using Threaded Amylum Tubes and HPMC as Fillers and Binders of the Direct Method Ahmad Sastra Kelana; Aris Perdana Kusuma; Oktavia Indrati
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art2

Abstract

Indonesia is a tropical country which has many potential plants as excipients, likestarches and tubers. Amylum of taro tuber (Colocasia esculenta) has the potential to be developed into excipient but its use is limited. The purpose of this study was to optimize the formulation and to evaluate the characteristics of captopril tablets by using amylum of taro tuber and HPMC modified as filler and binder on direct compression method. Amylum of taro tuber was obtained by extraction process, then combined with HPMC by partial pregelatination and co-process method. Variation of the starch was divided into five formulation. The main test included friability test, hardness test, dissolution test, and assay. The data analysis was done by theoretical approach between the evaluation result and the literature to observe the result of the modification formulation. It indicated that the combination of equal amount of taro amylum and microcrystalline cellulose (MCC) pH 102 (50% : 50%) has the best result among others. Friability percentage was 0.17 ± 0.07%, disintegration time was 12.09 ± 0.52 minutes, assay was 97.88 ± 1.71% and dissolution test results was 90.65 ± 4.81%.
Effervescent Tablet Formulation Melinjo Seed Extract (Gnetum gnemon L.) Using PEG 6000 As Lubricant and Citric Acid - Tartaric Acids As Acid Sources Puput Andi Apsari; Dewi Nur Eka Sari; Aris Perdana Kusuma; Oktavia Indrati
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/Eksakta.vol18.iss1.art4

Abstract

Melinjo seeds (Gnetum gnemon L.) have antioxidant properties one of which is from phenol compounds. However, there is no pharmaceutical dosage form of melinjo seeds especially effervescent tablet. The purpose of this research was to determine the best variation of citric-tartaric acid and PEG 6000 from effervescent tablet of melinjo seed extract. The effervescent tablet of melinjo seed extract were formulated with variation of citric-tartaric acid 25%:75%, 65%:35%, 50%:50%, 20%:80% and PEG 6000 0%, 2%, 3%, up to 5%. The effervescent tablet were made by melting parts of acids and bases, added with extract and other ingredients. The evaluation included flow and powder tapping, tablet hardness, weight variation, friability, and tablet solubility test. The data were analyzed by comparing approaches based on the requirements of Pharmacopeia Indonesia V andUnited States of Pharmacopeia 36.Variations of equal amount of citric-tartaric acid produced hard effervescent tablets with small friability. The unbalanced acid concentration resulted in higher friability. The greater the concentration of citric acid resulted in the longer solubility of the tablet. The addition of PEG 6000 made the flow time of granules quicker, while higher concentrations would increase the hardness of tablets and accelerate the soluble time. Excessively high concentrations resulted in a high degree of friability. Variation of citric-tartaric acid and PEG 6000 influenced physical properties of granule and effervescent tablet extract of melinjo seeds, such as flowability, hardness, friability, and solubility of the tablet.
Determination of Phytochemical Compounds (Tannins, Saponins and Flavonoids) as Quercetin In Inggu Leaf Extract (Ruta angustifolia L.) Shafa Noer; Rosa Dewi Pratiwi; Efri Gresinta
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art3

Abstract

Empirically, Inggu leaves (Ruta angustifolia L.) has potential to be used as raw material of traditional medicine because it contains phytochemical substances. The main organ most widely used as a traditional medicine is its leaves. Phytochemical compounds contained in the leaves of inggu include quercetin, tannin and saponins. Quercetin is a class of flavonol compounds (part of flavonoids). Quercetin has the ability to prevent the oxidation process from low density lipoprotein (LDL) by capturing free radicals and inhibiting transition metals, so that quercetin is believed to protect the body from various degerative diseases. While flavonoids are compounds consisting of 15 carbon atoms thatact as plant pigments. The function of flavonoids is to protect the cell structure, increase the effectiveness of vitamin C, antiinflammatory and as an antibiotic. While saponin and tannin are a group of active compounds of plants that have a sense of bitter and have antibacterial activity. This study was aim to determine the number of quercetin, tannins and saponins contained in the inggu’s leaves. Preparation of inggu leaf sample was done by maceration extraction technique used 96% ethanol solvent. Analysis of tannin and quercetin levels was determined by UV-Visible Spectrophotometry at 725 nm wavelength (λ).While the analysis of saponin content using TLC Scanner at 301 nm wavelength (λ). The results showed that content of quercetin was 1.67%; saponins 2.13% and tannins 7.04%.
The Bactericidal and Antibiofilm Activity of Stem Bark of Jatropha multifida L. Against Staphylococcus aureus and MRSA Annisa Fitria
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art5

Abstract

Chronical wound often caused by bacteria which has antibiotic resistance characteristic and presence of biofilm formation. This study aims to evaluate the bactericidal and antibiofilm activity of stem bark of Jatropha multifida L. against Staphylococcus aureus and MRSA (Methicillin-Resistant Staphylococcus aureus), as alternative antimicrobial agents. Examination of bactericidal activity of the extract was performed by time-kill assay to determine the speed of the extract to eradicate bacteria. The inhibitory activity of extract toward biofilm production was quantified using spectrophotometric method. The extract showed bactericidal activity which can be achieved at 8 hours and 12 hours against Staphylococcus aureus and MRSA in MBC value of 0.5 mg/mL and 1 mg/mL. The extract exhibited antibiofilm activity which indicates by its IC50 value of 0.3 mg/mL and 0.76 mg/mL against Staphylococcus aureus and MRSA. These experiments have shown the potential of the extract of  Jatropha multifida L. stem bark as a bioactive substance in a topical agent for chronical skin infection.  
Estimation of Exponential Smoothing Parameter on Pesticide Characteristic Forecast using Ant Colony Optimization (ACO) Dinita Rahmalia
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 18, ISSUE 1, February 2018
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol18.iss1.art6

Abstract

Pest in agriculture can raise plant disease and fail to harvest. The pest problem in agriculture can be solved by using pesticide. Pesticide usage must be done proportionally. So, the manufacturer should fix standard pesticide active ingredient in pesticide production. Forecast is a prediction of some future evens. In forecast problem, there are any parameters which should be determined. Parameters can be estimated by exact method or heuristic method. Ant Colony Optimization (ACO) is inspired from the cooperative behavior of ant colonies, which can find the shortest path from their nest to a food source. In this research, we use heuristic method like ACO to estimate exponential smoothing parameter on pesticide active ingredient forecast and pesticide sample weight forecast. From the simulation, on the first iteration, all ants choose parameter randomly. At the optimization process, we update pheromone until all ants choose the similar parameter so that process converges and variance approaches to zero. The optimal exponential smoothing parameter can be applied in forecasting with minimum sum of squared error (SSE).

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