Althea Medical Journal
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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<![CDATA[Effect of Carica Papaya L Leaf Infusion on Transporting Glucose across Small Intestine Cell Membrane of Wistar Rats Model ]]>
<![CDATA[Srisathis Renganathan]]>;
<![CDATA[Vycke Yunivita]]>;
<![CDATA[Anna Martiana S]]>;
<![CDATA[Nida Suraya]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.512
<![CDATA[Background: Carica papaya L leaf is one of the common types of plant that has been used as treatment for diabetes mellitus (DM). The leaf possibly contain quercetin, which may inhibit glucose transport through cell membrane of small intestine. This study was conducted to determine the effect of Carica papaya L leaf infusion on glucose transport in Wistar rat model.Methods: A one-group pretest-posttest explorative study was designed using perfusion method. Nine male rats were fasted for 18-24 hours before dissected. A 25 mL glucose solution was given as early control, before Carica papaya L leaf infusion treatment A 25 mL glucose solution was later given again after Carica papaya L leaf infusion as late control. Artificial perfusion equipment had been used to maintain the back and forth flow of glucose in the small intestine. Sample was taken every 15 minutes for one hour for each treatment.Results: Carica papaya L leaf infusion did not decrease the concentration of glucose absorption significantly compared to early control. The mean absorption of glucose in early control was 85.39+4.42 mg/dl and during treatment was 84.51+4.20 mg/dL.Conclusions: Carica papaya L leaf infusion does not have significant inhibiting effect on glucose transport across small intestine cell membrane. Further explorative study is required.]]>
<![CDATA[Identification of Enteric Bacterial Pathogens in Beverages Sold By Hawkers around Jatinangor, Bandung ]]>
<![CDATA[Teow Sheng Hao]]>;
<![CDATA[Yanti Mulyana]]>;
<![CDATA[Bachti Alisjahbana]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1536
<![CDATA[Background: Water is essential for life and is considered as a medium for the propagation and dissemination of bacteria. Water-borne disease is one of the problems in Indonesia, therefore, this study was conducted to explore the presence of enteric bacterial pathogens in the beverages sold by hawkers.Methods: A descriptive laboratory method was conducted in September 2015 Beverages were collected from hawkers that were randomly chosen around Jatinangor using sterile containers, and brought to the laboratory within 1 hour. The beverages were incubated on Mueller Hinton Broth, followed by culturing on MacConkey Agar. The organisms were identified using Gram Staining, Kliger Test, Motility-Indole-Urease test and Citrate test.Results: Out of 30 samples collected, 2 of the samples were tested positive for enteric bacterial pathogen Salmonella paratyphi. Furthermore, Klebsiella pneumoniae (n=12), Enterobacterspp (n=10) Alcaligenes faecalis (n=3) and Pseudomonas spp. (n=3) were detected in the samples.Conclusions: The Salmonella paratyphi as enteric bacterial pathogen found in the beverages sold by hawkers has potential to cause water-borne disease. Education to hawkers need to be enhanced.]]>
<![CDATA[Exclusive and Non-Exclusive Breastfeeding among Stunted and Normal 6–9 Month-Old-Children in Jatinangor Subdistrict, Indonesia ]]>
<![CDATA[Viramitha Kusnandi Rusmil]]>;
<![CDATA[Tri Oktaviani Prahastuti]]>;
<![CDATA[Dimas Erlangga Luftimas]]>;
<![CDATA[Tisnasari Hafsah]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1598
<![CDATA[Background: Stunting has become a public health problem in Indonesia, with the prevalence of stunting is 37.2% nationally and 25.6% in West Java. One of the causes of stunting is malnutrition that may occur because of not giving exclusive breastfeeding on the first 1000 days of life (FDL). The purpose of this study was to determine whether there was difference between exclusive and non-exclusive breastfeeding among stunted and normal 6–9 month-old-children. Methods: This study was conducted using a cross-sectional analytic study during August-October 2018 with consecutive sampling method. This study involved 110 pairs of mothers and children aged 6-9 months who resided in villages which were within the work area of Jatinangor Public Health Center. Nutritional status was determined based on length-for-age z score according to WHO. The type of breastfeeding was known based on the questionnaire. Data was analyzed by chi square test. Result: There were 60 of 110 children (54.5%) who did not receive exclusive breastfeeding. The incidence of stunting in children was 12.7% (14 of 110), of whom 10 children had no exclusive breastfeeding (p>0.05).Conclusions: Although the incidence of stunting is higher in non-exclusive breastfeeding group, there is no difference in the proportion of stunting in children aged 6–9 months between those who are exclusively breastfed and those who are not, however, exclusive breastfeeding is encouraged.]]>
<![CDATA[Alcohol Addiction and Cognitive Function among Café Visitors at South Jakarta ]]>
<![CDATA[Andrew Suwadi]]>;
<![CDATA[Dharmady Agus]]>;
<![CDATA[Stefanus Lembar]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1604
<![CDATA[Background: Alcohol addiction has an acute and chronic impact, and may cause cognitive function impairment, in the form of interference in decision making and impulse control, as well as impaired motor function. Furthermore, research on alcohol addiction and cognitive function has not been widely studied in Indonesia. The purpose of this study was to explore the association between alcohol addiction and cognitive function among café visitors at South Jakarta. Methods: This was a cross sectional study, conducted among cafévisitors at South Jakarta in 2018. The respondents of this study were individuals who have consumed alcohol in the last 12 months and not consumed narcotics, psychotropic, and other addictive substances except nicotine and caffeine. Alcohol addiction among respondent was assessed by the CAGE questionnaire and cognitive function was assessed by the MoCA-Ina questionnaire. Statistical analysis was determined by Chi Square test.Results: In total, 80 respondents consisting of 57 men and 23 women met the study criteria, 67.5% of respondents have experienced alcohol addiction and 85.2% have experienced poor cognitive function. There was a strong association between alcohol addiction and cognitive function among café visitors (p=0.000; OR=44.083).Conclusions: Individual with alcohol addiction has a poor cognitive function compared with people without alcohol addiction. Therefore, awareness of the adverse effects of alcohol addiction on cognitive function among community is needed and thus, people are expected to distance from alcohol addiction.]]>
<![CDATA[Etiology of Symptomatic Focal Epilepsy based on Neuroimaging Result in Neurology Outpatient Clinic of Dr. Hasan Sadikin General Hospital ]]>
<![CDATA[Agastya Prabhaswara]]>;
<![CDATA[Suryani Gunadharma]]>;
<![CDATA[Uni Gamayani]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1556
<![CDATA[Background: Focal epilepsy is the most common type of epilepsy that can be caused by structural lesions. Images from neuroimaging can show those structural lesions that may point to the etiology of epilepsy and would affect the management of epilepsy. The aim of the study was to explore the possible etiology of symptomatic focal epilepsy from neuroimaging result at the Neurology Outpatient Clinic in Dr. Hasan Sadikin General Hospital.Methods: This study was a cross-sectional descriptive study. The medical records that fulfilled the inclusion criteria were collected at the Neurology Outpatient Clinic of Dr. Hasan Sadikin General Hospital from the year 2017. The inclusion criteria were symptomatic focal epilepsy patients that had abnormal neuroimaging result.Results: In total, there were 71 medical records collected of which eight etiologies of symptomatic focal epilepsy were found, that were vascular disorder caused by strokes (33%), tumors (21%), hippocampal sclerosis (20%), infections (11%), head trauma (6%), malformations of cortical development (4%), vascular malformations (3%), and phakomatosis (1%). Vascular disorder was the most abundant etiology found in all brain lobes, except in temporal and frontal lobes, which also most often caused by hippocampal sclerosis and tumors, respectively.Conclusions: Vascular disorders due to stroke, is the most abundant etiology found in symptomatic focal epilepsy, therefore, stroke patients need to be informed about the possibility of having epilepsy later on.]]>
<![CDATA[Cardiorespiratory Endurance among End Year Student of Faculty of Pharmacy in Jatinangor, Bandung ]]>
<![CDATA[Hemavahthy Mani]]>;
<![CDATA[Tri Damiati Pandji]]>;
<![CDATA[Putri Teesa]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.511
<![CDATA[Background: Physical fitness indicates the ability of an individual to perform daily physical activities with ease. The major component of physical fitness is the cardiorespiratory endurance, which is assessed through maximal oxygen consumption (VO2 max). A decrease in cardiorespiratory endurance can be associated with a sedentary lifestyle. This study was conducted to determine the cardiorespiratory endurance among young adults in Jatinangor, Bandung.Methods: This cross-sectional study had used total sampling method, conducted among end year student of Faculty of Pharmacy, Universitas Padjadjaran from October–November 2013. The inclusion criteria wasall end year students who had no health-related problems and the students had to agree to participate in the study. After obtaining written informed consent from the participants, Astrand-Rhyming Step Test was performed to measure the level of VO2max.Results: In total, 32 students were included of whom 14 students (43.7%) had an average level of VO2 max and 9 (28.2%) had just below average level. Chi-square test results showed that there was no significant relationship (p>0.05) between VO2 max level and gender, BMI level, and smoking habit, but showed a significant relationship (p< 0.05) with exercising habit.Conclusions: The majority of the participants had an average level of VO2 max. A significant relationship between the level of VO2 max and exercising habit, suggesting a regular exercise for a better lifestyle.]]>
<![CDATA[Generalized Seizure Due To Acute Hyperosmolar Hyponatremıa Followıng Coronary Angıography: A Lesson Learned From A Case Report ]]>
<![CDATA[Mehmet Coᶊgun]]>;
<![CDATA[Yilmaz Gunes]]>;
<![CDATA[Isa Sincer]]>;
<![CDATA[Aslı Mansiroglu]]>;
<![CDATA[Oğuz Kayabaᶊi]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1356
<![CDATA[Hyponatremia is a common electrolyte disorder, but symptomatic hyponatremia following coronary angiography is rare. Although patients with hyponatremia are generally asymptomatic, neurological manifestations may result in lethal complications.Here we presented a 69-year-old female, admitted for elective coronary angiography due to exertional chest pain. Seven hours later after coronary angiography, however, the patient had a headache, temporary mental confusion and her speech was slurring. A brain magnetic resonance imaging (MRI) test, arterial blood gas analysis, and the neurological examination were carried out. The neurological examination showed no focality and brain diffusion MRI was normal. Arterial blood gas analysis revealed sodium of 110 mmol/L and potassium of2.8 mmol/L. The patient was treated with hypertonic saline (3% NaCl) and vasopressin antagonist tolvaptan 15 mg at first and isotonic saline (0,09 NaCl) with a gradual normalization of electrolytes. Diagnosis of acute hyperosmolar hyponatremia should be considered in patients with developing mental or behavioral abnormalities following coronary angiography.]]>
<![CDATA[Serum Trace Elements and Antioxidant Vitamins among Male Patients with Prostate Disorders in the Delta Region of Nigeria ]]>
<![CDATA[Bhaguetai Joseph Aghawegbehe]]>;
<![CDATA[Adedeji David Atere]]>;
<![CDATA[David Bolaji Akinbo]]>;
<![CDATA[Olumide Faith Ajani]]>;
<![CDATA[Raphael Usiosefe Erhunmwunse]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1597
<![CDATA[Background: Prostate cancer remains the commonest form of cancer among Nigerian males, constituting 13.3% of all male cancers encountered in this region. Trace elements and antioxidant vitamins may be of epidemiological significance in the early prediction and treatment of prostate complications. The study aimed to explore the serum trace elements, antioxidant vitamins concentration and serum prostate specific antigen (PSA) among male with prostate disorders in the delta region of Nigeria.Methods: Blood specimens were collected from males with symptoms of prostatitis (n=70), benign prostatic hyperplasia (BPH; n=60) and prostate cancer (PCa; n=70), alongside with apparently healthy male subjects (n=60). The levels of trace elements and antioxidant vitamins were evaluated. Fluorescence immunoassay technique was used to assess the expression of PSA. Results: Compared with the controls, PCa patients had a significantly increased level of vitamin A (p<0.05), however, no significant differences in the serum levels of trace elements and antioxidant vitamins between subjects with prostate disorders and control group (p>0.05). Interestingly, there was a significant positive correlation between prostate specific antigen, trace elements and vitamins in BPH group (p<0.05).Conclusions: Prostate disorders such as prostatitis, BPH and PCa may be associated with elevated levels of PSA, but, does not affect the circulating expression of some serum trace elements and antioxidant vitamins. ]]>
<![CDATA[Muscle Mass Difference among Patients With Chronic Kidney Disease Stage 3 to Stage 5 ]]>
<![CDATA[Ivena Ivena]]>;
<![CDATA[Rudi Supriyadi]]>;
<![CDATA[Setiawan Setiawan]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1505
<![CDATA[Background: Low muscle mass is one of the complications of chronic kidney disease (CKD), that may occur due to the accumulation of uremic toxins and other mechanisms related to CKD. The aim of this study was to explore the difference of muscle mass among CKD patients stage 3 to stage 5.Methods: A cross-sectional study was conducted with comparative analysis, using secondary data collected during the year 2017 by total sampling method. Subjects were patients aged over 18 years with CKD stage 3 to stage 5 from three hospitals in Bandung. Chronic Kidney Disease stages were determined based on Glomerular Filtration Rate. Muscle mass data was determined using Bioelectrical Impedance Analysis, collected from previous research. Data were analyzed usingone-way ANOVA or Kruskal-Wallis test.Results: One hundred subjects consisting of 57 men and 43 women were included in in this study with the mean muscle mass was 26.29%±4.86, of whom 67% of the patients had low muscle mass. There was no difference between male (27.21%±3.82) and female (28.36%±4.67). The muscle mass among patients withCKD stage 3 to stage 5 showed no significant results (p>0.05).Conclusions: There is no difference in muscle mass among CKD stage 3 to stage 5.]]>
<![CDATA[Malnutrition in Non-Hodgkin Lymphoma Patients at Dr. Hasan Sadikin General Hospital Bandung ]]>
<![CDATA[Azizah Puspitasari Ardinal]]>;
<![CDATA[Siska Wiramihardja]]>;
<![CDATA[Indra Wijaya]]>
<![CDATA[ Althea Medical Journal Vol 6, No 1 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n1.1521
<![CDATA[Background: Non-hodgkin lymphoma (NHL) has the highest prevalence among hematologic malignancies. The prognosis and response to therapy in NHL patients may worsen in the presence of malnutrition. The aim of the study was to describe the malnutrition status in NHL patients. Methods: This was a cross-sectional descriptive study. Nutritional status was assessed using Subjective Global Assessment (SGA) obtained from the medical records of all NHL patients at Dr. Hasan Sadikin General Hospital registered in 2017.Results: In total, there were 78 medical records of NHL patients that fulfilled the inclusion criteria. All NHL patients had experienced malnutrition, categorized as mild-moderate malnutrition (70.5%) and severe malnutrition (29.5%). In NHL patients with mild-moderate malnutrition, 29% had 5–10% weight loss; 60% had suboptimal solid diet; 56.4% experienced anorexia; and 50.9% had subcutaneous fat loss. In NHL patients with severe malnutrition, 78.3% had more than 10% weight loss; 73.9% had suboptimal solid diet; 78.3% experienced anorexia; and 100% had subcutaneous fat loss.Conclusions: Based on subjective assessment, all NHL patients were malnourished and experienced change of food intake and loss of subcutaneous fat, therefore, a better nutritional support scheme are crucial for NHL patients.]]>
