Althea Medical Journal
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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<![CDATA[Footwear Usage in Children with Flatfoot Disorder in Sukajadi Sub-district, Bandung ]]>
<![CDATA[Wulan Mayasari]]>;
<![CDATA[Elta Sholihah Putri]]>;
<![CDATA[Fathurachman Fathurachman]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1137
<![CDATA[Background: Flatfoot is a musculoskeletal disorder of the foot where the medial longitudinal arch becomes flatter, resulting in a more foot surface touching the ground compared to the normal foot. One of the risk factors for flatfoot is the rather early footwear usage with a considerably long period of usage with the enclosed footwear type. This may cause weakening of supporting tissues of the foot. This study aimed to describe the use of footwear in children with flatfoot.Methods: This study used a descriptive categorical method, conducted from March to June 2017 among students from five elementary schools in Sukajadi sub-district, Bandung. Primary data were obtained by using questionnaires and descriptively presented.Results: Prevalence of flatfoot among included students (n73) of the elementary school with age range of 6–10 years was 54.8%. All students had their first years of wearing footwear in the age range 0-5 years. The majority (52.5%) of footwear usage duration in flatfoot disorder was ≥8 hours/day, and the footwear type of flatfoot disorder was dominated (65%) by sandals/slippers.Conclusions: There is a high number of flatfoot in elementary school, and this needs special attention, especially on how to use the footwear. ]]>
<![CDATA[Antibacterial Effect of Jatropha multifida L. Leaf Infusion towards Staphylococcus aureus and Pseudomonas aeruginosa ]]>
<![CDATA[Ivan Ivan]]>;
<![CDATA[Sunarjati Sudigdoadi]]>;
<![CDATA[Achmad Hussein S. Kartamihardja]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1622
<![CDATA[Background: Jatropha multifida is one of the medicinal plants commonly found in Indonesia. This plant is used in the community to heal open wounds, however, scientific evidence is lacking. The two most common bacteria which often cause infection in open wounds are Staphylococcus aureus and Pseudomonas aeruginosa. This study aimed to determine the antibacterial effect of J. multifida leaf infusion towards S. aureus and P. Aeruginosa in vitro.Methods: This was an experimental laboratory study conducted at the Microbiology Laboratory, Faculty of Medicine, Universitas Padjadjaran in 2014. The modified Kirby-Bauer antimicrobial diffusion procedure on Mueller-Hinton agar was applied to determine the inhibitory zone. In determining the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC), the modified technique of tube dilution was used.Results: The results of this research showed that the infusion of J. multifida leaves had inhibitory effects on the growth of S. aureus dan P. aeruginosa at the concentration of 100% and 75%. The minimum inhibition concentration and minimum bactericidal concentration could not be determined.Conclusions: There is evidence confirming the bacteriostatic antibacterial effect of J. multifida leaves which inhibits the growth of S. aureus and P. Aeruginosa. Further study is needed to explore J. multifida leaves.]]>
<![CDATA[Cardiovascular Risk Profile in Health Cadres in Jatinangor, West Java ]]>
<![CDATA[Badai Bhatara Tiksnadi]]>;
<![CDATA[Rien Afrianti]]>;
<![CDATA[Yulia Sofiatin]]>;
<![CDATA[Arif Ridha]]>;
<![CDATA[Faris Yuflih Fihaya]]>;
<![CDATA[Rully M. A. Roesli]]>;
<![CDATA[Mohammad Rizki Akbar]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1529
<![CDATA[Background: Cardiovascular disease has very high morbidity and mortality, therefore, prevention of this disease becomes a national priority in the health programs. Health cadres, as an agent in community primary prevention, should have a good health condition. This study aimed to describe the cardiovascular risk profile in health cadresin Jatinangor, West Java.Methods: This was a cross-sectional study, conducted in Cilayung Village, Jatinangor, in September 2018. Consecutive sampling was performed on 20 health cadres aged 25 - 64 years old who did not have previous cardiovascular events such as coronary heart disease or stroke. Clinical data were collected consisting of blood pressure, body mass index (BMI), random blood glucose, history of diabetes mellitus, physical activity and active smoking habits. Cardiovascular risk was assessed using Jakarta cardiovascular scores and European Relative Risk Score.Results: Only 17 of 20 health cadres fulfilled the inclusion criteria with a systolic and diastolic blood pressure of 133.5±27.8 mmHg and 81.1±14.8 mmHg, respectively, and BMI of 27.4±5.3 kg/m2.The risk of cardiovascular disease in healthy cadres was at low (47.1%), moderate (41.2%) and high risk (11.7%). The average of the European Relative Risk score was 1.88±0.9. BMI >30 has a 40% high risk of cardiovascular disease.Conclusions: Most of the health cadres in Jatinangor, West Java have a low and moderate risk of cardiovascular disease, even though there is a small percentage that is at a high risk. The awareness for prevention and management programs for risk factors needs to be raised among health cadres. . ]]>
<![CDATA[Quality Of Life of Laryngeal Carcinoma Patients after Total Laryngectomy ]]>
<![CDATA[Achmad Prihadianto]]>;
<![CDATA[Yussy Afriani Dewi]]>;
<![CDATA[Agung Dinasti Permana]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1689
<![CDATA[Background: Management of laryngeal carcinoma has been widely developed, either by surgery, radiotherapy, and/or chemotherapy. The treatment has a major impact on physical, social, and psychological health that can change the quality of life of patients. This study aimed to determine the quality of life of laryngeal carcinoma patients after total laryngectomy.Methods: This descriptive study was conducted from May to August 2018. Patients with post total laryngectomy at the Division of Ear, Nose, Throat, Head and Neck Surgery, Dr. Hasan Sadikin General Hospital, Bandung were recruited. Short Form 36 (SF-36) Study Questionnaire and the European Organization for Research and Treatment of Cancer Head and Neck Cancer Quality of Life Questionnaire (EORTC QLQ-H & N35) were used, and data were presented in the form of descriptive narratives and tables.Results: In total, 23 patients were included consisting of 19 men (82.61%) and women (17.39%), aged 56-65 years old. The mean score of quality of life in physical components of SF-36 was 87.55 ± 2.35 and in mental components was 85.35 ± 3.92. The highest score of quality of life of EORTC QLQ-H & N35 on the speech problem scale was 51.69 ± 6.36. Conclusion: The quality of life of laryngeal carcinoma patients after total laryngectomy is generally good, however, speech is the main problem and needs to be further elaborated to enhance the quality of life.]]>
<![CDATA[Serum Calcium Levels in Chronic Kidney Disease Patient Stratified By Body Mass Index ]]>
<![CDATA[Anthoni Anthoni]]>;
<![CDATA[Rudi Supriyadi]]>;
<![CDATA[Siti Nur Fatimah]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1516
<![CDATA[Background: Most of the chronic kidney disease (CKD) patients have low blood calcium levels, yet hypercalcemia has a worse outcome in CKD patients. Interestingly, CKD patients with higher body mass index (BMI) have better outcomes. This study aimed to elucidate the difference in blood calcium levels stratified by BMI categories in patients with CKD.Methods: The study was conducted using a comparative analytical cross-sectional study design. Patients with CKD (n100), aged over 18 years old were included, Patients with the following were excluded: the history of hemodialysis, history of antioxidants, calcium and vitamin D supplement consumption, history of infection and malignancy. BMI of patients was categorized into underweight (<18.5 kg/m2), normal (8.5-22.9 kg/m2), and overweight or obese (≥23 kg/m2). Data were analyzed to compare blood calcium in different categories of BMI (Kruskal-Wallis test). Results: The age of patients with CKD included in this study had median age of 61 years old, predominantly was men (57%). The blood calcium level of CKD patients was on the lower border of the normal range. Median BMI was 23.48 kg/m2, of which 53% was categorized as overweight or obese. There was a trend that overweight/obese patients had higher blood calcium levels than underweight and normal-weight patients, however, no statistically significant difference between the BMI category (p=0.982).Conclusions: The blood calcium level in chronic kidney disease varies across the BMI category, however, no correlation with the BMI.]]>
<![CDATA[Annona Muricata L Leaf Infusion Effect on Glucose Absorption in the Intestinal Cells Membrane of Wistar Rats Model ]]>
<![CDATA[Vycke Yunivita]]>;
<![CDATA[Putra Haqiqie Adnantama Lubis]]>;
<![CDATA[Augusta Y. L. Arifin]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.509
<![CDATA[Background: Diabetes mellitus (DM) is a chronic disease that disrupts the homeostasis of glucose. DM is the second of most causes of deaths in urban areas, as well as the sixth in rural areas. Therefore, herbal medicine is constantly developed. Soursop leaves have been long known to have good effects in lowering glucose levels in our blood. This study explored the soursop leaves infusion on glucose absorption in the intestinal cell membrane of the Wistar Rats Model. Methods: This was an exploratory study performed in October 2012 on five male rats Wistar, aged 3-4 months, weighing about 150-300 grams. Using the in situ perfusion method, each rat was given the following; 3 X 10-3 M glucose solution for one hour; 3 X 10-3 M glucose solution with 1 mL of infusion of soursop leaves (Annona muricata L) for one hour; 3 X 10-3 M glucose solution for the last hour. The glucose absorption levels were measured using spectrophotometry method. The glucose level between treatments was analyzed using a paired sample t-test.Results: The concentration of glucose absorption was decreased, the first treatment was 24.42+14.29 mg/dL, the second treatment was 18.63+10.37 mg/dL, and the third treatment was 18.24+8.02mg/dL), however, the decrease of glucose absorption was statistically not significant.Conclusions: There is a slightly decreased of the glucose absorption in the intestinal cell membranes of the Wistar Rats Model after infusion of soursop leaves. Further study is needed to explore the role of soursop leaves infusion in glucose absorption.]]>
<![CDATA[Pharmacological Treatment Pattern and Comorbidities in Parkinson’s Disease Outpatients at Dr. Hasan Sadikin General Hospital Bandung in 2013–2018 ]]>
<![CDATA[Elke Feliciana]]>;
<![CDATA[Paulus Anam Ong]]>;
<![CDATA[Sobaryati Sobaryati]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1513
<![CDATA[Background: Parkinson’s disease (PD) is one of many neurodegenerative diseases with symptomatic management, and with the correct pattern of pharmacological treatment PD may have an improved quality of life for a minimum of three years. This study aimed to illustrate treatment patterns and comorbidities in PD patients at Dr. Hasan Sadikin General Hospital, Bandung.Methods: This study was a cross-sectional descriptive study by using total medical records of the period of 2013 to 2018. PD patients receiving pharmacological treatments such as levodopa, anticholinergics, dopamine agonists, or combined therapy were included. Patients with incomplete data and with the previous history of other neurological diseases before PD were excluded from this study.Results: In total, there were 57 patients with PD, of whom most of them were males (79%). Age-wise, PD was most common in 60 to 69-year-olds (32%). The most commonly used treatment pattern was the administration of levodopa (33%). Patients aged younger than 30 years were administered anticholinergics, whereas the older patients (>60 years old) mostly were given levodopa. Comorbidities after PD diagnosis were mostly stroke, dementia, and epilepsy.Conclusions: Males are most affected by PD, and the most commonly used treatment pattern is levodopa monotherapy. PD is most commonly found in patients aged 60 to 69 years. Patients aged below 30 years are administered anticholinergics. The most common comorbidities found are a stroke, followed by dementia and epilepsy. By recognizing the patterns and comorbidities of this disease, the study may provide some insights into choosing the most effective pharmacological therapy for PD. ]]>
<![CDATA[Parents’ Knowledge and Children’s Toilet Training Practices: Study in Kindergartens in Jatinangor ]]>
<![CDATA[Anne Shafira Purnama Claytonia Aziz]]>;
<![CDATA[Yudith Setiati Ermaya]]>;
<![CDATA[Nur Melani Sari]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1659
<![CDATA[Background: Constipation has serious threats for children, however, this condition can be treated by toilet training. The level of parents’ understanding of defecation affects the success of the training to reduce the symptom of constipation. This study aimed to assess the knowledge of the parents and their children’s practice in toilet training at kindergarten. Methods: This was an analytic study with a cross-sectional method which conducted at kindergartens in Jatinangor, selected by a total random sampling method. A self-made validated questionnaire was distributed to parents asking about knowledge and toilet training. Incomplete answer sheets and parents who did not come to school by the time of the study were excluded. Result: In total, 111 parents returned the questionnaire, and most of the parents (98.19%) had good knowledge regarding toilet training. Moreover, most of the children (96.39%) were also good at practicing the toilet training. There was a strong and significant correlation between parents’ knowledge and the children’s practice of toilet training with coefficient correlation 0.701 and p-value <0.05.Conclusions: Good knowledge of parents help the children practicing toilet training, therefore, education to new parents is necessary.]]>
<![CDATA[Clinical and Laboratory Manifestation of Children with Acute Lymphoblastic Leukemia as an Assessment of Severity: A Study in Dr. Hasan Sadikin General Hospital ]]>
<![CDATA[Yohana Kusuma Angkasa]]>;
<![CDATA[Nur Suryawan]]>;
<![CDATA[Delita Prihatni]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1528
<![CDATA[Background: Acute lymphoblastic leukemia (ALL) is a disease caused by a mutation of lymphoid progenitor cells in bone marrow, that induces uncontrolled lymphoid cell proliferation. ALL is the most common type of leukemia in children. Various clinical and laboratory manifestation makes the diagnostic process more complicated. This study aimed to observe the clinical and laboratory manifestation of children with ALL in Dr. Hasan Sadikin General Hospital for diagnostic and assessment.Methods: The design of this study was a descriptive cross-sectional with a total sampling method. Data of all children under 18 years old with ALL diagnosed in 2015 to 2017 were included. The diagnosis of ALL was confirmed by examination of hematology indices, peripheral blood smear, and bone marrow aspiration classified by FAB. Inaccessible or incomplete medical records were excluded.Results: In total, 192 data of ALL patients were included. Most ALL patients predominantly occurred in boys (59.9%), and the age group of 1–5 years old (40.6%). The clinical manifestations were pallor (89.6%), hepatomegaly (79.7%) and fever (75%). Most patients experienced severe anemia with hemoglobin level <7g/dL (44.8%), leukocytosis >20.000 cells/mm3 (46.9%), severe thrombocytopenia with platelet count <20.000 cells/mm3 (51%), and blast cells count >50% (45.3%). Based on FAB classification, the majority of the patients were classified as ALL type L2 (65.6%).Conclusions: Clinical and laboratory manifestation of ALL patients can be used as a parameter for diagnostic and assessment of severity. Earlier diagnosis would result in better prognosis and more precise treatment for ALL patients.]]>
<![CDATA[Correlation between Maternal Hemoglobin Level and Birth Weight ]]>
<![CDATA[Syifa Fauziyah Safithri]]>;
<![CDATA[Nia Kania]]>;
<![CDATA[Aly Diana]]>
<![CDATA[ Althea Medical Journal Vol 6, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/amj.v6n2.1637
<![CDATA[Background: Pregnant women are susceptible to have anemia, marked by hemoglobin level <11gr/dL. Maternal hemoglobin levels may influence the nutritional transfer, oxygenation, and uteroplacental circulation of the babies which may affect the infant’s birth weight. This study aimed to explore the correlation between hemoglobin level and birth weight in pregnant women in rural area in Bandung.Methods: This cross-sectional study was conducted from August to September 2014, recruiting all pregnant women registered in a hospital in a rural areas Bandung. Hemoglobin level was obtained from the medical records and analyzed to correlate with birth weight (Pearson correlation).Results: In total, there were 95 pregnant women included. The mean of maternal hemoglobin level was 11.6±1.2gr/dL and birth weight was 2.927±398gram. The proportion of maternal anemia and low birth weights were 30.5% and 15.8%, respectively. Pearson correlation test showed r=-0.093 and p=0.369 which was not significant.Conclusions: There was no correlation between maternal hemoglobin level and birth weight. Other factors for low maternal hemoglobin need to be further explored. ]]>
