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Tsania Faza
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08111400115
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mji@ui.ac.id
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Education Tower 6th floor, IMERI building, Faculty of Medicine Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia
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INDONESIA
Medical Journal of Indonesia
Published by Universitas Indonesia
ISSN : 08531773     EISSN : 22528083     DOI : 10.13181
Core Subject : Health,
This quarterly medical journal is an official scientific journal of the Faculty of Medicine Universitas Indonesia in collaboration with German-Indonesian Medical Association (DIGM) Indexed in: IMSEAR; CAB Abstracts; Global Health; HINARI; DOAJ; DRJI; Google Scholar; JournalTOCs; Ulrichsweb Global Serial Directory; WorldCat; New Jour; Electronic Journals Library; ISJD Accredited (2013-2018) by DIKTI Kemendikbud Republik Indonesia (No:58/DIKTI/Kep/2013)
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Articles 1,648 Documents
Role of general practitioner in the management of acute myocardial infarction
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.199

Abstract

Acute myocardial infarction (AMI) has been the leading cause of death in Western countries, as well as in Indonesia. Delay in diagnosis and incorrect early management often result in failure of thrombolytic reperfusion. General practitioner (GP) as the primary care, needs to be equipped with the ability to diagnose and moreover to manage AMI. A case of fail thrombolytic management in a 47 years old man after seven hours of angina typical chest pain, after previously managed by GP, is being reported. (Med J Indones 2005; 14:249-52)
Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.200

Abstract

Non Steroidal Anti Inflammatory Drugs (NSAID) have been associated with a sudden and sustained rise in the incidence of gastrointestinal ulcer complications. The aim of the study was to reveal the endoscopical abnormalities found in the duodenum & proximal jejunum due to NSAID. Thirty eight patients taking NSAID for their arthritis or rheumatism were included in this study. Gastro-duodeno-jejunoscopy was done with Olympus PCF-10. The endoscopical appearances of NSAID entero gastropathy were evaluated with a scoring system. The NSAID-entero-gastropathy appearances were endoscopically seen as hyperemia, erosion and ulcer. From all patient recruited, 7.9% complaint of diarrhea and 71.1% complaint of dyspepsia. Endoscopically, in the duodenal bulb we found 79% cases of hyperemia, 39.5% cases of erosion and 7.9% cases of ulcer. In the second part (descending part) of the duodenum we found 28.9% cases of hyperemia, 15.8% cases of erosion and 2.6% case of ulcer. In the jejunum, we found 7.9% cases of hyperemia, 2.6% case of erosion and no ulcer. It is concluded that the most frequent abnormal endoscopical appearances in NSAID- enteropathy was hyperemia. The most frequent site of NSAID-enteropathy abnormal findings was in the duodenal bulb. (Med J Indones 2005; 14: 225-9)
QT dispersion, a simple tool to predict ventricular tachyarrhythmias and/or sudden cardiac death after myocardial infarction
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.201

Abstract

Recent studies showed contradictive results of the relation between QT dispersion and the occurrence of ventricular tachyarrhythmias and/or sudden cardiac death. In addition, beta adrenoreceptors blocking agents, which are known to decrease the incidence of lethal arrhythmias after myocardial infarction, administered to the majority of patients in those studies population. Since β-blocker as secondary prevention drug was underutilized at National Cardiovascular Center Harapan Kita, this study was performed to find out the relation between QT dispersion and ventricular tachyarrhythmias and/or sudden cardiac death after previous myocardial infarction. The QT interval duration, QT dispersion and clinical variables of 36 postinfarction patients with history of sustained ventricular tachyarrhythmias and/or sudden cardiac death (event group) were compared with 75 postinfarction patients without such events (control group). QT dispersion differed significantly between study groups and was increased in the event group (115 ± 41 msec vs 81 ± 25 msec, p < 0.001). Corrected maximal QT interval duration was also prolonged in the event group (534 ± 56 vs 501 ± 35 msec, p < 0.001). Regression analysis showed that increasing QT dispersion was related to the occurrence of ventricular tachyarrhythmias and/or sudden cardiac death with OR of 3.2, 4, and 5.8 for cut-off point of 80, 90, and 100 msec respectively. The QT dispersion could predict the occurrence of ventricle tachyarrhythmias and/or sudden cardiac death in patient with AMI. This study confirmed that the QTd remain useful in free of beta blocking agents state. (Med J Indones 2005; 14: 230-6)
The effects of balanced low calorie diet on body composition and serum leptin of obese women
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.202

Abstract

The effect of balanced low-calorie diet for 14 days on body weight (BW), body mass index (BMI), total skin fold thickness (SFT), fat mass (FM), fat free mass (FFM), waist to hip ratio (WHR) and serum leptin level was evaluated by using a pre and post-experimental balanced low-calorie diet 915.23 kcal/day with the composition of 55.81% carbohydrate, 19.46% protein and 24.73% fat for 14 days on 39 obesewomen subjects (19-55 years old) who have met the inclusion and exclusion criteria. The collected data include demographic characteristic, macronutrient and energy intake, as well as of anthropometry, FM, FFM, and serum leptin level. Body weight reduction occurs significantly (p<0.05) from 70.99 ± 8.62 to 68.81 ± 8.36 kg (3.07%); BMI reduction is significant (p<0.05) from 30.28 ± 3.11 kg/m2 to 29.36 ± 2.94 kg/m2 (3.04%); Significantly reduced SFT (p<0.05) from 99.36 ± 12.07 mm to 91.29 ± 10.85 mm (8.08%); Significantly reduced FM (p<0.05) from 35.41 ± 2.75 % to 33.65 ± 2.73% (1.76%); Significantly increased FFM percentage (p<0.05) from 64.59 ± 2.74 to 66.35 ± 2.73 (2.72%); Significantly reduced WC (waist circumference) (p<0.05) from 85.87 ± 7.31 to 83.35 ± 7.09 (2.93%); Significantly reduced HC (hip circumference) (p<0.05) from 107.59 ± 6.67 to 106.49 ± 6.37 (1.02%); Significantly reducedWHR (p<0.05) from 0.80 ± 0.05 to 0.78 ± 0.04 (2.24%); Significantly reduced serum leptin (p<0.05) from 23.31 (12.06-71.22) to 18.18 (7.90-65.11) (22.01%); positive correlation is observed between serum leptin level and FM significantly (p<0.05) before treatment (r=0.47 ; p=0.003) and after treatment (r=0.57 ; p=0.001). Balanced low-calorie diet may effectively reduce body weight, BMI, skin fold thickness, percentage of fat mass, to increase percentage of fat free mass, to reduce waist to hip ratio and serum leptin level. (Med J Indones 2005; 14: 220-4)
Fatty acids intake among diverse ethnic groups in Indonesia
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.203

Abstract

The use of dietary pattern specifically fatty acids intake should prove to be an informative and powerful means to augment our understanding of the role of diet in chronic disease particularly CHD. Cross sectional study was implemented to describe the nutrients intake specifically fatty acids intake of 4 (four) ethnic groups in Indonesia, such as Minangkabau, Sundanese, Javanese and Buginese. The percentage of saturated fatty acid (SAFA) to total energy intakes were around 20%. The percentage of polyunsaturated fatty acid (PUFA) to the total energy were about 4.4% to 4.6% among the Sundanese and the Javanese.While among the other two ethnic groups, the percentage of PUFA to total energy were less, 2.6 % among the Minangkabau and 2.8% among the Buginese ethnic. The percentage of mono unsaturated fatty acid (MUFA) to total energy intake were higher among the two ethnic groups, Sundanese and Javanese (6.1% vs. 5.5%). While the percentages of MUFA between the other two ethnic groups Minangkabau and Buginese ethnic were lower (2.6% vs. 2.8%). Based on the ratio of PUFA: MUFA: SAFA, we could consider that Minangkabau and Buginese ethnic groups both had poor quality of dietary fat pattern. Having the poor quality of dietary fat pattern and higher fat intake, we might take into consideration that the Minangkabau ethnic groups, had higher risk toward dyslipidemia compared to the other three ethnic groups. (Med J Indones 2005; 14:242-8)
PM10 as Predictor of Ventilation Efficiency of Houses in Relation to Health Effect
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.204

Abstract

Concerns for the high concentration of particulates in the ambient air of Jakarta had been associated with respiratory health effects. Accordingly, the high concentration of indoor air particulate in homes was also recognized as a potential health hazard to the household. This paper was based on findings in a cross-sectional study in homes of a village, Jakarta done for a dissertation of a doctoral degree in Public Health. In relation to health aspect, ventilation effectiveness was more predicted by the variation of indoor particulates concentrations (as PM10) than the physical characteristic of the houses. Besides, respiratory symptoms rates among children under-five were positively associated to PM10 concentrations. Except for the house dampness factor, no physical features of the houses such as sizes of windows, rooms, and the like, contributed to the variability of health of the occupants. This research suggested that PM10 concentration was a better indicator for a healthy house than the physical characteristics of the house. As such, the most sensitive and specific level of PM10 concentration to predict the development of respiratory symptoms was 70 µg/m3. This cut-off concentration of PM10 agreed with the guideline value set on the level of 70 µg/m3 for the thoracic particles by the World Health Organization. (Med J Indones 2005; 14: 237-41)
The benefits of progesterone therapy in imminent abortion
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.205

Abstract

The causes of imminent abortion are multi-factorial. The biggest causal factor is the low level of serum progesterone level. The lowest critical level of serum progesterone for survivability of pregnancy is 10 ng/ml. Eighty percent of patients experiencing abortion showed that their progesterone level was < 10 ng/ml. Patients who realized that their pregnancy would experience hemorrhage generally would suffer from depression. Stress was one of the factors responsible for the occurence of abortion. Administration of natural progesterone substitution (not progestogen) accelerates the disappearance of uterine contractions, and speeds up the stoppage of bleeding. In addition, progesterone has the effect of anti-anxiety. Adminstration of oral progesterone would result in metabolism in the intestine and liver, such that physiological level of serum progesterone could not be reached, while administration of suppositoria progesterone would result in physiological level of serum, such that it was effective to prevent imminent abortion. (Med J Indones 2005; 14:258-62)
Treatment of taeniasis and cysticercosis with praziquantel and albendazole
Medical Journal of Indonesia Vol. 14 No. 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i4.206

Abstract

Recent methods, doses and results of medical treatment on taeniasis/cysticercosis, a zoo-notic parasitic disease caused by Taenia solium and Taenia saginata are discussed. In cases of cysticercosis T. solium, especially neurocysticercosis the optimal length and dose of albendazole is a course of 8 days with doses of 15 mg/kg/day divided in two times added by 50 mg/day of prednisone in the morning. The drug is effective in almost any location of the parasites for 80-90% of macroscopic cysts seen by imaging studies. For taeniasis a single dose of praziquantel, 10-15 mg/kg achieves cure rates of more than 90%. Side effects such as nausea, headache and abdominal pain are mild. Evaluation of drug treatment is done by clinical, radiological and serological evaluation. In Papua (=Irian Jaya) nine cases with suspected neurocysticercosis, serologically positive, were treated with 1200 mg single dose albendazole for 15 days. Prednisone tablets, three times daily one tablet, 5 mg during 7 days were added. After one year 6 cases were still serologic positive. At the same time praziquantel, 1200 mg, single dose was given to ten cases during 15 days and prednisone tablets, 3 times daily one tablet, 5 mg during 7 days. After one year 5 sero-positive cases were still found. Albendazole and praziquantel are both effective drugs for taeniasis and cysticercosis, with minor side effects. In addition symptomatic treatment should be given if necessary. (Med J Indones 2005; 14:253-7)
Comparison of efficacy combination of inhaled phormoterol / budesonide turbuhaler vs. combination of nebulized salbutamol / ipratropium bromide on moderate asthma acute exacerbation in Persahabatan Hospital
Medical Journal of Indonesia Vol. 15 No. 1 (2006): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v15i1.207

Abstract

The aim of this study was to compare efficacy combination of phormoterol/budesonide turbuhaler vs. salbutamol/ipratropium bromide nebulization. Main therapy for acute asthma is inhaled short acting β2-agonist. Asthma patients are using two drugs, controller and reliever. Recently there is device-containing combination of long-acting β2-agonist with rapid onset and corticosteroid. This combination can act as reliever and controller. An opened randomized clinical trial of 76 patients between the ages of 12 and 60 years presenting to Persahabatan Hospital with asthma score between 8-12 participated in this study. After initial evaluation, patients were divided into two groups. Thirty-eight patients were administered combination of formoterol/budesonide 4.5/160 µg via turbuhaler (T-group) every 20 minutes, total of three doses, and another 38 of salbutamol/ipratropium bromide 2.5/0.25 mg via nebulizer (N-group) also with the same manner. There were no statistical difference in sex, mean age, high, weight, initial PEFR, and asthma score between two groups. The significant increased of PEFR and decreased of asthma score were observed in both groups. However, there were no significant difference of PEFR and asthma score between the two groups within every time-interval. Adverse events were mild including hoarseness, tremor and palpitation. Of T-group, 1 subject was suffered from 3 adverse events simultaneously (hoarseness, tremor and palpitation), 5 subjects were only tremor. Of N-group, all 6 subjects were only suffered from tremor. A combination of formoterol/budesonide turbuhaler and a combination of nebulized salbutamol/ipratropium bromide are clinically equivalent for treatment moderate acute asthma. However, nebulized salbutamol/ipratropium bromide had less adverse effects. (Med J Indones 2006; 15:34-42) Keywords: phormoterol, budesonide, salbutamol, ipratropium bromide, acute asthma
Laparoscopic resection versus myolysis in the management of symptomatic uterine adenomyosis: alternatives to conventional treatment
Medical Journal of Indonesia Vol. 15 No. 1 (2006): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v15i1.208

Abstract

Effective therapy preserving reproductive function in adenomyosis is warranted. From June 2003 to June 2004, patients diagnosed as having adenomyosis by transvaginal ultrasound and had symptoms of menorrhagia, dysmenorrhea, and pelvic pain were randomly allocated to either receive laparoscopic resection or myolysis. GnRH analog was given for 3 cycles after surgery. Within 6 months, symptoms were evaluated using questionnaires and at the end of follow up, adenomyosis volume was assessed by transvaginal ultra-sound. There were 20 patients included, 10 patients had resection and the rest underwent myolysis. Both procedures did not yield sig-nificant complications. Subjective evaluation by questionnaires was done in all patients. Three patients could not be evaluated objec-tively by transvaginal ultrasound, 2 patients resigned and 1 was pregnant. There was no significant difference in menorrhagia and dysmenorrhea reduction score between the 2 groups (p=0.399 and 0.213, respectively). In both groups, dysmenorrhea was reduced significantly after treatment. No significant statistical difference was found in median adenomyosis volume increment (p=0.630) be-tween the resection (median=+15.35% (-100-159)} and myolysis groups (median=+48.43% (-100-553)). Five patients were pregnant, 3 from the resection group and 2 from the myolysis group. Uterine rupture was found in 1 patient (from the myolysis group) at the age of 8 months of pregnancy. The effectiveness of laparoscopic adenomyosis resection was not significantly different compared with lapa-rascopic myolysis as an alternative conservative surgery in treating symptomatic adenomyosis. Myolysis was not recommended for women who wish to be pregnant. (Med J Indones 2006; 15:9-17)Keywords: laparascopy, resection, myolysis, conservative surgery, symptomatic adenomyosis

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