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INDONESIA
Indonesian Journal of Urology
Published by Universitas Airlangga
ISSN : 0853442X     EISSN : 23551402     DOI : 10.32421
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The aim of Indonesian Journal of Urology is to encompass the whole spectrum of urology. The journal publishes papers on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, pediatric urology, and sexual medicine. We welcome authors for original article (research), review article, interesting case reports, special article, clinical practices, and medical illustrations that focus on the clinical area of urology.
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Articles 498 Documents
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HUBUNGAN ORKIDEKTOMI DAN DETORSI DENGAN RESPON IMUN TESTIS KONTRALATERAL PADA TORSIO TESTIS Ongkorahardjo, Edwin; Hardjowijoto, Sunaryo; Soetojo, Soetojo
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.361

Abstract

Objective: In attempt to explain effects of orchiectomy and detorsion in contralateral testis immune response after unilateral testicular torsion. Materials and methods: Forty eight rattus norwegicus strain wistar white rats testes underwent 720º unilateral left testicular torsion. The experimental animals were divided into 6 group: 2 had sham operation which served as control, 2 groups had ligation left testicular torsion with subsequent orchiectomy at 4 and 24 hours, 2 groups had ligation left testicular torsion followed by detorsion at 4 and 24 hours. Contralateral testes were analyzed 7 days later for examination percentage of IL-4 producing lymphocyte and immunoglobulin G producing plasma cells in contralateral testis by means of immunohistochemical method. Results: Multivariate analysis result revealed that in unilateral left testicular torsion followed by detorsion at 24 hours group we found IL-4 and IgG had entered intratubules and were different from orchiectomy and control group (p=0,0001 and p=0,0001). This indicated damage of germinal epithelium in contralateral testes caused by imunologic response stimulated by detorsion. In left testicular torsion and orchiectomy or detorsion at 4 hours did not show both IL-4 and IgG in intratubules and no significant different both IL-4 and IgG in extratubules among orchiectomy, detorsion and control group (p=0,326 and p=0,064). This indicated that in 4 hours immune response were not significantly different between those groups and germinal epithelium were still intact. Conclusion: Detorsion in 24 hours testicular torsion had stimulated immune response which caused damage of germinal epithelium in contralateral testis. In 4 hours testicular torsion immune response happened not significantly different between detorsion, orchiectomy and control.
PENGETAHUAN, TINGKAH LAKU, DAN TINDAKAN KLINIS DOKTER UMUM PADA PENATALAKSANAAN BPH Adi, Kuncoro; Safriadi, Ferry; Sugandi, Suwandi; Haroen, Zulhardi; Noegroho, Bambang S; Tjahjodjati, Tjahjodjati
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.362

Abstract

Objective: To evaluate the Primary Care Physician’s (PCPs) knowledge, attitude and clinical behavior in managing patients with BPH, as an input in the review of BPH guideline of Indonesian Urology Association. Material & method: The mailing included a cover letter, questioner consist of 10 questions survey, survey instrument and a post-paid envelope. A 10-questions survey were validated according to BPH guideline by Indonesian Urology Association (IUA). PCPs who work in district health offices and registered in district health office of Indonesian Health Ministry in Bandung, were selected as respondents. Results: 75% of sampled primary care physician working in 71 district health offices responded. 83% of respondent did not know the BPH guideline that had been published by Indonesian Urology Association. Although 88% of PCP’s knew about the symptoms of BPH, only 32% heard about of International Prostate Symptoms score. However, only 13 % were reported applying the symptoms score. Regarding to mandatory examination by the guideline, 64% of PCPs reported performing digital rectal examination, and 47% reported ordering urinalysis test. The recommended test such as PSA and serum creatinine level only asked 24% and 60% by PCPs. Only 21% of PCPs knew about the uroflowmetry but never ordering the test. 47% of PCPs reported using α blockers and 2% using finasteride for treating BPH. The referral was conducted by PCPs mostly due to urinary retention and hematuria. 70% of PCPs would refer the patients to urologist and the others to general surgeon and general internist. Conclusion: Although PCPs play role up to certain extent in diagnosing and managing of BPH, most of them are not interested in looking for reference.
PENGARUH ISKEMIA TERHADAP PENINGKATAN KOLAGEN PADA KORPUS KAVERNOSUM Alif, Sabilal
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.363

Abstract

Objective: To demonstrate that ischemia causes elevation of collagen in cavernous body. Material & Method: Sample used in this study were male adult rabbits (Oryctalagus Cuniculus) 6 – 9 months of age. Partial ligation of both common iliac arteries was performed in this study to induce cavernous body ischemia. Results: Collagen mean for 7 x 24 hours ligation group (group B) increased to 113,83/200 compared to the collagen mean for the 2 x 24 hours ligation group (group A) which was 91,08/200 and collagen mean for control group (group C) which was 86,90/200. There was collagen elevation on treatment group which caused by ligation (Anova, F value= 12,110 and p=0,0001). Conclusion: Ischemia may elevate collagen in cavernous body. 
PERBANDINGAN DAN PENYEBARAN ESCHERICHIA COLI DAN KLEBSIELLA PNEUMONIAE PENGHASIL EXTENDED SPECTRUM BETA-LAKTAMASE PADA ISOLAT URINE PASIEN PRIA DENGAN KATETER DAN TANPA KATETER Husada, Satrya; Hardjowijoto, Sunaryo; Gardjito, Widjoseno
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.364

Abstract

Objective: membandingkan dan menelaah penyebaran bakteri Eschericchia coli dan Klebsiella pneumoniae penghasil ESBL pada pasien dengan kateter dan tanpa kateter. Material & methods: Sampel dalam penelitian ini adalah 194 orang pasien di bagian urologi RSU Dr. Soetomo Surabaya Yang memenuhi criteria inklusi, yang dibagi dalam 2 kelompok secara random. Sembilan puluh tujuh orang pasien dipasang kateter dan 97 orang yang lain tidak dipasang kateter. Bakteri yang diteliti adalah Eschericchia coli dan Klebsiella pneumoniae yang menjadi resisten akibat peran ESBL. Semua hasil kultur urine diperiksa dan dicatat. Results: Didapatkan Persentase kejadian E. coli pada pasien yang dipasang kateter lebih tinggi dibandingkan yang tidak dipasang kateter, yaitu 51,2% : 48,8%, sedangkan persentase kejadian K pneumonia pada pasien yang dipasang kateter lebih rendah dibandingkan yang tidak dipasang kateter, yaitu 45,5% : 54,5%. Persentase ESBL negatif pada pasien yang dipasang kateter lebih rendah dibandingkan yang tidak dipasang kateter, yaitu 38,9% : 61,1%, sedangkan persentase ESBL positif pada pasien yang dipasang kateter lebih tinggi dibandingkan yang tidak dipasang kateter, yaitu 72,2% : 27,8%. Persentase penyebaran E. coli dibandingkan K. pneumonia lebih tinggi pada E. coli, yaitu 34,9% : 27,3%. Conclusion: Tidak ada perbedaan penyebab kejadian infeksi oleh kuman E. Coli dan K. Pneumoniae pada pasien dengan kateter dan tanpa kateter. Angka kejadian E. coli dan K. pneumoniae penghasil ESBL pada pasien pemakai kateter lebih tinggi daripada pasien pria tanpa kateter di bagian urologi. Adanya penyebaran klonal E. coli dan K. pneumoniae penghasil ESBL dari pasien satu ke pasien urologi lain.       
ANGKA KEBERHASILAN DAN KOMPLIKASI PCNL PADA PASIEN BATU GINJAL DI RUMAH SAKIT CIPTO MANGUNKUSUMO TAHUN 1999 – 2006 Murti, Bimanggono Hernowo; Rasyid, Nur
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.365

Abstract

Objective: To study the results of renal stones treatment with PCNL in terms of complication and stone free rate in Cipto Mangunkusumo Hospital. Material & methods: Retrospective study of renal stone patients who were treated with PCNL at the Department of Urology, Cipto Mangunkusumo Hospital from January 1st 1999 until May 31st 2006. Results: There were 213 patients between 8 until 80 years old done for various stone localizations in the kidney. The overall stone free rate was 74,2%. The complication rate was 10,8%, bleeding in 15 patients (7,1%), leakage in 5 patients (2,3%), and colon perforation in 3 patients (1,4%). There was no artery + vena renalis perforation, urosepsis, hydro/pneumothorax or mortality in this group. Results are similar with experience in the literature. Conclusion: PCNL is a safe procedure for renal stones removal. It gives satisfactory results as well as a low complication rate, but if complications occur the morbidity can be severe. Hence, this procedure has to be done very meticulously.
ULTRASONOGRAFI UNTUK PREDIKSI LASERASI PARENKIM GINJAL DAN HEMATOMA PERIRENAL PADA PASIEN TRAUMA TUMPUL ABDOMEN DENGAN KECURIGAAN TRAUMA GINJAL Richata, Galuh; Sugandi, Suwandi; Haroen, Zulhardi; E, Mumuh M; Noegroho, Bambang S; Tjahjodjati, Tjahjodjati; Safriadi, Ferry
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.366

Abstract

Objective: To evaluate the sensitivity and the specificity of the ultrasound in predicting renal parenchyma laceration and perirenal hematoma in patients with abdominal blunt trauma with suspicion of renal trauma, as confirmed by operative findings in the explorative laparotomy. Material & methods: From March 2005 to March 2006, we found 28 patients admitted to the emergency department with abdominal blunt trauma with suspicion of renal trauma. Every patient was scanned sonografically to detect the presence of the renal parenchyma laceration and perirenal hematoma. All those patients underwent laparotomy for any certain indication, but not because of ultrasound findings. The ultrasound findings then were checked with the operative findings. Results: The sensitivity of the ultrasound in predicting renal parenchyma laceration is 53.8%, while its sensitivity in predicting perirenal hematoma is 75%. The specificity of ultrasound in predicting both renal parenchyma laceration and perirenal hematoma is 100%. Conclusion: Ultrasound for kidney trauma is sensitive in predicting the presence of perirenal hematoma, but not sensitive in predicting the presence of a renal parenchyma laceration. Ultrasound is very specific in predicting if both perirenal hematoma and renal parenchyma laceration are present.
PROSTATE CANCER RISK CALCULATOR COMPARISON: IPCRC vs KPCRC vs PCPT-RC vs ERSPC-RC IN PREDICTING PROSTATE CANCER AT HASAN SADIKIN HOSPITAL Tansol, Christiano; Safriadi, Ferry
Indonesian Journal of Urology Vol 24 No 2 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i2.368

Abstract

Objective: To compare the validated calculators of Indonesian Prostate Cancer Risk Calculator  (IPCRC) vs Korean Prostate Cancer Risk Calculator (KPCRC) vs Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) vs European Randomized Study of Screening for Prostate Cancer Risk Calculator (ERSPC-RC) in predicting prostate cancer in our patients at Hasan Sadikin Hospital Bandung. Material & methods: This study is a prospective study conducted from August 2014 – December 2015 at Urology Clinic at Hasan Sadikin Hospital that included all patients with BPH or suspected PCa who have been undergoing prostate biopsy. Variables such as age, PSA level, prostate volume (transabdominal or transrectal ultrasound) and digital rectal examination (DRE) finding were recorded. Risk calculation was generated using each risk calculator. Data were analyzed using Chi-square analysis, Kolmogorov-Smirnov, and finally receiver operating characterisitic (ROC) curve. All statistical analyses were performed with SPSS version 20.  Results: There were 89 BPH and 43 PCa patients between August 2014 – December 2015. The mean age, PSA and prostate volume are 65.78 ± 8.33 years; 121.16 ± 375.76ng/ml; 55.86 ± 31.9ml respectively. Abnormal DRE was found in 27 PCas and 4 BPHs. Receiver operator curve analysis of IPCRC showed AUC 0.861 vs KPCRC (AUC=0.779) vs ERSPC-RC (AUC=0.745) vs PCPT-RC (AUC=0.794) vs PSA (AUC 0.794), sensitivity 81.4% and specificity 71.9% with cut-off point 19.67 for the IPCRC in predicting the prostate cancer in our center. Conclusion: IPCRC is better than KPCRC, PCPT-RC and ERSPC-RC in predicting prostate cancer in our center.
EFFICACY AND SAFETY OF LUBRICATING JELLY INSTILLATION TO PREVENT RETROPULSION DURING URETEROLITHOTRIPSY FOR URETERAL STONES Yuanda, Rameshdo; Soebadi, Doddy M; Soetojo, Soetojo; Hardjowijoto, Sunaryo
Indonesian Journal of Urology Vol 24 No 2 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i2.377

Abstract

Objective: We studied the efficacy and safety of lubricating jelly instillation before ureterolithotripsy for prevention of retropulsion and improvement in stone-free rate. Material & methods: We enrolled 22 subjects with ureteral stone in this prospective, randomized, single-blind and controlled clinical trial. Each subject was randomly assigned to the lubricating jelly instillation group (n=11) and control group (n=11). Ureteroscopy and lithotripsy was performed according the standard protocol, using 9.8 F semirigid ureteroscope and pneumatic lithotripter. A 6 F ureteral catheter was advanced beyond the stone, and lubricating jelly was instilled through the catheter lumen. Retropulsion and the presence of residual fragments were evaluated with plain kidneys, ureters and bladder x-ray and ultrasonography, or Non Contrast-enhanced Computed Tomography. Any complication was reported and graded using the Modified Clavien Classification System.Results: The 2 groups had comparable preoperative characteristics. There were no statistically significant difference between the lubricating jelly instillation group and control group regarding the retropulsion rate (54.5% vs 72.7%, ρ=0.375), the stone-free rate (54.5% vs 36.4%, ρ=0.392), and the complication rate (45.5% vs 54.5%, ρ=0.670). Conclusion: Lubricating jelly instillation during ureterolithotripsy has limited value for prevention of retropulsion and improvement in stone-free rate.
RELATIONSHIP OF PERIURETHRAL FIBROTIC IN BPH PATIENT WITH LUTS AND URINARY RETENTION Zamroni, Zamroni; Hardjowijoto, Sunaryo; Soetojo, Soetojo
Indonesian Journal of Urology Vol 24 No 2 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i2.378

Abstract

Objective: Analyzing the differences between collagen thicknesses in periurethral region from transurethral resection of the prostate (TURP) specimens of Benign Prostate Hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS) and of those with urinary retention. Material & methods: This was an observation analytic study on 30 patients who underwent TURP. Patients who met the inclusion criteria were divided into 2 groups: BPH patients with LUTS and those with urinary retention. Each group consisted of 15 people. The first TURP specimen of proximal verumontanum resection were examined in anatomic pathology using mass on strichrome staining as an examination of periurethral collagen thickness. Collagen will be stained as blue. Periurethral collagen thickness was measured from the basal membrane of transitional epithelium to fibromuscle tissue. Data were then statistically analyzed using independent t-test. Results: The average patient age was 66 ± 7 years old and there was no significant difference between age and periurethral collagen thickness with p=0.175 (p>0.05). The mean prostate volume was 47.19 ± 13.2 ml and there was no significant difference between prostate volume and periurethral collagen thickness with p=0.148 (p>0.05). Average periurethral collagen thickness in BPH patients with urinary retention was 146.67 ± 39.80 micrometers and while in those with LUTS was 205.33 ± 85.6 micrometers. There were no significant differences between periurethral collagen thickness and the occurrence urinary retention with retention of urine with p=0.063 (p>0.05). Conclusion: There were no significant differences between periurethral collagen thickness patients in BPH patients with LUTS and in those with urinary retention. This suggests that periurethral collagen thickness is not associated with the occurrence of urinary retention or LUTS in BPH patients.
THE EFFECT OF COMBINED α1-ADRENERGIC BLOCKERS AND PDE-5 INHIBITORS THERAPY ON IPSS, IIEF-5, QMAX AND PVR PATIENTS BPH WITH LUTS AND ERECTILE DYSFUNCTION Ridha, Muhammad; Hardjowijoto, Sunaryo; Renaldo, Johan
Indonesian Journal of Urology Vol 24 No 2 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i2.379

Abstract

Purpose: Assess the efficacy of combined α1-adrenergic blocker (tamsulosin 0,4 mg) and PDE5 inhibitor (tadalafil 5 mg) therapy compared to tadalafil or tamsulosin alone in treating patient BPH with LUTS and ED. Material and methods: A randomised, double blind experimental study assessed 36 sexually active men with ED and LUTS suggestive of BPH.  All patients were randomized to 3 groups: tamsulosin 0,4 mg (n=12), tadalafil 5mg (n=12), and combination of tamsulosin 0,4 mg and tadalafil 5 mg (n= 12), once daily for 6 weeks.  Changed in IPSS scores and QoL index, IIEF-5 scores, Qmax, PVR and blood pressure were assessed and compared to baseline. Complication and serious adverse event were also monitored.  Outcomes were assessed using ranked analysis of variance (ANOVA) and Kruskall-Wallis depends on data distribution and homogenity.Results:  Tamsulosin 0,4 mg once daily for 6 weeks were significantly improved IPSS score and QoL index and Qmax from baseline.  Tadalafil 5 mg once daily for 6 weeks were significantly improved IPSS score, QoL index and IIEF-5 index from baseline. Combined tamsulosin and tadalafil therapy were significantly improved IPSS score, QoL index, IIEF-5 index and Qmax from baseline.  Significantly better improvement on IIEF-5 dan Qmax from baseline were observed on the combination of tamsulosin and tadalafil compared to monotherapy with tamsulosin or tadalafil after 6 weeks in  patients BPH with LUTS and erectile dysfunction. There was no significant decreased in systolic and diastolic blood pressure from combined treatment compared to single treatment.Conclusions: Combined tamsulosin and tadalafil therapy was significantly better in improving IIEF aObjective: Assess the efficacy of combined α1-adrenergic blocker (tamsulosin 0.4 mg) and PDE5 inhibitor (tadalafil 5 mg) therapy compared to tadalafil or tamsulosin alone in treating patient Benign Prostate Hyperplasia (BPH) with lower urinary tract symptom (LUTS) and erectile dysfunction (ED). Material & methods: A randomised, double blind experimental study assessed 36 sexually active men with ED and LUTS suggestive of BPH. All patients were randomized to 3 groups: tamsulosin 0.4 mg (n=12), tadalafil 5mg (n=12), and combination of tamsulosin 0.4 mg and tadalafil 5 mg (n= 12), once daily for 6 weeks. Changed in IPSS scores and QoL index, IIEF-5 scores, Qmax, PVR and blood pressure were assessed and compared to baseline. Complication and serious adverse event were also monitored. Outcomes were assessed using ranked analysis of variance (ANOVA) and Kruskall-Wallis depends on data distribution and homogenity. Results: Tamsulosin 0.4 mg once daily for 6 weeks were significantly improved IPSS score, QoL index and Qmax from baseline. Tadalafil 5 mg once daily for 6 weeks were significantly improved IPSS score, QoL index and IIEF-5 index from baseline. Combined tamsulosin and tadalafil therapy were significantly improved IPSS score, QoL index, IIEF-5 index and Qmax from baseline. Significantly better improvement on IIEF-5 dan Qmax from baseline were observed on the combination of tamsulosin and tadalafil compared to monotherapy with tamsulosin or tadalafil after 6 weeks in  patients BPH with LUTS and erectile dysfunction. There was no significant decreased in systolic and diastolic blood pressure from combined treatment compared to single treatment. Conclusion: Combined tamsulosin and tadalafil therapy was significantly better in improving IIEF and Qmax, but not significantly better in improving IPSS and PVR compared to monotherapy with tamsulosin or tadalafil alone. Combined therapy was well tolerated without serious adverse effect.nd Qmax, but not significantly better in improving IPSS and PVR compared to monotherapy with tamsulosin or tadalafil alone.  Combined therapy was well tolerated without serious adverse effect.

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