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INDONESIA
Program Kreativitas Mahasiswa - Penelitian
Published by DITJEN DIKTI KEMDIKBUD RI
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Articles 66 Documents
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Search results for , issue " PKM-P 2013" : 66 Documents clear
LIMBAH KULIT GARCINIA MANGOSTANA L.: TEROBOSAN BARU UNTUK PERLINDUNGAN TERHADAP SIROSIS HEPATIS Rachman, Adelia Ulya; Wijaya, Marzuki Panji; Alvianita, Audesia; Hidayat, Putra Nur; Alamsjah, Jeffry
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Liver cirrhosis is caused by exposure of free radicals to the liver and can only be treated with a liver transplant. Previous studies mentioned that mangosteen (Garcinia Mangostana L.) pericarp contain antioxidant compounds. The aim of this study is to test the hepatoprotective ability of mangosteen pericarp to prevent liver cirrhosis’ progression.6 groups of mice will be given intervention and then the following parameters will be observed: serum ALT, AST, bilirubin and the histopathologic appearance of the mice’s liver. Of all four parameter that was observed, only the histopathologic appearance of the mice’s liver shows significant result.Keywords: mangosteen, cirrhosis, garcinia mangostana, herbal.
PENGEMBANGAN MARKA MOLEKULAR UNTUK KARAKTERISASI VARIETAS ANGGREK TANAH UNGGUL (SPATHOGLOTTIS) HASIL POLIPLOIDISASI DENGAN KOLKISIN Setiawan, Agus; Shochicha, Anahtadiya Nurfa; Cahya Pramana, Abrory Agus; Restiyanti, Restiyanti; Daryono, Budi Setiadi
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Characterization of Spathoglottis has not been observed yet especially in determination of genetic relationship and identification of colchisine-induced polyploid orchid. The aim of this research was to study about characterization of fingerprinting molecular mark in DNA Barcode profiling of Polyploid Anggrek Tanah (Spatholgottis sp.) and fenetic relationship of polyploid orchid with superior hybrid soil orchid (Spatholgottis sp.). The method of this research is collecting the orchid, germinating orchid seed, colchisine-induced PLB orchid, making simply buffer DNA isolation, genome DNA isolation, quantitative test of genome DNA, qualitative test of genome DNA, liquidity DNA genom, liquidity RAPD primer, PCR Random Amplified Polimorphism DNA (RAPD) of Orchid DNA, electrophoresis of PCR-RAPD, polymorphism RAPD , Dendogram RAPD analysis, dan creating Orchid DNA barcode. Based on the result known that RAPD molecular method could be used in detection of polyploid Spathoglottis sp. with OPAW11 primer. Electroforegram could be made as DNA bar-coding for Spathoglottis sp. that also could be used to to trace the origin orchids from Indonesia.Keywords: Spathoglottis, RAPD, bar-code DNA, colchisine
GANYONG (CANNA EDULIS), YANG TERABAIKAN MENJADI BENTENG KANKER USUS BESAR Ismawardika, Alifiani; Larasandi, Deasy; Sadid, Ahmad; Fiolita, Redita Elva; Prayoga Griadhi, Nyoman Odiyana
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Background : Colorectal cancer is one of the most common cancer that can lead to mortality. Since  patients come in the late stage, mostly they have bad prognosis. Thus, prevention is the most effective way to decrease the mortality and morbidity. Ganyong (Canna edulis) is plant which the root contains of high fiber and calcium which are good to prevent colorectal cancer. Aim : This experiment is conducted to examine the preventive effect of ganyong solution to the development of colorectal cancer. Method : The research design is experimental with using of post test only with control group design method. 30 male Wistar rats weighing 100-120 gram (4 week of age) are used in this experiment. The rats are devided into 6 groups randomly and each group consists of 5 rats. Group 1 got AOM/DSS only While, AOM/DSS, coconut oil and ganyong solution are given to the group 2. Then group 3 got AOM/DSS and ganyong solution and group 4 got AOM/DSS and coconut oil. Group 5 got coconut oil and ganyong solution. And group 6 which is negative control group got aquadestIndependent t test is used to analyse the data. Result: Macroscopically, the amount of rats that have nodule in G2 (75%) is lesser than G4 (100%). Microscopically, there are 3 rats from G1 having adenokarsinoma while only 2 rats from G3 having same thing. Statistically this difference is significant (p>0,05). Conclusion : Ganyong can decrease the number of nodule in group which was given coconut oil. And  microscopically it can effective in preventing the tumor development in group without coconut oil.   Keyword : Canna edulis, colorectal cancer , prevention
TEKNOLOGI PEMANEN KABUT (FOG HARVESTING) SEBAGAI SOLUSI MENGATASI MASALAH KEKERINGAN PADA DATARAN TINGGI Taufani, Aditya Riski; Utomo, Puji; Maulana, Taufiq Ilham; Musofa, Musofa
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Drought occur in Ngoho Plateu, Semarang and always happened in dry season. However, the plateu has a big potential of fog, which always occur in wet and dry season. This research purposes to determine the potential of fog  harvesting, 4 models of standard fog collectors (SFC) were installed in two locations. Each location were installed 2 models with azimuth of 90o and 180o. Data collected for 4 months, on condition where foggy day only. Equipment that harvested largest amount of fog water was model 4 which were mounted on highest land of plateu azimuth of 90o. Model 4 was capable to harvest water 8 liter/m2 in fog duration of 8 hours. Keywords : water, fog, standard fog collector
SINTESIS POLIANILIN YANG DIPERKAYA γ-Fe2O3 DARI PASIR BESI LOKAL SULAWESI TENGGARA UNTUK APLIKASI Anton, Ardin; Nalis, M.; Taswito, C. C. N.; Agusu, La
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

This research is aimed to develop the radar absorbing material based on polyaniline enriched by γ-Fe2O3 synthetized from the sandstone. γ-Fe2O3 is, then, derived from calcination process of Fe3O4 powder at the temperature of 400-600oC. Fe3O4 powder itself is extracted from the local sandstone of South East Sulawesi area by using the co-precitipation method with both HCl and NH4OH act as the solvent and precitipation agent, respectively. The polyaniline is synthetized from its monomer, aniline, where both HCl and NH4OH are also used as a dopant and an oxydator agent, respectively. Effect of reaction pH on the crystal size of Fe3O4 is also investigated. The XRD spectrum shows that a rather high purity of Fe3O4 in nano size is being achieved at the pH value of 8 and 9. However, at a rather low pH value (6.5 and 7.5), the additional weak peaks in XRD spectrum shows the existence other metal compounds impurity. The crystal sizes is approximately ~8.01 and 11.07 nm for pH value of 8 and 9. The VSM measurement result shows that the saturated magnetization value of Fe3O4 is 24.45 emu/g. The Fe3O4 is calcined at temperature of 500oC for 3 hours to get γ-Fe2O3. Finally, the polyaniline-γ-Fe2O3 composites were synthetized using an insitu polymerization method where the weight contents of γ-Fe2O3 are 5, 10, 15, and 20 percent. Those materials will be useful as a prospective application in radar absorbing materials technology at frequency ranges of 9-17 GHz.           Keywords: polyaniline, γ-Fe2O3, co-precitipation, sandstone, radar absorbing materials
EKSTRAK CACING TANAH SEBAGAI INOVASI PENYEMBUHAN ULKUS DIABETIK BERBASIS INDUKSI DENSITAS AKSON Mardiati, Ni Putu Jeny; Yunitasari, Arinda Nur; Sari, Dwi Astika; Saraswasta, I Wayan Gede; Putra, Fetreo Negeo; Kristianto, Heri
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Reduction of nerve growth factor expression in diabetic ulcer affects overall wound healing. Earthworm (Pheretima aspergillum) can stimulate schwann cell proliferation and migration to support axonal elongation. The objective of this study is to compare wound healing functions in diabetic ulcer of rats using earthworm extract, hydrogel, and conventional dressing. This study applied a true-experimental posttest only controlled group design. 21 days after treatment, the group receiving earthworm extract had a significantly higher percentage of wound contraction and axonal density compared to the control group (p<0.05). These results show that earthworm extract can promote wound healing in diabetic ulcer. Keywords: Diabetic Ulcer, Earthworm (Pheretima aspergillum), Wound Contraction, Peripheral Nerve Regeneration.

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