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INDONESIA
Indonesian Journal of Pharmaceutical Science and Technology
Published by Universitas Padjadjaran
ISSN : 23561971     EISSN : 2406856X     DOI : -
Core Subject : Health, Science,
Computer Science & IT Medicine & Pharmacology
Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan pendekatan yang lebih kolaboratif dalam Sains dan Teknologi Farmasi.
Arjuna Subject : -
Articles 14 Documents
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Search results for , issue "Suppl. 5, No. 1 (2023)" : 14 Documents clear
Analysis of Vitamin C and Antioxidant Activity of Capsicum frutescens L. and Capsicum annuum L. St Maryam; Rais Razak; Muzakkir Baits; Ainun Fadhilah Salim
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.46082

Abstract

Vitamin C is a nutrient that the body needs in order to increase its metabolism. This helps the body to create collagen and also act as an antioxidant. This study aims to analyze of vitamin C and the antioxidant activity of Capsicum frutescens L. and Capsicum annuum L. (curly and large chili variety), obtained from the Pinrang Regency, South Sulawesi Province. The study was carried out experimentally using the UV-Vis spectrophotometry method. The measurement of vitamin C was carried out at a wavelength of 265.667 nm while for the antioxidant activity test the maximum wavelength of DPPH was 515.961 nm. Vitamin C levels obtained in Capsicum frutescens L. and Capsicum annuum L. (curly and large chili variety), were 0.926; 0.344 and 0.281 % w/w. For antioxidant activity, the results of Capsicum frutescens L. and Capsicum annuum L. (curly and large chili variety), were 2.202; 2,260; and 2.751 ppm while the comparator vitamin C was 12.360 ppm. These results indicate that Capsicum frutescens L. has higher levels of vitamin C than Capsicum annuum L. (curly and large chili variety), while for the antioxidant activity test, the IC50 value of Capsicum frutescens L. and Capsicum annuum L. (curly and large chili variety) had less antioxidant activity than a comparison vitamin C, which means that they have strong antioxidant activity.
Studi In Silico dan In Vitro Senyawa Aktif pada Rimpang Kunyit (Curcuma domestica) sebagai Antiinflamasi pada Cyclooxygenase-2 (COX-2) Devani Olivia Winardi; Syahla Afaaf Alliyah; Shafa Nurul Fadilah; Jessyca Sirait; Hafidh Beta Arif Putra; Nurhanifah Puspitadewi; Neli Neli; Muchtaridi Muchtaridi; Ade Zuhrotun
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.47171

Abstract

Dismenore merupakan kondisi nyeri yang umum pada wanita pada saat sedang menstruasi. Pengobatan untuk dismenore umumnya menggunakan obat berupa obat antiinflamasi non steroid (NSAID).  Efek antiinflamasi ini juga dapat diperoleh dari bahan alami, seperti rimpang kunyit. Rimpang kunyit mengandung senyawa kurkuminoid yang telah dikonfirmasi dari berbagai studi memiliki berbagai khasiat bagi tubuh, diantaranya adalah sebagai antivirus, antibakteri, antioksidan, antikarsinogenik, dan antiinflamasi. Penelitian ini dilakukan untuk menguji keefektifan dan potensi sifat antiinflamasi pada senyawa-senyawa yang terkandung dalam kunyit yang dilakukan berdasarkan studi in silico dan in vitro dengan prediksi sifat fisikokimia dan sifat farmakokinetik berdasarkan sifat Lipinski dan ADME-T, penambatan molekul, pemodelan farmakofor, dan pengujian toksisitas menggunakan metode BSLT. Hasil yang diperoleh adalah senyawa-senyawa uji memenuhi Lipinski rules of five, beberapa senyawa hasil uji bersifat mutagen dan karsinogen. Senyawa dengan potensi antiinflamasi tinggi adalah dihidrokurkumin. Dari hasil BSLT, ditemukan bahwa ekstrak infus kunyit memiliki sifat toksik.
ANTIOXIDANT ACTIVITY OF EXTRACT COMBINATION FROM Averrhoa bilimbi L. LEAVES AND STINGLESS BEE HONEY Bunga Putri Sari; Paula Mariana Kustiawan
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.45987

Abstract

Belimbing wuluh (Averrhoa bilimbi L.) leaves and stingless bee honey contains phenolic compounds that can act as antioxidants. This study aims to find out the antioxidant activity of extract combination from stingless bee honey (Trigona spp.) and Belimbing Wuluh (Averrhoa bilimbi L.) leaves. This research was used DPPH (2,2-diphenyl-1-picrilhidrazyl) method. Then measured by UV-VIS spectrophotometry. The results showed the greatest IC50 of extract combination from stingless bee honey and Averrhoa bilimbi L. leaves was 2:1  (90,36 ppm) and was classified as strong activity. This activity was influenced by the synergistic effect between the combination of secondary metabolites contained therein.
Quality of Pharmaceutical Services on Patient Loyalty of RSUD Soewandhie Surabaya Ira Purbosari; Intan Ayu Kusuma Pramushinta; Asri Wido Mukti; Dian Viciennsia Sigalingging
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.46083

Abstract

Quality of health services is an important thing. The level of perfection of a service to increase patient satisfaction. The quality of patient care is very influential on loyalty. The purpose of this study was to assess the quality of medical services at pharmaceutical facilities and patient retention at RSUD Dr. Mohamad Soewandhie and saw the relationship between the quality of health services and the loyalty of BPJS and non-BPJS patients. This research is a descriptive research with a survey method using a questionnaire to 150 respondents who meet the research inclusion criteria. The research instrument used was a closed questionnaire with a total of 19 questions. Furthermore, the data obtained were analyzed descriptively, and then the Chi-square test was carried out to determine the relationship between research variables. The results of this study are included in the good category for service quality, with the percentage of respondents who answered at 53.3% and loyalty at 65.3%. There is a significant relationship between the quality of pharmacy installation services and patient loyalty

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