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INDONESIA
Indonesian Journal of Pharmaceutical Science and Technology
ISSN : 23561971     EISSN : 2406856X     DOI : -
Core Subject : Health, Science,
Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan pendekatan yang lebih kolaboratif dalam Sains dan Teknologi Farmasi.
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Articles 6 Documents
Search results for , issue "Vol 2, No 1 (2015)" : 6 Documents clear
Formulasi dan Uji Stabilitas Tetes Mata Sulfasetamida Abdassah, Marline; Noviardani, Tenri; Levita, Jutti; Suherman, Shelvy E
Indonesian Journal of Pharmaceutical Science and Technology Vol 2, No 1 (2015)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (140.024 KB) | DOI: 10.15416/ijpst.v2i1.7808

Abstract

 Tetes mata sulfasetamidayang mengandung natrium sulfasetamida 10%, 15%, dan 30% telah dibuat dan disterilkan. Metode sterilisasi yang digunakan adalah uap air mengalir 98-100 oC, penyaring bakteri, dan autoklaf 120-121 oC selama 15 menit. Tujuan penelitian ini adalah mendapatkan sediaan yang paling stabil selama penyimpanan 28 hari. Semua sediaan diamati kejernihan, pH dan konsentrasi natrium sulfasetamida.Semua sediaan mengalami kenaikan pH. Kekeruhan terjadi pada sediaan yang disterilkan dengan autoklaf. Sediaan paling stabil adalah tetes mata yang mengandung natrium sulfasetamid 10% yang disterilisasi dengan penyaring bakteri.
Effect of Adding Granul Basil (Ocimum americanum) as Antioxidants in Fried Foods Deden I Dinata; Dadih Supriadi; Garnadi Djafar; Syerliana Syerliana; Wahyu Wijayanti; Shelvy E Suherman
Indonesian Journal of Pharmaceutical Science and Technology Vol 2, No 1 (2015)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (471.482 KB) | DOI: 10.15416/ijpst.v2i1.7807

Abstract

Basil is one of medicinal plants in Indonesia that has been used empirically as antimicrobes, analgetic, antiinflammatory, antivirus, antitumor, and antioxidants that prevented ischemia. This research aimed to investigate the effect of adding granule ethanol extract of basil leaves (Ocimum americanum) as antioxidant to capture free radicals in fried foods. The antioxidant activity of ethanol extract of basil leaves with DPPH determinated by IC50, comparing the antioxidant activity of the granule and the control by determination of quality properties of oil and food after frying using Fourier Transfor Infra Red (FTIR) spectra, and quantitative parameters by determination percentage of free fatty acid (FFA). Results of maceration with ethanol 15.94% w/w, total ash content 9.85%, water soluble ash content 3.98%, acid insoluble ash content 3.98%, water soluble extract 25.89%, ethanol soluble extract 12.76%, water content 6.87%, drying shrinkage 11.19%. Testing the antioxidant activity of the ethanol extract of basil leaves with DPPH gave IC50 of 80.55 ppm. The result of antioxidant testing by determination percentage of FFA statistically with ANOVA (significance 0.00<5) and comparison of the concentration extract in basil granule with LSD test significantly different. The result indicates that adding ethanol extract of granules basil on fried foods gave antioxidant activity because it can inhibit the increasing of FFA percentage. Keywords: Antioxidant, basil leaves, DPPH, granule
Formulasi dan Uji Stabilitas Tetes Mata Sulfasetamida Marline Abdassah; Tenri Noviardani; Jutti Levita; Shelvy E Suherman
Indonesian Journal of Pharmaceutical Science and Technology Vol 2, No 1 (2015)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (140.024 KB) | DOI: 10.15416/ijpst.v2i1.7808

Abstract

 Tetes mata sulfasetamidayang mengandung natrium sulfasetamida 10%, 15%, dan 30% telah dibuat dan disterilkan. Metode sterilisasi yang digunakan adalah uap air mengalir 98-100 oC, penyaring bakteri, dan autoklaf 120-121 oC selama 15 menit. Tujuan penelitian ini adalah mendapatkan sediaan yang paling stabil selama penyimpanan 28 hari. Semua sediaan diamati kejernihan, pH dan konsentrasi natrium sulfasetamida.Semua sediaan mengalami kenaikan pH. Kekeruhan terjadi pada sediaan yang disterilkan dengan autoklaf. Sediaan paling stabil adalah tetes mata yang mengandung natrium sulfasetamid 10% yang disterilisasi dengan penyaring bakteri.
Interaction of Andrographolide with Neuraminidase of H5N1 Virus and Nuclear Factor-kappaB Jutti Levita; Monika Novryanti; Masripah Masripah; Driyanti Rahayu; Shelvy E Suherman
Indonesian Journal of Pharmaceutical Science and Technology Vol 2, No 1 (2015)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.767 KB) | DOI: 10.15416/ijpst.v2i1.7804

Abstract

Diuretic Activity and Acute Toxicity of Combination Eurycoma longifolia Extract and Irbesartan Nurmeilis Nurmeilis; Dyah A Woro; Atiek Soemiati; Anis Khoirunisa
Indonesian Journal of Pharmaceutical Science and Technology Vol 2, No 1 (2015)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (340.213 KB) | DOI: 10.15416/ijpst.v2i1.7805

Abstract

Effectiveness of Internal Chemical Indicator Strips for Class IV and V Insan S.K. Syah; Sohadi Warya; Vidhya Rohinee A/P Murugan@ Gopal; Anis Khoirunisa
Indonesian Journal of Pharmaceutical Science and Technology Vol 2, No 1 (2015)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.141 KB) | DOI: 10.15416/ijpst.v2i1.7806

Abstract

Infections through contaminated medical equipments are a serious threat to any patient’s safety and could be dangerous this treatment or may lead to new illness. Sterilization process was a compulsory procedure to ensure sterility of medical equipments where chemical indicators were broadly used to monitor sterilization process. The purpose of this study is to determine the development of internal chemical indicators strips of class IV and V in the steam sterilization in order to obtain good and quality products. Internal chemical indicator strips were able to provide visual verification on products that had passed through the sterilization process, with colour change on the indicator. The stages in this research had also included microbial contamination test Laminar Air Flow (LAF), dosage formulations Sodium Chloride (NaCl) 0.9% infusion, application of internal chemical indicator strips in the moist heat sterilization process and evaluation of NaCl 0.9% infusion that includes sterility test. This study was carried comprising 7 variations of time with data that showed a positive reaction for both indicators with a change of colour after 121 °C of sterilization. Sterility test showed no microbial growth starting from the sterilization time of 10.5 minutes. This research had successfully concluded that internal chemical indicator strips class IV and V were effective on steam sterilization at 121 °C for 10.5 minutes and could be used to monitor the sterilization process. Keywords:Internal chemical indicators strips of class IV and V, NaCl 0.9% infusion, steam sterilization

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