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INDONESIA
Jurnal Farmasi Klinik Indonesia
Published by Universitas Padjadjaran
ISSN : 23375701     EISSN : 2337 5701     DOI : -
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Indonesian Journal of Clinical Pharmacy (IJCP) is a scientific publication on all aspect of clinical pharmacy. It published 4 times a year by Clinical Pharmacy Master Program Universitas Padjadjaran to provide a forum for clinicians, pharmacists, and other healthcare professionals to share best practice, encouraging networking and a more collaborative approach in patient care. Indonesian Journal of Clinical Pharmacy is intended to feature quality research articles in clinical pharmacy to become scientific guide in fields related to clinical pharmacy. It is a peer-reviewed journal and publishes original research articles, review articles, case reports, commentaries, and brief research communications on all aspects of Clinical Pharmacy. It is also a media for publicizing meetings and news relating to advances in Clinical Pharmacy in the regions.
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Search results for , issue " Vol 2, No 4 (2013)" : 5 Documents clear
Peresepan Obat Pasien Penyakit Dalam Menggunakan Indikator Peresepan World Health Organization Destiani, Dika P.; Susilawati, Susilawati
Indonesian Journal of Clinical Pharmacy Vol 2, No 4 (2013)
Publisher : Indonesian Journal of Clinical Pharmacy

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Abstract

Ilmu penyakit dalam merupakan cabang ilmu kedokteran yang harus memberikan pelayanan komprehensif dengan pendekatan yang bersifat holistik. Pendekatan holistik dalam menegakkan diagnosis dengan melihat gejala-gejala yang timbul sehingga memungkinkan peresepan obat yang banyak dan memungkinkan terjadinya polifarmasi. Penelitian ini bertujuan untuk memantau penggunaan obat spesialis penyakit dalam dengan menggunakan lima indikator peresepan berdasarkan guideline WHO yaitu jumlah obat per lembar resep, penggunaan obat generik, antibiotik, sediaan parenteral, dan obat esensial. Pengumpulan data resep rawat jalan spesialis penyakit dalam diambil secara retrospektif pada periode Januari–Maret 2013 di salah satu fasilitas pelayanan kesehatan di Bandung. Dari 186 lembar resep dengan 567 permintaan obat didalamnya diperoleh rata-rata jumlah obat per lembar yaitu3,05 permintaan obat per lembar. Penggunaan obat generik sebesar 23,63% dari 567 obat. Persentase penggunaan antibiotik dan sediaan parenteral sebesar 17,20% dan 4,84% dari 186 lembar resep, sedangkan penggunaan obat esensial sebesar 36,86% dari 567 obat yang diresepkan. Hasil studi menyatakan tidak terjadi polifarmasi pada fasilitas kesehatan tempat studi berlangsung. Penggunaan obat generik dan esensial masih rendah. Selain itu diketahui tidak ada penyimpangan (misuse) penggunaan antibiotik dan sediaan injeksi, sehingga mengurangi kejadian resistensi antimikroba di masyarakat.Kata kunci: Penyakit dalam, indikator peresepan, polifarmasi, resistensiAssesment of Drug Use in Internal Medicine Patients using World Health Organization IndicatorsInternal medicine is the branch of medicine that should provide comprehensive knowledge of disease with a holistic approach. Holistical approach done by developing symptoms and signs for diagnostic and it would be polypharmacy. This study aimed to evaluate drug use by the internal medicine using five prescribing indicators WHO guideline such as average number of drugs per encounter, percentage of drugs prescribed by generic name, percentage of encounters with an antibiotics and injection prescribed, and drugs prescribed from essential drugs list or formulary. Outpatient prescription of internal medicine period Januari to Maret 2013 in one of health facilities in Bandung collected retrospectively. Average number of drugs per encounter was gained by dividing 567 drugs with 186 prescription. Percentage of using generic drugs was 23,63%, antibiotics and injection drugs were 17,20% and 4,84% per encounters, whereas percentage of drugs prescribed from essential drugs list was 36,86%. The result showed that the usage of generic drugs and essential drugs are low and should be improved. Furthermore, there are no misuses usage of antibiotics and injection, thereby can minimize antimicrobial resistances.Key words: Internal medicine, prescribing indicator, polypharmacy, resistances
Pengaruh Pelayanan Informasi Obat terhadap Keberhasilan Terapi Pasien Diabetes Melitus Tipe 2 Insani, Widya N.; Lestari, Keri; Abdulah, Rizky; Ghassani, Salma K.
Indonesian Journal of Clinical Pharmacy Vol 2, No 4 (2013)
Publisher : Indonesian Journal of Clinical Pharmacy

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Abstract

pemahaman mengenai instruksi pengobatan merupakan permasalahan utama dalam pengobatan DMT2. Ketidakpatuhan pasien terhadap regimen obat hipoglikemik oral yang kompleks serta ketidaktepatan dalam cara dan waktu pengonsumsiannya merupakan barrier tercapainya keberhasilan terapi DMT2. Hal ini sangat berkaitan dengan kualitas pelayanan kefarmasian yang diberikan kepada pasien, khususnya pelayanan informasi obat. Penelitian ini bertujuan untuk mengevaluasi pengaruh intervensi pelayanan informasi obat terhadap parameter keberhasilan terapi diabetes yaitu glukosa 2 jam postprandial, HDL dan trigliserida. Penelitian ini merupakan nonrandomized concurrent control trial secara prospektif. 14 subjek uji direkrut selama 4 bulan selama Mei–Agustus 2013 kemudian dibagi menjadi dua grup. Kedua grup mendapat terapi pengobatan diabetes berupa hipoglikemik oral. Grup intervensi mendapatkan pelayanan informasi obat dan edukasi mengenai diabetes, sedangkan grup kontrol tidak mendapatkannya. Data dianalisis menggunakan uji t independen dengan α 0,05. Walau belum berbeda signifikan, nilai keberhasilan terapi dengan intervensi pelayanan informasi obat pada parameter glukosa 2 jam postprandial, HDL dan trigliserida memberikan hasil yang lebih tinggi 17,01%; 6,73%; dan 6,31% untuk masing-masing parameter dibandingkan terapi tanpa pelayanan kefarmasian tersebut.Kata kunci: Pelayanan informasi obat, diabetes, obat hipoglikemik oral Effect of Pharmaceutical Information Care on Clinical Outcomes of Patients With Type 2 Diabetes MellitusPoor adherence to medication and lack of understanding about medication instructions are the main problems in the treatment of type 2 diabetes mellitus. Poor adherence to oral hypoglicemic drugs which have complex regiment and unappropriate consumption of them are the obstacles to reach good clinical outcomes. These problems are highly related to the quality of pharmaceutical care given to patients. The aim of this study was to evaluate the effect of pharmaceutical information care towards the outcome of type 2 diabetes mellitus including 2 hours postprandial glucose, HDL and tryglicerides. This study used nonrandomized concurrent control trial prospectively. 14 subjects were recruited during 4 months from May–August 2013 and were divided into two groups. Both of group were given oral hypoglycemic drugs. The intervention group received pharmaceutical information care and diabetes education, whilecontrol group did not receive these. Data were then analysed with independent t test using α 0,005. Although the difference were not significant yet, pharmaceutical information care intervention on diabetes treatment gave higher improvement by 17,01%; 6,73%; and 6,31% respectively in 2 hours postprandial glucose, HDL and tryglicerides parameters, compared with the treatment without pharmaceutical care.Key words: Pharmaceutical information care, diabetes, oral hypoglicemic drugs
Efektivitas Edukasi Terapi Insulin terhadap Pengetahuan dan Perbaikan Glikemik Pasien Diabetes Melitus Pramita, Zenia; Aditama, Lisa
Indonesian Journal of Clinical Pharmacy Vol 2, No 4 (2013)
Publisher : Indonesian Journal of Clinical Pharmacy

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Abstract

Diabetes Self Management Education (DSME) merupakan salah satu strategi penting dalam penatalaksanaan Diabetes Melitus (DM). Manajemen terapi insulin merupakan peran penting dari tenaga kesehatan untuk meningkatkan pengetahuan dan tercapainya kontrol glikemik yang lebih baik. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian edukasi manajemen terapi insulin tehadap peningkatan pengetahuan dan perbaikan kontrol glikemik (penurunan HbA1c) pada pasien DM tipe 2 yang menggunakan insulin. Penelitian menggunakan desain RCT (randomized control trial) dengan pengambilan sampel secara systematic random sampling. Subjek penelitian dibagi dalam kelompok kontrol yang tidak mendapat intervensi dan kelompok uji yang mendapat intervensi edukasi manajemen terapi insulin oleh farmasis selama 1 bulan. Data yang diperoleh dianalisis menggunakan statistik uji t-test. Hasil uji paired t-test pada masing-masing kelompok uji dan kontrol menunjukkan bahwa ada perbedaan yang bermakna antara pengetahuan sebelum dan sesudah edukasi (p=0,001 dan p=0,011) dan tidak ada perbedaan antara HbA1c sebelum dan sesudah edukasi (p=0.274 dan p=0,166). Hasil uji independent t-test menunjukkan bahwa edukasi manajemen terapi insulin efektif terhadap peningkatan pengetahuan (p=0,034), tetapi tidak efektif terhadap perbaikan kontrol glikemik (p=0,463).Kata kunci: Manajemen terapi insulin, edukasi, farmasi komunitas, pengetahuan, kontrol glikemikEffectiveness of Insulin Therapy Education on The Improvement of Knowledge And Glycemic Control In Type 2 Diabetes Mellitus Patients Diabetes Self Management Education (DSME) is one of the important strategies of diabetes management. Insulin therapy management is the important role of healthcare professional to enhance patient’s knowledge and self management for better glycemic control. This study aimed to determine the effect of insulin therapy management education on increased knowledge and improved glycemic control (HbA1c reduction) in patients with type 2 diabetes who use insulin. The design of this study is RCT (randomized controlled trials) with systematic random sampling. Study participants were divided into a control group that received no intervention and the test group that received the intervention about insulin therapy management education by pharmacist for 1 month. Data were analyzed using t-test groups. The results showed that the paired t-test on each trial and control groups showed that there were significant differences between knowledge before and after education (p=0.001 and p=0.011) and there was no difference between HbA1c before and after education (p=0.274 and p=0.166). Results of independent t-test showed that insulin therapy management education significantly effective to increased knowledge (p value=0.034), but did not have a significant effect to improved glycemic control (p value=0.463)Key words: Insulin therapy management, education, community pharmacy, knowledge, glycemiccontrol
Swamedikasi di Kalangan Masyarakat Perkotaan di Kota Yogyakarta Widayati, Aris
Indonesian Journal of Clinical Pharmacy Vol 2, No 4 (2013)
Publisher : Indonesian Journal of Clinical Pharmacy

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Abstract

Penelitian observasional potong lintang ini bertujuan mengeksplorasi prevalensi dan pola swamedikasi di Kota Yogyakarta. Sejumlah 640 sampel di Kota Yogyakarta dipilih secara klaster acak pada periode Maret–Mei 2010. Data yang diperoleh kemudian dianalisis secara statistik deskriptif. Sebanyak 50% dari responden tersebut berswamedikasi satu kali, 33% dua kali dan 17% lebih dari dua kali. Responden yang membeli obat modern sebanyak 86% dan obat tradisional sebanyak 14%. Obat swamedikasi diperoleh dari apotek (42%), toko/warung kelontong (35%), toko obat (7%), dan kombinasi ketiganya (16%). Sebanyak 99% responden sembuh atau setidaknya berkurang keluhannya setelah berswamedikasi. Jika tidak sembuh setelah berswamedikasi, 45% responden menyatakan akan pergi ke dokter, sementara 20% lainnya ke puskesmas, 5% ke rumah sakit dan 5% kembali melakukan swamedikasi. Sumber informasi tentang obat mereka peroleh dari iklan (32%), dokter (17%), teman (17%), dan dari apotek (5%). Alasan mereka berswamedikasi antara lain pengalaman sembuh menggunakan obat tersebut sebelumnya (24%), berpersepsi bahwa penyakitnya ringan (22%), cepat dan praktis (17%) dan murah (13%). Temuan diatas mengindikasikan peluang dari aspek bisnis apotek sekaligus tantangan peningkatan peran profesi apoteker terutama di apotek dalam membantu masyarakat berswamedikasi secara tepat.Kata kunci: Swamedikasi, masyarakat perkotaanSelf-Medication among Urban Population in YogyakartaThis observational cross-sectional study is aimed at exploring prevalence and patterns of SM in Yogyakarta. A cluster random sampling technique was applied to select 640 adults in Yogyakarta between March and May 2010. From a total of 559 completed questionnaires, 247 (44%) respondents who had self-medicated during two previous weeks were included in subsequent analysis. Among these respondents, 50%had self-me-dicated once, 33% twice and 17% more than two times. Eighty-six percent of respondents had consumedmodern medicines while the rest 14% had used traditional ones. The drug for SM was obtained from pharmacies (42%), groceries (35%), drug stores (7%) and combination of those three sources (16%). Most of the respondents (99%) were recovered from their illnesses or at least experienced a symptom relieve after SMs. Forty-five percent respondents stated that they will visit a physician when they see no improvement after SM, while the rest said they will visit primary healthcenters (20%) and hospitals (5%) orrepeat their SM (5%). Information about the medicines areobtained from advertisements (32%), physicians (17%), friends (17%) and pharmacists (5%). The motivation for SM are previous experience of being relieved (24%), perception that they haveminor illnesses (22%), quick and easy (17%) and cheap (13%). Above findings indicate a business opportunityof pharmacies and a challenge to improve the role of pharmacists in assisting people regarding the selection of medicines for SM.Key words: Self-medication, urban people
Analisis Interaksi Obat Pasien Rawat Inap Anak di Rumah Sakit di Palu Sjahadat, Akhmed G.; Muthmainah, Siti S.
Indonesian Journal of Clinical Pharmacy Vol 2, No 4 (2013)
Publisher : Indonesian Journal of Clinical Pharmacy

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Abstract

Penelitian interaksi obat telah dilakukan pada pasien rawat inap anak di salah satu rumah sakit di Kota Palu. Pengetahuan mengenai interaksi obat penting untuk mencegah morbiditas dan mortalitas serta meningkatkan keamanan pasien. Rancangan penelitian yang digunakan adalah studi cross sectional deskriptif dengan pengambilan data secara retrospektif mulai bulan Januari sampai Desember 2012. Kriteria inklusi yang digunakan yaitu populasi pasien anak usia 0 sampai 18 tahun yang dirawat di rumah sakit tahun 2012 dan memperoleh 2 atau lebih jenis obat dalam satu lembar resep, sedangkan kriteria eksklusinya yaitu pasien anak dalam perawatan gawat darurat, ICU, dan mendapatkan resep obat-obat topikal seperti salep, krim, tetes mata, tetes telinga dan tetes hidung. Setiap jenis obat dalam lembar resep dianalisis dengan menggunakan bank data dari software Drug.Com. Data diambil dari 495 pasiendengan jumlah resep keseluruhan sebanyak 3650 resep. Berdasarkan jumlah tersebut dapat diidentifikasi 230 interaksi (6,30%), terdiri dari 6,53% mayor, 48,69% moderat, 44,78% minor. Berdasarkan hasil penelitian dapat disimpulkan bahwa hasil interaksi obat yang sering terjadi antara lain kombinasi rifampicin dengan isoniazid, ibuprofen dengan deksametason, asetaminofen dengan isoniazid, gentamicin dengan sefotaksim, gentamicin dengan seftriakson dan diazepam dengan deksametason.Kata kunci: Pasien anak, rawat inap, interaksi obatAnalysis of Drugs Interaction among Pediatric Inpatients at Hospital in PaluWe performed drug interaction analyses in the pediatric inpatient unit at one of hospitals in Palu. In this study, those analysesstudy are important to prevent childhood morbidity, mortality and to improve patient’s safety. By using a cross-sectional descriptive study, we collected retrospective data from January until December 2012. We included patients at age of 0- 18 years old who were hospitalized during 2012 and received two or more drugs from a prescription sheet. In particular, we excluded pediatric inpatients in emergency and intensive care units who received topical medications (e.g., ointment, creams, eye drops, ear drops, and nasal drops). Each drug was analyzed by using Drug.Com software. In total, we collected data from 495 patients in 3650 prescription sheets. Based on those data, we identified 230 interactions (6.30%) which could be classified into three levels: major (6.35%), moderate (48.68%) and minor interactions (44.78%). We found several drug interactions in the combination of rifampicinisoniazid, dexamethasone-ibuprofen, acetaminophen-isoniazid, gentamicin-cefotaxime-ceftriaxone and diazepam-dexamethasone.Key words: pediatric patients, hospitalization, drug interactions

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