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Biology, Medicine, & Natural Product Chemistry
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Core Subject : Health, Science,
BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for researchers in these fields, and with the aim to set international standards in their methodology.
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Articles 4 Documents
Search results for , issue "Vol 3, No 2 (2014)" : 4 Documents clear
Larvicidal Activity of A Mixture of Cashew Nut Shell Liquid and Water-Soluble Extract of Soap Nut Fruit (Sapindus rarak DC.) Against 3rd Instar Larvae of Aedes aegypti Glory Resia Raraswati; Sudarsono Sudarsono; Budi Mulyaningsih
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (558.765 KB) | DOI: 10.14421/biomedich.2014.32.53-57

Abstract

Cashew Nut Shell Liquid (CNSL) which has been known as a waste of processing cashew fruits which is contain phenolic compounds have activity as larvicides. Cashew nut shell liquid is not soluble in the water where the larvae grow. Cashew nut shell liquid mixed with water-soluble extract of soapnut fruit which serves as a natural surfactant that can emulsify oil in water. The test subjects were larvae of Aedes aegypti third instar. Test subjects were divided into treatment group and control group. In the treatment group, test subjects were  the mixture of CNSL and Ethylacetat Soluble Extract (ESE) in tap water. The Larvae mortality observations were done 24 hours after the treatment. LC50 and LC90 as final test data were analyzed using probit analysis. Extract constituents   of CNSL and Water Soluble Extract of SoapNut fruit (WSEoSN) were  investigated using Thin Layer Chromatography (TLC) method. The effect of CNSL as larvicides against third instar larvae of Ae. aegypti with were LC50 of 14,12 ppm, while the LC90 of 24,85 ppm.
The Antidepressant Effects of (Arcangelisia flava (l.) Merr) Water-Soluble Extract in Balb-C Mice Reviewed from Immobility Time by Forced A, Tiara; H, Arief R; Sudarsono, Sudarsono
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.776 KB) | DOI: 10.14421/biomedich.2014.32.65-67

Abstract

This study was conducted to examine / determine the antidepressant effects of (Arcangelisiaflava L.) on immobility time of the white male mice strain Balb-c by the forced swim test method. The method of research using laboratory animals such as 25 micewas divided into 5 groups. As a negative control group was only given distilled water ad libitum. Amitryptiline was used as the positive control group; the experiment group was a water-soluble extract of A.flava by  multiple doses. The results showed that the best antidepressant effects were312 mg/kgBW ; it had a minimum of immobility time compared with the other groups.
A Discovery and Characteristics Description of Telosma puberula (Asclepiadoideae) in Mount Gedang Atas and Mount Ijo, Baturagung Mountain Yogyakarta Widodo Widodo
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1356.359 KB) | DOI: 10.14421/biomedich.2014.32.47-52

Abstract

Population of Telosma puberula in community forest bushes was identified at S.07.48'.44.1"; E.110.31.15.8", 411m, Mount Gedang Atas and S 070  04 '04.1"; E 1100  30 '47.9 ", 415m, Mount Ijo. Telosma puberula was also found in Mount Parangan, Mount Mintorogo, Mount Nglanggeran, and Baturagung Mountains Yogyakarta. The identification was based on herbarium specimens collected by Horsfield in 1802 and 1859 from Java island, Indonesia (K000873052, K000873053). Information about Telosma puberula is very limited. This article describe photographs of morphological characters of the plant’s stems, leaves, flowers, and pollinia.
Substitution and Haplotype Diversity Analysis on The Partial Sequence of The Mitochondrial DNA Cyt b of Indonesian Swamp Buffalo (Bubalus bubalis) Akhmad Sukri; Mohamad Amin; Aris Winaya; Abdul Gofur
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1514.606 KB) | DOI: 10.14421/biomedich.2014.32.59-63

Abstract

This research aims to investigate the substitution pattern of nucleotide base and haplotype diversity of Indonesian swamp buffalo (Bubalus bubalis) based on the mitochondrial DNA cyt b partial gene sequence. 17 samples were chosen from 7 different regions with each uniquely represents Indonesian biogeography which comprise Aceh, Riau, Madiun, Blitar, Lombok, South Borneo and Tana Toraja. The result of cyt b gene sequence alignment showed the presence of transition and transversion substitutions and the absence of insertion and deletion. The amount of transitions was found to be higher than that of transversions and the amount of substitution in pyrimidine was also higher than that in purine. The highest amount of transitions happened in base TàC which is a silent substitution. The result of median joining network analysis showed that Indonesian haplotype Bubalus bubalis could be classified into 16 haplotypes which form different haplogroups unique to their geographical region. The result of median joining network analysis also indicated that the genetic relationships of swamp buffaloes (Bubalus bubalis) in Indonesia are highly influenced by their geographical locations.

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