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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 13 Documents
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Search results for , issue "Vol 15, No 2 (2015)" : 13 Documents clear
Hubungan Kadar Ekskresi Yodium Urin Ibu Menyusui dengan Perkembangan Bayi Usia Bawah 2 Tahun di Daerah Endemik GAKY Saputra, Rizky Hermawan; Noor, Zulkhah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2015): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v15i2.3759

Abstract

Gangguan akibat kekurangan yodium (GAKY) pada bayi berdampak menghambat proses tumbuh kembang. Penelitian ini bertujuan untuk mengetahui hubungan kadar ekskresi yodium urin (EYU) ibu menyusui dengan perkembangan bayi usia dibawah dua tahun di daerah endemik GAKY. Penelitian ini bersifat observational dengan desain cross sectional. Sampel penelitian adalah 30 ibu menyusui yang memiliki bayi berusia dibawah dua tahun. Kadar EYU diukur dengan menggunakan Ammonium Persulfat Dry Digestion dan Perkembangan bayi dinilai dengan menggunakan Kuesioner Pra Skrining Perkembangan (KPSP). Kadar median EYU ibu kemudian dikorelasikan dengan status perkembangan bayi, menggunakan uji Spearman. Hasil menunjukkan bahwa kadar EYU ibu optimal (173,5 ppm). Sebanyak sembilan ibu (30%) memiliki status EYU optimal, namun status perkembangan bayi dengan kategori meragukan sebanyak 12 bayi (40%). Hasil uji korelasi antara kadar EYU ibu dengan status perkembangan bayi menunjukkan p = 0,428; r = 0,150. Disimpulkan bahwa tidak terdapat hubungan yang bermakna antara kadar EYU ibu menyusui dengan status perkembangan bayi usia dibawah dua tahun.Disorders due to iodine deficiency (GAKY) in infants have an effect inhibit the growth and development processes. This study aims to determine the relationship of urinary iodine excretion (UIE) of breastfeeding mothers with the development of infants aged under two years in the endemic areas of GAKY. This research is observational with cross sectional design. The sample was 30 breastfeeding mothers with babies under two years old. Urinary iodine excretion levels were measured using Dry Digestion Ammonium Persulfate and Infant Development were assessed using a Pre-Screening Appraisal Questionnaire (KPSP). The maternal UIE median level was then correlated with the infant’s developmental status, using the Spearman test. The results showed that the mother’s UIE level was optimal (173,5 ppm). There were nine mothers (30%) had optimal UIE status, but infant development status in the dubious category of 12 (40%). Result of correlation test between mother UIE level with infant development status showed p = 0,428; r = 0.150. It was concluded that there was no significant association between UIE of breastfeeding mothers and developmental status of infants aged under two years.
Efek Antibakteri Ekstrak Daun Katuk (Sauropus androgynus) terhadap Pertumbuhan Salmonella Typhi secara In Vitro Sri Winarsih; Danik Agustin Purwantiningrum; Anastasia Shinta Wardhani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2015): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v15i2.3755

Abstract

Daun Katuk biasa digunakan sebagai obat tradisional terhadap berbagai macam penyakit termasuk mengobati diare. Kandungan daun Katuk yang diperkirakan berperan sebagai antibakteri adalah saponin, flavonoid dan tannin. Penelitian ini bertujuan untuk mengetahui efek antibakteri dari ekstrak daun Katuk secara in vitro. Metode yang digunakan adalah dilusi tabung yang terdiri dari dua tahap yaitu tahap penentuan Kadar Hambat Minimum (KHM) dan Kadar Bunuh Minimum (KBM). Konsentrasi ekstrak daun Katuk yang digunakan adalah 10%, 15%, 20%, 25% dan 30%, sedangkan konsentrasi S. typhi adalah 106 CFU/ml. Hasil menunjukkan bahwa KHM ekstrak daun Katuk terhadap S. typhi sebesar 25% dan KBM nya sebesar 30%. Uji Anova menunjukkan bahwa ekstrak daun Katuk secara signifikan menghambat pertumbuhan S. typhi (p = 0.000). Uji korelasi menggunakan regresi menunjukkan terdapat korelasi negatif  antara konsentrasi ekstrak daun Katuk dengan jumlah koloni S. typhi (p = 0,000; r = - 0,800). Dapat disimpulkan bahwa ekstrak daun Katuk memiliki efek antibakteri terhadap S. Typhi. Semakin tinggi kosentrasi ekstrak daun Katuk, semakin rendah jumlah koloni.Katuk (Sauropus androgynus) leaves is used as a traditional medicine against various diseases include diarrhea. The estimated antibacterial substances of Katuk leaves are saponin, flavonoid and tannin. The aim of this research is to know antibacterial effect of Katuk leaves extract against Salmonella typhi in vitro. Antibacterial effect is determined by tube dilution method, which consists of two steps, namely the determination of Minimum Inhibitory Concentration (MIC) and Minimum Bactericide Concentration (MBC). The concentrations of Katuk Leaves extracts are 10%, 15%, 20%, 25%, and 30%. The concentration of S. typhi is 106 CFU/ml. The result shows that MIC and MBC of the Katuk leaves extract are 25% and 30% respectively. Anova test shows that Katuk leaves extract significantly inhibits the growth of S. typhi (p = 0,000). Correlation test by using regression shows that there is a negative correlation between the Katuk leaves extract concentration and the amount of S. typhi colony (p= 0,000; r = - 0,800). The conclusion is that Katuk leaves has antibacterial effect against S. typhi. The higher concentration of Katuk leaf extract, the lower the number of colonies
Tingkat Pencemaran Escherichia coli pada Air Rumah Tangga di Wilayah Kerja Puskesmas Mijen, Semarang Kanti Ratnaningrum; Merry Tiyas Anggraini; Pujangga Puspito Yunus Dahlan
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2015): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v15i2.3756

Abstract

urangnya ketersediaan air bersih menimbulkan penyakit gangguan saluran pencernaan seperti diare. Sebagian besar bakteri penyebab diare adalah Escherichia coli. Insidensi diare dinilai masih jauh dari capaian target Puskesmas Mijen, Semarang. sehingga diperlukan penelitian tentang kontaminasi E. coli pada air rumah tangga di wilayah kerja Puskesmas. Penelitian ini bersifat observasional dengan rancangan cross sectional. Sampel ditentukan dengan  metode systematic random sampling dengan estimasi proporsi. Sampel diambil dari 10 kelurahan yang masuk dalam wilayah kerja. Kadar bakteri E. coli dalam air rumah tangga dilakukan di dengan metode most probable number (MPN). Terkumpul 36 sampel yang berasal dari 3 jenis sumber air yaitu sumur gali, sumur artesis dan perusahaan air minum (PAM). Uji laboratorium menunjukkan bahwa 55,6 % sampel air minum  telah memenuhi nilai uji bakteriologis E. coli. Air berasal dari sumur gali memiliki tingkat kontaminasi paling tinggi (100%) diikuti sumur artesis (34,61%) dan PAM bebas dari E. coli (0%).Lack of clean water supply causes gastrointestinal disorders such as diarrhea. Most of the bacteria that cause diarrhea are Escherichia coli. The incidence of diarrhea is still far from the target of Mijen Puskesmas, Semarang, so research on E. coli contamination on household water in Puskesmas work areas is needed. This research was observational with cross sectional design. The sample is determined by systematic random sampling method with estimated proportion. Samples were taken from 10 urban villages included in the work area. E. coli bacteria levels in household water are carried out in the most probable number (MPN) method. Collected 36 samples derived from 3 types of water sources ie dug wells, artesian wells and drinking water companies (PAM). Laboratory tests showed that 55.6% of drinking water samples had met the bacteriological test value of E. coli. Water derived from dug wells has the highest contamination rate (100%) followed by artesian well (34.61%) and PAM free from E. coli (0%).

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