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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
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Articles 5 Documents
Search results for , issue "Vol 19, No 2 (2019): July" : 5 Documents clear
Adaptation and Validation of Safety Attitude Questionnaire Ambulatory (SAQ-A) in Indonesian Primary Health Care Facilities Ngatoiatu Rohmani; Ike Winahyu Sari
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2 (2019): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190228

Abstract

Prevention of patient safety incidence needs to be pursued by the management committee of healthcare institutions by changing the behavior of healthcare providers to create a patient safety culture. Also, safety culture evaluation needs to be done to assess the implementation of the culture by healthcare providers. For this reason, a valid and reliable instrument is required in order to be accepted and used in Indonesia as a tool to measure of safety culture attitude in healthcare facilities. This study aimed to adopt the Safety Attitude Questionnaire – Ambulatory (SAQ-A) instrument to Indonesian. The study was carried out in 5 stages, they were: The translation stage, translation result synthesis, back-translated, review of 3 experts to obtain content validity index (CVI) and questionnaires trial which is conducted in 6 Puskesmas, i.e., Puskesmas Pandak I, Puskesmas Pajangan, Puskesmas Godean I, Puskesmas Kalasan, Puskesmas Tempel I and Puskesmas Minggir. Purposive sampling technique was selected to obtain 30 respondents based on inclusion criteria: She/he works in research location and has experience at least for one month, permanent/ contract employee, and not on sabbatical leave or other permission. Data were analyzed using the Content Validity Index (CVI) and Alpha Cronbach Coefficient. The validity test result of the Indonesian version of SAQ-A based on I-CVI and S-CVI was 1.00 with Cronbach’s alpha reliability value from the six dimensions in the questionnaire within range of α 0.612 – 0.881. The reliability test result of the full item on the Indonesian version of the SAQ-A questionnaire was α 0,914. It was concluded that the Indonesian version of the SAQ-A questionnaire is a valid and reliable questionnaire which can be used as a tool to measure safety culture attitudes of healthcare providers in primary healthcare facilities.
The Effect of Zam-zam Water to the Lipid Profile (HDL & LDL) at White Mouse (Rattus novergicus) Tama, Yhang Lidi; Sagiran, Sagiran
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2 (2019): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190231

Abstract

The estimates from the experts of the World Health Organization (WHO) indicate that 50% of the 12 million world population die from coronary heart disease blood vessel disease. Low-Density Lipid (LDL) and High-Density Lipid (HDL) ratios are often calculated to estimate the risk of coronary heart disease. Zam-zam water is thought to be efficacious in reducing blood lipid profile levels. This study aims to know the effect of Zam-zam Water on the lipid profile (HDL LDL) on a white mouse (Rattus Novergicus). The type of this research is an experimental laboratory design with a pre-post control group conducted for 28 days. The subjects of this study were 25 Rattus norvegicus wistar strains, divided into five groups namely control (aquades) group and four treatment groups (concentrations of 25%, 50%, 75% and 100%). The data were obtained by measuring the level of LDL and HDL before and after receiving the treatment of Cholesterol Oxidase Para Aminophenazone (CHODPAP). Also, the data were analyzed using ANOVA test and paired t-test. The Anova analysis showed that the administration of Zam-zam water affected the level of HDL and LDL as proven by the significance of differences among study groups (p 0.05). It is obtained that zam-zam water is 100% proven to have the most influence on HDL and LDL levels. The analysis of paired T-test showed that there were significant differences before and after treatment (p 0.05). Therefore, it can be concluded that the administration of zam-zam water affected the level of HDL and LDL of Rattus norvegicus blood lipid profiles.
Antioxidant Activity from the Combination of Ethanolic Extract of Tea Leaves (Camellia sinensis) and Soursop Leaves (Annona muricata l.) and Optimation of the Effervescent Granule Production Fatma Sari Masitha; Rifki Febriansah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2 (2019): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190230

Abstract

Soursop Leaves (Annona muricata L.) and Tea Leaves (Camellia sinensis) are plants that contain flavonoids which are considered to act as antioxidants and can become chemopreventive agents. This study aims to identify the potential of Soursop Leaves and Tea Leaves as chemopreventive agents. The first stage of this research was to determine the presence of flavonoids in both of ethanolic extract using TLC method. The second stage is to examine the antioxidant activity of the combination of ethanolic extract of soursop leaves and tea leaves against free radical DPPH (1,1-diphenyl-2-pikrihidrazil). Docking molecular test of acetogenin and catechin compounds at HER-2 and ER-α receptors which are biomarkers of breast cancer. Furthermore, the optimization of effervescent granule production using moist granulation method is carried out. The result shows that ethanolic extract of soursop leaves and tea leaves contains flavonoid shown with Rf value of 0.66 and 0.68, and the comparison of Rf 0.66. The combination of both ethanolic extract has very strong antioxidant activity with IC50 value 26,90 μg/mL. The result of molecular docking of acetogenin and catechin compounds at HER-2 receptors shows respective docking score of -6.3 kcal/mol and -6.7 kcal/mol while ER-α receptors shows a docking score of -6.5 kcal/mol and -7.6 kcal/mol. In addition, the most optimal effervescent granule production is formula four with physical test result such as moisture content of 1.07% with a dissolve time of 45.5 seconds and acidity of 6.18. The result shows that ethanolic extract of soursop leaf (Annona muricata L.) and Tea Leaves (Camellia sinensis) have potential activity as chemopreventive agents and can be formulated into effervescent granule production.
Social Demography Study of Gonorrhea and Syphilis at RSUD dr. Soedono Madiun Rahajeng Musy; Vita Widyasari; Rosmelia Rosmelia
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2 (2019): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190227

Abstract

An understanding of the socio-demographic characteristics is the first step to conduct preventive and promotive measures to reduce the number of sexually transmitted infections. This study described the socio-demographic cha-racteristics of gonorrhea and syphilis in dr. Soedono Hospital Madiun. A descripttive study with a quantitative approach used secondary data from outpatient medical records. This research was conducted in dr. Soedono Hospital Madiun, East Java. The samples used in this study were 61 patients who had been diagnosed with gonorrhea and syphilis in the period from July 2013 - June 2016. The data consisted of 50 (82%) medical records with the diagnosis of gonorrhea and 11 (18%) medical records with a diagnosis of syphilis. Characteristics of patients/respondents are the highest age group of 21-30 years, 22 female patients (36.1%), 55 male patients (90.2%), unmarried status 33 people (54.1%), work as private employees 37 people (60.7%), pay without insurance 48 people (78.7%), and live around Madiun 52 (86.0%). The socio-demographic factors were dominant in patients with gonorrhea and syphilis in dr. Soedono Hospital period of 2013-2016 was 21-30 years old, male, unmarried, living as private sector employees, pay without insurance, and Madiun origin.
Life Quality of Pediatric Patient with Dengue Hemorrhagic Fever (DHF) Who Received Crystalloid and Colloid Fluid Treatment in PKU Muhammadiyah Hospital Yogyakarta Chotijatun Nasriyah; Dyah Aryani Perwitasari; Nurcholid Umam Kurniawan
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2 (2019): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190229

Abstract

Dengue hemorrhagic fever (DHF) in the community can have an impact of panic, death, and reduced age of hope in the family. Research on the quality of life of DHF pediatric patient who got the treatment of crystalloid and colloid fluids has never been done before. The purpose of this study was to determine the quality of life of DHF pediatric patients who received crystalloids and colloids with PedsQL instruments. The study design was a cohort with block randomization. The inclusion criteria in this study were hospitalized DHF pediatric patients aged one month -18 years from February to May 2018. The exclusion criteria were DHF patients who came with referrals from other hospitals who had received fluid therapy. Research data include the length of stay (LOS) and quality of life score with the PedsQL questionnaire. The statistical analysis was using an independent t-test and the Mann Whitney test. The length of stay for the crystalloid group is five days longer than the colloid group, which is four days. From a total of 48 subjects studied, the score for the physical function of the crystalloid fluid group 84.54 ± 9.90 was higher than the colloid group of 77.58 ± 19.30 (p = 0.125). The emotional functions in the crystalloid group obtained a score of 81.88 ± 12.14 higher than the colloid group, i.e., 79.17 ± 18.5 (p = 0.552). The social function in the crystalloid group had a score of 92.08 ± 8.84 higher than the colloid group of 86.67 ± 13.96 (p = 0.232). The school functions in the crystalloid group had a score of 50.42 ± 33.68 higher than in the colloid group of 37.92 ± 36.62 (p = 0.225). The results of this study showed that the crystalloid group had a higher quality of life score compared to the colloid group, although it was not significant. 

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