Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan

kedokteran
Website

Published by Universitas Jambi

ISSN : 2339269X EISSN : 25806874 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Jambi Medical Journal is a Journal for Medical And Health Issues, in Scope: Medical Education, Farmakology, Mikrobiology, PUblic Health, Clinical Patology, Medical Nutrition, Clinical Medicine, Pediatric, Immunology, Patology Anatomi, Orthopedy, Obstetri and Gynekology, Internal Medicine, Endocrine and Metabolic, Genetics & Molecular Biology.

Arjuna Subject : -

Articles 380 Documents

7 8 9 10 11

BARRIERS OF FALL RISK ASSESSMENT AND PREVENTION IMPLEMENTATION IN HOSPITAL SETTING Gading, Patrick William
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 6 No. 2 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Falls are the most worrying incidence of patient safety concern that have an impact on injury and death. 1.9 to 3 percent of patients fall in the hospital, with injuries in 6 to 44 percent. Hospitals are making efforts to reduce those fall rates, but its implementation are hindered by a variety of barriers. This study aims to identify the barriers of fall risk assessment and prevention in the hospital. The research method is systematic review using PRISMA, with 15 included studies. Identified barriers includes insufficient knowledge, lack of motivation, absence of champion, lack of resources, inadequate communication, unsustainable program, and support and access shortage. To successfully implement fall prevention programs in hospitals requires a multifaceted, planned approach that includes: regular education and training for staff and patients; provision of equipment; audit, reminders and feedback; leadership and champions; simple programs; and a framework and time for adaptation in the hospital. Keywords: barriers, fall risk assessment, fall prevention, hospital

THE INFLUENCE OF VIDEO LEARNING MEDIA ADDITION ON NEUROMOTORIC PHYSICAL EXAMINATION CLINICAL SKILL OF MEDICAL STUDENT FACULTY OF MEDICINE AND HEALTH SCIENCES JAMBI UNIVERSITY
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 6 No. 2 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Background: Learning Clinical skills are one of the forms in learning on medical education curriculum which is aimed at improving ability of clinical skills and communication of medical students. Clinical Skill lab (CSL) is a tool for students to learn basic clinical skills whose training will not be detrimental and safe for patient. The addition of video learning media in clinical skills learning is one way to improve medical students clinical skills ability. Research Objectives: This study aims to see the effect of video learning media addition on neuromotoric Physical examination clinical skills of Medical students FKIK UNJA. Method: Experimental research with two groups post-test design only was held at PSKed FKIK UNJA in March-October 2017 and involving 128 students who underwent blok 1.2. The sample was divided into 2 groups and will get two different treatments. The first group had treatment in the form of CSL with was accompaniment by instructor and given the module. In the second group got the same treatment with the addition of a learning media in the form of a neuromotoric examination video. Influence of the treatment was assessed through a final evaluation of clinical skills in both groups Result: Based on the research result , the group of students who were given the addition of video learning media, has a higher average value (87.1) than the value average group of students who were not given video (80.3) and there is a significant difference in the value of the group of students receiving the video with the value of students who did not get video (p = 0.02) Conclusion: the provision of video learning media on CSL learning Blok 1.2 is quite effective in improving neuromotoric physical examination clinical skill of Medical students FKIK UNJA. Keywords: clinical skills, learning media, video, medical students

KEMAMPUAN CLINICAL REASONING PADA UJIAN OSCE MAHASISWA KEDOKTERAN TAHUN KETIGA
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background : Clinical reasoning is one of the clinical skill competencies that must be owned by a doctor so it needs to be studied and tested. The OSCE is one method of assessment that can be used to assess the achievement of clinical reasoning. OSCE in the third year at Faculty of Medicine Islamic University of Indonesia (FM IUI) has been using clinical case OSCE so that can be used to assess clinical reasoning skill in addition to others clinical skills such as physical examination and clinical procedural skills. This study aimed to evaluate the clinical reasoning skills of students in the third year of the OSCE exam at FM IUI. Methods : The cross sectional study method was used in this study. OSCE test result semesters 5 and 6 of the academic year 2015/2016 collected. Clinical reasoning skills of students in OSCE obtained from the score of the diagnosis ability in clinical case OSCE station. The difference between clinical reasoning skill on each OSCE station and its correlation with the written test on the corresponding block were analyzed. Results: There is differences between clinical reasoning skill in OSCE stations semester 5 and 6. There was no relationship between the score clinical reasoning skills at the OSCE with written test achievement on the corresponding block. Conclusion: The clinical reasoning skills on the OSCE semesters 5 and 6 do not illustrate the clinical reasoning skills of third-year medical students in this study. This study supports the need for further development of the assessment of clinical reasoning skills on the OSCE for medical students. Keywords : clinical reasoning, OSCE, medical student ABSTRAK Latar Belakang: Penalaran klinis atau clinical reasoning merupakan salah satu kompetensi keterampilan klinis yang harus dimiliki oleh seorang dokter sehingga perlu dipelajari dan diujikan. OSCE merupakan salah satu metode assessment yang dapat digunakan untuk menilai pencapaian clinical reasoning. OSCE pada tahun ketiga di FK UII telah menggunakan kasus klinis untuk dapat juga menilai clinical reasoning disamping keterampilan klinis yang lain seperti pemeriksaan fisik dan tindakan prosedural. Penelitian ini bertujuan mengevaluasi kemampuan clinical reasoning mahasiswa kedokteran pada ujian OSCE tahun ketiga di FK UII. Metode : Metode yang digunakan adalah cross sectional dari hasil ujian OSCE semester 5 dan 6 tahun akademik 2015/2016. Kemampuan clinical reasoning mahasiswa pada ujian OSCE didapatkan dari nilai kemampuan menegakkan diagnosis pada stasion OSCE yang berupa manajemen kasus klinis. Nilai OSCE direkap pada semua mahasiswa yang mengikuti ujian pada periode tersebut. Analisis dilakukan dengan melihat perbedaan kemampuan clinical reasoning antar station OSCE dan menilai korelasinya dengan ujian tulis pada blok yang bersesuain . Hasil: Terdapat perbedaan kemampuan clinical reasoning antar stasion OSCE baik di semester ke 5 maupun ke 6. Tidak terdapat hubungan antara nilai kemampuan diagnosis pada ujian OSCE dengan pencapaian nilai ujian tulis blok yang berkaitan dengan konten OSCE yang diujikan. Kesimpulan: Kemampuan diagnosis pada ujian OSCE semester 5 dan 6 tidak menggambarkan kemampuan clinical reasoning mahasiswa tahun ketiga pada penelitian ini. Diperlukan evaluasi dan pengembangan lebih lanjut mengenai penilaian dan pencapaian kemampuan clinical reasoning pada ujian OSCE bagi mahasiswa kedokteran. Kata kunci : clinical reasoning, OSCE, mahasiswa kedokteran

Hubungan Imunoekspresi Annexin V (ANX V) dengan Histopatologi Jaringan Kuretase pada Abortus Berulang
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background : Abortion the ending of pregnancy due to removing an embryo or fetus before it can survive outside the uterus. Examination on placental tissue currently does not provide much information. Annexin V (ANX V), formerly known as placenta anticoagulant protein and alpha coagulant vascular, is found in the placenta and vascular endothelium and several other tissues. This ANX V is found at the top of the placenta syncytiotrophoblast, and it is also found that this protein content freely decreases with the antiphospholipid syndrome (APS). This study aimed to assess the relationship between the description of ANX V expression and histopathology of curettage tissue in patients with recurrent abortion. Methods : This study was conducted using curettage tissue samples of patients with recurrent abortion in the Obstetrics and Gynecology section of Abdul Manap Hospital and Baiturahim Hospital in February to August 2018. The collected samples were diagnosed with HE preparations, to determine histopathological features in each group, villi infarction. hydrophic villi, sincytial knots, fibrin stroma and inter villi thrombus with the highest total score were 15. Then immunohistochemical assessment with Annexin V (ANX V) results compared with positive controls and negative controls with cut-off points 10%. Results: We have found a recurrent abortion sample with positive Annexin V immunoexpression, which is the most common histopathological score of 11-15 on recurrent abortion (p = 0.001 and r = -0.784) Conclusion: There is a relationship between immunohistochemistry ANX V with histopathological features of recurrent abortion curettage. Keywords: Annexin V, Histopathology, Recurrent abortion ABSTRAK Latar Belakang: Abortus adalah keadaan pengeluaran hasil konsepsi sebelum janin dapat hidup di luar kandungan. Pemeriksaan pada jaringan plasenta saat ini tidak banyak memberikan informasi. Annexin V (ANX V), dulu dikenal dengan placental anticoagulant protein I dan vascular coagulant alfa, ditemukan di plasenta dan endotel vaskular dan beberapa jaringan yang lain. ANX V ini ditemukan di puncak permukaan sinsitiotrofoblas plasenta, dan ditemukan pula bahwa kadar protein ini secara bermakna menurun di villi plasenta penderita abortus dengan antiphospholipid syndrome (APS). Penelitian ini bertujuan melihat hubungan gambaran ekspresi ANX V dengan histopatologi jaringan kuretase pada penderita abortus berulang. Metode : Penelitian ini dilakukan dengan menggunakan sampel jaringan kuretase pasien abortus berulang di bagian Obstetri dan Ginekologi RS Abdul manap dan RS Baiturahim periode februari sampai agustus 2018. Sampel yang terkumpul dilakukan diagnosis terhadap sediaan HE, untuk menetukan gambaran histopatologis pada masing-masing kelompok yaitu infark villi, hidrofik villi, sincytial knots, fibrin stroma serta trombus inter villi dengan skor total tertinggi adalah 15. Kemudian dilakukan pemulasan dan penilaian imunohistokimia dengan Annexin V (ANX V) Hasil pulasan imunohistokimia Anti ANX V dibandingkan dengan kontrol positif dan kontrol negative dengan cut-off point 10%. Hasil: Didapatkan 30 sampel abortus berulang dengan imunoekspresi Annexin V positif, didapatkan paling banyak dengan skor histopatologi 11- 15 pada abortus berulang (p = 0.001 and r = -0.784). Kesimpulan: Terdapat hubungan antara imunohistokimia ANX V dengan gambaran histopatologi pada kuretase abortus berulang. Kata Kunci: Annexin V, Histopatologi, Abortus berulang

THE HIGH DOSE TOXICITY OF BETEL NUT (Areca catechu L.) ON REPRODUCTION ORGAN OF RATS
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background : The use of long-term herbal medicines and high doses can damage organs, including the reproductive organs. Betel nut (Areca catechu L.) is one of the herbal ingredients that is consumed as a stamina enhancing beverage. The purpose of this study was to determine the effect of longterm treatment of raw betel nut at a dose of 10,000 mg/kg on testicular and ovary tissue of rats. Rats were Rattus norvegicus, Sprague Dawley strain, 2-3 months. Methods : Tweenty rats divided into 2 groups, each groups were 5 male and 5 female. Control group was given aquades and the treatment group was given raw betel nut with a dose of 10,000 mg/kgBW for 45 days with a gastrictube. Histopathological examination with Haematoxylin-Eosin staining was used to assses testicular and ovary tissues. Results: The ovaries of treatment groups had significantly lower de graff follicle compared to the control group (p < 0,05). The testis of treatment groups had significantly smaller diameter of tubulus seminifery, significantly higher necrosis of spermatogonia and spermatosit (p<0,05). Conclusion: Treatment of raw betel nut dose 10,000 mg /kgBW along 45 days causes damage of testicular and ovary tissues of rats.Keywords: Betel Nut, Areca Catechu L., Histopathology, Testicular, Ovary, Herbal Toxicity ABSTRAK Latar Belakang: Pemakaian obat herbal jangka panjang dan dosis tinggi dapat menyebabkan kerusakan organ tubuh, termasuk organ reproduksi. Biji pinang (Areca catechu L.) merupakan salah satu bahan herbal yang dikonsumsi sebagai minuman penambah stamina.Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian biji pinang muda dosis 10.000 mg/ kgBB selama 45 hari terhadap gambaran histopatologis testis dan ovarium tikus. Metode : Tikus yang digunakan adalah Rattus norvegicus galur Spague Dawley, usia 2-3 bulan, sebanyak 10 ekor jantan dan 10 ekor betina yang dibagi menjadi 2 kelompok, yaitu kelompok kontrol diberikan aquades dan kelompok perlakuan diberikan biji pinang dosis 10.000 mg/ kgBB dengan sonde. Pemeriksaan histopatologi dengan pewarnaan Haematoxylin-Eosin untuk organ testis dan organ ovarium. Hasil: Jumlah folikel de draf pada kelompok perlakuan lebih sedikit dibandingkan kelompok kontrol (p<0,05). Persentase nekrosis spermatogonia dan spermatosit pada kelompok perlakuan lebih tinggi dibandingkan kelompok kontrol (p<0,05), diameter tubulus seminifeus pada kelompok perlakuan juga lebih kecil dibandingkan kelompok kontrol (p<0,05). Kesimpulan: Pemberian biji pinang 10.000 mg/kgBB selama 45 hari menyebabkan kerusakan pada jaringan testis dan ovarium pada tikus. Kata Kunci : Biji Pinang, Areca Catechu L, Histopatologi, Ovarium, Testis, Toksisitas herbal

Hyperosmolar Hyperglycemic State (HHS)
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACK Introduction: The Hyperosmolar Hyperglycemic State (HHS) is rare case and the most serious acute hyperglycemic emergency in patients with type 2 diabetes, are characterized by severe hyperglycemia, hyperosmolality, and dehydration in the absence of ketoacidosis. Immediately treatment is necessary to reinstate hemodynamic stability, as mortality rates for HHS are exceptionally high and can have multiple complications. Case Presentation: In this case report, a 63-year-old man with a chiefly complaint from the body became weaker. Patients present with compos mentis, blood pressure 100/70 mmHg, regular pulse rate 110 times per minute with sufficient content and respiration 20 times per minute, and temperature 37,90C. Physical examination shows signs of dehydration. Investigation found white blood cell 12.580 103/mm3, plasma glucose 741 mg / dL, and a negative urine ketone. Conclusion: Case has been reported, a 63-year-old man with a diagnosis of HHS, the trigger factor for HHS in these patient are the discovery of infections as bronchopneumonia, elderly, and irregular diabetes treatment. The importance of treatment in this case is because the patient is elderly, treatment must be right because where too rapid rehydration may precipitate heart failure but insufficient may fail to reverse acute kidney injury. Keywords: Diabetes Mellitus, Hyperosmolar Hyperglycemic State, Hyperglycemia ABSTRAK Latar Belakang : Hyperosmolar Hyperglycemic State (HHS) merupakan kasus yang jarang dan komplikasi emergensi akut dari pasien diabetes melitus tipe 2, dengan karakteristik hiperglikemi, hiperosmolar dan dehidrasi atau tidak adanya ketoasidosis. Tatalaksana segera penting dilakukan untuk menstabilkan hemodinamik, mortalitas dari HHS tinggi dan dapat menyebabkan banyak komplikasi. Presentasi Klinis : Pada laporan kasus ini, seorang laki-laki berusia 63 tahun dengan keluhan utama badan semakin lemas. Pasien datang dengan kesadaran kompos mentis, tekanan darah 100/70 mmHg, nadi teraba 110 kali per menit kuat regular dengan isi cukup dan respirasi 20 kali per menit, dan suhu 37,90C . Pemeriksaan fisik didapatkan tanda-tanda dehidrasi. Pemeriksaan penunjang dijumpai sel darah putih 12.580, glukosa plasma 741 mg/dL, dan keton urine negatif. Kesimpulan : Telah dilaporkan kasus, laki-laki usia 63 tahun dengan diagnosa HHS, faktor pencetus terjadinya HHS pada pasien ini yaitu ditemukannya infeksi berupa bronkopneumonia, usia lanjut, pengobatan diabetes yang tidak teratur. Pentingnya perawatan dalam kasus ini adalah karena pasien berusia lanjut, pengobatan harus benar karena ketika rehidrasi yang terlalu cepat dapat memicu gagal jantung tetapi tidak cukup dapat gagal untuk membalikkan cedera ginjal akut. Kata Kunci : Diabetes Melitus, Hyperglycemic Hyperosmolar State, Hiperglikemi

STUDI KASUS: OBSERVASI PENERAPAN METODE BEDSIDE PADA PROSES BEDSIDE TEACHING DI BANGSAL PENYAKIT DALAM RUMAH SAKIT SARDJITO YOGYAKARTA
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Bedside teaching is an excellent opportunitiy for spontaneuous interaction between student, clinical supervisor, and patient. In bedside teaching sessions there are possibilities for appropriate and inappropriate encounter. Clinical supervisor observes and gives feedback in order to create a useful bedside teaching session for student. Bedside teaching session observed in Internal Ward of Sardjito Hospitol has applied Briefing, Expectation, Demonstration, Specific feedback, Inclusion of microskill teaching, Debriefing and Education accordingly. Student has obtained optimal learning opportunity from the event. Keywords: Bedside teaching, clinical, feedback ABSTRAK Bedside teaching adalah suatu kondisi yang baik untuk interaksi yang spontan antara mahasiswa, pembimbing klinik, dan pasien. Dalam sesi Bedside teaching terdapat kemungkinan terjadi prosedur yang sesuai ataupun yang kurang sesuai. Seseorang pembimbing klinik berperan untuk mengamati dan memberi umpan balik sehingga dapat menjadi sesi bedside teaching yang berguna bagi mahasiswa. Pelaksanaan Bedside teaching di Bangsal Penyakit Dalam RS Sardjito menerapkan tahapan Briefing, Ekspektasi, Demonstrasi, Umpan balik spesifik, Penerapan pengajaran microskill, Debriefing, dan Edukasi telah diterapkan dengan baik. Mahasiswa memperoleh manfaat yang optimal dari proses tersebut. Kata kunci: Bedside teaching, klinik, umpan balik

KADAR INTERFERON GAMMA (IFNγ) PADA PASIEN TOKSOPLASMOSIS YANG ASIMPTOMATIK
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Toxoplasma gondii is a species that is able to modulate its host immune system. T.gondii infection causes an increased Th1 response to produce IFNγ, TNFα and IL-12 secreted by T. IFNγ lymphocytes which are activated and cause increased production of Nitric Oxide (NO) which can cause cell apoptosis and IFNγ can destroy T.gondii with several mechanisms. The aim of this study was to determine IFN levels in patients with positive IgG and asymptomatic IgG toxoplasmosis.Methods: Case control research with experimental laboratories that use human blood as the object of research. The subjects were initially checked for blood with IgG Rapid Test to determine the positive or negative Toxoplasma infection. IFNγ levels are checked by the ELISA method. To analyze the average comparison of IFNγ levels using computer software. Test the data normality with Saphiro-wilk and comparison of IFNγ levels with Wilcoxon test.Results: IFNγ levels in the negative IgG group (4.69) were slightly lower on average compared to the positive IgG group (4.79). Wilcoxon test results of p> 0.05 (0.399) means that the hypothesis is rejected.Conclusion: There was no difference between IFNγ levels in the positive IgG group and the negative IgG group.Keywords: Toxoplasmosis, IFNγ level, IgG toxoplasmosis. ABSTRAK Latar belakang: Toksoplasma gondii merupakan spesies yang mampu memodulasi sistem imun inangnya. Infeksi T.gondii menyebabkan respon Th1 meningkat untuk memproduksi IFNγ, TNFα dan IL-12 yang disekresi oleh sel limfosit T. IFNγ diaaktifkan dan menyebabkan meningkatnya produksi Nitric Oxide (NO) yang bisa menyebabkan apoptosis sel dan IFNγ bisa memusnahkan T.gondii dengan beberapa mekanisme. Tujuan penelitian ini untuk menentukan kadar IFNγ pada pasien IgG positif dan IgG Toksoplasmosis yang asimptomatik. Metode: Penelitian case control dengan eksperimental laboratorik yang mengunakan darah manusia sebagai objek penelitian. Subjek awalnya di cek darahnya dengan Rapid Test IgG untuk menentukan positif atau negatif infeksi toksoplasma. Kadar IFNγ dicek dengan metode ELISA. Untuk menganalisa perbandingan rerata kadar IFNγ menggunakan perangkat lunak komputer. Uji normalitas data dengan Saphiro-wilk dan perbandingan kadar IFNγ dengan uji Wilcoxon. Hasil: Kadar IFNγ pada kelompok IgG negatif (4,69) rata-rata lebih rendah sedikit dibandingkan dengan kelompok IgG positif (4,79). Uji Wilcoxon hasil p>0,05 (0,399) artinya hipotesis ditolak. Kesimpulan: Tidak ada perbedaan antara kadar IFNγ pada kelompok IgG positif dengan kelompok IgG negatif. Kata Kunci : Toksoplasmosis, Kadar IFNγ, IgG Toksoplasmosis

HUBUNGAN ANTARA KADAR TGF-Β1 DENGAN KADAR ALBUMIN DALAM URIN PASIEN DM TIPE-2 DENGAN NEFROPATI DIABETIK
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Diabetic nephropathy (DN) is a complication of diabetes in the kidney that frequently causes terminal kidney disease. This kidney disease caused by diabetes is a syndrome characterized by albumin in urine (albuminuria). Growth factor-β1 (TGF- β1) is a multifunctional cytokine that controls many biological processes, including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, adipogenesis, and osteogenesis. Previous studies had showed that TGF-β1 plays a role in albuminuria, where TGF-β1 expression in the kidney increases in diabetes patients. Elevation of cytokine level, especially transforming growth factor beta-1 (TGF-β1) that induces the increase of several extra cellular matrices (ECM), i.e. fibronectin, integrin-linked kinase (ILK) and type IV collagen. This TGF-β1 activity causes the accumulation of ECM, which leads to thickened glomerular basement membrane (GBM). Thickening of GBM and changes in kidney structure in the form of hypertrophy and reduced glomerular podocytes caused by apoptosis and attachment in GBM causes protein components to exit through urine (albuminuria). This study aimed to prove the correlation between transforming growth factor-β1 and albumin level in urine of diabetic nephropathy. Metode : This study a observasional with desain Cross-sectional comparative study. Results: Mean TGF-β1 level in type 2 DM patients with diabetic nephropathy in this study was 47.30 ± 14.70 ng/ml, with similar value between men and women with 43.1 ng/ml and 44.7 ng/ml, respectively. Out of 60 type 2 DM participants with ND, the mean albuminuria level according to ACR was 722.53 ± 1854.96 mg/g. The result of male participants was lower compared to female participants, with 667.8 mg/mg and 777.2 mg/g, respectively. Conclusion: There was insignificant correlation between TGF-β1 in diabetic nephropathy (DN) and albumin level in urine measured using albumin and urine creatinine ratio (ACR) (p = 0.066). Keywords: Diabetic Nephropathy, Albuminuria, TGF-β1 ABSTRAK Latar Belakang : Nefropati diabetik (ND) merupakan komplikasi diabetes pada ginjal yang paling sering menyebabkan terjadinya penyakit ginjal terminal. Penyakit ginjal akibat diabetes ini merupakan sindroma dengan karakteristik terdapatnya albumin dalam urine (albuminuria). Faktor pertumbuhan-β1 (TGF-β1) adalah sebuah sitokin multifungsi yang mengendalikan banyak proses biologis termasuk kekebalan, diferensiasi, tumor supresi, tumor metastasis, penuaan, migrasi, penyembuhan luka, apoptosis, adipogenesis, dan osteogenesis. Sejumlah penelitian sebelumnya menunjukkan bahwa TGF-β1 berperan terhadap terjadinya albuminuria, dimana pasien diabetes didapatkan ekspresi TGF-β1 di ginjal meningkat. Peningkatan kadar cytokine terutama Transforming Growth Factor Beta-1 (TGF-β1) yang menginduksi peningkatan beberapa Extra Cellular Matrix (ECM) antara lain fibronectin, integrin-linked kinase (ILK) dan collagen tipe-IV. Aktifitas TGF-β1 ini menyebabkan akumulasi ECM sehingga terjadi penebalan Glomerular Basement Membrane (GBM). Penebalan dari GBM dan terjadinya perubahan struktur ginjal berupa hipertrofi dan berkurangnya sel-sel podocyte glomerulus akibat kerusakan (apoptosis) dan perlengketan di GBM menyebabkan komponen protein keluar melalui urin (albuminuria). Tujuan penelitian ini untuk membuktikan hubungan antara kadar transforming growth factor-β1 dengan kadar albumin dalam urin pada Nefropati Diabetik. Metode : Penelitian ini merupakan penelitian Observasional dengan desain Cross-sectional comparative study. Hasil : Kadar rata-rata TGF-β1 pasien DM tipe-2 dengan Nefropati Diabetik pada penelitian ini adalah 47,30 ± 14,70 ng/ml, tidak jauh berbeda antara laki-laki yaitu 43,1 ng/ml dengan perempuan 44,7 ng/ml. Dari 60 orang responden DM tipe-2 dengan ND pada penelitian ini didapatkan kadar albuminuria rata-rata berdasarkan ACR adalah 722,53 ± 1854,96 mg/g. Responden laki-laki lebih rendah dibanding perempuan yaitu 667,8 mg/g berbanding 777,2 mg/g. Kesimpulan : Tidak terdapat hubungan yang bermakna antara TGF-β1 pada Nefropati Diabetik (ND) dengan kadar albumin dalam urin yang dihitung berdasarkan rasio albumin dan creatinin urin (ACR) (p=0,066). Kata Kunci : Nefropati Diabetik, Albuminuria, TGF-β1

Supervisi Klinik Stase Mayor Pada Rumah Sakit Pendidikan Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Clinical phase in medical education is education that carried out through the teaching and learning process in the form of clinical and community learning that employs various forms and levels of health services. At clinical phase learning , students are given the opportunity to be involved in health services with the guidance and supervision of clinical supervisors. Clinical supervision has a positive impact on patient health and the knowledge development of medical students. Research Objective: This study aims to determine the clinical supervision overview in the major stage at Teaching Hospital of Faculty of Medicine and Health Sciences Jambi University based on student perceptions. Method: This research is a combination of quantitative research and qualitative research. Quantitative research conducted was a cross sectional study using the Clinical Teaching Effectiveness Instrument (CTEI) questionnaire. The usage of the CTEI questionnaire in this study was to find out the clinical supervision overview in the major stage at Teaching Hospital based on student perceptions. Furthermore, qualitative research was conducted with focus group discussions (FGD) to confirm and explore the perceptions of the students based on the results of questionnaire analysis. Results: Overall, for every 15 items of clinical supervision in each major stage had a mean CTEI score > 3 with a score range of 3.6- 4.1. Range of scores on the Internal Medicine Department 3.2 - 4.7; Pediatric Department 3.4 - 3.8; Surgery Department 3.6 - 4 and Obgyn Department 3.7- 4. Conclusion: Based on the results, it can be concluded that the clinical supervision of the major stages at Teaching Hospital of Faculty of Medicine and Health Sciences Jambi University has been run well. Keywords: clinical supervision, CTEI, medical students ABSTRAK Latar Belakang: Pendidikan kedokteran fase klinik adalah pendidikan kedokteran yang dilaksanakan melalui proses belajar mengajar dalam bentuk pembelajaran klinik dan pembelajaran komunitas yang menggunakan berbagai bentuk dan tingkat pelayanan kesehatan nyata. Pada pembelajaran fase klinik mahasiswa diberi kesempatan terlibat dalam pelayanan kesehatan dengan bimbingan dan pengawasan supervisor klinik . Supervisi klinik memiliki dampak yang positif terhadap kesehatan pasien dan perkembangan pengetahuan mahasiswa kedokteran. Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui gambaran supervisi klinik di stase mayor Rumah Sakit pendidikan Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi berdasarkan persepsi mahasiswa Metode: Penelitian ini merupakan gabungan antara penelitian kuantitatif dan penelitian kualitatif. Penelitian kuantitatif yang dilakukan merupakan, studi cross sectional dengan menggunakan kuesioner Clinical Teaching Effectiveness Instrument (CTEI). Penggunaan kuesioner CTEI pada penelitian ini untuk mengetahui gambaran supervisi klinik di stase mayor Rumah Sakit pendidikan berdasarkan persepsi mahasiswa. Selanjutnya dilakukan penelitian kualitatif dengan diskusi kelompok terfokus (DKT) untuk mengkonfirmasi dan mengeksplorasi persepsi mahasiswa tersebut berdasarkan hasil analisis kuesioner Hasil: Secara keseluruhan untuk setiap 15 item supervisi klinik di setiap bagian mayor memiliki rerata skor CTEI > 3 dengan rentang skor 3.6- 4.1. Rentang skor pada Bagian Ilmu penyakit Dalam 3.2 – 4.7; Bagian Ilmu kesehatan anak 3.4 – 3.8; Bagian Ilmu Bedah 3.6 – 4 dan Bagian Obgyn 3.7- 4. Kesimpulan: Berdasarkan hasil penelitian dapat disimpulkan bahwa supervisi klinis stase mayor di Rumah Sakit Pendidikan Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi telah berjalan dengan baik. Kata kunci: supervisi klinik, CTEI, mahasiswa kedokteran

Page 9 of 38 | Total Record : 380

7 8 9 10 11

Filter by Year

2013 2025

Filter By Issues

All Issue Vol. 13 No. 2 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan Vol. 12 No. 2 (2024): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan Vol. 12 No. 1 (2024): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan Vol. 11 No. 4 (2023): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 11 No. 3 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Special Issues: Jambi M Vol. 11 No. 2 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Special Issues: Jambi M Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Vol. 10 No. 4 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Vol. 10 No. 3 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Vol. 10 No. 2 (2022): Special Issues: Jambi Medical And Health Sciences International Conference (JA Vol. 10 No. 1 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Vol. 9 No. 1 (2021): Special Issues: JAMHESIC 2020 Vol. 9 No. 3 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 9 No. 2 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 8 No. 2 (2020): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 8 No. 1 (2020): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 7 No. 2 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 7 No. 1 (2019): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 6 No. 2 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 6 No. 1 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan Vol. 5 No. 2 (2017): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 5 No. 1 (2017): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 4 No. 2 (2016): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 4 No. 1 (2016): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 3 No. 2 (2015): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 3 No. 1 (2015): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 2 No. 1 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan Vol. 1 No. 2 (2013): THE JAMBI MEDICAL JOURNAL Vol. 1 No. 1 (2013): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota jambi,

Jambi

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota jambi, Jambi INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota jambi,

Jambi

INDONESIA