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Saka Winias
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INDONESIA
Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
Arjuna Subject : -
Articles 13 Documents
Search results for , issue "Vol. 57 No. 2 (2024): June" : 13 Documents clear
Review of salivary antioxidants and their barriers Nelson, Ashlianne; Santosh, Arvind Babu Rajendra; Jones, Thaon
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p74-79

Abstract

Background: Oxidative stress results from the imbalance between reactive oxygen species (ROS) and cellular antioxidant defenses. Oxidative stress can cause damage to cellular structures such as cell membranes, lipids, proteins, lipoproteins, and deoxyribonucleic acids when free radicals are present in excess. Antioxidant mechanisms protect tissues against oxidative stress by decreasing free radical levels in cells through the inhibition of activities or expression of free radical-generating enzymes. Purpose: The purpose of this paper is to discuss the role of antioxidants in protecting cells from the harmful effects of ROS, particularly in the context of oral mucosa, and to clarify which molecules disrupt the pathway of these antioxidants. Review: Salivary peroxidase, catalase, superoxide dismutase, and glutathione reductase are enzymatic salivary antioxidants, and uric acid, reduced glutathione, albumin, and lactoferrin are non-enzymatic antioxidants. Both types of antioxidants regularly donate an electron to free radicals to reduce their levels in cells. Conclusion: Antioxidant activities may be disrupted by signaling mechanisms resulting from barrier regulations observed in tissue. The increased expression of malondialdehyde is an indicator of disrupted antioxidant barriers.
The effect of 5% Curcuma xanthorrhiza extract gel on diabetic rat socket: A fibroblast analysis Anggayanti, Nyoman Ayu; Purbasari, I Gusti Ayu Kade Ira; Wahyuni, Putu Sinta Elix
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p124-130

Abstract

Background: Predominant advanced glycation end products (AGEs) in diabetes mellitus (DM) patients lead to increased reactive oxygen species, causing oxidative stress and cell apoptosis, which hinders wound healing. Curcuma xanthorrhiza contains active compounds such as curcumin, flavonoids, and saponins, which can increase fibroblast cell production, the primary indicator of wound healing, and serve as AGE inhibitors. Purpose: This study aimed to determine the effect of 5% C. xanthorrhiza extract gel on the number of fibroblasts in diabetic Wistar rats during the healing of tooth extraction over a specific duration. Methods: The left mandibular incisor was extracted after using alloxan to induce diabetes in the rats. The socket was then treated with different compounds, including 5% C. xanthorrhiza extract gel, placebo CMC-Na, or Gengigel. A histopathological examination of the socket was conducted to assess the presence of fibroblasts on days one, three, and five after treatment. Results: The number of fibroblasts in the sockets treated with 5% C. xanthorrhiza extract gel was lower than in the Gengigel group but higher than in the placebo group (p < 0.05). Conclusion: 5% C. xanthorrhiza extract gel can increase the number of fibroblasts, thereby potentially accelerating wound healing in DM.
Full-mouth rehabilitation in a patient with multiple caries: A case report Putra, Anak Agung Istri Devi Wulandari; Yolanda, Yolanda
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p152-157

Abstract

Background: Full-mouth rehabilitation of multiple caries can improve the quality of life. The selection of appropriate restorations on caries and teeth that have undergone post-endodontic treatment is critical to treatment success and enhances the quality of life. Purpose: This case report presents a full-mouth rehabilitation of a patient with multiple caries. Case: A 30-year-old man complained of multiple caries and pain in the posterior mandibular tooth, especially when eating and drinking (cold and hot), which interfered with his activities. The clinical examination found caries in teeth 16, 22, 24, 25, 26, 27, 36, 37, and 38 and a retained root of tooth 46. The percussion and biting tests were negative, while the sensibility test was positive. Case Management: Severe caries found in tooth 37 was managed with endodontic treatment and an indirect onlay restoration with lithium disilicate-based material. The retained tooth of 46 was extracted and restored with a partial denture. The other teeth, 16, 22, 24, 25, 26, 27, 36, 37, and 38, were treated by direct composite restoration. Holistic treatment was performed on all the problem teeth to support oral hygiene and was followed by dental health education. Conclusion: Full-mouth rehabilitation is essential for oral hygiene and can improve the quality of life. Education on maintaining oral hygiene is a must for protecting oral health.

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