cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota denpasar,
Bali
INDONESIA
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES
Published by Universitas Udayana
ISSN : 20854773     EISSN : 23022906     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesia Journal of Biomedical Science (IJBS), Print-ISSN 2085-4773; E-ISSN 2302-2906 is an international and peer-reviewed journal published twice per year in print and online by Indonesian of Biomedical Association in collaboration to Postgraduate School of Biomedicine Udayana University, Bali-Indonesia which was founded in 2007. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of biomedical scholarship, and to encourage a vigorous dialogue between biomedical scholars and researches. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and biomedical researchers all over the world.
Arjuna Subject : -
Articles 6 Documents
 1 
Search results for , issue "Vol. 5, No. 1 Januari 2011" : 6 Documents clear
CHANGING BODY POSTURE AND WORKING SYSTEM IMPROVES WOKERS PERFORMANCE AND PRODUCT QUALITY Surata, I Wayan; Manuaba, A.; Adiputra, N.; Sutjana, D.P.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.544 KB)

Abstract

Seaweed is one of the nation’s potential marine commodities that maycontribute to the national revenue and a new source of income for the localcommunity, as the cultivation of seaweed is much easier and cheaper than paddycrop, because neither pesticides nor fertilizer would be required. Other advantages ofcultivating seaweed are the fact that it can be carried out throughout the year, and itsrelatively shorter duration to reach the harvesting time. Local practice of drying theseaweed is by spreading it over a plastic sheet on the ground and exposing it to thesun. Unfortunately, such traditional practice of drying seaweed has led to increasedrisk of contamination of seaweed by dust and sand particles and other impurities.The quality of seaweed is influenced by the type of seedlings, harvesting age, andthe crucial process of drying. The local traditional working posture during drying issquatting and stooping to flatten and spread evenly the seaweed. Our preliminarystudy has shown that the farmers have had considerable musculoskeletal complaintsand fatigue with the seaweed quality being still relatively low.This study was conducted to examine the effects of changing the workers’working posture and limiting lift weight at 23 kg and introduced a 5-minute breakafter an-hour work with the aim to improve both workers’ performance and seaweedquality and productivity. This is an experimental study using a two-period crossoverdesign on 20 farmers of seaweed cultivation in the Ped Village of Nusa Penida.The results of our study showed that redesigning and changing the workers’working posture and working system improved the performance of seaweed farmersas revealed by the decrease of musculoskeletal complaints to 56.15% (p < 0.05); bydecrease in general fatigue to 50.84% (p < 0.05); by the increase in productivity to37.93% (p < 0.05), and by the increase in income to 41.62% (p < 0.05). The qualityof the dried seaweed was also improved as could be seen from the decrease in watercontent to 29.24% (p < 0.05) and decrease in impurities to 33.33% (p < 0.05).From our data it could be inferred that changing the workers’ working bodyposture and working system significantly improved both their performance and thequality of their product.
CENTELLA ASIATICA EXTRACT INCREASED ON THE LEVEL OF INTERLEUKIN 6 (IL-6) IN MICE Kerta Besung, I Nengah; Mantik Astawa, Nyoman; Suatha, I Ketut; -, Hartaningsih
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (88.36 KB)

Abstract

Salmonellosis is still problem in many developing countries including Indonesia. Themain problem in controlling and handling the disease is that only few antibiotics are availableto cure the disease. In addition, the prolonged use of such antibiotics often lead to bacterialresistant against the antibiotics. A herbal drugs such as Centella asiatica (in Indonesia isknown as pegagan) contains triterphenoid saphonins which acts as immunostimulant capableof enhancing the phagocytic activity of macrophages. However, no study has been conductedto investigate the use pegagan in activating macrophage of mice infected with Salmonellatyphi. A study was therefore conducted to find out the ability of Cantella asiatica inenhancing on the level interluekine (IL)-6 following challenge with Salmonella typhi. It istherefore expected that herbal drug such as Cantella asiatica can be used as an alternativemedicine to prevent and cure salmonellosis in both animals and human.Experimental laboratory studies were conducted using Completely FactorialRandomized Design. Mice were divided into 4 groups and they were treated respectively withdestilated water (negative control), 125, 250, and 500 mg/kg bw of Centella asiatica extract.The treatment was conducted daily for 2 weeks and the mice were then inoculated with 105cells of S. typhi. The level of IL-6 response were examined 24 hours, 2 weeks, and 4 weeksafter inoculation with S. typhi.The result showed that treatment of mice with Centella asiatica extract significantly(p<0,05) enhaced IL-6 level of Balb/c mice following inoculation with S. typhi. The highestIL-6 level were observed in mice treated Centella asiatica extract at the dose of 500 mg/kgBW (385,9257±125,4314 pg/ml serum). And the highest IL-6 level were observed at 2 weeksfollowing inoculation with S. typhi (533.4262 ± 81.7184 pg / ml).A further study is recomended to examine the celluler immune response and moredetailed study on the humoral immune response of animals or human before this herbal isused as alternatif medicine to prevent and cure typhoid fever. It is also important to study thebest preparation, the half life, and the side effect of Centella asiatica in human and animals.
THE HIGH PLASMA RETINOL BINDING PROTEIN 4 LEVEL AS A RISK FACTOR CONSEQUENTLY OF TYPE 2 DIABETES MELLITUS OF ABDOMINAL OBESITY Budhitresna, AAG; Suastika, Ketut; Mantik Astawa, Nyoman; Santoso, Anwar
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.463 KB)

Abstract

Abdominal obesity (Ab-Ob) related to cardiometabolic risk, that is riskfactor constellation for succeeded cardiovasculer disease and type 2 DiabetesMellitus (DM). That factors such as atherogenic dislipidemia, hypertension,hyperglycemia, protrombotic state, and proinflammation state. Type 2 DMcharacterised by insulin resistance (IR). Plasma levels of retinol binding protein 4(RBP4) that is secreted by adipocytes are increased in insulin resistance (IR) state.Experiment in mice suggest that elevated RBP4 level cause IR. Although theunderlying mechanism is not clearly understood, RBP4 considered playimportance role consequently of type 2 DM in Ab-Ob.This research was carried out to determine the role of high plasma RBP4level as a risk factor consequently of type 2 DM in Ab-Ob. The research wasconducted by cross sectional analytic in 81 patients with Ab-Ob and case controlstudy with matching on 33 patients with Ab-Ob type 2 DM as cases and 33patients with Ab-Ob non type 2 DM as control. The plasma of TNF-?, sTNFR1,and RBP4 levels was measured by ELISA. IR status of the patients wasdetermined by HOMA-IR, whereas the ?-cell function was determined byHOMA-B. Ab-Ob was defined by using criteria for Asian peoples (male WC ? 90cm; female WC ? 80 cm). The result of 81 patients with Ab-Ob showed that bothplasma of TNF-? and sTNFR1 levels were significant positive correlated withplasma RBP4 level (coeficient correlation r = 0,294; p = 0,008 dan r = 0,458; p =<0,001 respectively). In addition, the plasma of RBP4 level significantly positivecorrelation with HOMA-IR (r = 0,450; p = 0,000) and significantly negativecorrelation with HOMA-B (r = -0,564; p = <0,001). In the matched case-controlstudy, it was shown that mean plasma of RBP4 level of type 2 DM group (76,08 ±16,84 ?g/ml) statistically higher than that without type 2 DM group (41,13 ±14,75 ?g/ml) (p = <0,001). The odds ratio higher plasma of RBP4 level was 5,426(CI 95%; 1,343 – 21, 928) statistically significant for increases risk type 2 DM (p= < 0,05). It has been proven that RBP4 was a dominant and consisten risk factor(66.9%, p = < 0.001) which influenced the incidence of type 2 DM in Ab-Ob. It can be concluded that high plasma of RBP4 level have a greater risk tosuffered from type 2 DM compared to low plasma of RBP4 in Ab-Ob. The highplasma of RBP4 level is most dominant and consistent risk factor consequently oftype 2 DM. These mechanism could behind the association between high plasmaof RBP4 level and type 2 DM.
Ergonomic Redesign of Computer Laboratory to Improve Electric Power Performance and Working Efficiency Wijaya, I Ketut; Adi Putra, I Nyoman; Sutajaya, I Made; Sari Hartati, Rukmi
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.679 KB)

Abstract

The current problems in the Computer Laboratory of Udayana UniversityTechnical Engineering Faculty include non-standard room temperature of 28 0 C, nonstandardlight intensity average in the room of 110 lux, seat height of 43 cm and tableheight of 74,50 cm being not adapted to the workers’ anthropometric measurements, anddazzling white-colored curtains. Baseline data on six students after 3-hour workingrevealed the following findings: eye fatigue 81%’ and general fatigue 88%;musculoskeletal complaints 51%; average learning achievement 59.5%, performance16.25%, and efficiency 10.09%. In an effort to improve the working conditions, a totalexperimental ergonomic intervention in the form of redesigning the Computer Laboratorywas introduced.In this study 30 subjects were recruited. The data collected were analyzed by usingdesriptive statistics, normality test, comparability test, and paired-simple t-test with asignificant level of 5%.Total ergonomic intervention has resulted in a decrease of room temperature from280 C to 25.830 C (p<0.05), increase in light intensity from 110 lux to 136.67 lux, decreasein eye fatigue from 81% to 23% (p<0.05), decrease in general fatique 88% to 41%,decrease in musculoskeletal complaints from 51% to 11% (p<0.05), increase in learningachievement score from 59.5% to 89.5% (p<0.05), increase in performance from 16.25%to 41.25%, and increase in efficiency from 10.09% to 75.09% (p<.05).The results of this study revealed that appropriate total ergonomic intervention in acomputer laboratory had succeeded in improving the quality of working and performanceof the workers.
STEROID FOR MANAGEMENT OF PSEUDO-OTHEMATOMA Sudana, Wayan; Adiputra, Nyoman; Wiyadi, H.M.S.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (83.538 KB)

Abstract

Has conducted research on the use of steroids triamsinolon asetonid as pseudo-othematomamedical therapy. The purpose of this study was to determine the effectiveness triamsinolonasetonid. Prevention of the formation of serum in the lesion, so that pseudo-othematomacan be cured without surgery. Surgery and preventing of the formation collagen tissue inthe lesion, so that the pseudo-othematoma can be cured without deformity. It is expectedthe establishment of a pseudo-othematoma practical for health personnel, effective,efficient, safe and comfortable for the patient. This study design is the design of arandomized controled pretest-postest design. In the test group were treated withtriamsinolon asetonid intracutaneus injected in lesion area with the number according tothe percentage of the amount of teraphy effusion before. Then press verban installed. In thecontrol group, only pressing verban installed. From the research results obtained, whishafter the third treatment using the triamsinolon asetonid, pseudo-othematoma diseaselooked very meaningful. Due to its unique histological structure of the ear, then themanipulation of the ear is moe advisable to be careful, to prevent new lession with variousimpacts.
“TEMPE” REDUCES DNA DAMAGE IN RATS IRRADIATED WITH ULTRAVIOLET RAY Maryam, Siti; Sudewa Djelantik, A. A. Gde; Agus Bagiada, I Nyoman; Mantik Astawa, Nyoman
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (139.106 KB)

Abstract

‘Tempe’ is a popular Javanese-Indonesian tradisional food made of fermentedsoyabean. This study aims to examine whether ‘tempe’, used as a strong anti-free,has the ability to decrease DNA damage induced by ultraviolet ray irirradiation inthe Wistar rats as indicated by the levels of urinary 8-hydroxy-2-deoxyguanosine.A Total of 24 Wistar rats, 2.5 to 3 mounths and 200 gr body weight, weredividing into 4 groups of equal size i.e. three treatment and one control groups.All rats were exposed to 5-hours daily UV ray sources of UV 15 watt Philip for 60days. Randomized post test only control group design was used in this study withindependent variables of 0, 1, 2 and 3 g ‘tempe’ per kilogram body weight per dayand independent variables of 8-hydroxy-2-deoxyguanosine urinary level as aDNA damage biomarker following an oxidative stress. Data were analyzed byusing one way ANOVA followed by Tukey HSD.The results of our study indicates that there is a decrease of DNA damageis manifested by progressive decrease of 8-hydroxy-2-deoxyguanosine level in thetreatment groups as compared to the control group. Statistically significantdecrease of 22.61 % and 25.62 % was shown with p > 0.05.From our analysed data is could be inferred that ‘tempe’ has the ability todecrease DNA damage caused by ultraviolet ray irradiation. Supplementation of2 g ‘tempe’ per kilogram body weight per day appeared to have the strongesteffect of decreasing DNA damage in Wistar rats.

Page 1 of 1 | Total Record : 6

 1 

Filter by Year

2011 2011


Reset
Filter By Issues
All Issue Vol 8 No 1 (2014): IJBS Vol8 No1 Vol 7 No 1 (2013): IJBS Vol.7 No.1 January-June 2013 Vol 7 No 2 (2013): IJBS Vol2 No2 Vol 6 No 2 (2012): Indonesian Journal of Biomedical Sciences Vol. 6, No. 1 Januari 2012 Vol. 5, No. 2 Mei 2011 Vol. 5, No. 1 Januari 2011 Vol. 4, No. 2 Juli 2010 Vol. 4, No. 1 Januari 2010 Vol. 3, No. 2 Juli 2009 Vol. 3, No. 1 Januari 2009 Vol. 2, No. 2 Mei 2008 Vol. 2, No. 1 Maret 2008 Vol. 1, No. 3 Desember 2007 More Issue