Article Per Year (5 Year)
p-Index From 2021 - 2026
3.612
P-Index
This Author published in this journals
All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence Open Access DRIVERset African Journal of Biochemistry and Molecular Biology Research Open Access DRIVERset African Journal of Sciences and Traditional Medicine Open Access DRIVERset Kwaghe International Journal of Arts, Humanities and Religious Studies African Journal of Clinical Medicine and Pharmacy Research African Journal of Medicine, Surgery and Public Health Research
Akafa, Tensaba Andes
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 28 Documents
Search

 1   2   3 
Influence of Emotional Intelligence on the Mental Health of the Federal Road Safety Corps Personnel in Benue State Sector Command Zakariah, Danladi; Ihaji, Elvis O.; Akafa, Tensaba Andes; Akafa, Vika Tensaba; Iseko, Kingsley Iyoko; Oladele, Gloria Omonefe
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.3977

Abstract

This study examined Emotional Intelligence on the Mental Health of the Federal Road Safety Corps Personnel in Benue State Sector Command. The study employed a cross-sectional survey design in which 232 Federal Road Safety Corps Personnel whose ages ranged from 20 – 58 years (Mean age=36.30, SD=8.34), comprising 169(72.8%) males and 63(27.2%) females who served as participants for the study. Emotional intelligence Scale and Mental Health Inventory scale were used in data collection. The result of the finding shows that, there was a significant positive influence of emotional intelligence on mental health of Federal Road Safety Corps Personnel in Benue State Sector Command [R=.436, R2=.190, F (5,227) =3.627, p<.01]. The result also indicated that, emotional intelligence and its dimensions explained 19.0% of the variance observed in mental health among the participants. This means that, Federal Road Safety Personnel with high levels of emotional intelligence are likely to have good mental health, and the extent to which emotional intelligence explains mental health of Federal Road Safety Corps Personnel in Benue State Sector Command is 19.0%, and based on this finding, the second hypothesis was confirmed. Independently, findings revealed that, social skills made the highest significant contribution (β=.299, t=2.988, p<.05), followed by motivation (β=.223, t=2.588, p<.05), and then self-reputation (β=.211, t=2.081, p<.05), followed by social awareness (β=.198, t=1.758, p<.05), and self-awareness (β=.180, t=1.313, p<.05) successively. Based on this finding, it was recommended that the management of Federal Road Safety Corps in Benue State Sector should explore ways of improving the personnel's emotional intelligence deficit which may enhance succees and improve their mental health.
The Effect of Aqueous Solution of Hibiscus sabdariffa (Zobo Drink) on Albino Wistar Rats Ovarian Tissue Akafa, Tensaba Andes; Ujah, Williams Oche; Eli, Isaac Kogi; Ayara, Charles; Makanjuola, Victor; Williams, Queen Uyo; Istifanus, Dafup Katdel; Akafa, Vika Tensaba; David, Izam Emmanuel; Iseko, Kingsley Iyoko; Akafa, Ranyang R.
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.4011

Abstract

Hibiscus sabdarrifa is a flowering plant that grows in tropical regions. It is used in the preparation of a non-alcoholic beverage called Zobo drink. This current study investigated the ovarian histological changes and hormonal level outcome that occur after administration of Hibiscus sabdarrifa aqueous solution (Zobo drink) on albino Wistar rat. Twenty (20) female Wistar rats were purchased and divided into five (5) groups, group A, group B, group C, group D and group E with each group having four (4) Wistar rats. Group A, the control group was unexposed to any form of foreign substance. Group B were given 0.5ml of Zobo drink once daily (morning). Group C were given 0.5ml of Zobo drink twice daily (morning and afternoon). Group D were given 0.5ml of Zobo drink three times daily (morning, afternoon and evening). Group E were given the Zobo drink concurrently all through the day and water only at night. In the end, the rats were sacrificed and the ovaries were removed and fixed in 10% formalin saline solution. The ovaries were stained with hematoxylin and eosin. Their blood was collected through the femoral artery for hormonal level assay. The histological result of group A, B, C and D showed normal histological structures. Group E showed hemorrhage in the corpus luteum of the ovaries. The result of the hormonal analysis showed an increase in the level of progesterone, follicle stimulating hormone and luteinizing hormone and decrease in the level of estrogen all through the five groups. This lower estrogen level could impede menstruation. Therefore, Zobo drink can damage the ovary if taken in excess quantity and cause fluctuation in hormonal level of the ovary.
Psychoeducation of the Nigeria Population on Knowledge of Substance Abuse, Drug Addiction and Regular Medical Check-Up Zakariah, Danladi; Akafa, Tensaba Andes; Akafa, Vika Tensaba; Oladele, Gloria Omonefe; Iseko, Kingsley Iyoko; David, Izam Emmanuel; Ujah, Oche Williams; Gadin, Ndentang Ira
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.4078

Abstract

This paper aims to enhance psychoeducation among the Nigerian population regarding substance abuse, drug addiction, and the importance of regular medical check-ups. Substance abuse and drug addiction are significant contributors to various medical health conditions and mental disorders within the Nigerian populace. Many of these conditions could potentially be prevented or managed effectively if early detection of abnormal neurotransmitter changes in the brain was facilitated through routine medical examinations. This study highlights the alarming scarcity of knowledge and poor attitudes towards substance abuse, drug addiction, and regular medical check-ups in Nigeria, as evidenced by empirical data from psychiatric research. Such deficiencies hinder individuals from making informed health decisions and recognizing risk factors associated with unhealthy lifestyles. According to the World Health Organization, as well as the International Classification of Diseases (ICD-11) and the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), substance abuse and drug addiction are classified as diseases that require treatment, akin to conditions such as diabetes, cancer, heart disease, and HIV. In light of this, the paper calls on the government, as well as the management of healthcare institutions, clinical psychologists, and other healthcare professionals, to prioritize intensive psychoeducation initiatives. These initiatives should focus on raising awareness about the dangers of substance abuse and drug addiction, as well as preventative measures. Moreover, the government and health institutions should collaborate with philanthropists to establish more psychiatric hospitals and rehabilitation centre, providing testing equipment and medications at subsidized rates across all healthcare levels. This would enable individuals struggling with substance abuse and addiction to access necessary services, gain insights into their health status, improve their overall well-being, and alleviate the catastrophe financial burdens faced by their families and loved ones. In conclusion, this paper emphasizes the urgency of addressing these issues and provides actionable recommendations for creating a more informed and supportive environment for those affected by substance abuse and addiction.
Assessment of Anti-Hepatitis B Virus Activity of Leaf Extract of Morinda Citrifolia Umaru, Isaac John; Yuguda, Ismail Yunusa; Ngbede, Ocheifa Mathew; Iseko, Kingsley Iyoko; Abdulrasheed, Lubabatu; Akafa, Tensaba Andes; Okwori, Ameh Godwin
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4593

Abstract

Hepatitis B virus infection remains a global health problem, it is a leading cause of liver disease and a possible worldwide source of severe morbidity and mortality. The current standard therapy using interferons or antiviral agents is not successful in all cases and is associated with severe side effects. Consequently, the development of new medicines for the treatment of HBV is still relevant. This experimental study was therefore performed to assess the anti-hepatitis B virus (HBV) potential of Leaf extract of Morinda citrifolia. The methanolic extracts of the Leaf extract of Morinda citrifolia first assessed for cytotoxicity on HepG2.2.15 cells and cytotoxicity concentration (CC50) values were resolved. The methanolic extracts of the Leaf extract of Morinda citrifolia was additionally examined on HepG2.2.15 cells for anti-HBV potential by examining the inhibition of HBsAg and HBeAg production in the culture supernatants, and calculating their half-maximum inhibitory concentration (IC50) and therapeutic index (TI) values. Out of four concentration only three exhibit inhibition of HBsAg production in an increasing dose and time dependent manner. These four concentrations are 100 μg/mL, 200 μg/mL, 300 μg/mL and 400 μg/mL, with IC50 values of 21.15, 24.51, 118.94, 17.65, 20.93 μg/mL, respectively. Moreover, the presence of terpenoids, tannins, alkaloids and flavonoids that could contribute to antiviral efficacy was validated with a qualitative phytochemical study of active extracts.
Antihypertensive Effects of Ethanol Stem-Bark Extract of Morinda Citrifolia in Rats Umaru, Isaac John; Okwori, Ameh Godwin; Ngbede, Ocheifa Mathew; Abdulrasheed, Lubabatu; Iseko, Kingsley Iyoko; Akafa, Tensaba Andes
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4594

Abstract

The medical term used for blood pressure is Hypertension (HTN). Hypertension is a common problem faced by most people today. The leading danger for many diseases such as CVD (cardiovascular) disorder and stroke is high blood pressure. Major diseases like CHF (congestive heart failure), renal disease and blindness can also be caused by HTN. Awareness of plant-based medication therapeutics is continuously increasing day by day. Morinda citrifolia L (Noni) has been used in folk remedies by Polynesians for over 2000 years, and is reported to have a broad range of therapeutic effects. The purpose of this study is to investigate the hypotensive potential of Morinda citrifolia L (Noni) (Family: Rubiaceae) in both normotensive and hypertensive rats. Methods: Aqueous-methanol (70:30) extract of Morinda citrifolia L stem-bark extract at doses of 25, 50, 75 and 100 mg/kg was evaluated for its effect on blood pressure and heart rate using non-invasive blood pressure measuring apparatus. After initial screening, 100 mg/kg dose that produced a maximum effect was selected for the antihypertensive study. Median lethal dose (LD50) and sub-chronic toxicity of the extract were also determined. Various biochemical parameters and organ weight were measured using standard procedures. Results: The extract produced a significant (p < 0.01) decrease in systolic blood pressure (SBP), mean blood pressure (MBP), diastolic blood pressure (DBP) and heart rate of normotensive rats at all test doses with maximum effect at 100 mg/kg. Similarly, a significant antihypertensive and negative chronotropic effect was observed in both hypertensive models. LD50 of the extract was 200 mg/kg in mice. The extract also exhibited a reduction (p < 0.05) in serum alanine transaminase (ALT), aspartate aminotransaminase (AST), alkaline phosphatase (ALP), triglycerides and low-density lipoprotein (LDL) levels while a significant (p < 0.05) increase in high density lipoproteins (HDL) level was observed. Conclusion: It seems that the aqueous-methanol stem-bark extract of Morinda citrifolia L possesses active compounds which may be responsible for the antihypertensive and negative chronotropic effects in rats.
Unpacking the Pain: Understanding Barriers and Unmet Needs of Adults with Low Back Pain in a Southern Nigeria Outpatient Clinic Muoghallu, Obianuju Iheomamere; Mark, Akaninyene; Akafa, Tensaba Andes; Oladele, Gloria Omonefe; Iseko, Kingsley Iyoko
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4610

Abstract

Background: Low back pain (LBP) is a prevalent health issue leading to functional disability in adults. This study aimed to evaluate the barriers to care and unmet needs of adults with LBP and functional disability attending the General Out-Patient Clinic (GOPC) at the University of Uyo Teaching Hospital, Akwa Ibom State. The goal is to enhance quality of life by reducing disability and LBP burden through prevention, addressing barriers, and fulfilling unmet needs. Key barriers identified include limited access to healthcare, high out-of-pocket costs, inadequate insurance coverage, and a lack of understanding of LBP and self-management strategies. Methodology: Conducted at the GOPC, this cross-sectional analytical study involved 370 adult patients (18+ years) using systematic sampling. Data collection spanned two months, employing an interviewer-administered semi-structured Oswestry lumbar disability questionnaire. Analysis utilized IBM SPSS version 27, with frequency tables for pain patterns and chi-square tests to assess associations between body mass index (BMI) and LBP severity. Results: The mean age of respondents was 40.2 years. LBP was significantly linked to low function, with the association strengthening over time. Most respondents were classified as obese (BMI 25.0-29.9 kg/m²), and 56.7% reported high pain intensity. Activities like lifting weights and sitting exacerbated pain for 70.3% and 66.2% of respondents, respectively. The median pain score was 52, with significant differences noted (p<0.001). Alcohol consumption was reported by 39.6% (p=0.005), while 72.2% did not smoke. Respondents with LBP were 1.70 times more likely to experience functional disability compared to those without. Conclusion: LBP is strongly associated with functional disability among adults. Unmet needs include limited rehabilitation access, inadequate education on LBP, and insufficient support for self-management. Addressing risk factors, implementing multi-modal pain management strategies, and enhancing health education are essential for preventing functional disability.
Assessment of HIV 1 GP120/CD4 Binding Inhibition Potential of Methanolic Extracts of Achyranthes Aspera Leaves Umaru, Isaac John; Akafa, Tensaba Andes; Akem, Ingwu Joseph; Ngbede, Ocheifa Mathew; Oteng, Joseph; Utioukpan, Ashaka Fidelis; Mijinyawa, Aboki Nwunuji; Akam, Odok Endurance; Ekup, Ogholo Ogholo
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5184

Abstract

Achyranthes aspera (Amaranthaceae) is an important medicinal herb found as a weed throughout Nigeria. Though almost all of its parts are used in traditional systems of medicines, leaves, seeds, roots and shoots are the most important parts which are used medicinally. The present article gives an account of updated information on its phytochemical and pharmacological properties. The Human immunodeficiency virus (HIV) infection is still contributing significantly in morbidities and mortalities in the world today. The drugs normally used to treat the infection are costly, toxic, and less effective due to resistance by HIV. Thus, the assessment of gp120-CD4 binding inhibition potential of Achyranthes aspera leaves extract was conducted using gp120-CD4 capture ELISA kits. Aqueous, methanol, and petroleum ether extracts were prepared at 1000, 500 and 250 μg/ml and tested for gp120-CD4 binding inhibition. Sub-cute toxicity assay was done using albino rats; Biochemical parameters including alanine amino transferase (ALT), aspartate amino transferase (AST) and alkaline phosphatase (ALP) as well as bilirubin for liver and urea, electrolytes and creatinine for kidney functions were evaluated. The results of the effect of crude aqueous, methanol and petroleum ether Achyranthes aspera leaves extract against gp120-CD4 showed inhibition ranging from 1.4 – 17.2 %. with 1000 μg/ml showing highest percentage of inhibition. There was no significant difference (P = 0.862) in terms of percentage inhibition between the three concentrations tested. Methanol extract demonstrated the highest percentage inhibition of gp120-CD4 bindings (17.2 %). No significant difference (P = 0.124) between the three extracts against gp-120-CD4 bindings was observed. The results of the sub-acute toxicity study have shown that, there were no physical changes in animals treated with 500 mg/kg of all the extracts. The result of liver function test revealed that, ALT, AST and ALP were within the normal range (12U/L) for both the high and low concentrations of the extracts including the control. Also result for total protein, albumin, globulin for the test albino rats and that of the control rat were found to be within the normal range 5.1-6.1, 4.2-5.3, and 3.1-3.8 g/dl respectively. For serum electrolyte level, sodium and potassium ions for the various concentrations of the extracts tested and control were also found to be within normal range. The result of kidney function test revealed that, urea, creatinine and direct and total bilirubin of the rats tested and control were all found to be within normal range. In conclusion, ether Achyranthes aspera leaves extract possessed some levels of HIV-1 gp120-CD4 binding inhibition potentials and the extracts was found to be non-toxic at 250 and 500mg/ kg body weight. It can be recommended that, the bioactive compounds should therefore be isolated and tested for gp120-CD4 binding inhibition activity.
Persistent Threat of Lassa Fever in Nigeria: Epidemiology, Challenges, and Strategies for Effective Management Akafa, Tensaba Andes; John, Artu Ishishen; Oladele, Gloria Omonefe; Umaru, Isaac John
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5517

Abstract

Lassa fever is a viral hemorrhagic disease that poses a significant public health threat in Nigeria and West Africa. This review assesses the epidemiological trends, health impacts, and socioeconomic consequences of Lassa fever in Nigeria while proposing strategies for effective management and prevention. The natural reservoir of the Lassa virus, the multimammate rat (Mastomys natalensis), is prevalent in Nigerian households, facilitating transmission through direct contact with the rodents or their excreta, which often contaminates food. Consumption of these rats as a delicacy further exacerbates the risk. Current epidemiological data reveal that Lassa fever is endemic in Nigeria, with seasonal outbreaks primarily occurring in the dry season. The Nigeria Centre for Disease Control and Prevention (NCDC) reported 80 deaths and 413 confirmed cases across 11 states during Epidemiological Week 6 of 2025, with Taraba, Ondo, Bauchi, and Edo states accounting for over 73% of these cases. The Case Fatality Rate (CFR) for Lassa fever has risen to 19.4% in 2025, compared to 17.5% in 2024, likely due to factors such as underreporting and limited healthcare access. Notably, the CFR can range from 1% to 50%, influenced by healthcare access and early detection. The urgent nature of Lassa fever necessitates enhanced public health interventions, community education, and effective surveillance systems to mitigate its incidence and socioeconomic impact in Nigeria, thereby contributing to the achievement of Sustainable Development Goal target 3.3 to eliminate epidemics of Lassa fever and other neglected tropical diseases by 2030.
Co-Authors Abdulrasheed, Lubabatu Acha, Ozzioma Praise Agaba, Eric Agim Akafa, Ranyang R. Akafa, Vika Tensaba Akam, Odok Endurance Akem, Ingwu Joseph Akem3, Ingwu Joseph Ametsi, Smile Kobina Asare, Solomon Ossom Ayara, Charles Bafai, Favour Joel David, Izam Emmanuel Dennis, Adobeni Emmanuel Ekup, Ogholo Ogholo Eli, Isaac Kogi Enang, Kingsley Bassey Gadin, Ndentang Ira Gyasi, Prince Kwadwo Habibu, Bilyaminu Hassan, Okrah George Ihaji, Elvis O. Iseko, Kingsley Iyoko Istifanus, Dafup Katdel John, Artu Ishishen John, Tongle Nanle Kingsly, Iseko Iyoko Konka, Daniel Makanjuola, Victor Malantso, Jackson Soyinka Mark, Akaninyene Mijinyawa, Aboki Nwunuji Muoghallu, Obianuju Iheomamere Nanmar, Chakfa Ngbede, Ocheifa Mathew Ngbede, Ocheifa Matthew Ogochukwu, Edom Favour Okwori, Ameh Godwin Oladele, Gloria Omonefe Oteng, Joseph Tahidu, Issifu Tyem, Lawal Danjuma Udoh, Mary Athanasius Uduak, Peter Ise Ujah, Oche Williams Ujah, Williams Oche Umaru, Isaac John Umaru, Kerenhappuch Isaac Utioukpan, Ashaka Fidelis Williams, Queen Uyo Yuguda, Ismail Yunusa Zakariah, Danladi