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Review Artikel: Pengaruh Variasi Bahan Aktif terhadap Nilai SPF pada Sediaan Sunscreen Najma Kamila Zahra; Rosalba Sirly Najia; Cindy Fitria Dwi Nova; Yomanda Yomanda; Camelia Azka
Journal of Educational Innovation and Public Health Vol. 4 No. 2 (2026): April: Journal of Educational Innovation and Public Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/innovation.v4i2.9120

Abstract

Indonesia, as a tropical country, is exposed to high levels of ultraviolet (UV) radiation, increasing the risk of skin damage. Sunscreen is widely used as a protective measure indicated by the Sun Protection Factor (SPF) value. This study aimed to evaluate the effect of active ingredient variations on SPF values and other influencing factors. A literature review with a descriptive-comparative approach was conducted using research articles published between 2021 and 2026 from Google Scholar, PubMed, ScienceDirect, and Elsevier. A total of seven eligible articles were analyzed. The results showed that the type of active ingredients, concentration, combination of ingredients, and dosage form significantly influence SPF values. Natural ingredients generally produce low to moderate SPF values, while combinations of active ingredients result in significantly higher SPF due to synergistic effects. Increasing the concentration of active ingredients also leads to higher SPF values. Additionally, dosage forms such as creams, serums, sunscreen powder and foundations affect sunscreen effectiveness through their film-forming ability on the skin. In conclusion, the combination of active ingredients and higher concentrations provides more optimal protection against UV radiation.
Review Artikel: Pengaruh Jenis Eksipien terhadap Disolusi Tablet Najma Kamila Zahra; Intan Nova Kaesa; Elina Jatindria; Stella Reflya Pramudita; Dzikrina Adibah Salma
Journal of Educational Innovation and Public Health Vol. 4 No. 3 (2026): Juli: Journal of Educational Innovation and Public Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/innovation.v4i3.9261

Abstract

This study aimed to analyze the effect of excipient variations on tablet dissolution profiles and the underlying mechanisms. The research method used was a literature review by examining scientific articles published between 2021 and 2026. Literature sources were obtained from Google Scholar, ResearchGate, and relevant national and international journals. The analysis was conducted descriptively and comparatively on the use of excipients such as binders, disintegrants, lubricants, and surfactants in tablet formulations and their effects on dissolution parameters. The review results showed that the type of excipient significantly affects the dissolution profile of tablets. Binders can improve the mechanical strength of tablets but may slow down dissolution, while disintegrants accelerate tablet disintegration and increase the dissolution rate. Lubricants such as magnesium stearate may inhibit liquid penetration due to their hydrophobic properties, whereas surfactants can enhance drug solubility and accelerate the dissolution process. In addition, the concentration and combination of excipients also influence porosity, tablet hardness, wettability, and drug release mechanisms. Therefore, the selection and optimization of excipients are crucial in developing tablet formulations with optimal dissolution profiles and therapeutic effectiveness.