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Porous Calcium Carbonate-Poly-2-Acrylamido-2-Methylpropanesulfonic Acid Microspheres Embedded with Silver-Based Nanoparticles as Potential Antibacterial Carriers for Bone Infections Rini, Novi Dwi Widya; Asmoro, Adinda; Rachmawati, Systi Adi; Ardy, Husaini; Aimon, Akfiny Hasdi; Kishimura, Akihiro; Katayama, Yoshiki; wibowo, arie
Makara Journal of Science Vol. 29, No. 2
Publisher : UI Scholars Hub

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Abstract

Implant-associated infections (IAIs) are a significant complication following orthopedic surgeries and are mainly caused by Staphylococcus aureus. In this study, microspheres based on hybrid calcium carbonate–poly-2-acrylamido-2-methylpropane sulfonic acid (CaCO3-PAMPS) embedded with silver-based nanoparticles (AgNPs) were developed as potential antibacterial drug carriers for IAIs. AgNPs were prepared via a green synthesis approach, which employed Indonesian wild honey as a reducing and capping agent. PAMPS concentrations (0.025%, 0.050%, and 0.075% w/v) and silver ion (Ag+) concentrations in solution (0%, 2.5%, and 4% w/v) were varied. Scanning electron microscopy images showed that samples with 0.050% w/v PAMPS and 2.5% w/v Ag+ exhibited remarkable stability against recrystallization and aggregation. The sample exhibited more homogeneous, free-standing vaterite particles. Moreover, the particles obtained displayed a porous structure, promising for loading active ingredients. In addition, the X-ray diffraction results confirmed that the Ag-based particles embedded were not only AgNPs but were also predominantly composed of AgCl. AgNPs and AgCl in this sample demonstrated antibacterial activity against Staphylococcus aureus (zone of inhibition of 7.2 ± 0.6 mm). The development of stable, homogeneous microspheres with antibacterial properties and drug-loading potential offers a promising solution for the prevention and treatment of IAIs, addressing a critical challenge in orthopedic surgery.
Pengembangan Single-Page Simulation Visualisasi Komputasi Beban Terpusat pada Struktur Penyangga I-Beam Systi Adi Rachmawati; Sahid Triambudhi; Faisal Yusuf Fadhilah
Informatics and Digital Expert (INDEX) Vol. 8 No. 1 (2026): INDEX, Mei 2026
Publisher : LPPM Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/index.v8i1.2745

Abstract

Penelitian ini membahas pengembangan halaman interaktif sebagai alat bantu analisis awal untuk pemodelan pembebanan titik terpusat terhadap reaksi tumpuan sederhana pada struktur I-Beam. Permasalahan utama yang diangkat adalah proses analisis gaya reaksi yang sering kali masih dilakukan secara manual sehingga memakan waktu dan rentan akan kesalahan input. Metode penelitian yang digunakan meliputi formulasi matematis berbasis prinsip keseimbangan momen gaya yang diintegrasikan ke dalam pengembangan perangkat lunak berbasis web menggunakan teknologi HTML, CSS, dan JavaScript. Evaluasi kualitas perangkat lunak dilakukan melalui metode pengujian black box untuk memastikan seluruh fungsionalitas sistem berjalan sesuai rancangan tanpa kegagalan logika. Variasi beban diaplikasikan pada nilai 200 hingga 600 N pada batang sepanjang 5 meter. Hasil penelitian menunjukkan bahwa sistem mampu menghasilkan nilai gaya reaksi yang identik dengan perhitungan manual, sehingga terbukti akurat dan valid secara komputasi. Kontribusi utama penelitian ini dalam bidang informatika terletak pada implementasi algoritma komputasi numerik ke dalam lingkungan berbasis web, serta penyediaan model arsitektur sistem yang mampu mentransformasi perhitungan mekanika teknik yang kompleks menjadi perangkat lunak simulasi yang efisien dan presisi.
Enhancing Integrated Competencies in Vocational Students Through Mechanical and Software Engineering Collaboration in the Era of Industry 4.0 Stenli Octavian Eridheni; Januar Nur Rohmah Suprihartini; Systi Adi Rachmawati
Community Service Journal : Jurnal Pengabdian Masyarakat Mardira Vol. 1 No. 2 (2025): Community Service in Indonesia
Publisher : Politeknik Mardira Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71266/csj.v1i2.76

Abstract

The rapid development of digital technology in the era of Industry 4.0 demands multidisciplinary collaboration competence, especially between Mechanical Engineering and Software Engineering students in vocational education. However, the gap in digital literacy and automation skills among students still persists due to sectoral curricula, limited facilities, and minimal involvement of industry. This community service program aims to optimize interdisciplinary collaboration through technology-based knowledge transfer for vocational school students. The method consists of needs identification, coordination with partners, material preparation, training implementation, and evaluation. The activity was held at SMK PGRI Kandanghaur Indramayu, focusing on the introduction of programming, digital-based system modelling, and data presentation tools used in industrial environments. The results indicate increased students’ understanding of digital integration in mechanical systems and stronger motivation to pursue careers aligned with technological development. This initiative encourages the readiness of vocational education graduates to contribute to the transition toward Industry 4.0.
Analisis Performa Filtrasi Commercial PP-Melt-blown Electrospun Nanofiber Nylon-6 pada Udara Perkotaan Indonesia: Filtration Perfomance of Commercial PP Melt-blown Modified with Electrospun Nylon-6 Nanofiber for Indonesia Urban Air Januar Nur Rohmah Suprihartini; Stenli Oktavian Eridheni; Systi Adi Rachmawati
Jurnal Pendidikan Teknik Mesin Undiksha Vol. 14 No. 1 (2026)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jptm.v14i1.112577

Abstract

Masker N-95 yang selama ini menjadi andalan perlindungan pernapasan ternyata menyimpan keterbatasan. Lapisan serat-mikro polypropylene (PP) yang menjadi bahan utamanya dinilai belum cukup efektif dalam menangkap partikel-partikel berbahaya berukuran sangat kecil, sekaligus memiliki sifat mekanik yang masih perlu ditingkatkan. Berangkat dari tantangan tersebut, penelitian ini menghadirkan pendekatan inovatif dengan memodifikasi lapisan commercial PP melt-blown menggunakan nanofiber Nylon-6 yang difabrikasi melalui metode electrospinning. Membran non-woven yang dihasilkan kemudian dikarakterisasi secara menyeluruh mulai dari analisa sifat fisik hingga evaluasi kinerja filtrasi menggunakan Particulate Filtration Efficiency (PFE). Modifikasi PP melt-blown dengan nanofiber Nylon-6 terbukti mampu meningkatkan kinerja filtrasi secara signifikan, dengan nilai PFE terhadap PM0.3 yang berhasil melampaui angka 95%, didukung pula oleh nilai quality factor yang memuaskan. Capaian ini membuka harapan baru bahwa material komposit tersebut berpotensi menjadi solusi nyata dalam pengembangan masker N-95 yang lebih andal dan efektif untuk melindungi kesehatan masyarakat. The N95 mask, long regarded as a reliable frontline of respiratory protection, turns out to carry its own limitations. The microporous polypropylene (PP) fiber layer that forms its core material has been considered insufficiently effective at capturing extremely small hazardous particles and exhibits mechanical properties that still leave room for improvement. To address this challenge, the present study introduces an innovative approach by modifying a commercial PP melt-blown layer with Nylon-6 nanofibers fabricated via electrospinning. The resulting non-woven membrane was then comprehensively characterized, ranging from physical property analysis to filtration performance evaluation using Particulate Filtration Efficiency (PFE). Modification of PP melt-blown with Nylon-6 nanofibers significantly enhanced filtration performance, with PFE values against PM0.3 exceeding 95%, further supported by a satisfactory quality factor. This achievement offers renewed hope that the composite material has strong potential as a viable solution for developing a more reliable and effective N95 mask to safeguard public health.