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All Journal Jurnal Inovasi Farmasi Indonesia Jumat Ekonomi: Jurnal Pengabdian Masyarakat
Mohammad Firdaus Alshol
Universitas Kadiri
Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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Edukasi Penggunaan Obat Vitamin D (Kalsiferol) untuk Menjaga Kesehatan Tulang dan Gigi pada Remaja disertai Literasi Biaya Kesehatan di Kecamatan Pogalan Fendy Prasetyawan; Yuneka Saristiana; Mohammad Firdaus Alshol; Herman Herman; Novyananda Salmasfattah; Lisa Savitri
Jumat Ekonomi: Jurnal Pengabdian Masyarakat Vol. 7 No. 1 (2026): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas KH. A. Wahab Hasbullah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32764/abdimasekon.v7i1.7191

Abstract

Bone and dental health in adolescents are strongly influenced by adequate vitamin D intake; however, knowledge regarding its proper use remains limited, particularly in semi-urban areas. This community service activity aimed to improve adolescents’ understanding of rational vitamin D (calciferol) use accompanied by basic health-cost literacy education. The program was conducted on March 17, 2026, in Pogalan District and involved 12 adolescents. The study used a pre-experimental design with a one-group pretest–posttest approach. The intervention was carried out through interactive education covering the clinical aspects of vitamin D, rational drug use, and a simple introduction to preventive and curative costs related to vitamin D deficiency. Data analysis was performed using a paired sample t-test to compare knowledge scores before and after the intervention. The results showed a significant increase in knowledge scores after the intervention (p < 0.05), indicated by a shift in knowledge levels from low and moderate categories to predominantly high categories. These findings indicate that the integration of health education with health-cost literacy can support the improvement of adolescents’ understanding regarding the rational use of vitamin D. In conclusion, the educational intervention was effective in improving adolescents’ knowledge regarding the rational use of vitamin D.
Studi In Silico Senyawa Daun Sambung Nyawa (Gynura procumbens (Lour.) Merr.) terhadap HER2 dan EGFR sebagai Antikanker Payudara: In Silico Study of (Gynura procumbens (Lour.) Merr.) Compounds Against HER2 and EGFR as Breast Anticancer Mohammad Firdaus Alshol; Datin An Nisa Sukmawati; Novyananda Salmasfattah; Fendy Prasetyawan; Anis Akhwan Dhafin
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 7 No. 2 (2026): Volume 7 Nomor 2, Juni 2026
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v7i2.7723

Abstract

Kanker payudara adalah neoplasma ganas dengan karakteristik biologis yang beragam sehingga mmerlukan terapi spesifik. Pendekatan komputasi, seperti penambatan molekuler, simulasi dinamika molekuler, dan prediksi ADMET, banyak digunakan untuk mengidentifikasi kandidat obat antikanker secara efisien. Studi ini bertujuan untuk menghasilkan senyawa bioaktif potensial dari Daun Sambung Nyawa (Gynura procumbens (Lour.) Merr.) terhadap protein target HER2 dan EGFR sebagai kandidat obat kanker payudara. Penambatan molekuler dilakukan menggunakan AutoDock 4.0. Senyawa dengan energi terendah kemudian dianalisis melalui simulasi dinamika molekuler menggunakan YASARA dan sifat farmakokinetik dan toksisitasnya diprediksi berdasarkan parameter ADMET. Hasil menunjukkan bahwa beberapa senyawa memiliki afinitas pengikatan yang baik terhadap HER2 dan EGFR dan membentuk kompleks yang stabil berdasarkan nilai RMSD dan RMSF. Prediksi ADMET menunjukkan profil yang mendukung pengembangan lebih lanjut sebagai kandidat obat kanker payudara oral.
Co-Authors Anis Akhwan Dhafin Datin An Nisa Sukmawati Fendy Prasetyawan Herman Herman Lisa Savitri Novyananda Salmasfattah Yuneka Saristiana