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All Journal Jurnal Kesehatan, Rekam Medis dan Farmasi (JUK-Medifa) Ganec Swara
Nuradnin Hasan
Akademi Farmasi Kusuma Husada Purwokerto
Medicine & Pharmacology Nursing Public Health

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A Study on the Anatomy and Antibacterial Activity of Boesenbergia rotunda Rhizomes Against Staphylococcus aureus Siti Mutripah; Lailatul Badriyah; Muhammad Haykal Putra; Nuradnin Hasan; Sarwoko Sarwoko; Bambang Purwoko
Jurnal Kesehatan, Rekam Medis dan Farmasi (JUK-Medifa) Vol. 4 No. 01 (2026): JUK-Medifa (Jurnal Kesehatan, Rekam Medis dan Farmasi), 2026
Publisher : SEAN Institute

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Abstract

Boesenbergia rotunda is a plant belonging to the Zingiberaceae family. This plant is known to contain various bioactive compounds with potential as natural antibacterial agents. This study aims to determine the microscopic anatomical characteristics, secondary metabolite content, and antibacterial activity of Boesenbergia rotunda rhizome extract against Staphylococcus aureus. The research methods used included microscopic observation, phytochemical screening, and antibacterial activity testing using the disk diffusion method. Anatomical observations revealed that the Boesenbergia rotunda rhizome consists of parenchyma tissue with starch granules scattered throughout the ground tissue. Phytochemical screening results indicated the presence of flavonoids, alkaloids, terpenoids, saponins, and tannins. Antibacterial activity testing showed that the Boesenbergia rotunda rhizome extract was able to inhibit the growth of Staphylococcus aureus, producing an inhibition zone with a diameter of ±17 mm. This inhibition zone diameter falls into the category of strong inhibition. This strong antibacterial activity is believed to result from the synergistic action of secondary metabolites that work through mechanisms of cell membrane damage, disruption of membrane permeability, and inhibition of bacterial cell wall synthesis. Based on the research results, the rhizome of Boesenbergia rotunda has the potential to be developed as a natural antibacterial source derived from herbal materials.
PENGARUH PEMBERIAN PUPUK YANG BERBEDA PADA KULTUR SPIRULINA PLATENSIS DENGAN MEDIA AIR TAWAR SITI MUTRIPAH; LAILATUL BADRIYAH; SARWOKO SARWOKO; BAMBANG PURWOKO; NURADNIN HASAN
Ganec Swara Vol. 19 No. 1 (2025): Maret 2025
Publisher : Yayasan Al-Amin Qalbu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59896/gara.v19i1.229

Abstract

Indonesia is a vast maritime country with abundant aquatic biodiversity. One of the aquatic organisms that has not been optimally utilized is Spirulina platensis. Challenges in cultivation and high costs are among the reasons why Spirulina platensis is still rarely cultivated and utilized. In this experiment, a cultivation technique for Spirulina platensis was carried out using freshwater media with different fertilization treatments. The results of the experiment concluded that Spirulina platensis can grow well in freshwater media with the addition of Walne fertilizer, AB Mix, and POC. Fertilization with AB Mix resulted in the highest cell density growth on the fifth day of treatment, reaching 92,900 units/mL with a biomass of 103 mg/L. These results were higher compared to Walne fertilizer, which achieved 56,680 units/mL with a biomass of 74 mg/L, and POC fertilizer, which reached 43,800 units/mL with a biomass of 57 mg/L
Co-Authors Bambang Purwoko Lailatul Badriyah Muhammad Haykal Putra Sarwoko Sarwoko Siti Mutripah