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All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Pharmacon: Jurnal Farmasi Indonesia
Naura Nurnahari
Institut Teknologi Sumatera
Agriculture, Biological Sciences & Forestry Arts Humanities Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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DEMONSTRASI PEMBUATAN JAMU PENAMBAH NAFSU MAKAN PADA ANAK SEKOLAH DASAR KELAS V DAN VI SDN GEDUNG HARAPAN, LAMPUNG SELATAN Syaadatun Nadiah; Refsya Azanti Putri; Dewi Damayanti Abdul Karim; Gayatri Simanullang; Mubarika Sekarsari Yusuf; Naura Nurnahari; Nisa Yulianti Suprahman
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 9, No 5 (2026): MARTABE : JURNAL PENGABDIAN MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v9i5.1987-1991

Abstract

Nafsu makan yang baik sangat penting bagi kesehatan anak usia sekolah dasar karena berpengaruh pada kecukupan gizi, pertumbuhan, dan kecerdasan. Namun, rendahnya nafsu makan masih menjadi masalah yang sering dijumpai dan berisiko menurunkan kualitas kesehatan anak. Untuk itu, kegiatan pengabdian kepada masyarakat di SDN Gedung Harapan, Lampung Selatan dilakukan dengan memperkenalkan jamu penambah nafsu makan berbahan alami, yaitu temulawak, lemon, meniran, sereh, dan madu. Kegiatan meliputi optimasi produk, penyusunan materi, serta demonstrasi interaktif bersama siswa kelas 5 dan 6. Hasil evaluasi melalui pre-test dan post-test menunjukkan adanya peningkatan signifikan pemahaman siswa mengenai manfaat jamu (p0,05), sehingga kegiatan ini efektif meningkatkan kesadaran dan keterampilan anak dalam memanfaatkan tanaman obat sebagai alternatif sehat dan aman untuk mendukung nafsu makan serta kesehatan mereka
Potensi Teh Herbal sebagai Penghambat α-Amilase dan α-Glukosidase dalam Pengelolaan Diabetes Melitus Tipe 2: Tinjauan Literatur Annisa Nofriani; Naura Nurnahari; Mubarika Sekarsari Yusuf
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 3 (2026): Mei : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i3.2284

Abstract

Type 2 diabetes mellitus is a metabolic disorder with a steadily increasing global prevalence. Regulating blood glucose levels, particularly postprandial glucose, represents a critical strategy for the prevention and management of this disease. The inhibition of $\alpha$-amylase and $\alpha$-glucosidase activities is well-documented to delay carbohydrate digestion and subsequent glucose absorption. In recent years, herbal teas have gained significant attention as natural sources of bioactive compounds with potential antidiabetic properties. This literature review aims to evaluate the potential of various herbal teas, derived from both Camellia sinensis and non-Camellia sinensis species, in inhibiting $\alpha$-amylase and $\alpha$-glucosidase activities, based on in vitro studies published between 2016 and 2026. Relevant literature was gathered through systematic searches across PubMed and Google Scholar databases and further screened according to predefined inclusion criteria. A total of 26 articles were analyzed to evaluate enzyme inhibitory activities, the responsible bioactive compounds, and their reported mechanisms of action. The findings indicate that white and green teas exhibit potent $\alpha$-glucosidase inhibitory activity, primarily attributed to their catechin content, such as epigallocatechin gallate (EGCG) and epicatechin gallate (ECG). Furthermore, black, oolong, and dark teas, along with various polyherbal formulations, also demonstrated significant enzyme inhibition. Generally, polyphenols and other phenolic compounds serve as the primary constituents contributing to this biological activity. These findings suggest that herbal teas have the potential to be developed as an adjuvant therapy in the management of type 2 diabetes mellitus, although further in vivo studies and clinical trials remain essential to confirm their efficacy and safety.
A Review of Methodological Standards and Current Practices in Hemolytic Toxicity Testing of Nanoparticle-Based Drug Delivery Systems Mubarika Sekarsari Yusuf; Naura Nurnahari
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 2 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i2.13229

Abstract

Hemolytic toxicity testing is a fundamental component of hemocompatibility assessment for nanoparticle-based drug delivery systems (N-DDSs), as erythrocyte integrity reflects blood safety prior to clinical application. Despite its critical role, experimental procedures vary across the literature. Essential methodological details are frequently omitted, hindering reproducibility and standardization. This variability urges the need for a consolidated reference that examines both current practices and established guidelines. This narrative review aims to provide a structured overview of hemolytic toxicity testing methodologies applied to N-DDSs, with particular emphasis on procedural parameters and their alignment with ASTM and ISO standards. Literature was identified through Google search and open access Scopus-Indexed journals primarily covering publications from 2025 and supplemented with earlier studies to provide historical context. Articles were selected based on relevance to seven methodological parameters which were erythrocyte source, methods of erythrocyte separation and purification, incubation conditions, positive and negative controls, measurement method. Analysis of 30 publications revealed human erythrocytes were the predominant model, with phosphate buffered saline and detergent-like substances were most commonly used negative and positive controls, respectively. Centrifugation controls were inconsistently reported, while incubation was typically run at 37oC, with varying durations depending on the nanoparticle system. Variability was also observed in approaches used to quantify free hemoglobin. Overall, while hemolytic toxicity studies continue to rely on ASTM and ISO guidelines, greater methodological details and standardization would enhance the reliability and reproducibility of hemocompatibility assessments in nanoparticle drug delivery research.
Co-Authors Annisa Nofriani Damayanti Abdul Karim, Dewi Gayatri Simanullang Mubarika Sekarsari Yusuf Nisa Yulianti Suprahman Refsya Azanti Putri Syaadatun Nadiah