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Evaluasi Penurunan Skala Nyeri pada Pasien Pasca Seksio Caesarea dengan Injeksi Ketorolac dengan NRS dan FPS : Evaluasi Penurunan Skala Nyeri pada Pasien Pasca Seksio Caesarea dengan Injeksi Ketorolac dengan NRS dan FPS Annis Rahmawaty; Gunawan Firmansyah; Rifda Naufa Lina
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.7033

Abstract

Caesarean section (SC) is a surgical procedure to address complications during childbirth, a complication that is often experienced by post-SC patients is pain. Adequate pain management is important to ensure optimal recovery of post-SC patients. This study aimed to evaluate the decrease in the pain scale of post-SC patients after the use of Ketorolac injection. This study uses an observational study design with a retrospective analytical approach. The study sample is the medical records of post-SC patients who received Ketorolac injection as an analgesia in the February-April 2023 period. The sampling technique used accidental sampling according to the criteria totaling 89 people. The data collected included the demographic characteristics of the patient, the pain scale using NRS, FPS before and after the use of Ketorolac injection. The results of the study showed the age characteristics of pregnant women who had the most SC at the age of 26-30 years. The use of Ketorolac injection lowered the pain scale of post-SC patients with moderate and mild pain levels as evidenced by 85.3% of respondents experiencing a decrease in pain. Pain reduction after ketorolac injection averaged 1-2 pain scales with a duration of 2-4 hours after administration. The NRS,FPS pain assessment method can be used effectively in measuring the decrease in the pain scale of post-SC patients. Adequate post-SC pain management using Ketorolac injection can be an option to improve the quality of care for post-SC patients
Hubungan Antara Obat Yang Digunakan Terhadap Kejadian Kausalitas Adverse Drug Reactions (ADRs) dengan Menggunakan Skala WHO UMC Pada Pasien Congestive Heart Failure Annis Rahmawaty; Rifda Naufa Lina; Gunawan Firmansyah
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.8015

Abstract

Patients with Congestive Heart Failure (CHF) are often prescribed combination therapy, which may lead to Adverse Drug Reactions (ADRs). ADRs assessment can be performed using the WHO-UMC scale by considering the clinical pharmacological aspects of the case history, as well as the quality of documentation and patient observation. This study aimed to determine the relationship between the number of drugs used and the causality of ADRs based on the WHO-UMC scale in patients with Congestive Heart Failure. Data were collected prospectively during June 2025 from 58 patients with a duration of CHF of more than one year at RSI Sunan Kudus. The sampling technique used was total sampling. Data were analyzed descriptively using an observational approach, while the correlation analysis was conducted using the Chi-square test and Fisher’s Exact Test. The results showed that the majority of patients were aged 45–59 years, accounting for 29 patients (50%). ADRs were more frequently observed in male patients, with 36 cases (62.1%), compared to female patients, with 22 cases (37.9%). there are 49 comorbid diseases in patients. The most frequently reported ADR was dizziness, occurring in 17 cases (24.6%), while the most common causality category based on the WHO-UMC scale was “possible,” found in 36 cases. Most patients received more than five medications, with 44 cases reported. In conclusion, there was a significant relationship between the number of medications used and the causality of ADRs based on the WHO-UMC scale in patients with Congestive Heart Failure. The greater the number of medications administered, the higher the risk of ADRs.
Peningkatan Pemahaman Santri dan Pengelola Pesantren dalam Mengolah dan Mengonsumsi Produk Serbuk Kelor-Jahe di Pondok Pesantren As-Salamah Betahwalang Kabupaten Demak Anggita Dipika Wulandari; Rifda Naufa Lina; Matheus Prayoga Claus; Rahmawati salsa dinurrosifa; Laelatul Husniyah; Rizki Annisa Ramadhani; Setya Wahono; Aldo Octavian Ramadhan Saputra
Cakrawala: Jurnal Pengabdian Masyarakat Global Vol. 5 No. 3 (2026): Agustus: Cakrawala: Jurnal Pengabdian Masyarakat Global
Publisher : Universitas 45 Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30640/cakrawala.v5i3.7865

Abstract

Islamic boarding schools are educational environments characterized by communal living, presenting unique challenges for health maintenance. Factors such as high-density living, shared habits, and limited understanding of nutrition and the use of herbal ingredients can impact efforts to maintain the health of the students. Moringa oleifera and Zingiber officinale are local ingredients with potential for use in food diversification and herbal beverages. This community service activity aimed to enhance the understanding and skills of the students and administrators at the As-Salamah Betahwalang Islamic Boarding School regarding the utilization of Moringa and ginger by processing them into instant powder products. The activity employed an educational and participatory approach, encompassing education on balanced nutrition and immunity, an introduction to the benefits of Moringa and ginger, plant cultivation practices, demonstrations and training on instant powder production and packaging, and evaluation via pre- and post-tests. Participants actively engaged in discussions, demonstrations, processing practices, and cultivation activities. A Moringa-ginger instant powder product was successfully produced through a process involving ingredient preparation, boiling Moringa, processing ginger, filtering, heating, adding sugar, stirring until powder formed, and packaging. The activity also established Moringa and ginger cultivation practices as a strategy to ensure a sustainable supply of raw materials. This program provided the partners with a foundation of knowledge and skills for utilizing local herbal ingredients to create practical products with the potential for independent and sustainable development.
Senyawa Metabolit Sekunder pada Daun Kelengkeng dan Daun Jeruk Limau yang Berkhasiat sebagai Obat Tradisional Rifda Naufa Lina; Anggita Dipika Wulandari; Laelatul Husniyah
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 3 (2025): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i3.8041

Abstract

Public interest in natural remedies has increased significantly in recent years, leading to a growing reliance on traditional medicinal plants as alternative or complementary therapies. Among the plants widely used across generations in various cultural practices are longan leaves (Euphoria longan (Lour.) Steud) and kaffir lime leaves (Citrus amblycarpa (Hassk.) Ochse). Both are believed to possess a variety of health-promoting properties and have long been utilized in traditional medicine for their therapeutic potential. Despite their popularity, scientific investigations that specifically explore their phytochemical composition and pharmacological activities remain limited. This study was therefore conducted to examine the secondary metabolite content of both plants and to evaluate their potential as sources of bioactive compounds. The extraction process was carried out using the maceration technique with 96% ethanol as a solvent, followed by a series of phytochemical screening tests. The analysis aimed to identify the presence of key classes of secondary metabolites such as flavonoids, alkaloids, tannins, saponins, terpenoids, and steroids, which are known to contribute to various biological activities including antioxidant, anti-inflammatory, antimicrobial, and hepatoprotective effects. The results revealed that both longan and kaffir lime leaves tested positive for all targeted secondary metabolite groups. The consistent presence of flavonoids, alkaloids, tannins, saponins, terpenoids, and steroids suggests that these plants hold considerable pharmacological promise. Their metabolite profiles align with the reported therapeutic uses of these leaves in traditional medicine, providing scientific support for their continued application as herbal remedies. Overall, this research strengthens the understanding of Euphoria longan and Citrus amblycarpa as potential sources of phytopharmaceuticals. The findings not only validate their traditional medicinal uses but also highlight their potential in the development of natural-based drug formulations. Further in-depth studies, including isolation of active compounds and pharmacological assays, are recommended to fully characterize their therapeutic properties and clinical applications.