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All Journal Indonesian Journal of Medicine Jurnal Pengabdian Pada Masyarakat METHABDI
Fauzi, Tengku Muhammad
LP3M UNIVERSITAS METHODIST INDONESIA
Religion Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health

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The Effects of Ethanol Extract, Chayote (Sechium Edule (Jacq.) Swartz) Fraction and Juice on the High-density Lipoprotein Level in Male White Mice Siahaan, Jekson Martiar; Anto, Endy Juli; Fauzi, Tengku Muhammad
Indonesian Journal of Medicine Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.583 KB)

Abstract

Background: Cholesterol imbalance occurs in Diabetes Mellitus, where high-density lipo­protein (HDL) levels are low and low-density lipoprotein (LDL) increases, where this im­balance results in the appearance of athero­sclerosis. HDL has antiarterosclerotic poten­tial so it needs to be targeted for therapy. One of the bioactive compounds that have this effect is found in chayote (Sechium edule (Jacq.) Swartz). This study aimed to examine the effects of ethanol extract, Chayote (Sechium Edule (Jacq.) Swartz) fraction and juice on the hdl level in male white miceSubjects and Method: A randomized controlled trial study was conducted to test HDL level in 54 male white rats of the Wistar strain (Rattus novergius sp.) after received ethanol extract, Chayote (Sechium Edule (Jacq.) Swartz) fraction and juice. The depen­dent variable was the HDL level. The indepen­dent variable was the variation in the dose of ethanol extract, fraction and Sechium edule (Jacq.) Swartz Juice. The data were analyzed using Anova test.Results: The treatment group induced by Streptozotocin 50 mg / kgBW + nicotinamide (120 mg/kgBW) + HFD and obtained ethanol extract of chayote fruit 150 mg / kgBW, orally had the highest average HDL levels compared to other groups (Mean = 17.31; SD = 3.14).Conclusion: The ethanol solvent found in the ethanol extract is better because it attracts biaoctive compounds so that it has a better effect than the ethyl acetate fraction and the n-hexane fraction.Conclusion: The ethanol solvent found in the ethanol extract is better because it attracts biaoctive compounds so that it has a better effect than the ethyl acetate fraction and the n-hexane fraction.Keywords: HDL, Flavonoid, Sechium edule (Jacq.) SwartzCorrespondence: Jekson Martiar Siahaan. Department of Physiology, Faculty of Medicine, Universitas Methodist Indonesia. Jl. Setia Budi Pasar II Tj. Sari, Medan 20132, North Sumatera. Email: jekson.siahaan.sked@gmail.comIndonesian Journal of Medicine (2021), 06(02): 145-151https://doi.org/10.26911/theijmed.2021.06.02.03
Penyuluhan Otitis Media Akut kepada Anak Panti Asuhan Advent Peduli Sembiring, Budi Darmanta; Anto, Endy Juli; Fauzi, Tengku Muhammad; Siahaan, Jekson Martiar; Tarigan, Menang Bastanta; Sijabat, Kesia; Sihaloho, Kerin Repaskatri; Manik, Widya Dayanti Feronika; Simanjuntak, Jeremia; Wijaya, Mega; Sihaloho, Lovian Nauli; Sembiring, Mikael; Panjaitan, Bintang Andika; Sitompul, Michael Sabatino; Momot, Estela Salomina
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 1 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No1.pp6-10

Abstract

In accordance with the application of the Tri Darma of Higher Education in the doctor's professional study program, one of which is community service. The purpose of community service activities is to provide explanations and education that can influence community behavior. This community service was carried out at an advent orphanage caring for children and adolescents with 25 participants. This community service activity was carried out on December 6, 2023, with the material of acute otitis media. This topic is very much needed in order to provide information and knowledge about acute Otitis media. Behavior to maintain ear hygiene and health to prevent this disease. Lack of knowledge many are subjected to unfavorable issues. Through this health counseling, it is expected that children and adolescents at Advent Peduli Orphanage, Gg. Kasih no 8, Sudirejo II, Kec. Medan Kota are always motivated to stay alert when playing with friends and keep their ears healthy.
Co-Authors Endy Juli Anto Manik, Widya Dayanti Feronika Momot, Estela Salomina Panjaitan, Bintang Andika Sembiring, Budi Darmanta Sembiring, Mikael Siahaan, Jekson Martiar Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sijabat, Kesia Simanjuntak, Jeremia Sitompul, Michael Sabatino Tarigan, Menang Bastanta Wijaya, Mega