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All Journal Meditory : The Journal of Medical Laboratory Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya
Danny Meganingdyah Primartati
Institut Ilmu Kesehatan Bhakti Wiyata Kediri
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health

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Potensi Hiperglikemia pada Warga Binaan Penyalahguna NAPZA: Deskripsi Gula Darah Puasa dan Karakteristik Metabolik Aulia Risqi Fatmariza; Danny Meganingdyah Primartati; Angga Eka Kurniawan; Rahmad Darmawan; Aprilia Kusumaningrum
Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Vol 7 No 1 (2026): Juni 2026
Publisher : Fakultas Sains, Teknologi, dan Analsisi Institut ilmu Kesehatan Bhakti Wiyata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56399/jst.v7i1.399

Abstract

Substance abuse can disrupt glucose metabolism and increase the risk of undetected hyperglycemia, particularly in vulnerable populations such as inmates. This study aimed to describe fasting blood glucose levels and metabolic characteristics among substance-abusing inmates. A descriptive cross-sectional study was conducted involving 80 inmates selected by total sampling. Data included fasting blood glucose, body mass index, and blood pressure. Descriptive statistical analysis was performed, including mean, median, standard deviation, range, and proportion of hyperglycemia. The mean fasting blood glucose level was 121.3 mg/dL (median 117 mg/dL; SD 22.77 mg/dL; range 84–204 mg/dL). Hyperglycemia was observed in 42.5% of respondents. A proportion of subjects were also classified as obese and hypertensive. Substance-abusing inmates demonstrate a considerable burden of hyperglycemia, highlighting the importance of routine metabolic screening in correctional settings. Keywords: fasting blood glucose; hyperglycemia; substance abuse; inmates; metabolic risk
ANALYSIS OF PLATELET-LYMPHOCYTE RATIO IN TYPE 2 DIABETES MELLITUS AS A SYSTEMIC INFLAMMATION BIOMARKER Fathul Hidayatul Hasanah; Sri Wahyuni; Danny Meganingdyah Primartati; Aulia Risqi Fatmariza; Fita Sari
Meditory : The Journal of Medical Laboratory Vol. 14 No. 1 (2026): Meditory, Volume 14 No. 1 Tahun 2026
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v14i1.4056

Abstract

Background: Chronic hyperglycemia in type 2 DM causes chronic low-grade systemic inflammation, which triggers complications. The body responds with an increase in proinflammatory cytokines and changes in blood cell hemostasis. The platelet lymphocyte ratio (PLR) is a new inflammatory marker that has clinical prognostic value. Objective: Comparison of PLR values in type 2 DM without complications with the cardiovascular and nephropathy complication groups. Methods: The study employed a retrospective research design and included a total of 617 respondents with type 2 DM. The respondents were divided into three groups: 162 with uncomplicated type 2 DM, 291 with cardiovascular complications, and 164 with nephropathy. The data was collected from Mojowarno Christian General Hospital in Jombang. Results: The mean value of PLR in uncomplicated type 2 DM was 238.4 ± 225, in cardiovascular 327.11 ± 162, and in nephropathy 449.52 ± 107. The difference test yielded a statistically significant result p < 0.001, indicating that there were notable differences in PLR values across the three type 2 DM groups. Conclusions: There is a difference in PLR values in type 2 DM between the group without complications and the group with complications (cardiovascular and nephropathy).
Co-Authors Angga Eka Kurniawan Aprilia Kusumaningrum Aulia Risqi Fatmariza Fathul Hidayatul Hasanah Rahmad Darmawan Sari, Fita Wahyuni, Sri