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All Journal Scientific Journal of Pediatrics Crown: Journal of Dentistry and Health Research
Aprilia Sari
Department of Oral Health and Dentistry, CMHC Research Center, Palembang, Indonesia
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Early Childhood Feeding Practices and the Development of Severe Early Childhood Caries (S-ECC): A Prospective Cohort Study in Medan, Indonesia Andhika Kurnianta Kusuma; Muhammad Ashraf; Yi-Fen Huang; Aprilia Sari; Firman Hadi; Sohyuk Kim
Scientific Journal of Pediatrics Vol. 3 No. 1 (2025): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v2i2.175

Abstract

Introduction: Severe early childhood caries (S-ECC) is a significant public health problem, particularly in developing countries like Indonesia. Early childhood feeding practices are recognized as major risk factors, but prospective data from specific regions like Medan, Indonesia, are limited. This study aimed to investigate the association between various feeding practices and the development of S-ECC in a cohort of children in Medan. Methods: A prospective cohort study was conducted involving 450 mother-child dyads recruited from Posyandu (integrated health posts) in Medan, Indonesia. Baseline data on maternal demographics, socioeconomic status, oral health knowledge, and infant feeding practices were collected via questionnaires and interviews. Children were followed up at 6-month intervals for 36 months. Dental examinations were performed by calibrated dentists using the dmft index (decayed, missing, filled teeth) to diagnose S-ECC. Cox proportional hazards regression was used to analyze the association between feeding practices and S-ECC development, adjusting for potential confounders. Results: The incidence of S-ECC at 36 months was 38.2% (n=172). Prolonged bottle feeding (beyond 12 months) (Hazard Ratio [HR] = 2.15; 95% Confidence Interval [CI]: 1.55-2.98; p<0.001), nocturnal bottle feeding with sweetened liquids (HR = 2.85; 95% CI: 2.01-4.03; p<0.001), and frequent consumption of sugary snacks/drinks (≥3 times/day) (HR = 1.92; 95% CI: 1.38-2.67; p<0.001) were significantly associated with an increased risk of S-ECC. Exclusive breastfeeding for the first 6 months showed a protective effect (HR = 0.62; 95% CI: 0.45-0.86; p=0.004), even after adjusting for socioeconomic status and maternal oral health knowledge. Conclusion: This study confirms the significant impact of early childhood feeding practices on S-ECC development in Medan, Indonesia. Prolonged and nocturnal bottle feeding, particularly with sweetened liquids, and frequent consumption of sugary snacks/drinks were key risk factors. Promoting exclusive breastfeeding for the first six months and educating mothers about appropriate feeding practices are crucial for S-ECC prevention in this population.
Clinical and Inflammatory Efficacy of a Novel Bioactive Borate Glass Air-Abrasion Powder for Peri-implant Mucositis Treatment: A Split-Mouth Randomized Controlled Clinical Trial Nur Diana; Indri Yani Septiana; Aprilia Sari; Michelle Birne
Crown: Journal of Dentistry and Health Research Vol. 3 No. 1 (2025): Crown: Journal of Dentistry and Health Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/crown.v3i1.235

Abstract

Introduction: Peri-implant mucositis (PIM) is a prevalent inflammatory condition requiring effective biofilm management. This study aimed to evaluate the clinical and inflammatory efficacy of a novel bioactive borate glass (BBG) air-abrasion powder compared to a standard glycine-based powder for treating PIM. Methods: This was a split-mouth randomized controlled trial conducted at Palembang, Indonesia. Forty-two patients with two implants each, both diagnosed with PIM (Bleeding on Probing [BOP] positive, Probing Pocket Depth [PPD] 4 mm), were enrolled. In each patient, one implant site was randomly assigned to receive sub- and supragingival air-abrasion with the BBG powder (Test Group), while the contralateral implant received treatment with glycine powder (Control Group). Clinical parameters, including Modified Plaque Index (mPI), Modified Gingival Index (mGI), PPD, and BOP, were recorded at baseline (T0), 4 weeks (T1), and 12 weeks (T2). Peri-implant sulcular fluid (PISF) was collected to quantify levels of Interleukin-1 Beta (IL-1β) and Tumor Necrosis Factor-Alpha (TNF-α). Patient-reported discomfort was assessed using a Visual Analog Scale (VAS). Results: Both groups showed significant improvements in all clinical parameters from T0 to T2 (p < 0.001). At the 12-week follow-up (T2), the Test group demonstrated a statistically significantly greater reduction in mean PPD (Test: 1.21 + 0.28 mm vs. Control: 0.83 + 0.31 mm; p < 0.001) and a higher percentage of BOP resolution (Test: 88.1% vs. Control: 66.7%; p = 0.012). Furthermore, the reduction in IL-1β and TNF-α concentrations from T0 to T2 was significantly greater in the BBG group (p < 0.01 for both). Both treatments were well-tolerated with low VAS scores. Conclusion: Within the limitations of this study, non-surgical treatment of peri-implant mucositis using the novel bioactive borate glass air-abrasion powder resulted in superior clinical and inflammatory outcomes compared to standard glycine powder. This bioactive approach presents a promising advancement in peri-implant maintenance therapy.
Intervention Effects on Post-Endodontic Pain in Trials Indexed Under Periodontitis: A ClinicalTrials.gov Aggregate-Data Analysis Annisa Annisa; Aprilia Sari; Kim Sohyuk
Crown: Journal of Dentistry and Health Research Vol. 3 No. 2 (2025): Crown: Journal of Dentistry and Health Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/crown.v3i2.331

Abstract

Background: Post-endodontic pain is a patient-important outcome, yet posted trial-registry results are difficult to compare because outcome scales, time points, and reporting structures vary. Objective: This study aimed to estimate the magnitude and precision of intervention effects on postoperative pain and to characterize their temporal and multiplicity-adjusted patterns in eligible randomized endodontic trials. Methods: ClinicalTrials.gov records from a frozen query for periodontitis studies with posted results were screened for randomized endodontic trials reporting arm-level pain means, dispersion, and denominators. Official API records were used to verify groups and outcomes. Raw mean differences and Hedges g with 95% confidence intervals were calculated without cross-trial pooling. Standard errors were converted to standard deviations where indicated, independent recruitment cohorts were combined within a trial, and multiplicity was controlled using Holm adjustment. Results: Among 64 records, 11 contained pain-related outcomes and 4 endodontic trials were eligible. The trials enrolled 257 participants; 249 contributed to pain denominators. Nine of 18 non-pooled confidence intervals excluded zero, while 7 comparisons from 2 trials remained significant after Holm adjustment. Photobiomodulation produced lower pain than sham at 0, 6, 12, 24, and 72 hours. Cryotherapy produced lower pain than saline at 24 and 48 hours after adjustment. Estimates for occlusal reduction, GentleWave versus EndoActivator, and ibuprofen/acetaminophen versus ibuprofen were not robustly different. Conclusion: Posted aggregate results revealed treatment- and time-specific signals rather than a common intervention effect. Verified extraction and multiplicity-aware non-pooled analysis improve interpretability, but clinical decisions require full publications and harmonized outcome definitions.
Co-Authors Andhika Kurnianta Kusuma Annisa Annisa Firman Hadi Indri Yani Septiana Kim Sohyuk Michelle Birne Muhammad Ashraf Nur Diana Sohyuk Kim Yi-Fen Huang