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All Journal Jurnal Surya Medika Jurnal Impresi Indonesia
Ahmad Ghiffari
Universitas Muhammadiyah Palangka Raya
Religion Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Animal Models for Studying Post-Stroke Neuroplasticity Risdiansyah Risdiansyah; Ahmad Ghiffari; Rury Tiara Oktariza; Fadhillah Putri Rusdi
Jurnal Impresi Indonesia Vol. 4 No. 5 (2025): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i5.6647

Abstract

Ischemic stroke remains one of the leading causes of long-term disability worldwide, with recovery dependent on the brain's neuroplastic potential. This review aims to evaluate the role of animal models in elucidating the mechanisms of neuroplasticity following stroke and their relevance to clinical application. Using qualitative literature analysis, the study synthesizes findings from various animal models including rodents, non-human primates, zebrafish, and Drosophila. Rodent models, particularly the middle cerebral artery occlusion (MCAO), have been instrumental in identifying key processes such as BDNF-driven synaptic remodeling, VEGF-induced angiogenesis, and glial involvement in tissue repair. Additionally, systemic modulators like the gut-brain axis, immune responses, and extracellular vesicles are increasingly recognized for their influence on recovery. Despite these insights, most studies disproportionately utilize young, healthy male animals, limiting their relevance to diverse patient populations with comorbidities and aging factors. The findings suggest a need for integrative, multimodal research that incorporates molecular techniques, imaging, and behavioral assays, along with cross-species validation, to improve translational outcomes. This review underscores the necessity of leveraging a broader spectrum of animal models and advanced methodologies to develop effective, personalized therapies for post-stroke rehabilitation.
The Effectiveness of Counseling on Mothers' Typhoid Prevention Knowledge among Pediatrics’ Inpatients: The Effectiveness of Counsling on Mother’s Typhoid Prevention Knowledge Among Pediatrics’ Inpatients Adhi Permana; Rika Agustina; Putri Amaliah Badri; Thia Prameswarie; Ahmad Ghiffari
Jurnal Surya Medika (JSM) Vol. 11 No. 3 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i3.9520

Abstract

Worldwide, typhoid disease affects between 11 and 20 million individuals annually. The risk is higher for men, for those with less education, and for those less than fourteen years old. This study aims to examine the impact of counseling on typhoid prevention knowledge among patients at Muhammadiyah Hospital. A pre-experimental one-group pretest-posttest approach was employed to interview 30 participants to evaluate their knowledge levels prior to and following counseling. The Marginal Homogeneity Test indicated a rise in average knowledge levels from 2.03 to 2.80. The findings indicated that counseling enhances understanding of typhoid prevention, underscoring the necessity of basic healthcare education for patients and their families.
Co-Authors Adhi Permana Fadhillah Putri Rusdi Putri Amaliah Badri Rika Agustina Risdiansyah Risdiansyah Rury Tiara Oktariza Thia Prameswarie