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Perbandingan Kadar Glukosa dan C-Reactive Protein (CRP) pada Lansia Obesitas dan Non-obesitas di Komunitas Griya Lansia Aisyiyah Baiturrohmah Yogyakarta Kintawarmi Kintawarmi; Nazula Rahma Shafriani; Widaninggar Rahma Putri
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 3 (2025): Juli 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i3.6006

Abstract

Obesity is a condition of impaired body weight control system indicated by excessive fat accumulation in the body (i.e., exceeding 20% of ideal body weight) which can cause increased blood glucose levels and systemic inflammation. Obesity assessment can be measured using the Body Mass Index (BMI) and Waist Circumference Ratio (WC). The purpose of this study was to analyze the differences in glucose and CRP levels between obese and non-obese elderly in the Aisyiyah Baiturrohmah Elderly Home Community. This research method is comparative analytical observational, to see the comparison of Glucose and CRP levels in obese and non-obese elderly. The sample collection technique used the total sampling method with a cross-sectional approach with a total sample of 31 elderly (17 obese elderly and 14 non-obese elderly). The results of the study were in the form of primary data from the results of glucose examinations using the Point of Care Test method and CRP examinations using the latex agglutination method. The results of statistical analysis of glucose examinations using the one sample t-test showed a p-value of 0.001 which indicated a significant difference between obese and non-obese glucose levels. Meanwhile, statistical tests were not carried out on CRP because all samples were found to be non-reactive, so it was stated that no significant difference was found between the CRP of obese elderly and the CRP of non-obese elderly
Identifikasi Bakteri Staphylococcus Aureus pada Spons Make-Up di Kalangan Mahasiswa Putri Maharani; Wiwit Probowati; Widaninggar Rahma Putri
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2026): Agustus 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i3.7918

Abstract

Makeup sponges are porous cosmetic application tools that are reused and can potentially become a breeding ground for microorganisms if not cleaned regularly. One bacterium that can contaminate makeup sponges is Staphylococcus aureus, which are knew to do play with a role in various skin also soft tissue infections. This reseach was purposelly to identifying the presence of S. aureus towards makeup sponges used by college students. The study employed a quantitative experimental method using purposive sampling on 30 samples of makeup sponges that had been used for at least 1–2 months. Samples were grouped based on washing frequency: frequently washed, rarely washed, and never washed. Bacterial identification was performed via inoculation on Mannitol Salt Agar (MSA) medium, followed by subculturing, Gram staining, catalase testing, and coagulase testing. The results of the study showed colony growth on MSA medium, indicated by a yellow discoloration of the medium. Gram staining revealed coccus-shaped cells arranged in clusters and stained purple, indicating the characteristics of Gram-positive bacteria. The catalase and coagulase tests yielded positive results, confirming the presence of Staphylococcus aureus. Of the 30 samples examined, 7 positive samples were found in the group of sponges that were rarely washed, 6 positive samples in the group that were never washed, and 3 positive samples in the group that were frequently washed. These findings indicate that S. aureus contamination is more common in sponges that are rarely or never washed compared to those cleaned regularly.
Hubungan Karakteristik Pasien dengan Hasil GeneXpert dan Resistensi Rifampisin Suspek TB di RSUD dr. Tjitrowardojo Purworejo Rahmat Frulianto Z. Datukaramat; Widaninggar Rahma Putri; Wiwit Probowati
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 7, No 3 (2026)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v7i3.16616

Abstract

Tuberculosis (TB) remains a major global health problem significantly high disease burden. The GeneXpert Molecular Rapid Test is a diagnostic method capable of rapidly detecting Mycobacterium tuberculosis (MTB) and rifampicin resistance. Patient characteristics may be associated with MTB detection and rifampicin status. To analyze the association between GeneXpert molecular rapid test result and patient characteristics among suspected tuberculosis patient tuberculosis patients at dr. Tjitrowardojo Hospital, Purworejo, in 2025. An analytical observational study with a cross-sectional design was conducted using medical record data from 606 suspected TB patients who underwent GeneXpert testing from January to December 2025. Data were analyzed using Chi-Square, Fisher’s Exact Test, and Likelihood Ratio tests with significance level of p<0,05. MTB was detected in 97 patients (16,0%) and not detected in 509 patients (84,0%). Rifampicin-sensitive TB was identified in 94 patients (96,9%), while rifampicin-resistant TB was found in 3 patients (3,1%). Age group (p<0,001), DM (p<0,001), and HIV comorbidity (p<0,001) were significantly associated with MTB detection. Sex was not signiassociated with MTB detection (p=0,671). No significant association was found between patient characteristics and rifampicin status (p>0,05). Age group, DM, and HIV were significantly associated with GeneXpert MTB results, whereas sex was not. None of the studied patient characteristics were associated with rifampicin resistance status.
Perbandingan Efektivitas Antibakteri Pada Ekstrak Cinnamomum verum dan Cinnamomum cassia Terhadap Methicillin Resistant Staphylococcus aureus (MRSA) Aisyah Ramadhani Fawzan; Dhiah Novalina; Widaninggar Rahma Putri
Jurnal Analis Farmasi Vol 11, No 2 (2026): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v11i2.26235

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) merupakan salah satu penyebab utama infeksi dengan tingkat resistensi tinggi terhadap berbagai antibiotik. Penggunaan antibiotik lini pertama seperti vancomycin berpotensi menimbulkan efek samping, sehingga diperlukan alternatif antibakteri dari bahan alami. Kayu manis diketahui memiliki aktivitas antibakteri yang berasal dari kandungan cinnamaldehyde. Penelitian ini bertujuan untuk mengevaluasi aktivitas antibakteri serta membandingkan efektivitas ekstrak Cinnamomum verum dan Cinnamomum cassia terhadap MRSA.Ekstrak diperoleh melalui metode maserasi menggunakan etanol 96% dan dibuat dalam konsentrasi 75%, 85%, dan 95% menggunakan DMSO 10%. Uji aktivitas antibakteri dilakukan dengan metode disc diffusion, kemudian dianalisis menggunakan Two-Way ANOVA dan uji lanjut Tukey HSD.Hasil penelitian menunjukkan bahwa diameter zona hambat meningkat seiring dengan peningkatan konsentrasi ekstrak. Zona hambat terbesar diperoleh pada konsentrasi 95%, yaitu sebesar 14,23 mm pada ekstrak C. verum dan 14,09 mm pada ekstrak C. cassia. Namun, hasil analisis statistik menunjukkan tidak terdapat perbedaan yang signifikan (p0,05) baik berdasarkan jenis ekstrak, konsentrasi, maupun interaksi keduanya. Berdasarkan hasil tersebut, dapat disimpulkan bahwa ekstrak etanol C. verum dan C. cassia memiliki aktivitas antibakteri terhadap MRSA dengan efektivitas yang relatif setara.