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All Journal Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Alfina Nurrahman
Sekolah Tinggi Ilmu Kesehatan Tujuh Belas, Karanganyar, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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COMPARISON OF VITAMIN C EXTRACTION FROM YELLOW AND ORANGE PAPRICA USING ETHANOL AND METANOL SOLVENTS Jamilah Hamidi Yanti; Rifkarosita Putri Ginaris; Alfina Nurrahman
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 17 No 2 (2025): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v17i2.2848

Abstract

Paprika mengandung jumlah vitamin C yang signifikan, paprika dikenal karena khasiatnya yang sangat bermanfaat bagi kesehatan, termasuk kemampuannya untuk menangkal radikal bebas dan bertindak sebagai antioksidan bagi tubuh. Studi ini menggunakan pelarut etanol dan metanol untuk mengukur kandungan vitamin C pada  paprika oranye dan kuning. Penelitian ini dilakukan di Laboratorium Kimia Universitas Trunojoyo Madura pada Januari 2025. Menggunakan etanol dan metanol sebagai pelarut, prosedur maserasi digunakan untuk mengekstrak paprika. Panjang gelombang maksimum juga ditentukan. Pemeriksaan sampel ini menunjukkan ymax sebesar 373,5 nm. Persamaan y = 0,0006 x + 0,019 menunjukkan linearitas. Analisis kuantitatif dilakukan pada rentang panjang gelombang 250–400 nm menggunakan spektrofotometri UV-Vis. Pelarut etanol menghasilkan 340 mg/100 g vitamin C pada paprika kuning, sedangkan pelarut metanol menghasilkan 562,5 mg/100 g. Pelarut etanol menghasilkan 215 mg/100 g vitamin C dari paprika oranye, sedangkan pelarut metanol menghasilkan 562,5 mg/100 g. Hasil uji desain blok kelompok acak lengkap dengan y = 0,05 menunjukkan perbedaan yang signifikan dalam jumlah vitamin C yang terdapat pada setiap sampel.
FORMULATION AND EVALUATION OF THE PHYSICAL QUALITY OF NIACINAMIDE GEL PREPARATIONS USING PVP AS A GELLING AGENT Shohihunnatiq Zulananta; Rifkarosita Putri Ginaris; Alfina Nurrahman
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 17 No 2 (2025): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v17i2.2883

Abstract

Niacinamide is the amide form of vitamin B3. Other forms of vitamin B3 include niacin (nicotinic acid). Polyvinylpyrrolidone (PVP) is a biodegradable and air-soluble polymer derived from the monomer N-vinylpyrrolidone. Gels are water-rich preparations and have better potential as topical drug delivery preparations compared to ointments because they are non-sticky, require low energy during formulation, are stable, and have aesthetic value. The purpose of this study was to evaluate the physical qualities of PVP-based niacinamide gel preparations based on physical quality parameters, including organoleptic test, ligninogenicity test, pH test, viscosity test, adhesiveness test, and spreading power test. The method used in this study was an experimental method carried out to determine the physical qualities of a good gel. The results of the study showed that the PVP-based niacinamide gel preparation produced had a thick gel texture, transparent color, odorless, homogeneous, an average pH value of 16.6, an average viscosity value of 2673.6 - 2179.6, an average spreadability value of 6.2 - 6.3, and an average adhesiveness value of 4.67 - 4.46. Based on these results, the PVP-based niacinamide gel preparation had physical quality that met the requirements according to good criteria.
Co-Authors Jamilah Hamidi Yanti Rifkarosita Putri Ginaris Shohihunnatiq Zulananta