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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Sains dan Teknologi Buletin Kedokteran dan Kesehatan Prima Jurnal Rumpun Ilmu Kesehatan Jurnal Kesehatan Amanah PCJN Pharmaceutical and Clinical Journal of Nusantara Journal of Pharmaceutical and Sciences. Jurnal Sains Farmasi dan Kesehatan Jurnal Indah Sains dan Klinis
Ginting, Astriani Natalia Br
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Counseling students to improve fire safety knowledge and preparedness Simanjuntak, Mafe Robbi; Dameria, Dameria; Situngkir, Luwis; Sihombing, Tabita Ronauli; Ginting, Astriani Natalia Br; Sianipar, Milka Rositi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6530

Abstract

This research investigates the effectiveness of counseling methods, incorporating seminar models and PowerPoint presentations, in enhancing students’ knowledge and preparedness for fire emergency response at Universitas Prima Indonesia. A quantitative approach with a quasi-experimental, one-group pretest-posttest design was employed, involving 78 students from the Public Health Bachelor Program. The intervention comprised four counseling sessions covering basic fire knowledge, preparedness steps, emergency actions, and the use of firefighting equipment. Data was collected through questionnaires administered before and after the intervention, assessing students' knowledge of fire extinguishers, hydrants, fire alarms, assembly points, emergency exits, and emergency stairs. The results indicated a significant positive impact, with post-test scores for both knowledge and preparedness substantially higher than pre-test scores (p < 0.001). Before the intervention, only 25.6% of participants demonstrated good knowledge, while after the intervention, 97.4% achieved this level. Similarly, preparedness levels significantly increased, with 97.4% of participants feeling ready after the intervention compared to only 19.2% before. The study underscores the effectiveness of the implemented counseling methods and supports the recommendation for continuous fire safety education to ensure sustained preparedness.
Factors associated with self-medication practices of primary dysmenorrhea among students Sembiring, Ernesta Br.; Siburian , Friska Lasro Yanti; Suci, Tri; Ginting, Astriani Natalia Br
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6777

Abstract

Self-medication and home remedies are the most frequently used methods to relieve menstrual discomfort among female college students. The practice of self-medication varies among adolescent female students. Therefore, this study aimed to observe and analyze the factors associated with the practice of self-medication for primary dysmenorrhea among university students.This study used an analytical observational design with a cross-sectional approach, involving 207 female health students from Universitas Prima Indonesia. The sample was obtained through a purposive sampling technique. Data analysis included univariate analysis, bivariate analysis (chi-square and Fisher's exact test), and multivariate analysis (logistic regression). The prevalence of self-medication was reported to be 36.7%. Several factors were found to be associated with self-medication practices for primary dysmenorrhea among students, namely menstrual cycle (p<0.001, OR: 3.27, 95% CI 1.75-6.10), duration of pain during menstruation (p<0.001 OR: 3.85, 95% CI 2.10-7.07), and severity of pain (p=0.009 OR: 2.21, 95% CI 1.24-3.93). In contrast, age (p=0.316), academic year (p=0.889), family history (p=0.470), age at menarche (p=0.223), and menstrual duration (p=0.552) did not show a statistically significant association with self-medication practices for primary dysmenorrhea. The dominant factor influencing self-medication practices for primary dysmenorrhea was pain duration. Notably, self-medication with medications was found to be relatively low among health students with primary dysmenorrhea. Therefore, educational programs that address the limitations of self-medication with drugs need to be implemented effectively.
Factors influencing self-medication behaviour among non-health science students at Universitas Prima Indonesia Damanik, Dedech M. Sari; Siregar, Nur Aini; Paulina, Roslina; Suci, Tri; Ginting, Astriani Natalia Br
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6784

Abstract

Self-medication, defined as the use of medication without a prescription or professional guidance, is a global phenomenon with significant implications for both individual and public health. This behaviour is frequently motivated by the desire to alleviate minor ailments, avoid healthcare costs, or circumvent lengthy consultation waiting times. While it can constitute a component of responsible self-care, self-medication also carries risks such as adverse drug reactions, drug interactions, antibiotic resistance, and the potential for misuse. This research aimed to analyse the factors associated with self-medication behaviour among non-healthcare students at Universitas Prima Indonesia. The study employed an analytical observational design with a cross-sectional approach. Data were collected via an online questionnaire distributed to 188 undergraduate students from the Faculty of Economics at Universitas Prima Indonesia, selected using simple random sampling. The independent variables in this study were gender, knowledge of self-medication, peer recommendations, and academic stress, while the dependent variable was self-medication behaviour. Data analysis involved univariate statistics to describe the characteristics of each variable and bivariate analysis using the Chi-squared test to examine the relationships between variables. The results indicated that knowledge (OR=3.230; p=0.000), peer recommendations (OR=2.046; p=0.000), and academic stress (OR=1.552; p=0.002) were significantly associated with self-medication, whereas gender was not (p=0.126). It can be concluded that a lack of knowledge, peer influence, and academic stress increase the risk of self-medication. Educational interventions and mental health support are necessary to reduce unsafe self-medication practices.
TINGKAT PENGETAHUAN DAN SIKAP MAHASISWA FARMASI UNPRI TERHADAP PENGGUNAAN OBAT DIABETES MELITUS TIPE 2 Amelia, Ade; Ginting, Astriani Natalia Br; Meutia, Rena; Lubis, Asyrun Alkhairi
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.44811

Abstract

Diabetes melitus (DM) adalah suatu kondisi kronis yang terjadi ketika pankreas tidak dapat lagi memproduksi insulin atau tubuh tidak dapat menggunakan insulin secara efektif. Penyakit DM diklasifikasi menjadi beberapa bagian, termasuk DM tipe 2 yang umum terjadi pada usia dewasa dan dapat dipicu oleh obesitas dan faktor keturunan serta berisiko menyebabkan komplikasi jika tidak dikendalikan. Mahasiswa farmasi berperan dalam edukasi dan pelayanan kesehatan, sehingga tingkat pengetahuan dan sikap mahasiswa farmasi terhadap penggunaan obat DM tipe 2 sangat penting. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan dan sikap mahasiswa farmasi UNPRI terhadap penggunaan obat DM tipe 2 guna mendukung pengelolaan penyakit secara efektif. Penelitian ini dilakukan di Universitas Prima Indonesia menggunakan desain penelitian deskriptif dengan teknik pengambilan data yaitu data primer yang dikumpulkan menggunakan kuesioner yang dibagikan kepada mahasiswa farmasi UNPRI. Data dianalisis secara univariat menggunakan aplikasi spss versi 27. Terdapat total 100 responden yang termasuk dalam penelitian ini. Didapatkan sebagian besar responden merupakan perempuan dan berusia 17-19 tahun. Berdasarkan tingkat pengetahuan mahasiswa kategori Baik 88 orang (88.0%), kategori Cukup Baik 7 orang (7.0%), dan kategori Kurang Baik 5 orang (5.0%) dan tingkat sikap mahasiswa kategori Baik berjumlah 44 orang (44.0%), kategori Cukup Baik 50 orang (50.0%), dan kategori Kurang Baik berjumlah 6 orang (6.0%). Berdasarkan hasil penelitian ini dapat disimpulkan bahwa tingkat pengetahuan dan sikap mahasiswa farmasi UNPRI tentang penggunaan obat diabetes melitus tipe 2 sebagian besar baik, namun sikap mereka cenderung cukup baik. 
An evaluation of patient satisfaction with pharmaceutical services at Munyang Kute Regional General Hospital Bengimiate, Nuriza; Hartopo, Haqi; Razoki, Razoki; Ginting, Astriani Natalia Br
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7173

Abstract

Patient satisfaction is a crucial indicator for assessing hospital service quality, in which pharmaceutical services play a vital role as a primary point of contact with patients. This study aimed to comprehensively evaluate the satisfaction level of outpatients with the pharmaceutical services at Munyang Kute Regional General Hospital. This research employed a descriptive quantitative design with a cross-sectional approach. A total of 90 respondents were selected through a purposive sampling technique based on predetermined criteria. The research instrument was an adapted questionnaire designed to measure satisfaction across five dimensions of service quality: tangibles, reliability, responsiveness, assurance, and empathy. The collected data were analyzed descriptively using SPSS software. The findings indicated that patients were generally satisfied with the pharmaceutical services they received. The highest level of satisfaction was observed in the responsiveness dimension, with a percentage of 69.72%. The other dimensions, in descending order, were tangibles (32.21%), empathy (27.19%), assurance (19.60%), and the lowest was the reliability dimension (16.00%). Overall, the patient perception of pharmaceutical services at Munyang Kute Regional General Hospital is positive. Nevertheless, there remains room for improvement, particularly in the reliability and assurance dimensions. Continuous quality improvement through enhanced patient education and optimization of facilities is highly recommended.
Evaluation of Antidiabetic Drug Selection and Dosage Appropriateness in Hospitalized Type 2 Diabetes Mellitus Patients at RSU Royal Prima Medan. January-June 2024 Purba, Helprida GM; Yunus, Muhammad; Ginting, Astriani Natalia Br
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 3 No. 03 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i02.105

Abstract

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that requires appropriate drug management to achieve optimal blood glucose control. Appropriateness of drug and dose is essential to ensure the effectiveness of therapy. while cost-effectiveness analysis is needed to assess the efficiency of resource use in its management. This study aims to assess the appropriateness of the use of drugs and doses of type 2 antidiabetics based on PERKENI 2021 clinical guidelines and analyze the cost-effectiveness of therapy in hospitalized patients. This study used a retrospective descriptive method with a cross-sectional approach. The research was conducted in January-February 2025 using purposive sampling technique.The result of the 43 patients. the majority were female (55.8%) and aged 56-65 years (48.8%). The suitability of drug use in accordance with PERKENI 2021 reached 100%. but there was a dose discrepancy of 1.36%. namely the drug sitagliptin. Based on ACER and ICER parameters. the most cost-effective monotherapy is Glimepirid with an effectiveness value of 100%. an ACER value of IDR 83.886.43. while the most cost-effective combination therapy is Pioglitazon + metformin with an effectiveness value of 100%. an ACER value of IDR 100.639.21 and an ICER value of IDR 76.734.39 and IDR 13.317.37. Most of the therapies are in accordance with the PERKENI 2021 guidelines. but dosage accuracy still needs to be improved.
Formulation and Evaluation of Avocado Leaf Extract Cream Preparation (Persea americana Mill.) Sitanggang, Titin Krisdayanti; Yunus, Muhammad; Ginting, Astriani Natalia Br
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 3 No. 03 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i02.106

Abstract

As the outermost organ of the body, the skin is vulnerable to disorders such as inflammation, infection, and irritation, necessitating the use of effective and safe topical preparations. Avocado leaves (Persea americana Mill.) contain bioactive compounds such as flavonoids and polyphenols with known antioxidant and anti-inflammatory properties. This study aimed to formulate and evaluate a cream preparation containing ethanolic extract of avocado leaves as a natural active ingredient. The extract was obtained by maceration using 96% ethanol and formulated into three concentrations: 10% (F1), 15% (F2), and 20% (F3). Evaluations included organoleptic properties, homogeneity, pH, spreadability, and physical stability. The results showed that all formulations had a homogeneous appearance, characteristic color according to extract concentration, were odorless and tasteless. The pH values ranged within a safe range for skin application (4.83–4.90), and the best spreadability was observed in formulation F2. Increasing extract concentration tended to decrease spreadability due to increased viscosity. All formulations demonstrated good physical stability during cyclic stability testing. Based on these findings, it can be concluded that avocado leaf ethanolic extract can be effectively formulated into a stable, safe, and physically acceptable cream suitable for topical use.
Activity Test Of Salam Extract (Syzygium polyanthum) On Diabetes Disease Using White Rats (Ratus Novergicus) Hikmad Elsi Enoni Harefa; Astriani Natalia Br Ginting; Rena Meutia; Nerly Juli Pranita Simanjuntak
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 1 (2025): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i1.2609

Abstract

Diabetes Mellitus is a chronic metabolic disease characterized by elevated blood sugar levels due to impaired secretion or action of insulin. The use of herbal plants such as as salam leaves (syzygium polyanthum) is one of the alternative treatment methods. This study aims to evaluate the effectiveness and optimal dosage of salam leaf extract in lowering blood glucose levels in male rats (Rattus Novergicus) induced by alloxan. A total of 30 rats we divided into six groups: normal control, negative control, positive control (metformin), and three treatment groups with extract doses of 200, 300, and 400 Mg/KgBB. Blood glucose levels were measured on days 15,20,25, and 30. Data were analyzed using ANOVA with a significance level of 95%. The results show that salam leaf extract significantly lowers blood glucose levels, with the most effective dose being 400 Mg/KgBB. This study supports the potential of salam leaves as an effective, safe, and affordable natural antidiabetic agent.
Evaluasi Kesesuaian Obat Dan Dosis Antihipertensi Pada Pasien Hipertensi Rawat Jalan Di Rumah Sakit Royal Prima Sosa Ester Kristiani Lase; Muhammad Yunus; Astriani Natalia Br Ginting
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 1 (2025): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i1.3252

Abstract

This study was conducted to assess the appropriateness of antihypertensive medication selection and dosage and to analyze the cost-efficiency of therapy in outpatients with hypertension at Royal Prima Hospital, Medan. This study used a retrospective descriptive method, with data collected from the medical records of 42 patients. Evaluation of therapy effectiveness and costs was conducted using a Cost-Effectiveness Analysis (AEB) approach, calculating the Average Cost-Effectiveness Ratio (ACER) and the Incremental Cost-Effectiveness Ratio (ICER). Symptoms associated with hypertension can be avoided by reducing excess weight (obesity), controlling salt intake, engaging in regular physical activity, quitting smoking, and taking medication regularly. A hypertension prevalence survey found that the prevalence of hypertension in Indonesia among the population aged 18 years and over is 31.3% for men and 31.9% for women, out of the total population aged 18 years and older. In 2008, the number of hypertension sufferers reached 32%, with the majority of patients aged > 25 years. The results showed that all patients (100%) received appropriate antihypertensive therapy based on standard clinical guidelines, both in terms of drug selection and dosage. The most commonly used drug combination was ARB and CCB, found in 23.81% of patients. The combination of a non-DHP CCB + ARB + ​​loop diuretic + alpha-blocker demonstrated the highest therapeutic effectiveness (100%) with the lowest average cost of IDR 680,000, thus being considered the most cost-effective regimen according to the ICER analysis. Meanwhile, several other therapy combinations that required higher costs but provided less effectiveness were categorized as cost-inefficient. These findings emphasize the importance of rational evaluation of antihypertensive therapy, particularly in terms of treatment appropriateness and cost-efficiency, to support optimal clinical outcomes and appropriate resource utilization.
Effectiveness of transdermal patch formulation of Hibiscus rosa-sinensis L. leaf extract as an antipyretic in male rats induced with DPT vaccine Ketaren, Nessya Try Natasya Br; Ginting, Astriani Natalia Br; Meutia, Rena; Lubis, Asyrun Alkhari
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7546

Abstract

Fever is characterized by an elevation of body temperature above the normal range of 37.5°C and represents a physiological response to various health conditions such as infections or other diseases. Antipyretic drugs, including paracetamol and ibuprofen, are commonly used to manage fever. Ethanol extract of Hibiscus rosa-sinensis L. (kembang sepatu) leaves contains bioactive compounds such as tannins, flavonoids, saponins, carbohydrates, steroids, phenols, glycosides, quinones, terpenoids, cyclopeptides, and alkaloids, which may confer natural antipyretic properties. In this study, 3% and 5% (w/w) Hibiscus rosa-sinensis leaf ethanol extracts were formulated into transdermal patches and evaluated for their antipyretic efficacy in male rats induced with the Diphtheria-Pertussis-Tetanus (DPT) vaccine. The dried Hibiscus rosa-sinensis leaves were macerated using 96% ethanol. The concentrated extract was formulated into a hydroxypropyl methylcellulose (HPMC)-based transdermal patch. Phytochemical screening of the extract, stability testing of the transdermal patch, and statistical analysis of the antipyretic effect on DPT-induced male rats were conducted. Phytochemical screening of the 96% ethanol extract confirmed the presence of alkaloids, flavonoids, tannins, steroids, and saponins. The transdermal patch formulation demonstrated good stability over 21 days of storage. The 5% extract patch exhibited the highest antipyretic activity, significantly reducing fever in the experimental rats and showing effectiveness comparable to the positive control (paracetamol).
Co-Authors Amelia, Ade Asyrun Alkhairi Lubis Asyrun Alkhairi Lubis Bengimiate, Nuriza Chrismis Novalinda Ginting Daimah W. S. Harahap Damanik, Dedech M. Sari DAMERIA DAMERIA Elvi Sasmi Farren Farren Gusbakti Rusip Hartopo, Haqi Hikmad Elsi Enoni Harefa Hotvera Merianis, Hotvera Ketaren, Nessya Try Natasya Br Linda Chiuman Lubis, Asyrun Alkhari Masriani Merianis, Hotvera Meutia, Rena Milka Rositi Sianipar Muhammad Yunus Nerly Juli Pranita Simanjuntak Novitaria Br Sembiring Paulina, Roslina Purba, Helprida GM Putri Andari Razoki Razoki Razoki, Razoki Rena Meutia Rena Meutia Roy Indrianto Bangar S Sembiring, Ernesta Br. Siburian , Friska Lasro Yanti Sihombing, Tabita Ronauli Simanjuntak, Mafe Robbi Siregar, Nur Aini Sitanggang, Titin Krisdayanti Situngkir, Luwis Sosa Ester Kristiani Lase Suci, Tri Tiara Fortuna A.R Vera Estefania Kaban