Nova Rianti Marbun
Institut Kesehatan Deli Husada

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FORMULASI SEDIAAN LILIN EKSTRAK MINYAK ATSIRI BUNGA SEDAP MALAM (Polianthes tuberosa ) SEBAGAI AROMATERAPI Nova Rianti Marbun; Tio Ranti Sari Br Sembiring
Jurnal Penelitian Farmasi & Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i2.2944

Abstract

This study aims to formulate and evaluate aromatherapy wax preparations from nightshade flower essential oil extract (Polianthes tuberosa) as an effort to handle non-pharmacological stress. The essential oil of the nightshade flower is obtained through the method of steam distillation from 10 kg of fresh flowers, resulting in 30 ml of essential oil. The characterization of simplicia showed a moisture content of 5.71%, a water soluble cider content of 17.13%, an ethanol soluble cider content of 18.01%, a total ash content of 10.82%, and an acid-insoluble ash content of 1.49%, meeting the requirements of the Indonesian Herbal Pharmacopoeia. Phytochemical screening identifies alkaloids, flavonoids, tannins, saponins, triterpenoids, and glycosides. Aromatherapy candles are formulated in four variations of essential oil concentrations (Polianthes tuberosa): 0% (F0), 5% (F1), 10% (F2), and 15% (F3), as well as one positive control (F4). Physical evaluation shows all formulas have a good, dense, and air bubble-free appearance. The hedonic test showed that the F3 formula (15% essential oil) was preferred by the panelists in terms of aroma, shape, and color, and provided a significant relaxation and refreshment effect, close to the quality of commercial products. The F3's burn time reaches 10 hours, showing good durability.
FORMULASI DAN EVALUASI SEDIAAN PASTA GIGI EKSTRAK BIJI ALPUKAT (Persea americana Mill.) Nova Rianti Marbun; Tio Ranti Sari Br Sembiring; Evi Depiana Gultom
Jurnal Penelitian Farmasi & Herbal Vol. 9 No. 1 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/cp93q767

Abstract

“Extrinsic tooth stains caused by the consumption of coffee, tea, and smoking habits can reduce dental aesthetics. One approach to help overcome this problem is the use of toothpaste containing natural active ingredients. Avocado seeds (Persea americana Mill.) contain various secondary metabolites that have the potential to be used as active ingredients in toothpaste preparations. This study aimed to formulate and evaluate toothpaste containing ethanol extract of avocado seeds and to determine the effectiveness of different extract concentrations in helping to remove extrinsic tooth stains in vitro. This experimental study included crude drug characterization, phytochemical screening, extraction of avocado seeds using the maceration method with 70% ethanol, formulation of toothpaste with extract concentrations of 3.25%, 6.25%, and 12.25%, and evaluation of the physical quality, including organoleptic properties, homogeneity, pH, spreadability, foam height, and viscosity. The effectiveness of tooth stain removal was evaluated in vitro using a UV-Vis spectrophotometer by measuring the absorbance of the tooth stain washing solution. Phytochemical screening showed that the ethanol extract of avocado seeds contained alkaloids, flavonoids, tannins, saponins, and steroids. All toothpaste formulations met the requirements for physical quality and stability evaluation. The cleansing test showed that F1 containing 3.25% avocado seed extract had the highest stain removal effectiveness at 48.36%, followed by F2 at 26.22% and F3 at 8.19%. Based on the results, ethanol extract of avocado seeds (Persea americana Mill.) can be formulated into a toothpaste preparation that meets the requirements for physical quality and stability and has the potential to help remove extrinsic tooth stains. The F1 formulation containing 3.25% avocado seed extract demonstrated the best cleansing effectiveness in this study.”