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PENGARUH PEMBERIAN EKSTRAK ETHANOL BIJI BUAH PINANG (ARECA CATECHU L.) TERHADAP PERTUMBUHAN STAPHYLOCOCUS AUREUS SECARA IN VITRO Baiti, MIftakhul; Elfrida, Solha; Lipinwati, Lipinwati
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 6 No. 1 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (522.093 KB) | DOI: 10.22437/jmj.v6i1.4817

Abstract

ABSTRACT Background: Infectious disease is known as a global concern because of the irrational, excessive and long term use of antibiotics especially in Staphylococcus aureus infection. The unecessarily use of antibiotics can creat a resistance issue such as MSSA, MRSA, VISA and VRSA. So as a new alternative that is being developed in medicine, herbal plants are used. Areca nut (Areca catechu. L) is a herbal plant that is found in Indonesia, especially in Province of Jambi, betel nut is one of the best in the world. The aim of this study are to investigate phytochemical components and inhibition effect Staphylococcus aureus ATCC 25923 using dry ethanol extract of betel nuts at concentrations 20%, 30%, 40% and 50% in vitro. Method: Antibacterial sensitivity tests against Staphylococcus aureus ATCC 25923 were performed using dry ethanol extract of betel nuts (Areca catechu. L) with various concentrations on each group. Group I is treated nut with a concentration of 20%, Group II with a concentration of 30%, Group III with a concentration of 40%, Group IV with a concentration of 50%, the group V as a negative control (distilled) and group VI as a positive control that was given amoxicillin clavulanate 30μg. Then the inhibitory effects of these treatments are measeure and classified by the Davis and Stout classification in 1971. The data analysis began with Saphiro Wilk test and then with levent test statistic. Because distributed data is not normal, the analysis continued with Kruskal Wallis test and Post Hoc test. Results: Results of this study showed that the ethanol extract of betel nuts can inhibit the growth of S. aureus, which is a concentration of 20% with a diameter of 13,63mm, concentration of 30% with a diameter of 15mm, concentration of 40% with a diameter of 15,5mm, concentration of 50% with a diameter of 14,7mm compared to the positive control 30μg amoxicillin clavulanate in inhibiting the growth of S. aureus with a diameter of 34,25mm. Conclusion: The ethanol extract of betel nuts can inhibit the growth of Staphylococcus aureus in vitro. Areca seed extract with concentration of 40% is the optimum concentration to inhibit the growth of Staphylococcus aureus. Keywords: Staphylococcus aureus, Areca catechu. L, Sensitivity Test. ABSTRAK Latar Belakang : Penyakit infeksi merupakan masalah yang menjadi perhatian global, oleh karena penggunaan antibiotik yang irasional, berlebihan dan dalam jangka waktu yang lama, terurama infeksi yang disebabkan oleh Staphylococcus aureus. Hal ini dapat menimbulkan masalah baru resistensi antibiotik seperti MSSA, MRSA, VISA dan VRSA. Maka sebagai alternatif baru yang sedang dikembangkan dalam pengobatan yaitu dengan menggunakan tanaman herbal. Pinang (Areca catechu. L) merupakan tanaman herbal yang banyak ditemukan di Indonesia terutama Propinsi Jambi, pinang ini merupakan salah satu pinang terbaik di dunia. Tujuan dari penelitian ini adalah untuk mengetahui komponen fitokimia dan daya hambat ekstrak ethanol biji buah pinang terhadap pertumbuhan Staphylococcus aureus ATCC 25923 secara in vitro pada konsentrasi 20%, 30%, 40% dan 50%. Metode : Ekstrak ethanol biji buah pinang kering (Areca catechu. L) dilakukan uji sensitifitas antibakteri terhadap Staphylococcus aureus ATCC 25923 dengan berbagai konsentrasi pada masing – masing kelompok. Kelompok I yaitu perlakuan pinang dengan konsentrasi 20%, kelompok II dengan konsentrasi 30%, kelompok III dengan konsentrasi 40%, kelompok IV dengan konsentrasi 50%, kelompok V sebagai kontrol negatif (Aquades) dan kelompok VI sebagai kontrol positif dengan diberikan Amoksisilin Klavulanat 30µg. Kemudian diukur efek inhibisi dari perlakuan tersebut dan digolongkan berdasarkan penggolongan Davis and Stout 1971. Analisis data diawali dengan uji Saphiro-Wilk dan dilanjutkan dengan uji Levene, oleh karena data terdistribusi tidak normal maka dilakukan uji Kruskal Wallis dan uji Post Hoc. Hasil : Hasi penelitian menunjukkan bahwa ekstrak ethanol biji buah pinang dapat menghambat pertumbuhan S. aureus, yaitu konsentrasi 20% dengan diameter 13,63mm, konsentrasi 30% dengan diameter 15mm, konsentrasi 40% dengan diameter 15,5mm, konsentrasi 50% dengan diameter 14,7mm. Terdapat pengaruh Areca catechu. L dalam menghambat pertumbuhan Staphylococcus aureus ATCC 25923. Kesimpulan : Ekstrak ethanol biji buah pinang dapat menghambat pertumbuhan Staphylococcus aureus secara in vitro. Konsentrasi ekstrak biji buah pinang 40% merupakan konsentrasi optimum dalam menghambat pertumbuhan Staphylococcus aureus. Kata Kunci : Staphylococcus aureus, Areca catechu. L, Uji Sensitifitas.
SKRINING MALARIA DENGAN RAPID DIAGNOSTIC TEST DAN PERILAKU PENGOBATAN MALARIA PADA ORANG RIMBA DI DESA BUKIT SUBAN DAN DESA SEKAMIS KABUPATEN SAROLANGUN TAHUN 2016 Karolina, Maria Estela; Nurmaajid, Oktovia Rezka; Darmawan, Armaidi; Elfrida, Solha
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 6 No. 1 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (407.984 KB) | DOI: 10.22437/jmj.v6i1.4818

Abstract

Abstract Backgrounds : Rapid Diagnostic Test (RDT) is a imunologic methode to diagnose malaria. Mostly, Orang Rimba hunt nomadically. Orang Rimba have traditional medicine to cure malaria. The purposes of this research are to know the incident of malaria based on RDT and malaria treatment behaviour of Orang Rimba. Methode : This research was descriptive study. The populations of this research were Orang Rimba in Desa Bukit Suban and Sekamis, Kabupaten Sarolangun. The number of samples in this research is 49 respondents. The sample was taken by systematic random sampling. Data were analyzed with univariat analysis. Result : The result showed that 16,7 % had malaria positive, P. vivax was the dominat species of plasmodium (62,5%). Mostly the aged of respondent was 5-11 years old (41,7%), the gender was male (58,3%), occupation was doesn’t work (56,3%), marriage status was marriage (56,3%). Most of Orang Rimba had worse knowladge level (53,6%), the mostly used term in Orang Rimba was demam kuro (50%), only (42,9%) respondents knew the trias of malaria, only 9 respondents knew that cause of malaria was mosquito’s bites, Orang Rimba mostly knew the danger of malaria (85,7%) and the complication of malaria (89,3%), and knew that malaria could be cured (82,1%). The users of modern combined with traditional medicine were as much as 57,1%, Orang Rimba mostly used ≥ 3 kinds of traditional medicine 53,6%, traditional medicine was mostly processed by boiling (24 respondents) and mostly knew one way of processing the traditional medicine (57,1%), traditional medicine was mostly for being eaten or drunk and external medicine (50%), the duration of using traditional medicine was mostly 2-3 days (46,4%), Orang Rimba mostly said that traditional medicine was efficacious (92,9%). Conclusions : The incident number of malaria was 16,7% and the mostly users of modern combined with traditional medicine were as much as 57,1%. Keywords : Malaria, RDT, orang rimba, malaria treatment behaviour Abstrak Latar Belakang : Rapid Diagnostic Test (RDT) merupakan metoda imunologik untuk mendiagnosis malaria. Lokasi berburu Orang Rimba cenderung berpindah-pindah. Orang Rimba memiliki kearifan lokal dalam mengobati malaria. Tujuan penelitian ini adalah untuk mengetahui skrining malaria berdasarkan RDT dan perilaku pengobatan malaria pada Orang Rimba. Metode : Penelitian ini merupakan penelitian deskriptif. Populasi penelitian seluruh Orang Rimba yang berada di Desa Bukit Suban dan Sekamis. Jumlah sampel pada penelitian ini adalah 48 responden. Pengambilan sampel menggunakan teknik Systematic Random Sampling. Data dianalisis dengan analisis univariat. Hasil : Dari hasil penelitian didapatkan 16,7% positif malaria, jenis plasmodium yang dominan adalah P. vivax (62,5%). Sebagian besar responden berusia 5-11 tahun (41,7%), sebagian besar berjenis kelamin laki-laki (58,3%), sebagian besar pekerjaan responden tidak bekerja (56,3%), sebagian besar berstatus kawin (56,3%). Sebagian besar Orang Rimba memiliki tingkat pengetahuan kurang baik (53,6%), sebagian besar menggunakan istilah demam kuro untuk menyebutkan malaria (50%), hanya 42,9% yang mengetahui trias malaria, hanya 9 responden yang menjawab penyebab malaria adalah gigitan nyamuk, sebagian besar mengetahui bahaya malaria 85,7%, jenis bahaya malaria 89,3%, dan mengetahui bahwa malaria dapat disembuhkan 82,1%. Pengguna pengobatan modern dikombinasi dengan pengobatan tradisional sebanyak 57,1%, sebagian besar menggunakan ≥ 3 jenis obat tradisional (53,6%), cara pengolahan yang paling banyak dengan cara direbus (24 responden) dan mengetahui 1 cara pengolahan (57,1%), cara pemakaian yang paling banyak dengan dimakan atau diminum dan obat luar (50%), lama penggunaan yang paling banyak selama 2-3 hari (46,4%), sebagian besar mengatakan obat tradisional berkhasiat (92,9%). Kesimpulan : Angka kejadian malaria sebesar 16,7% dan upaya pengobatan malaria terbanyak adalah dengan pengobatan modern dikombinasi dengan pengobatan tradisional (57,1%). Kata Kunci : Malaria, RDT, orang rimba, perilaku pengobatan malaria
Providing Cancer Referral Service Applications for Village Communities Yunike, Yunike; Kusumawaty, Ira; Sri Ananingsih, Esti; Podojoyo, Podojoyo; Elfrida, Solha; Monalisa, Monalisa; Inastyarikusuma, Tarrinni
International Journal Scientific and Professional Vol. 3 No. 2 (2024): March-May 2024
Publisher : Yayasan Rumah Ilmu Professor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56988/chiprof.v3i2.67

Abstract

Cancer is one of the main causes of death in the world, including in Indonesia. Rural communities often face significant challenges in accessing adequate cancer health services, such as distance to health facilities, lack of transportation, and limited trained medical personnel. The research explores the need and potential benefits of providing a cancer referral service application in rural Indonesian communities. The research method used is qualitative with data collection through in-depth interviews and surveys of rural residents. The research results show that rural communities urgently need innovative solutions to overcome gaps in access to cancer health services. Respondents stated that traveling to health facilities in big cities requires significant costs and time so providing a cancer referral service application could be an effective solution. This designed application includes information about nearby health facilities, and mobile health service schedules and allows patients to make appointments and obtain referrals directly through their devices. This research found that the cancer referral service application can increase efficiency and effectiveness in providing cancer health services in rural areas. This application not only facilitates easier and faster access to health services but also raises public awareness regarding the importance of early detection and timely treatment. Active participation of local health workers and support from government and non-government organizations are critical to successfully implementing this application. It can be concluded that providing a cancer referral service application is an urgent need in rural communities in Indonesia. The app is expected to reduce disparities in access to cancer care and potentially save many lives through early detection and timely intervention. Health policies are needed to support the development and dissemination of this application, considering local wisdom and the specific conditions of each region.
Overcoming the Emotional Challenges of Cancer Patients through Psychosocial Support Kusumawaty, Ira; Yunike, Yunike; Inastyarikusuma, Tarrinni; Sri Ananingsih, Esti; Podojoyo, Podojoyo; Elfrida, Solha; Monalisa, Monalisa
International Journal Scientific and Professional Vol. 3 No. 1 (2024): February
Publisher : Yayasan Rumah Ilmu Professor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56988/chiprof.v3i1.68

Abstract

Cancer not only affects the patient's physical condition but also has significant emotional impacts, such as anxiety, depression and stress. Emotional challenges can affect the quality of life and recovery process of cancer patients. This study aims to identify the types of emotional challenges faced by cancer sufferers and explore the effectiveness of psychosocial support in overcoming these challenges. This research method uses a qualitative approach by collecting data through in-depth interviews and questionnaires involving ten cancer patients from various backgrounds. Research results show that cancer sufferers often experience feelings of fear, hopelessness and social isolation. Anxiety about the future, uncertainty about the effectiveness of treatment, and drastic changes in physical and social roles are the main factors causing emotional distress. Psychosocial support, which includes counselling, group therapy, and assistance from mental health professionals, has proven effective in helping patients manage their emotions. This psychosocial intervention can allow patients to express their feelings, get support from fellow patients, and learn effective coping strategies. This research also found that family and community support plays an important role in the emotional recovery process of cancer patients. Active involvement of family members in counselling and therapy sessions can increase the patient's sense of support and reduce the patient's sense of isolation.Additionally, participation in cancer patient support groups helps them feel more understood and emotionally supported. This study concludes that psychosocial support is an important component of comprehensive cancer care. Psychosocial interventions not only help overcome emotional challenges but also contribute to improving the patient's quality of life. Therefore, healthcare programs must include psychosocial support as an integral part of cancer care, ensuring easy and inclusive access for all patients. Supportive health policies and adequate funding are also needed to implement these services effectively and sustainably.
Papaya Gummies as a Nutritional Supplement in Cancer Treatment: A Preliminary Study Podojoyo, Podojoyo; Kusumawaty, Ira; Yunike, Yunike; Sri Ananingsih, Esti; Elfrida, Solha; Monalisa, Monalisa; Inastyarikusuma, Tarrinni
International Journal Scientific and Professional Vol. 3 No. 1 (2024): February
Publisher : Yayasan Rumah Ilmu Professor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56988/chiprof.v3i1.69

Abstract

Cancer is a disease that requires intensive treatment, often accompanied by side effects that affect the patient's appetite and nutritional status. One effort to overcome this problem is to provide dietary supplements that are easy to consume and rich in health benefits. This study explores the potential of papaya jelly candy as a nutritional supplement in cancer treatment. Papaya was chosen because of its high nutritional content, including the enzyme papain which is known to have anti-inflammatory and good digestive properties. This research uses a quantitative approach with an experimental study design. The research sample consisted of 30 cancer patients undergoing chemotherapy in several hospitals. They were divided into two groups: an intervention group that received papaya jelly as an additional supplement and a control group that received standard care without additional supplements. Data was collected through questionnaires, interviews, and measuring nutritional status before and after the intervention over two months. The study results showed that the intervention group who consumed papaya jelly candy had a significant increase in appetite and nutritional status compared to the control group. Patients report that papaya jelly tastes good and is easy to consume, even when they are nauseous from chemotherapy. Laboratory analysis showed that the intervention group had higher antioxidants, which may contribute to increased endurance. The study concluded that papaya jelly candy has great potential as a nutritional supplement in cancer treatment by improving nutritional status and helping improve the quality of life of patients by providing a delicious and easy-to-consume dietary source. Further studies with larger samples and longer intervention periods are needed to confirm these findings and develop guidelines for using papaya gummies in cancer treatment.
The Role of Education and Public Awareness in Preventing Reproductive System Cancer Monalisa, Monalisa; Kusumawaty, Ira; Yunike, Yunike; Sri Ananingsih, Esti; Elfrida, Solha; Podojoyo, Podojoyo; Inastyarikusuma, Tarrinni
International Journal Scientific and Professional Vol. 3 No. 2 (2024): March-May 2024
Publisher : Yayasan Rumah Ilmu Professor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56988/chiprof.v3i2.70

Abstract

Cancers of the reproductive system, including cervical, ovarian, and prostate cancer, are one of the leading causes of morbidity and mortality worldwide. In Indonesia, the incidence of reproductive system cancer is still high, mainly due to low early detection and a lack of public awareness about prevention. This study aims to evaluate the role of education and increasing public awareness in preventing cancer of the reproductive system. This research method uses a quantitative approach with a cross-sectional study design. Data was collected through a survey involving 150 respondents from various backgrounds in three large cities. The research results show that the level of public knowledge about reproductive system cancer is still low. Only 45% of respondents knew the risk factors and early symptoms of reproductive system cancer and only 30% had undergone routine examinations. Health education delivered through various media, including health campaigns, seminars and social media, has effectively increased public awareness and knowledge. Respondents who had participated in health education programs showed significant increases in knowledge and preventive behaviour, such as having regular check-ups and adopting a healthy lifestyle. Research finds that the main obstacles in preventing cancer of the reproductive system are lack of access to health services and low levels of public education, so more inclusive and accessible strategies are needed to disseminate health information. Educational programs involving local communities and community leaders can help overcome these barriers. The research concludes that education and increasing public awareness play a crucial role in preventing cancer of the reproductive system. Implementation of effective education programs can reduce the incidence of cancer through early detection and changes to healthier behaviour. The government and health organizations need to work together to develop and expand health education programs that can be accessed by all levels of society, especially in areas that have low levels of knowledge about cancer of the reproductive system.
Utilization of Kuda Lumping Culture in Reducing Cancer Stigma in Society Sri Ananingsih, Esti; Kusumawaty, Ira; Yunike, Yunike; Elfrida, Solha; M, Monalisa; Inastyarikusuma, Tarrinni; Podojoyo, Podojoyo
International Journal Scientific and Professional Vol. 3 No. 2 (2024): March-May 2024
Publisher : Yayasan Rumah Ilmu Professor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56988/chiprof.v3i2.71

Abstract

Stigma towards cancer is still a significant problem in many communities, including in Indonesia, so it often hampers efforts for early detection, treatment and social support for cancer sufferers. This research aims to explore the use of local culture, especially the Kuda Lumping art, in reducing the stigma of cancer in society. Kuda Lumping was chosen because it is a popular traditional performing art and has a strong appeal among the community. This research method uses a qualitative approach with a case study design. Data was collected through in-depth interviews, participant observation, and surveys of 7 respondents involved in the Kuda Lumping-based education program in Pangkalan Benteng Village. This program involves the Kuda Lumping performance which includes educational messages about cancer, the importance of early detection, and social support for cancer sufferers. The research results show that the integration of health messages in the Kuda Lumping show can effectively reduce the stigma of cancer. Most respondents reported an increase in understanding of cancer and a decrease in negative attitudes towards cancer sufferers after watching the show. In addition, the use of symbols and narratives familiar to the local community makes the message easier to receive and understand. Education through Kuda Lumping also increases community involvement in efforts to prevent and detect cancer early. This research concludes that local cultural approaches such as Kuda Lumping have great potential in overcoming cancer stigma. Traditional art performances combined with health messages can reach various levels of society effectively and convey important information in an engaging and relatable way. Governments and health organizations are encouraged to consider using local arts in public health education programs. This step will not only help reduce stigma but also strengthen community involvement in cancer prevention and treatment efforts.
Exploring the Role of Spiritual Groups in Empowering and Supporting Cancer Patients Elfrida, Solha; Kusumawaty, Ira; Yunike, Yunike; Sri Ananingsih, Esti; Monalisa, Monalisa; Inastyarikusuma, Tarrinni; Podojoyo, Podojoyo
International Journal Scientific and Professional Vol. 3 No. 2 (2024): March-May 2024
Publisher : Yayasan Rumah Ilmu Professor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56988/chiprof.v3i2.72

Abstract

People with cancer not only need medical care but also emotional and spiritual support to face the challenges of their disease. This study aims to explore the role of spiritual groups in empowering and supporting cancer patients and measuring the impact of spiritual interventions on patient well-being. The research uses a qualitative approach with a case study method. Data was collected through in-depth interviews, participant observation, and documentation analysis from three spiritual groups in South Sumatra that actively support cancer patients. The results show that local spiritual groups are important in supporting cancer patients through various means. These groups provide emotional support, spiritual empowerment, and a sense of community that helps patients feel more connected and cared for. Group prayer sessions, meditation and spiritual counselling organized by the group provide inner peace and reduce levels of anxiety and depression in patients. Spiritual groups also help patients find meaning and purpose in their fight against cancer, which strengthens their zest for life and motivation to undergo treatment. Active participation in spiritual activities has been proven to improve the quality of life of cancer patients. Patients report feeling more positive, increased gratitude, and closer relationships with their family members and communities. Spiritual groups also serve as a bridge between patients and other resources and social and medical assistance, which can lighten the patient's overall burden. This research concludes that spiritual groups are crucial in empowering and supporting cancer patients. Structured and ongoing spiritual support can improve patients' emotional and spiritual well-being, contributing to their holistic recovery. Integration of spiritual support in cancer treatment programs is highly recommended. Collaboration between healthcare providers and local spiritual groups can strengthen support systems for cancer patients, ensuring that they receive comprehensive and ongoing care.