This study examines the influence of human resource development, self-efficacy, and work motivation on the work readiness of final-year stu dents, with a focus on the Faculty of Economics and Business. In the context of an increasingly competitive job market, work readiness is a critical factor for students to successfully adapt and excel in professional environments. Human resource development is expected to enhance students’ skills and competencies, self-efficacy reflects their confidence in performing tasks, and work motivation serves as a driving factor for performance and career achievement. The research employed a quantitative survey method, with data collected through structured questionnaires distributed to the entire population of 100 final-year students. The sampling technique used was saturated sampling, whereby all members of the population were included as respondents. Data analysis revealed that human resource development and self-efficacy have a significant and positive effect on work readiness, indicating that both skill enrichment and confidence in one’s abilities play a key role in preparing students for employment. In contrast, work motivation was found to have no significant direct effect on work readiness, suggesting that other factors may mediate or influence the relationship between motivation and readiness to work. Furthermore, the simultaneous influence of human resource development and self-efficacy on work readiness was found to be highly substantial, with a contribution of 96.00%, leaving only 4.00% attributable to other unexamined variables. These findings highlight the importance for educational institutions to prioritize structured programs that build both professional skills and self-confidence among students. Recommendations from this study emphasize the need for competency-based training, mentoring, and targeted motivational strategies to ensure graduates are well-prepared to navigate the demands of the workforce and achieve sustainable career success.