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All Journal Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran
Bena Melinda Purnama
Universitas Muhammadiyah Sumatera Utara
Dentistry Health Professions Public Health

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Evaluasi dan Analisis Hubungan Profil Kepekaan Antibiotik pada Profil Pasien Infeksi Saluran Kemih di RSUD Dr. Pirngadi di Kota Medan Bena Melinda Purnama; Annisa Annisa; Ance Roslina; Hasroni Fathurrahman
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.6907

Abstract

Urinary tract infection (UTI) is one of the most common bacterial infections worldwide, with increasing concern regarding antimicrobial resistance caused by inappropriate antibiotic utilization. This study aimed to evaluate antimicrobial susceptibility patterns and identify factors associated with antibiotic resistance among patients with UTI at Dr. Pirngadi Hospital Medan. An analytical cross-sectional study was conducted involving 57 patients who met the inclusion criteria. Clinical characteristics, urine culture results, bacterial identification, antibiotic administration patterns, and antimicrobial susceptibility profiles were analyzed using the Chi-Square test. The results demonstrated that Escherichia coli was the predominant uropathogen causing UTI (43.9%), followed by Staphylococcus spp. (26.3%), Klebsiella spp. (19.3%), and Sphingomonas paucimobilis (10.5%). Ceftriaxone was the most frequently administered antibiotic (28.1%), followed by ciprofloxacin (22.8%) and meropenem (15.8%). Overall, 66.7% of isolates remained susceptible to tested antibiotics, whereas 33.3% exhibited resistance patterns. Statistical analysis revealed a significant association between urine culture results and antimicrobial susceptibility profiles (p<0.001), as well as between antibiotic administration patterns and bacterial susceptibility (p<0.001). These findings highlight the critical role of microbiological identification and antimicrobial susceptibility testing in guiding rational antibiotic therapy and reducing the emergence of antimicrobial resistance among UTI patients.
Co-Authors Ance Roslina ANNISA . Hasroni Fathurrahman