Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
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This Author published in this journals
All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Academic Hospital Journal
Yanasta Yudo Pratama
Universitas Negeri Yogyakarta
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Cortisol as Biomarker for Stress, Depression, And Physical Activity Among Medical Student: A Systematic Review Yanasta Yudo Pratama; Cerika Rismayanthi; Atikah Rahayu
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 1 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i1.2609

Abstract

Cortisol is one of the most commonly used stress biomarkers. Stress and depression are increasing in young people, especially among college students, especially medical students. Physical activity has been recommended for stress and depression relief, but its effect on cortisol has not been confirmed. This study aims to analyze cortisol measurements for stress, depression, their physical activity among medical student. This literature search utilized PubMed and Google Scholar, combining the keywords "cortisol", "stress", “depression”, “physical activity”, and "medical student" in publications from 2010 to 2025. Ten (10) studies that met our criteria. Most studies use saliva cortisol measurement to assess stress conditions. Our findings suggest cortisol as a measure of stress in medical students, but its contribution to the development of stress and depression remains unclear. There is no correlation between physical activity and cortisol in stress condition. Cortisol measurements can provide an objective test and reflect stress in medical students, but they do not adequately assess acute and stress-related cortisol release. Further studies are needed to assess the effectiveness of cortisol measurements.
The Effect of Physical Activity on Blood Low-Density Lipoprotein Levels: A Systematic Review Yanasta Yudo Pratama; Satria Akbar Putra Asmara
Academic Hospital Journal Vol 8, No 2 (2026): Vol 8, No 2 (2026)
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v8i2.115478

Abstract

Background: Cardiovascular disease is the leading cause of mortality worldwide, with elevated low-density lipoprotein (LDL) cholesterol representing a major modifiable risk factor. Physical activity is widely recommended to improve lipid profiles, although its effects may vary across populations and exercise protocols. This systematic review aimed to synthesize recent evidence on the effects of physical activity on LDL cholesterol levels in diverse populations.Methods: A literature search was conducted in January 2026 using PubMed, Google Scholar, and ScienceDirect for studies published between 2022 and 2025. Study selection followed the PRISMA 2020 guidelines. Methodological quality was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Tools and the Cochrane Risk of Bias tool.Results: Ten studies met the eligibility criteria, involving individuals with diabetes or prediabetes, university students, heart failure, pregnancy, childhood populations, multiple sclerosis, and older adults. Six studies (60%) reported significant reductions in LDL levels following structured physical activity, including aerobic exercise, high-intensity interval training (HIIT), resistance training, and diabetes-specific exercise. Greater benefits were generally observed with supervised moderate-to-vigorous exercise performed for 30–60 minutes per session, 3–5 times weekly, for 8 weeks to 6 months. However, findings were inconsistent in university students and pregnant women.Conclusion: Structured and supervised physical activity can reduce LDL cholesterol, although effectiveness depends on exercise characteristics, adherence, and population-specific factors. Standardized exercise protocols and further high-quality studies are needed to develop population-specific recommendations.
Co-Authors Atikah Rahayu Cerika Rismayanthi Satria Akbar Putra Asmara