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All Journal Indonesian Journal of Tropical and Infectious Disease JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Narra J
Rusli, Musofa
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

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Correlation between ESBL-Producing Bacteria Infection with Sepsis Severity of Patient in Medical Ward of Internal Medicine Department Dr. Soetomo General Hospital in 2016 Pratiwi, Asri Dhea; Rusli, Musofa; Utomo, Budi
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.452 KB) | DOI: 10.20473/juxta.V10I22019.84-87

Abstract

Introduction: Sepsis is life-threatening condition that begins with infections that trigger pro-inflammation overresponse. Delaying antibiotic treatment in sepsis can cause serious condition. In ESBL-producing bacteria, the antibiotic resistance is common and it might cause harm to sepsis patient. This research aims to analyze the correlation between infections of ESBL-producing bacteria with sepsis severity. Methods: This study was observational analytic on sepsis patient in Internal Medicine Ward of Dr. Soetomo General Hospital. The data were taken from medical records of the patient. The severity of sepsis was based on Surviving Sepsis Campaign 2012. Results: A total 72 sepsis patients were included in this study, which consist of 40 patients with non-producing ESBL GNB and 32 patients with ESBL-producing bacteria. The most common bacteria in ESBL infection is Escherichia coli ESBL+ (75%) and non ESBL infection is Acinetobacter baumanii (27.5%). Septic shock is more common in patient with ESBL-producing bacteria (53.1% vs 22.5%). The correlation between ESBL infection and sepsis severity is significant and the power of correlation is low (p = 0.048; r = 0.234). Conclusion: There is a correlation between ESBL-producing bacteria infection with sepsis severity and the power of correlation is low (p = 0.048, r = 0.234).
Mortality Profile of COVID-19 Co-Infection in HIV/AIDS Patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Januarti, Catur Ifda; Rusli, Musofa; Nugraha, Jusak; Puspitasari, Dwiyanti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.129-134

Abstract

Highlights: The majority of HIV/AIDS patients who succumbed to the effects of co-infection at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, were of productive age, with the predominant complications being anemia and bacterial infections. Tuberculosis was listed as the most common opportunistic infection that exacerbated the condition of HIV/AIDS patients and caused death during the ongoing pandemic of COVID-19.   Abstract Introduction: Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is an immune system disease caused by the HIV infection, making individuals susceptible to various diseases, including coronavirus disease (COVID-19). Co-infection in HIV/AIDS patients can worsen the severity of the diseases, especially in those with comorbidities, complications, and opportunistic infections, potentially leading to death. This study aimed to determine the mortality profile of COVID-19 co-infection in HIV/AIDS patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January 2020 to December 2022. Methods: This study employed a descriptive cross-sectional method, utilizing secondary data from 48 medical records of COVID-19 co-infection in HIV/AIDS patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January 2020 to December 2022, collected through a total sampling technique. Results: Of the 105 total HIV/AIDS patients with COVID-19 co-infection, 48 were selected in this study based on predefined inclusion and exclusion criteria. The mortality profile showed a predominance of males (75%), with an average age of 36.5 years. The most common comorbidity was bacterial infection (38.6%), with the highest complication being anemia (55.6%), and the most prevalent opportunistic infection being tuberculosis/TB (50%). Conclusion: The mortality profile of COVID-19 co-infection in HIV/AIDS patients indicated a higher occurrence among males, with an average age of 36.5 years old. The most common comorbidity was bacterial infection, whilst the most prevalent complications include anemia, with TB being the most frequent opportunistic infection.
Co-Authors Agung Dwi Wahyu Widodo Aryati Aryati Bramantono Bramantono, Bramantono Budi Utomo Dwiyanti Puspitasari, Dwiyanti Ernawati Ernawati Januarti, Catur Ifda Jusak Nugraha Pratiwi, Asri Dhea Qonitatillah, Jihan Rahayu, Dwi RP. Rizaliansyah, Ferdian Samsriyaningsih Handayani Sellynastiti, Sarah Triwinar Shabira, Naura Ghina Widyoningroem, Anita Yetti Hernaningsih