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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) The Indonesian Journal of Public Health YARSI Medical Journal Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Diptyanusa, Ajib
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Prediction model of dengue hemorrhagic fever transmission to enhance early warning system in Gergunung Village, Klaten District, Central Java Satoto, Tri Baskoro Tunggul; Dwiputro, Alfin Harjuno; Risdwiyanto, Rifa Nadhifa; Hakim, A. Ulil Fadli; Pascawati, Nur Alvira; Diptyanusa, Ajib
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 51, No 3 (2019)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (285.788 KB) | DOI: 10.19106/JMedSci005103201909

Abstract

The dengue virus that causes dengue hemorrhagic fever (DHF) in principle is transmitted to humans through the bites of Aedes sp. In Indonesia, the disease is endemic in most provinces, including in Gergunung Village in Klaten District, Central Java. The village has shown the highest incidence of DHF for the last 5 years. Changes in demographical conditions, environment, and climate condition are predictors of dengue fever. This study aimed to demonstrate the association among human behavioral variables, physical environmental factors, and climate elements with DHF transmission to develop active surveillance model of DHF outbreak by the analysis of potential predictors. The research was an observational analytic study with case control design. Study population was selected from households with DHF case in 2016 through 2017 and the controls with ratio of 1:2. In total, 34 households were labeled as case and 68 households were labeled as control. Data collection was performed by observations, direct measurements, and interviews. Data were analyzed using appropriate statistical analysis with probability value of p<0.05. The result showed that insecticide use, proper waste management, livestock breeding, presence of plastered floor, water-resistant walls, bedroom windows, doors, gutters, and open drainage system, all did not show association with DHF case occurrence (p>0.05). In contrast, houses closer to each other tended to have more DHF cases (p<0.05; OR: 2.96; 95% CI: 1.01–8.67). Physical environmental factors and climate elements did not demonstrate significant associations with DHF case occurrence in this study. Human behavioral variables, physical environmental factors, and climate elements may serve as potential predictors of DHF outbreak, hence should be put into the model to enhance early warning system.
ENVIRONMENTAL FACTORS OF THE HOME AFFECT THE DENSITY OF AEDES AEGYPTI (DIPTERA: CULICIDAE) Satoto, Tri Baskoro Tunggul; Diptyanusa, Ajib; Setiawan, Yohanes Didik; Alvira, Nur
Jurnal Kedokteran YARSI Vol 25, No 1 (2017): JANUARI - APRIL 2017
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.601 KB) | DOI: 10.33476/jky.v25i1.298

Abstract

The transmission of Dengue Hemorrhagic Fever (DHF) by Aedes aegypti and Aedes albopictus mosquitoes is influenced by climate change and several environmental factors, namely light intensity, CO2, temperature, humidity, housing condition, drainage, and vegetation. This study aims to identify the relationship between environmental factors and dengue vector population density. This research applies an observational analytic study with a cross-sectional design. The study was conducted in 2012, in the city of Yogyakarta, Indonesia, in 39 houses in the Kricak Village and in 50 houses in the Prenggan Village. Data were collected by observation, interview, and completing checklists, as well as by measuring environmental variables. The differential effect of various factors influencing mosquito density was tested using an independent sample t-test for physical environmental factors and chi-square test for the variable physical condition of the house, biologically relevant environmental factors, drainage, residential density, and the distance between houses. The probability value was p 0.05. The results showed that differences in the physical environment, the physical condition of the house, residential density, and vegetation, all affect the density of dengue vector mosquitoes in the villages of Kricak and Prenggan. The need of raising public awareness about healthy living and care for the environment, along with advocacy to stakeholders, is important for vector density control. 
TRIAL OF NEEM OIL (AZADIRACHTA INDICA) AS BASIC COMPOUND OF ELECTRIC LIQUID VAPORIZER AGAINST AEDES AEGYPTI MORTALITY Diptyanusa, Ajib; Satoto, Tri Baskoro Tunggul; Hadianto, Tridjoko
Jurnal Kedokteran YARSI Vol 25, No 1 (2017): JANUARI - APRIL 2017
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jky.v25i1.296

Abstract

Dengue Hemorrhagic Fever (DHF), commonly caused by Aedes aegypti mosquito bites, has been one of the world?s major concern for progressively increasing incidence. To prevent further increase in DHF incidence, an effective yet safe vector control method is needed. One of the most common method of vector control in Indonesia is using electric liquid vaporizer. Basic compounds which are less toxic to humans and less resistance-producing to mosquitoes are preferred, without neglecting its ability in killing mosquitoes. Neem trees (Azadirachta indica) could be easily found in many areas in Indonesia, mainly functioning as shading trees. Leaves and seed of neem tree may contain active compound used as natural insecticides, azadirachtin. The research aims to identify killing effect of neem oil as basic compound of electric liquid vaporizer against Aedes aegypti. Research subjects were 275 Aedes aegypti mosquitoes, aged 2-5 days. Subjects were divided into 3 groups: group A (negative control), group B (100% neem oil), and group C (0.001% d-allethrin as positive control). Knockdown time (KT1, KT50, KT95, KT100) and 24-hours mortality were observed. Test replications were done 3 times. The results showed that pure neem oil (Azadirachta indica) has no direct killing effect against Aedes aegypti. Further research is encouraged regarding identification of adulticide characteristics of azadirachtin and other active compounds of neem oil, such as nimbidin and nimbin.
BLASTOCYSTIS HOMINIS INFECTION IN CHILDREN WITH HIV/AIDS DURING COVID-19 RELATED DISRUPTION ERA: A CROSS-SECTIONAL STUDY Permasutha, Made Bayu; Diptyanusa, Ajib
The Indonesian Journal of Public Health Vol. 19 No. 3 (2024): THE INDONESIAN JOURNAL OF PUBLIC HEALTH
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijph.v19i3.2024.520-533

Abstract

Introduction: The coronavirus disease 2019 (COVID-19) epidemic has resulted in significant disruption to health services in multiple nations. In Indonesia, the impact occurred on changes in services for HIV/AIDS patients. As a result, there is a high rate of parasitic co-infection disease, including Blastocystis hominis. Prior research indicates that the occurrence of this illness varies greatly among individuals with HIV/AIDS, with rates ranging from 3.86% to 72.40%. Aims: The objective of this study is to ascertain the prevalence and molecular epidemiology of infection, develop a predictive model, and examine the correlation between clinical symptoms and the severity of Blastocystis results. Methods: Thirty-eight children with HIV/AIDS in Yogyakarta-Indonesia, from May until August 2021 were examined by direct examination, culture, PCR, and sequencing. In addition, a structured questionnaire was used to obtain additional data regarding baseline information and other factors influencing Blastocystis infection. The results obtained were subjected to phylogenetic, univariate and multivariate data analysis. Results: Out of the 38 samples studied, 26 (68.4%) were positive for Blastocystis. The results of sequencing demonstrated the finding of subtype 3 (ST3) and subtype 4 (ST4).  From univariate and multivariate analysis, a longer duration of therapy is a predictor of Blastocystis infection (AOR 6.54, P=0.04). The relationship between clinical manifestations and intensity of Blastocystis findings showed a non-significant association (P>0.99). Conclusion: Children with HIV/AIDS had a significantly high incidence of Blastocystis infection, potentially attributed to the interruption of services resulting from the COVID-19 pandemic.
Controlling Factors that Potentially against Transmission of Dengue Hemorrhagic Fever at State Elementary Schools in Yogyakarta Satoto, Tri Baskoro Tunggul; Alvira, Nur; Wibawa, Tri; Diptyanusa, Ajib
Kesmas Vol. 11, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sekolah dasar merupakan tempat yang dapat mengakibatkan peningkatan penyakit dengue pada anak karena faktor lingkungan, adanya potensi penularan, belum adanya system manajemen lingkungan yang baik dan beberapa upaya pengendalian yang tidak lagi efektif. Penelitian ini bertujuan untuk mengetahui faktor yang berpotensi terhadap penularan demam berdarah dengue bagi anak, sehingga sistem kewaspadaan dini dapat ditegakkan. Jenis penelitian ini adalah analitik dengan rancangan potong lintang. Penelitian dilaksanakan pada 91 sekolah dasar negeri di Kota Yogyakarta. Variabel yang diobservasi adalah serotype virus DEN, resistensi insektisida, kepadatan vektor,dan kondisi fisik sekolah. Analisis data menggunakan analisis deskriptif dan korelasi-regresi (a = 0.05). Hasil menunjukkan bahwa terdapat delapan sekolah dengan virus dengue serotip 2 and 3, terjadi resistensi insektisida organofosfat tingkat ringan dan sedang, lingkungan sekolah telah rentan terhadap penularan demam berdarah berdasarkan container index, house index, breteau index dan ovitrap index, suhu dan kelembaban di dalam dan luar ruangan berpotensi terhadap tingginya kepadatan telur, ventilasi tidak terpasang kawat kasa, dan jarak antara bangunan sangat dekat dapat menyebabkan penularan menjadi sangat cepat. Elementary school is a place that can result in increase of dengue disease among children because of environmental factors, potential transmission, the absence of good environmental management system and some control efforts which are no longer effective. This study aimed to determine factors that potentially against transmission of dengue hemorrhagic fever in state elementary school, so the early warning system can be enforced. Type of study was analytic with cross-sectional design. The study was conducted in 91 state elementary schools in Yogyakarta City in 2014. Variables in the observation are virus serotype DEN, insecticide resistance, the density of vector and physical condition of schools. Data analysis used descriptive and correlation-regression (a = 5%). Results showed that there were eight schools with dengue virus serotype 2 and 3 mosquitoes declared to have mild and moderate resistance to organophosphate, the school environment was susceptible to transmission of dengue hemorrhagic fever based on the container index, house index, breteau index and ovitrap index, temperature and humidity inside and outside were potential to the high density of eggs, wire netting was not installed on ventilation and the very close distance between the buildings could lead to transmission.
Co-Authors Dwiputro, Alfin Harjuno Hakim, A. Ulil Fadli Made Bayu Permasutha Pascawati, Nur Alvira Risdwiyanto, Rifa Nadhifa Setiawan, Yohanes Didik Tri Baskoro Tunggul Satoto Tri Wibawa Tridjoko Hadianto, Tridjoko