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All Journal Jurnal Kesehatan Lingkungan indonesia Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Nugraheni, Enny
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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ANALYSIS OF RISK FACTORS FOR DELAYED DIAGNOSIS IN PULMONARY TUBERCULOSIS CASES IN BENGKULU CITY Putri, Marissa Aurelya; Mirna; Sundari, Mulya; Nugraheni, Enny
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 11 No. 3 (2024): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v11i3.443

Abstract

This study aims to analyse the factors associated with delayed diagnosis of Pulmonary Tuberculosis and the frequency distribution of TB patients. The research method was analytic-observational with cross sectional approach. The research sample was patients in Bengkulu City total of 64 respondents. The results of the analysis showed that the majority of TB patients were male, age group 16-25 years, people who had jobs, and secondary education, had initial symptoms of cough, lived in the central area of the city, the distance from home to the nearest health facility was 1 < 2 km, had a good level of knowledge, the majority had low stigma towards TB disease. There was no significant association between delay in diagnosis and gender, age, education, income, occupation, distance from home to health centre, location of residence, initial symptoms, first action of health centre, first health service visited. There was a significant association between the time between initial symptoms and seeking treatment and the incidence of delayed diagnosis. However, there was no significant association between delayed diagnosis, patient stigma about TB disease and knowledge.
Edukasi Perilaku Hidup Bersih dan Sehat untuk Pencegahan Penyakit Infeksi Kulit Rizqoh, Debie; Nugraheni, Enny; Prihatiningrum, Atik; Meidiyanti, Prima
DHARMA RAFLESIA Vol 22 No 2 (2024): DESEMBER (ACCREDITED SINTA 5)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/dr.v22i2.37797

Abstract

Penyakit kulit sering ditemukan pada masyarakat yang kurang memperhatikan personal hygiene dan sanitasi lingkungan. Beberapa jenis penyakit yang sering dialami masyarakat yaitu psoriasis, kusta atau hansen, dermatitis, scabies, panu, cacar, dan lain-lain. Kebersihan kulit, tangan, kuku dan kebersihan handuk paling banyak masuk dalam kategori buruk. Kebersihan kulit, tangan, kuku, pakaian, handuk, tempat tidur, sprei, dan sanitasi lingkungan memiliki korelasi yang signifikan dengan keluhan penyakit kulit. Perilaku hidup bersih dan sehat (PHBS) merupakan salah satu strategi untuk menanggulangi masalah penyakit infeksi kulit. Kegiatan pengabdian kepada masyarakat ini telah dilaksanakan di Desa Sri Kuncoro, Kecamatan Pondok Kelapa, Kabupaten Bengkulu Tengah. Kegiatan dilaksanakan pada tanggal 28 Agustus 2024. Sebelum kegiatan tersebut, tim pengabdian menyusun buku edukasi dan poster edukasi yang dibagikan pada saat kegiatan penyuluhan. Pada saat kegiatan pengabdian, ada dua materi yang disampaikan yaitu materi “Penyakit Infeksi pada Kulit” dan “Pencegahan Penyakit Infeksi Kulit”. Selain itu, dilakukan pre-test dan post-test untuk mengevaluasi pengetahuan peserta. Terjadi peningkatan pengetahuan peserta setelah mengikuti kegiatan pengabdian.
Analisis Spasio-Temporal Kondisi Iklim dan Jumlah Kejadian Demam Berdarah Dengue (DBD) Tahun 2012-2021 di Bengkulu Khairinnisa, Khairinnisa; Fauzi, Yulian; Nugraheni, Enny
Jurnal Kesehatan Lingkungan Indonesia Vol 24, No 2 (2025): Juni 2025
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.67945

Abstract

Latar belakang: Infeksi virus dengue dapat menyebabkan Penyakit Demam Berdarah Dengue (DBD). Virus tersebut ditransmisikan melalui gigitan nyamuk Aedes sebagai vektor penting. Faktor perubahan cuaca, seperti curah hujan dan temperatur, memiliki dampak padapenyebaran DBD. Studi ini bertujuan untuk memberikan pemahaman yang lebih komprehensif mengenai dinamika DBD di Provinsi Bengkulu serta hubungannya dengan kondisi iklim, sehingga dapat mendukung pengembangan strategi terkait pencegahan dan pengendalian yang adaptif terhadap perubahan iklim.Metode: Pendekatan observasional analitik dan desain studi ekologi time series study digunakan untuk mengetahui hubungan antar variabel kondisi iklim dengan persebaran jumlah kasus DBD di Provinsi Bengkulu dengan uji korelasi Pearson.Hasil: Hasil uji menunjukkan bahwa variabel curah hujan, kelembapan udara, temperatur udara, dan kecepatan angin tidak ada hubungan yang signifikan terhadap jumlah kasus DBD di Provinsi Bengkulu tahun 2012-2021. Semua variabel menunjukkan koefisien korelasi (r) mendekati nol, dan nilai probabilitas (p) melebihi tingkat signifikansi (p=0,05). Namun, di beberapa kabupaten menunjukkan adanya hubungan yang signifikan antara curah hujan, suhu udara dan kecepatan angin dengan jumlah kasus DBD.Simpulan: variabel kondisi iklim pada studi ini yaitu curah hujan, kelembapan udara, temperatur udara, dan kecepatan angin, menunjukkan tidak terdapat hubungan yang signifikan dengan jumlah kasus DBD. Meskipun demikian, beberapa wilayah menunjukkan ada hubungan signifikan dengan curah hujan dan temperatur udara. ABSTRACT Title:  Spatial-Temporal Analysis of Relationship Between Climate Conditions and Dengue Hemorrhagic Fever (DHF) in 2012-2021 in BengkuluBackground: Dengue Hemorrhagic Fever or DHF is caused by Dengue virus (DENV) infection transmitted through the bite of Aedes mosquitoes, main vector. Climate change factors, like rainfall and temperature, impact the spread of infeksi dengue.Method: This research aims to provide a comprehensive study of DHF dynamics in Bengkulu Province and its correlation with climate conditions, supporting the development of adaptive prevention and control strategies against climate change. This study employs an observational analytical approach and a time series ecological study design to explore the relationship between climate variables and the distribution of DHF cases in Bengkulu Province, using Pearson correlation analysis.Result: The results indicate that rainfall, air humidity, air temperature, and wind speed variables do not significantly correlate with the number of DHF cases in Bengkulu Province from 2012 to 2021. All variables show correlation coefficients (r) close to zero, and the probability values (p) exceed the significance level (p=0.05). However, in some districts, there is a significant relationship between rainfall, air temperature, and wind speed with the number of DHF cases.Conclusion: Several areas show that the incidence of dengue hemorrhagic fever is related to rainfall and air temperature
CERVICITIS CHRONIC ET CAUSA TUBERCULOUS: A CASE REPORT Siregar, Maurizka Juwita; Djais, Taufik Hidayat; Nugraheni, Enny
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 3 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i3.697

Abstract

Tuberculous cervicitis is a rare form of genital tuberculosis that often mimics cervical cancer due to similar symptoms, such as abnormal vaginal bleeding and vaginal discharge. Early detection is crucial to prevent misdiagnosis and mistreatment. A 37-year-old woman presented with six months of vaginal bleeding, postcoital bleeding, and recent  vaginal discharge. Physical examination revealed an irregular cervical lesion, but laboratory and imaging findings were inconclusive. A conization biopsy revealed granulomatous inflammation with caseous necrosis, confirming tuberculous cervicitis. Acid-fast bacillus staining was negative. The patient was treated with standard antituberculous regimen, resulting in symptom resolution and clinical impprovement. Tuberculous cervicitis is often missed due to its rarity and malignancy-like symptoms. Diagnosis relies on histopathology, as microbiological confirmation is difficult. Prompt antituberculous treatment prevents serious complications. Surgical intervention may be necessary for both diagnosis and treatment.  Conclusion: Tuberculous cervicitis should be considered in cases of chronic cervicitis, especially in endemic areas. Timely diagnosis and treatment promote a good prognosis and prevent unnecessary invasive procedures.
Immunopathogenesis of dengue virus and Salmonella typhi coinfection Nugraheni, Enny; Sudiro, Tjahjani Mirawati; Nainggolan, Leonard; Fithriyah; Dewi, Beti Ernawati
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 2, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss2.art12

Abstract

Typhoid, malaria, leptospirosis, dengue virus (DENV), and other arboviruses are endemic in Indonesia. Therefore, it is more likely that DENV and other infectious diseases could be coinfected. More severe symptoms, delayed identification, and ineffective treatment of the illness can all result from Salmonella typhi coinfection. To serve as a principle for clinicians’ considerations while diagnosing and prescribing, we aim to examine the immunopathogenesis of dengue associated with Salmonella typhi coinfection. Dengue virus has the potential to increase both susceptibility and incidence of this coinfection, leading to dengue haemorrhagic fever (DHF) with more severe clinical symptoms. This is explained by regulating impact of coinfection in the presence of gram-negative membrane endotoxin, DENV replication, and lipopolysaccharide (LPS). If Salmonella typhi coinfection is not treated promptly, both dengue and Salmonella typhi can affect several organs and result in significant morbidity and death. Dengue and typhoid immunopathogenesis coinfection are unclear. When dengue monoinfection compared with Salmonella dengue dual infections are related to higher fatality and morbidity rates.
Co-Authors Atik Prihatiningrum, Atik Beti Ernawati Dewi Debie Rizqoh Djais, Taufik Hidayat Fithriyah Khairinnisa, Khairinnisa Leonard Nainggolan Meidiyanti, Prima Mirna Putri, Marissa Aurelya Siregar, Maurizka Juwita Sundari, Mulya TJAHJANI MIRAWATI SUDIRO Yulian Fauzi