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All Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Faizah Ariqoh Nariswari
Universitas Duta Bangsa Surakarta
Health Professions Nursing Public Health

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Uji Efektivitas Nanoemulsi Ekstrak Daun Melinjo (Gnetum gnemon L.) Sebagai Tabir Surya dengan Metode Spektrofotometri UV-Vis Faizah Ariqoh Nariswari; Tatiana Siska Wardani; Tiara Ajeng Listyani
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 6 (2026): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i6.2584

Abstract

Excessive ultraviolet (UV) exposure can cause skin damage, including melanoma. In 2020, the World Health Organization reported 1,609 melanoma cases in Indonesia with 699 deaths. Melinjo leaves (Gnetum gnemon L.) contain flavonoids, tannins, saponins, and phenolic compounds with antioxidant and photoprotective potential. This study aimed to evaluate the sunscreen activity of melinjo leaf extract, its formulation into nanoemulsions, and the highest Sun Protection Factor (SPF) achieved. Methods: Extracts were standardized and formulated into nanoemulsions with concentrations of 0.20% (F1), 0.25% (F2), and 0.30% (F3). Physical properties including particle size, transmittance, pH, viscosity, emulsion type, irritation, and hedonic characteristics were assessed. Sunscreen efficacy was tested in vitro using UV-Vis spectrophotometry (290–320 nm), and SPF values were calculated with the Mansur equation. Results: Extract concentrations of 100–300 ppm produced SPF values of 5.07–9.97. Nanoemulsions F0–F3 showed SPF values of 4.67–13.93, with all formulations meeting quality standards. Conclusion: Melinjo leaf extract demonstrated sunscreen activity and was successfully formulated into nanoemulsions. The highest protection was observed in F3, with an SPF of 13.93, categorized as maximum protection.
Co-Authors Listyani, Tiara Ajeng Tatiana Siska Wardani