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All Journal e-GIGI Dentika Dental Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Journal of Applied Nursing and Health Odonto dental journal
Lesmana, Dian
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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SALIVA AS A POTENTIAL DIAGNOSTIC OF BIOMARKER OF ORAL AND SYSTEMIC DISEASES: SALIVA SEBAGAI BIOMARKER POTENSIAL DIAGNOSTIK PENYAKIT RONGGA MULUT DAN SISTEMIK Lesmana, Dian; Tjahajawati, Sri; Lubis, Vita Tarawan
Dentika: Dental Journal Vol. 19 No. 2 (2016): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (407.178 KB) | DOI: 10.32734/dentika.v19i2.460

Abstract

Saliva is a biological fluid that is secreted by the major, minor and other accessories salivary glands. Saliva has a high potential as an indicator that reflects the health of our body. Saliva also plays an important role as a protector, lubricate oral structure with mucin, set a neutral pH through the buffer capacity, clean the oral cavity, stimulate wound healing, help the taste buds in the taste of food, facilitate the process of chewing food, form a bolus and make it easier swallowing, and minimize food particles through the activity of the enzyme amylase and lipase. The use of saliva as a biomarker in diagnosing provide more advantages than the serum and other body fluids due to using non-invasive techniques, cost-efficient, as well as methods for collecting samples for disease screening without the need to train professional personnel. The benefits derived from the saliva as a biomarker are early detection and screening of disease to the development of caries, periodontal disease, tumors and malignancy, hereditary, wound healing, autoimmune disease, infectious diseases, cardiovascular diseases, drug monitoring, forensic, and the psychological influence. At this time, the function of saliva as a diagnostic biomarker is not widely known, therefore the development of salivary further enhance because it can produce functional similarities with serum and reflect the body's physiological status in the oral cavity and systemic disease.
Penilaian kualitas hidup pasien abses periapikal studi menggunakan WHOQOL-BREF: observasional deskriptif Millenia Pentury, Peggy Adriella; Santoso, Ivana Abigayl; Lesmana, Dian; Utami, Nikita Irzana; Ma'rup, Fathul Mauludy; Gempita, Enamorado Dara; Pradana, Tio
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 36, No 2 (2024): Agustus 2024
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v36i2.55316

Abstract

ABSTRAKPendahuluan: Abses periapikal menyebabkan gigi berlubang mengalami infeksi, biasanya akibat karies gigi, trauma, atau kegagalan perawatan saluran akar gigi. Kualitas hidup merujuk pada kesejahteraan individu terkait Kesehatan secara holistik. Kondisi abses periapikal dapat memengaruhi fungsi keseharian individu termasuk fisik, psikologis, dan sosial. Tujuan penelitian yaitu menilai kualitas hidup pasien abses periapikal menggunakan kuesioner World Health Organization-BREF (WHOQOL-BREF) di BLUD UPTD Puskesmas Pataruman 3 Kota Banjar. Metode: Penelitian observasional deskriptif dilakukan pada 37 subyek menggunakan rumus slovin, teknik pengambilan sampel non-probability, accidental sampling. Kriteria inklusi yaitu pasien yang didiagnosis abses periapikal, berusia 17 tahun ke atas, dan dapat berkomunikasi dengan efektif. Kriteria eksklusi meliputi pasien yang menolak untuk berpartisipasi atau tidak memberikan informed consent, individu yang mengisi kurang dari 20% dari kuesioner, dan individu dengan kondisi medis yang serius yang dapat memengaruhi kualitas hidup secara signifikan. Penilaian kualitas hidup dinilai dengan menggunakan kuesioner WHOQOL-BREF yang memiliki 5 skala respon, yaitu sangat buruk, buruk, cukup, baik, dan sangat baik. Hasil: Kualitas hidup pasien abses periapikal di BLUD UPTD Puskesmas Pataruman 3 Kota Banjar, masuk dalam kategori: baik (8,11%), cukup (29,72%), dan buruk (62,16%). Domain kesehatan fisik dan hubungan sosial adalah domain yang paling sering dilaporkan sebagai cukup. Simpulan: Kualitas hidup pasien abses periapikal pada domain 1, 2, 3, dan 4 berada pada rentang skor rentang cukup buruk sampai baik. Namun apabila dilihat secara spesifik pada domain 1 (kesehatan fisik) dan domain 3 (hubungan sosial) berada pada rentang skor cukup buruk. Assessment of the quality of life of patients with periapical abscess: a study using whoqol-bref study: descriptive observational  Introduction: A periapical abscess causes infection in decayed teeth, usually resulting from dental caries, trauma, or failure root canal treatment. Quality of life encompasses the physical, psychological, and social well-being of individuals, which can be significantly impacted by periapical abscess. This study aims to assess the quality of life of periapical abscess patients using the World Health Organization-BREF (WHOQOL-BREF) questionnaire at the BLUD UPTD Pataruman 3 Health Center, Banjar City. Methods: This descriptive observational study included 37 subjects, selected using Slovin’s formula and non-probability accidental sampling. The inclusion criteria were patients diagnosed with periapical abscess, aged 17 years or older, and able to communicate effectively. Exclusion criteria included patients who refused to participate or did not provide informed consent, individuals who completed less than 20% of questionnaire, and those with serious medical conditions that could significantly affect their quality of life. Quality of life was assessed using the WHOQOL-BREF questionnaire, which uses a 5-point response scale: very poor, poor, fair, good, and very good. Results: The quality of life of periapical abscesses patients at BLUD UPTD Puskesmas Pataruman 3, Banjar City, was categorized as good (8.11%), fair (29.72%), and poor (62.16%). The physical health and social relationships domains were most frequently reported as fair. Conclusion: The quality of life of periapical abscess patients across domains 1, 2, 3, and 4 ranged from poor to good. However, when examined specifically, domain 1 (physical health) and domain 3 (social relationship) fell within the range of fair to poor.
The difference of blood pressure before and after consuming Green Kiwi (Actinidia deliciosa) in the young adult group Lesmana, Dian; Rizali, Ervin; Kintawati, Silvi
Padjadjaran Journal of Dentistry Vol 25, No 3 (2013): November 2013
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol25no3.26808

Abstract

Introduction: Green Kiwi fruit (Actinidia deliciosa) has a lot of nutritional content, one of them is potassium. Potassium helps maintain osmotic pressure in intracellular fluid, protect body’s electrolyte balance, regulate heartbeat, maintain muscle and nerve cell function, reduce the risk of stroke and heart disesase, and decrease blood pressure. Methods: This study is an experimental research, using pair t-test measurement to analize the difference of blood pressure before and after consuming Green Kiwi fruit (Actinidia deliciosa) in early adulthod. The sample are thirty five students of Faculty of Dentistry, Padjadjaran. The number of green kiwi fruit is consume as much as 1 fruits or 150 grams. Blood pressure measured by sphygmomanometer with auscultatory-palpation method. Results: The result of this study shows the averaged blood pressure before and after consuming green kiwi fruit Is 99,543/68,438 mmHg and 97,581/66,743mmHg. Conclusion: The conclusion of the study indicates the existence of difference in blood pressure before and after consuming Green Kiwi fruit (Actinidia deliciosa) in early adulthood (p<5%).
THE DESCRIPTION OF PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOR DURING COVID-19 PANDEMIC ON “X” UNIVERSITY’s STUDENTS Lesmana, Dian; Setiawan, Ignatius; Aswada, Dionisia Vinda
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (375.282 KB) | DOI: 10.30659/odj.9.1.21-27

Abstract

Background: As of 9th March 2020, World Health Organization declared the outbreak of COVID-19 as a pandemic. The government takes a policy to implement social restrictions aim to restrict COVID-19. The restrictions includes restricted social gatherings, public facilities and closed the schools, so the student can only do learn and their activities from home. This pandemic also affected daily life with physical activity will be impaired and increased sedentary behavior. Method: A descriptive study with cross-sectional design to describe the physical activity and sedentary behavior on university student during the COVID-19 pandemic. Physical activity and sedentary behavior was assessed using Global Physical Activity Questionnaire (GPAQ). The participant of this study were taken using stratified random sampling, and consisted of 297 students drawn proportionally from 9 faculties.Result: The results showed that 129 students (43,4%) included in moderate physical activity category, 92 students (31%) included in low category, and 76 students (25,6%) included in high category. Overall, the average of GPAQ score of 2347 METs per week indicates that students’ physical activity is in moderate category. Male students were more physically active (3448.9METs) than female (1778.6 METs). The study also determine that most of the student had sedentary behavior by sitting or lying down about 327,9 minutes per day.Conclusion: The conclusion is students of different faculties had different physical activity level during this pandemic. Most of the students is in moderate physical activity category and high sedentary behavior.
Effect of Black Cumin Extract (Nigella sativa Linn.) on Closure Time of Incision Wound in Swiss Webster Mice Febrianto, Verent; Bulan, Susanti; Lesmana, Dian
e-GiGi Vol. 10 No. 1 (2022): e-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.v10i1.39156

Abstract

Abstract: Incision wounds in dentistry can be caused by several procedures inter alia incision of abscess, odontectomy, extraoral incision, parotidectomy, and others. Certain drugs are needed to accelerate wound healing and prevent infection. Generally, anti-inflammatory drugs such as steroids and non-steroids are given to accelerate wound healing. Herbal remedies such as black cumin extract can also be an alternative to be applied topically.  This study aimed to evaluate the effect of black cumin extract on closure time of incision wound on the back of male Swiss Webster mice. This was a laboratory and experimental study. Subjects were 36 Swiss Webster mice divided into two groups. Incision wounds were performed on the back of each subjects. Group I was not given any treatment meanwhile group II was treated with topical application of black cumin extract. The Mann Whitney test showed that the mean wound closure time of group II was 9.7 days, meanwhile of group I was 12.7 days (p=0.0000855). In conclusion, there was a significant effect of black cumin extract on the closure time of the incision wound on the back of Swiss Webster mice which resulted in the fastest complete wound closure on the 8th day.Keywords:  black cumin extract; wound closure time Abstrak: Luka insisi dalam bidang kedokteran gigi dapat disebabkan oleh berbagai prosedur, seperti insisi abses, odontektomi, insisi ekstraoral, parotidektomi, dan sebagainya. Pemberian obat diperlukan untuk mempercepat penyembuhan luka dan mencegah terjadinya infeksi. Umumnya, obat anti-inflamasi seperti steroid maupun nonsteroid dapat diberikan untuk mempercepat penyembuhan luka. Obat herbal seperti ekstrak jintan hitam dapat menjadi alternatif yang diaplikasikan secara topikal. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak jintan hitam terhadap waktu penutupan luka insisi pada punggung mencit Swiss Webster jantan. Jenis penelitian ialah eksperimental laboratorik. Subyek penelitian berjumlah 36 ekor mencit Swiss Webster jantan yang dibagi menjadi dua kelompok. Semua subyek dibuat luka insisi pada punggung. Kelompok I tidak diberikan perlakuan sedangkan kelompok II diberi perlakuan aplikasi ekstrak jintan hitam secara topikal. Hasil uji Mann-Whitney menunjukkan rerata waktu penutupan luka insisi kelompok II ialah 9,7 hari, sedangkan pada kelompok I 12,7 hari (nilai p=0,0000855). Simpulan penelitian ini ialah terdapat pengaruh bermakna dari ekstrak jintan hitam terhadap waktu penutupan luka insisi pada punggung mencit Swiss Webster yaitu terjadi penutupan luka sempurna paling cepat pada hari ke-8.Kata kunci: ekstrak jintan hitam; waktu pentupan luka
Effect of Postoperative Methylprednisolone on Swelling and Pain After Mandibular Third Molar Surgery: A Randomized Controlled Trial Tanumiharja, Leonardo Jaya Setiadi; Situmorang, Gabriella Debora Alvionita; Sumaji, Borman; Lesmana, Dian
Journal of Applied Nursing and Health Vol. 8 No. 1 (2026): Journal of Applied Nursing and Health
Publisher : Chakra Brahmanda Lentera Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55018/janh.v8i1.483

Abstract

Background: Pain and swelling are common inflammatory complications following mandibular third molar surgery. Corticosteroids are widely used to control postoperative inflammation and improve patient comfort. However, evidence regarding the effectiveness of low-dose postoperative methylprednisolone, particularly at an 8 mg dose, remains limited, especially in low- and middle-income countries (LMICs). This study aimed to evaluate the effectiveness of an 8 mg dose of methylprednisolone on postoperative pain intensity and facial swelling following surgery. Methods: This study employed a parallel-group, two-arm randomized controlled trial design conducted in accordance with the CONSORT guidelines. A total of 30 patients who met the inclusion criteria were randomly assigned to either the intervention group (8 mg methylprednisolone) or the control group (standard care), with 15 participants in each group. The independent variable was methylprednisolone administration, while the dependent variables included pain intensity measured using the Visual Analog Scale (VAS) and facial swelling. Outcome assessments were performed on postoperative days 1, 3, and 7. Statistical analyses were used for independent t-tests. Results: Pain intensity was lower in the methylprednisolone group than in the control group at all postoperative time points, with large between-group effect sizes observed on day 1 (p = 0.003; Cohen’s d = 1.42), day 3 (p = 0.020; Cohen’s d = 1.36), and day 7 (p = 0.007; Cohen’s d = 1.18). Facial swelling also differed between groups, showing a lower degree of swelling in the methylprednisolone group during postoperative days 1–3 (p = 0.029; Cohen’s d = 0.98) and days 3–7 (p = 0.002; Cohen’s d = 0.87), indicating consistently large effects across outcomes. Conclusion: Low-dose methylprednisolone is statistically and clinically effective in reducing postoperative pain and swelling following surgery and may be integrated as a safe and cost-effective adjuvant therapy in postoperative dental care.
Co-Authors Aswada, Dionisia Vinda Febrianto, Verent Gempita, Enamorado Dara Ignatius Setiawan, Ignatius Lubis, Vita Tarawan Ma'rup, Fathul Mauludy Millenia Pentury, Peggy Adriella Pradana, Tio Rizali, Ervin Rumini - Santoso, Ivana Abigayl Silvi Kintawati Situmorang, Gabriella Debora Alvionita Sri Tjahajawati, Sri Sumaji, Borman Susanti Bulan, Susanti Tanumiharja, Leonardo Jaya Setiadi Utami, Nikita Irzana