Article Per Year (5 Year)
p-Index From 2021 - 2026
0.817
P-Index
This Author published in this journals
All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Journal of Dentomaxillofacial Science Jurnal Material Kedokteran Gigi Jurnal Layanan Masyarakat (Journal of Public Service)
Devi Rianti
Departemen Material Kedokteran Gigi Fakultas Kedokteran Gigi Universitas Airlangga
Humanities Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Materials Science & Nanotechnology Social Sciences Other

Published : 14 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 14 Documents
Search

 1   2 
Uji Sitotoksisitas Seng Oksida Ekstrak Allium Sativum Linn. terhadap Sel Fibroblas Gingiva Manusia Nisrina Qurrota Aini; Titien Hary Agustantina; Devi Rianti
Jurnal Material Kedokteran Gigi Vol 7 No 2 (2018): JMKG Vol 7 No 2 September 2018
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.857 KB) | DOI: 10.32793/jmkg.v7i2.374

Abstract

The use of zinc oxide eugenol in open pulps is controversial because of the cytotoxic effects of eugenol. Previous research has proven that zinc oxide Allium sativum Linn. extract can be an alternative for pulp capping material because it has antibacterial effect. The materials that applied to the oral cavity must be non-cytotoxic and biocompatible, therefore cytotoxicity testing is required of zinc oxide Allium sativum Linn. extract on human gingival fibroblast cell. To determine the cytotoxicity of zinc oxide Allium sativum Linn. extract on human gingival fibroblast cell. Cytotoxicity test of a mixture of zinc oxide with Allium sativum Linn. extract using ratio 1:1 (group A) and 2:1 (group B), zinc oxide eugenol 1:2 (control group C). Each material is exposed to the human gingival fibroblast cells. The cytotoxicity test was tested using an MTT essay test. The density of optic formazan indicated the number of living cell. Cytotoxicity parameters using IC50. Data were analyzed using one-way Anova test and Tukey HSD test. The number of living cells in group A= 40,400 %, group B= 50,613 % and group C= 51,247 %. There was no significant difference between zinc oxide Allium sativum Linn at a ratio of 2:1 (group B) with zinc oxide eugenol 2:1 (group C). Zinc oxide Allium sativum Linn. extract with a ratio 2:1 were not cytotoxic toward human gingival fibroblast cell.
Uji Sitotoksitas Rebusan Buah Lerak (Sapindus rarak DC) Terhadap Sel BHK-21 Atika Rahmadina; Devi Rianti; Asti Meizarini
Jurnal Material Kedokteran Gigi Vol 4 No 1 (2015): JMKG Vol 4 No 1 Maret 2015
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.648 KB)

Abstract

Nowadays traditional herbs are become very popular in the medicine world, and also in dentistry. Lerak fruit (Sapindus rarak DC) is one of herbs which is used as a traditional detergent from long time ago. The latest research shows that right now Sapindus rarak DC infusum could be used for an alternative foaming agent as a detergent in tooth paste because of its active substance content that is Saponin. As one of dental health product, this Sapindus rarak DC infusum must be accompanied by non-toxic characteristic before it distributed in the community. The aim of this research is to find out the cytotoxicity of Sapindus rarak DC infusum to BHK-21 cells using MTT assay. This research using post test only control group design. Each group consist of 7 replications in the 96 well microplate. Cultur cells of BHK-21 prepared in media, were divided into 4 group of well. Add 50 µl of Sapindus rarak DC infusum 0,625%; 1,25%; 2,5%; 5% along with BHK-21 cells. Stored the microplate into an incubator for 24 hours. Measurement of cytotoxicity was an optical density or absorbent and read with ELISA reader 620 nm. Value of absorbent in microplate showed the number of living cells in media culture. The increasing concentration of Sapindus rarak DC infusum i.e. 0,625%; 1,25%; 2,5%; 5% would increase the death cells which that means increasing toxicity. The lowest concentration of Sapindus rarak DC infusum has the lowest cytotoxicity potential toward BHK-21 cells using MTT assay. The minimum concentration of Sapindus rarak DC infusum which could be used as an alternative foaming agent in toothpaste and not toxic is 1,25%.
Characterization nanosuspension formulated with Graptophyllum pictum (L.) Griff extract and hydroxyapatite as bone graft material: experimental laboratory study Bilbalqish, Kavanila; Rianti, Devi; Sitalaksmi, Ratri Maya; Shariff, Khairul Anuar bin
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 1 (2025): April 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i1.59462

Abstract

ABSTRACT Introduction: Hydroxyapatite is a major component of the inorganic minerals in the hard tissues of humans and has been widely used as a biomedical ceramic material in orthopedic and dentistry applications. Adding natural ingredients such as Graptophyllum pictum can increase the anti-inflammatory properties due to the presence of phenolic compounds and alkaloids. The aim of this study was to determine the characterization nanosuspension formulated with Graptophyllum pictum (L.) Griff extract and hydroxyapatite. Methods: Nanosuspension were characterized using Scanning Electron Microscopy (SEM), Electron Dispersive X-ray analysis (EDX), Fourier Transform Infrared Spectroscopy (FTIR), and Liquid Chromatography Mass Spectrometry (LCMS). These evaluations were to reveal the surface morphology, elemental composition, functional groups, and identify the active metabolite of the nanosuspension. Results: SEM revealed the morphology agglomeration of spherical hydroxyapatite particles. The EDX analysis revealed a content of carbon, oxygen, sodium, phosphorus, chlorine, potassium, and calcium with Ca/P ratio 1.47. The FTIR analysis identified hydroxyl, water molecules, carbonate, carbonyl, and phosphate groups in the sample. LC-MS analysis identified 49 active metabolites such as phenols, alkaloid, fatty acids and their derivatives, amino acids, carbohydrates, carboxylic acids, alcohols, and ketones from the sample. Conclusion: The characteristics of nanosuspension formulated with Graptophyllum pictum (L.) Griff extract and hydroxyapatite are similar to those of natural bones. Keywordscharacterization, Graptophyllum pictum, hydroxyapatite, nanosuspension Karakterisasi nano suspensi ekstrak Graptophyllum pictum (L.) Griff dan hidroksiapatit sebagai material bone graft: penelitian eksperimental laboratoris ABSTRAK Pendahuluan: Hidroksiapatit merupakan komponen utama mineral anorganik pada jaringan keras manusia dan telah banyak digunakan sebagai keramik di bidang biomedis ortopedi dan kedokteran gigi. Penambahan bahan alami seperti Graptophyllum pictum dapat meningkatkan sifat antiinflamasi karena adanya senyawa fenolik dan alkaloid. Tujuan penelitian ini adalah mengetahui karakterisasi nanosuspensi yang diformulasikan dengan ekstrak Graptophyllum pictum (L.) Griff dan hidroksiapatit. Metode: Nanosuspensi dikarakterisasi menggunakan Scanning Electron Microscopy (SEM), Electron Dispersive X-ray analysis (EDX), Fourier Transform Independent Spectroskopi (FTIR), dan Liquid Chromatography Mass Spectrometry (LCMS). Evaluasi ini dilakukan untuk menunjukkan morfologi permukaan, komposisi unsur, gugus fungsi, dan mengidentifikasi metabolit aktif nanosuspensi. Hasil: SEM menunjukkan aglomerasi morfologi partikel hidroksiapatit berbentuk bulat. Analisis EDX menunjukkan kandungan karbon, oksigen, natrium, fosfor, klorin, kalium, dan kalsium dengan rasio Ca/P 1,47. Analisis FTIR mengidentifikasi gugus hidroksil, molekul air, karbonat, karbonil, dan fosfat dalam sampel. Analisis LC-MS mengidentifikasi 49 metabolit aktif seperti fenol, alkaloid, asam lemak dan turunannya, asam amino, karbohidrat, asam karboksilat, alkohol, dan keton dari sampel. Simpulan: Karakteristik nanosuspensi yang diformulasikan dengan ekstrak Graptophyllum pictum (L.) Griff dan hidroksiapatit mirip dengan tulang alami. Kata kuncikarakterisasi, Graptophyllum pictum, hidroksiapatit, nanosuspensi
The compressive strength and static biodegradation rate of chitosan-gelatin limestone-based carbonate hydroxyapatite composite scaffold Rianti, Devi; Purnamasari, Alqomariyah Eka; Putri, Rifayinqa Ruyani; Salsabilla, Noor Zain; Faradillah; Munadziroh, Elly; Agustantina, Titien Hary; Meizarini, Asti; Yuliati, Anita; Syahrom, Ardiyansyah
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p160-165

Abstract

Background: One of the main components in tissue engineering is the scaffold, which may serve as a medium to support cell and tissue growth. Scaffolds must have good compressive strength and controlled biodegradability to show biological activities while treating bone defects. This study uses Chitosan-gelatin (C–G) with good flexibility and elasticity and high-strength carbonate hydroxyapatite (CHA), which may be the ideal scaffold for tissue engineering. Purpose: To analyze the compressive strength and static biodegradation rate within various ratios of C–G and CHA (C–G:CHA) scaffold as a requirement for bone tissue engineering. Methods: The scaffold is synthesized from C–G:CHA with three ratio variations, which are 40:60, 30:70, and 20:80 (weight for weight [w/w]), made with a freeze-drying method. The compressive strengths are then tested. The biodegradation rate is tested by soaking the scaffold in simulated body fluid for 1, 3, 7, 14, and 21 days. Data are analyzed with a one-way ANOVA parametric test. Results: The compressive strength of each ratio of C–G:CHA scaffold 40:60 (w/w), 30:70 (w/w), and 20:80 (w/w), consecutively, are 4.2 Megapascals (MPa), 3.3 MPa, 2.2 MPa, and there are no significant differences with the p= 0.069 (p>0.05). The static biodegradation percentage after 21 days on each ratio variation of C–G:CHA scaffold 40:60 (w/w), 30:70 (w/w), and 20:80 (w/w) is 25.98%, 24.67%, and 20.64%. One-way ANOVA Welch test shows the result of the p-value as p<0.05. Conclusion: The compressive strength and static biodegradation of the C–G:CHA scaffold with ratio variations of 40:60 (w/w), 30:70 (w/w), and 20:80(w/w) fulfilled the requirements as a scaffold for bone tissue engineering.
Co-Authors Amelia Hartanto Anita Yuliati Asti Meizarini Atika Rahmadina Bilbalqish, Kavanila Dimas Rudianto Fardha Elly Munadziroh Faradillah Intan Fajrin Arsyada Mahela Sefrian Luthfimaidah Nisrina Qurrota Aini Pambudi Santoso T Purnamasari, Alqomariyah Eka Putri, Rifayinqa Ruyani Ratri Maya Sitalaksmi Rini Devijanti Ridwan Salsabilla, Noor Zain Shariff, Khairul Anuar bin Soraya Dian Permata Rezky Sri Yogyarti Sugandi Mastia Anugrah Syahrom, Ardiyansyah Titien Hary Agustantina