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All Journal PAUD Teratai Juring (Journal for Research in Mathematics Learning) Wiralodra English Journal (WEJ) International Journal of English Education and Linguistics (IJoEEL) Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Simki Pedagogia Tamaddun
FATMAWATI, RIRIN
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Humanities Education Health Professions Languange, Linguistic, Communication & Media Mathematics Public Health Social Sciences Other

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Journal : Medicra (Journal of Medical Laboratory Science/Technology)

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Toxicity Test of Ethanol Extract Lempuyang Gajah (Zingiber Zerumbet (L.) Roscoe Ex Sm.) on Bilirubin and Alkaline Phosphatase Levels in Mice (Mus Musculus): Uji Toksisitas Ekstrak Etanol Lempuyang Gajah (Zingiber zerumbet (L.) Roscoe ex Sm.) Terhadap Kadar Bilirubin dan Alkalin Fosfatase pada Mencit (Mus musculus) Fatmawati, Ririn; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 2 (2022): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i2.1657

Abstract

The lempuyang gajah plant (Zingiber zerumbet (L.) Roscoe ex Sm.) is a plant that is widely used as a treatment for desease. The purpose of this study was to determine the toxic effect of the ethanol extract of lempuyang gajah (Zingiber zerumbet (L.) Roscoe ex Sm.) on levels of bilirubin and alkaline phosphatase (ALP) in the liver of mice (Mus musculus). The type of research used is descriptive quantitative with laboratory experimental methods. The mice were divided into 5 groups including normal control, negative control, dose of 4000 kg-1, 5000 kg-1 and 6000 kg-1. then observed the toxic symptoms, macroscopic, levels of bilirubin and alkaline phosphatase. The results of the phytochemical test showed that there were compounds of alkaloids, flavonoids, saponins, phenolics, steroids, triterpenoids and tannins. The results of macroscopic observations showed that the liver was still in a normal condition. The results of the One Way Anova test on bilirubin and alkaline phosphatase levels did not show any significant effect (p>0,05) influence between the normal control group, negative control, doses of 4000 kg-1, 5000 kg-1 and 6000 kg-1, so it can be said that all experimental animals had the same condition.
Co-Authors Agustin, Lilis Humairoh, Intan islam, muhammad hifdzil Jamilatur Rohmah Nelson, Zulkifli olbata, yabes Risqiyah, Arifatur Sri Widayati Tiran, Yessy Wisudaningsih, Endah Tri